{ "model": { "rank": 5813, "code": "thing-q26868", "model_id": "vr.tr.collagen", "name": "collagen", "purpose": "Enable an AI agent to recognise a collagen material, assess its structural and functional state, and determine which handling or transformation actions are supported by evidence.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q26868/", "tier": 2, "score": 64, "payload": { "layer": "wikidata", "aliases": [ "collagen type VI trimer", "fibrillar collagen trimer", "ossein", "short-chain collagen trimer", "basement membrane collagen trimer", "FACIT collagen trimer", "anchoring collagen complex", "transmembrane collagen trimer", "network-forming collagen trimer", "collagen type XXVI trimer", "collagen type XXVIII trimer", "collagen VI", "FACIT collagen", "non-fibrillar collagens", "Sharpey's fibres", "tropocollagen", "type-IV collagen", "Type XXVII collagen" ], "aliasCount": 18, "merged": 18, "knownIn": 64, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q26868", "url": "https://www.wikidata.org/wiki/Q26868", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-07T09:25:23Z", "providers": [ "Codex", "Grok" ], "missingProviders": [], "pass": 2, "cost": { "grok": { "usd": 0.0073491, "turns": 1, "seconds": 61.6, "error": null }, "codex": { "seconds": 88.6, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.3\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a07b2e-6c25-7c10-9ba2-997964d282cc\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: collagen\nRegistry id: vr.tr.collagen\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\nA Vercy" } } }, "metaModel": { "id": "THING-Q26868", "registryId": "vr.tr.collagen", "name": "collagen", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q26868/", "model": { "registry_id": "vr.tr.collagen", "name": "collagen", "purpose": "Enable an AI agent to recognise a collagen material, assess its structural and functional state, and determine which handling or transformation actions are supported by evidence.", "definition": "Collagen is a family of extracellular-matrix structural proteins in which three polypeptide α-chains fold into a right-handed triple helix (typically with a repeating Gly-X-Y motif) that polymerizes into fibrils, networks, or other supramolecular assemblies providing tensile strength in animal tissues.", "scope_statement": "This model owns collagen as a material, including its molecular identity, assembly, source, processing history, condition and demonstrated material capabilities; it distinguishes these from the tissue, organism or product containing it.", "in_scope": [ "Collagen identity, type composition and evidence distinguishing intact collagen from derivatives or substitutes", "Molecular integrity, triple-helical state and higher-order assembly", "Biological or recombinant origin, extraction history and material traceability", "Hydration, crosslinking, degradation and properties under specified conditions", "Evidence supporting material handling, assembly, processing and incorporation into another material" ], "out_of_scope": [ "Whole-tissue anatomy, physiology and disease", "Organism-level collagen synthesis, regulation and turnover", "Gelatin and collagen hydrolysates as independently characterised derivative materials", "Complete formulations, scaffolds, implants or other products containing collagen", "Clinical efficacy, nutritional benefit and patient-specific treatment decisions", "Manufacturing equipment and facility qualification" ], "distinguishing_features": [ "Require molecular identity evidence capable of distinguishing collagen from other structural proteins, rather than accepting tissue origin or a commercial label alone.", "Assess collagen identity separately from triple-helical integrity: collagen-derived material may retain identity evidence while losing the structure needed for an intact-collagen classification.", "Examine chain integrity and molecular-size distribution to distinguish intact material from extensively fragmented collagen peptides.", "Determine whether a collagen-like synthetic material has demonstrated collagen molecular identity or merely reproduces selected structural or mechanical behaviours.", "Distinguish the collagen constituent from a collagen-containing tissue or composite by recording what else is present and which component each measurement represents." ], "characteristics": [ { "name": "Collagen type and chain composition", "kind": "category", "unit_or_values": "Reported collagen type or types and constituent chains; mixed; unresolved", "why_it_matters": "A generic collagen label may conceal differences relevant to assembly and intended use." }, { "name": "Origin and material lineage", "kind": "relation", "unit_or_values": "Source organism and tissue, or recombinant production system; source lot; processing records", "why_it_matters": "Connects identity and condition evidence to the actual material being assessed." }, { "name": "Triple-helical integrity", "kind": "state", "unit_or_values": "Supported as retained, partly lost, lost or unresolved, with method and test conditions", "why_it_matters": "Separates molecular identity from the structural state underlying a proposed capability." }, { "name": "Chain integrity and size distribution", "kind": "measurement", "unit_or_values": "Molecular mass in kDa or method-specific distribution, with sample preparation", "why_it_matters": "Helps identify fragmentation and distinguish chain changes from changes in assembly." }, { "name": "Assembly state", "kind": "category", "unit_or_values": "Molecularly dispersed, fibrillar, networked, aggregated, mixed or unresolved", "why_it_matters": "Establishes the material organisation to which property measurements apply." }, { "name": "Collagen content", "kind": "measurement", "unit_or_values": "mg/mL or mass fraction, explicitly identifying dry or hydrated basis and assay", "why_it_matters": "Supports meaningful comparison of samples and interpretation of bulk behaviour." }, { "name": "Hydration", "kind": "measurement", "unit_or_values": "Water mass fraction or swelling ratio, with medium, temperature and equilibration time", "why_it_matters": "Makes condition-dependent dimensions and mechanical measurements interpretable." }, { "name": "Crosslinking and molecular modification", "kind": "category", "unit_or_values": "Native and introduced modifications, reaction method, measured extent or unresolved extent", "why_it_matters": "Records changes that may affect assembly, stability and compatibility with later processing." }, { "name": "Thermal structural transition", "kind": "measurement", "unit_or_values": "Transition temperature or interval in °C, with method, hydration and heating protocol", "why_it_matters": "Provides evidence for temperature limits without assuming one universal collagen threshold." }, { "name": "Mechanical response", "kind": "measurement", "unit_or_values": "Modulus or strength in Pa, strain as a fraction, with geometry, orientation, hydration and loading protocol", "why_it_matters": "Ties claims about load-bearing behaviour to the tested material form and conditions." } ], "affordances": [ "Classify a sample as collagen, a collagen-containing material, a derivative or unresolved using recorded identity and structural evidence.", "Select identity, conformation or fragmentation measurements that resolve a specific uncertainty.", "Assess whether proposed hydration, dissolution or assembly conditions are supported for the particular collagen material.", "Evaluate crosslinking, shaping or incorporation into a composite against the properties that must be retained.", "Compare storage and processing exposure with demonstrated structural stability limits.", "Route material for further characterisation, restricted use or rejection when its condition does not support the proposed action." ] }, "sources": [], "structure": { "bundles": [ { "id": "collagen-identity", "name": "Collagen identity", "description": "Establishes what collagen is present and where the material boundary lies.", "rationale": "The word collagen does not establish type, chain integrity or whether a sample is chiefly a derivative or composite.", "layers": [ { "id": "type-and-chain-evidence", "name": "Type and chain evidence", "description": "Records the basis for assigning collagen molecular identity.", "findings": [ { "id": "supported-collagen-assignment", "name": "Supported collagen assignment", "description": "Captures the strongest supported identity assignment and its unresolved alternatives.", "questions": [ { "text": "Which collagen types and constituent chains are supported by the available identity measurements?", "kind": "definition", "id": "supported-collagen-assignment-q01" }, { "text": "Can the methods used distinguish the assigned collagen from other proteins and collagen types plausibly present?", "kind": "measurement", "id": "supported-collagen-assignment-q02" } ] } ] }, { "id": "derivative-and-composite-boundaries", "name": "Derivative and composite boundaries", "description": "Separates collagen from altered descendants and surrounding constituents.", "findings": [ { "id": "material-classification-boundary", "name": "Material classification boundary", "description": "Records whether the assessed entity is intact collagen, altered collagen or a material containing collagen.", "questions": [ { "text": "What chain-integrity and conformation evidence supports distinguishing this material from gelatin or collagen hydrolysate?", "kind": "boundary", "id": "material-classification-boundary-q01" }, { "text": "Which non-collagen constituents are present, and do reported properties describe collagen itself or the complete mixture?", "kind": "boundary", "id": "material-classification-boundary-q02" } ] } ] } ] }, { "id": "origin-and-processing", "name": "Origin and processing", "description": "Connects the material to its biological or production origin and subsequent transformations.", "rationale": "Origin and processing are needed to interpret composition, structural alterations and transferability of evidence between lots.", "layers": [ { "id": "source-lineage", "name": "Source lineage", "description": "Identifies the source and traceable material population.", "findings": [ { "id": "traceable-collagen-source", "name": "Traceable collagen source", "description": "Records the origin at sufficient resolution to connect a sample with supporting evidence.", "questions": [ { "text": "From which organism and tissue, or recombinant production system, was this collagen obtained?", "kind": "provenance", "id": "traceable-collagen-source-q01" }, { "text": "Which source and lot records connect the tested sample to the material proposed for use?", "kind": "provenance", "id": "traceable-collagen-source-q02" } ] } ] }, { "id": "extraction-and-modification-history", "name": "Extraction and modification history", "description": "Records operations that may alter collagen chains, terminal regions or associated material.", "findings": [ { "id": "processing-dependent-identity", "name": "Processing-dependent identity", "description": "Connects extraction, purification and modification steps with measured changes.", "questions": [ { "text": "Which extraction, enzymatic treatment, purification, drying and chemical modification steps were applied?", "kind": "provenance", "id": "processing-dependent-identity-q01" }, { "text": "What evidence establishes whether those steps changed terminal regions, chain integrity or residual non-collagen content?", "kind": "measurement", "id": "processing-dependent-identity-q02" } ] } ] } ] }, { "id": "molecular-and-assembled-structure", "name": "Molecular and assembled structure", "description": "Distinguishes molecular conformation from the organisation of collagen into larger structures.", "rationale": "Molecular integrity and assembly answer different questions and cannot be inferred reliably from appearance alone.", "layers": [ { "id": "helical-and-chain-integrity", "name": "Helical and chain integrity", "description": "Assesses conformation and fragmentation independently.", "findings": [ { "id": "retained-molecular-structure", "name": "Retained molecular structure", "description": "Records evidence for structural retention, partial alteration or loss.", "questions": [ { "text": "What measurements support the reported triple-helical state under the current temperature, medium and hydration conditions?", "kind": "measurement", "id": "retained-molecular-structure-q01" }, { "text": "What chain-size or cleavage evidence distinguishes denaturation from fragmentation in this sample?", "kind": "measurement", "id": "retained-molecular-structure-q02" } ] } ] }, { "id": "assembly-and-crosslinks", "name": "Assembly and crosslinks", "description": "Describes supramolecular organisation and the links stabilising it.", "findings": [ { "id": "observed-collagen-organisation", "name": "Observed collagen organisation", "description": "Captures assembly morphology, orientation and crosslinking without presuming every collagen forms the same structure.", "questions": [ { "text": "Is the collagen dispersed, fibrillar, networked or aggregated, and which observations establish that assignment?", "kind": "measurement", "id": "observed-collagen-organisation-q01" }, { "text": "Which native or introduced crosslinks are demonstrated, and what is known about their extent and distribution?", "kind": "measurement", "id": "observed-collagen-organisation-q02" } ] } ] } ] }, { "id": "condition-and-stability", "name": "Condition and stability", "description": "Relates the present material state to its environment and exposure history.", "rationale": "An agent needs condition-specific evidence to judge whether collagen retains the properties required for its next use.", "layers": [ { "id": "hydration-and-medium", "name": "Hydration and medium", "description": "Records the surrounding conditions under which collagen is assessed.", "findings": [ { "id": "conditioned-material-state", "name": "Conditioned material state", "description": "Makes concentration, swelling and observed structure comparable across measurements.", "questions": [ { "text": "What are the collagen concentration, water content, temperature, pH and medium composition at assessment?", "kind": "measurement", "id": "conditioned-material-state-q01" }, { "text": "Does changing hydration or medium produce reversible swelling or dispersion, or evidence of persistent structural change?", "kind": "measurement", "id": "conditioned-material-state-q02" } ] } ] }, { "id": "damage-and-aging", "name": "Damage and aging", "description": "Tracks exposure and evidence of structural deterioration.", "findings": [ { "id": "stability-evidence", "name": "Stability evidence", "description": "Connects storage and processing exposures with retained or altered properties.", "questions": [ { "text": "What thermal, chemical, enzymatic, drying or freeze-thaw exposures has this material experienced?", "kind": "provenance", "id": "stability-evidence-q01" }, { "text": "Which comparisons with a suitable baseline establish retained integrity or detect denaturation, cleavage or unwanted aggregation?", "kind": "measurement", "id": "stability-evidence-q02" } ] } ] } ] }, { "id": "supported-material-actions", "name": "Supported material actions", "description": "Connects measured collagen properties with proposed handling and transformation.", "rationale": "Identity alone does not establish whether a particular collagen preparation can perform a required material function.", "layers": [ { "id": "functional-material-response", "name": "Functional material response", "description": "Records properties relevant to the proposed material role.", "findings": [ { "id": "demonstrated-capability", "name": "Demonstrated capability", "description": "Bounds capability claims by sample form, test conditions and required performance.", "questions": [ { "text": "Which measured mechanical, swelling, assembly or degradation behaviour is required for the proposed role?", "kind": "action", "id": "demonstrated-capability-q01" }, { "text": "Were those properties demonstrated for this collagen form and lot under conditions representative of that role?", "kind": "measurement", "id": "demonstrated-capability-q02" } ] } ] }, { "id": "transformation-and-reassessment", "name": "Transformation and reassessment", "description": "Defines evidence needed before and after changing the material.", "findings": [ { "id": "bounded-processing-choice", "name": "Bounded processing choice", "description": "Records supported processing conditions and the checks needed to confirm the result.", "questions": [ { "text": "What evidence supports the proposed dissolution, assembly, crosslinking, shaping or sterilisation conditions while retaining the required collagen properties?", "kind": "action", "id": "bounded-processing-choice-q01" }, { "text": "Which post-process measurements determine whether the result remains within this collagen model or should link to a derivative or composite model?", "kind": "boundary", "id": "bounded-processing-choice-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ "Type I collagen (bone, tendon, skin, dentin)", "Type II collagen (cartilage, vitreous humour)", "Type III collagen (reticular fibres, blood vessels, skin, uterus)", "Type IV collagen (basement membranes)", "Type V collagen (pericellular fibrils, often with type I)", "Type VI collagen (beaded-filament microfibrils)", "Type VII collagen (anchoring fibrils at the dermal-epidermal junction)", "Hydrolysed / denatured collagen (gelatin and collagen peptides used as ingredients)" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ { "scheme": "Wikidata", "value_or_pattern": "Q26868", "note": "item 'collagen'" }, { "scheme": "MeSH", "value_or_pattern": "D003094", "note": "Medical Subject Headings descriptor Collagen" }, { "scheme": "ChEBI", "value_or_pattern": "CHEBI:3815", "note": "chemical entity 'collagen'" }, { "scheme": "CAS Registry Number", "value_or_pattern": "9007-34-5", "note": "collagen (generic / extracted protein)" }, { "scheme": "EC number (EINECS)", "value_or_pattern": "232-697-4", "note": "collagen as a chemical substance in the EU inventory" }, { "scheme": "INCI", "value_or_pattern": "Collagen", "note": "cosmetic ingredient name; related names include Hydrolyzed Collagen, Soluble Collagen" }, { "scheme": "UniProt / gene (human type I)", "value_or_pattern": "COL1A1 (P02452), COL1A2 (P08123)", "note": "principal genes encoding type I collagen α-chains" } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-standards-and-regulation", "name": "Standards and regulation", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ "ISO 3496:1994 - Meat and meat products - Determination of hydroxyproline content (ISO; collagen inferred from hydroxyproline)", "ISO 3496 is the classic meat-chemistry method; later meat-protein / connective-tissue methods sit in ISO TC 34 meat-analysis series", "Ph. Eur. monograph Gelatin (European Pharmacopoeia / EDQM) - identity, bloom, microbial limits for pharmaceutical gelatin", "USP-NF Gelatin (United States Pharmacopeia) - pharmaceutical gelatin quality", "Regulation (EC) No 853/2004, Annex III, Section XIV - hygiene rules for collagen intended for human consumption (EU)", "Regulation (EC) No 2073/2005 - microbiological criteria applicable to collagen and gelatin for food use (EU)", "Regulation (EC) No 1223/2009 - cosmetic products; collagen ingredients listed by INCI with safety assessment (EU)", "21 CFR 182.1 / GRAS framework and 21 CFR 172 (food additives) as applied to gelatin and collagen hydrolysates in the United States (FDA)", "ISO 22442 series - Medical devices utilizing animal tissues and their derivatives (ISO; TSE/viral risk for animal-derived collagen implants)", "ASTM F2212 - Standard Guide for Characterization of Type I Collagen as Starting Material for Surgical Implants and Substrates (ASTM International)" ], "questions": [ { "id": "evidence-standards-and-regulation-q01", "text": "Which of these standards and regulation hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ "Structural protein of skin, bone, tendon, ligament, cartilage, cornea, blood-vessel wall and basement membranes in vertebrates", "Extracted bovine, porcine, piscine or recombinant collagen used as haemostatic sponges, wound dressings, dermal fillers, bone-graft matrices and tissue-engineering scaffolds", "Converted by heat/acid/alkali to gelatin for food (gelling, clarification), capsules and photographic/technical films", "Enzymatically hydrolysed collagen peptides sold as nutraceuticals and sports-nutrition ingredients", "Cosmetic moisturizers and film-formers labelled Collagen, Soluble Collagen or Hydrolyzed Collagen", "Leather and parchment are collagen-fibre networks of animal hide after tanning or drying", "Analytical marker of connective-tissue content in meat (hydroxyproline) and of animal glue in heritage conservation" ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ { "quantity": "Hydroxyproline content (as a collagen proxy)", "typical_range": "about 12-14% of collagen amino-acid residues; conversion factors ~7.1-8.0 g collagen per g hydroxyproline depending on tissue", "unit": "g/100 g protein or conversion factor (dimensionless)" }, { "quantity": "Triple-helix denaturation / melting temperature (Tm or Td)", "typical_range": "mammalian type I ~37-42 °C in dilute solution; fibrillar collagen in tissue higher; fish collagens often ~15-30 °C", "unit": "°C" }, { "quantity": "Fibril D-period (axial banding)", "typical_range": "67 (typically 64-67)", "unit": "nm" }, { "quantity": "Molecular mass of a tropocollagen molecule", "typical_range": "about 300 (three ~95-140 kDa α-chains)", "unit": "kDa" }, { "quantity": "Molecule length × diameter (tropocollagen)", "typical_range": "about 300 × 1.5", "unit": "nm" }, { "quantity": "Gelatin Bloom strength (derived product)", "typical_range": "food/pharma gelatin commonly 50-300", "unit": "Bloom (g)" }, { "quantity": "Isoelectric point of native collagen", "typical_range": "roughly 7-9 depending on type and telopeptide status; atelocollagen and gelatin lower and more variable", "unit": "pH" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ "Thermal or chemical denaturation unravels the triple helix, converting collagen to gelatin and collapsing tensile strength", "Enzymatic degradation by matrix metalloproteinases (MMP-1, MMP-8, MMP-13 collagenases) and bacterial collagenases in wound infection", "Cross-link deficiency (scurvy / lysyl-oxidase impairment) yields fragile vessels, poor wound healing and bone fragility", "Excess or disordered deposition (fibrosis, keloid, scleroderma, cirrhosis) stiffens organs", "Pathogenic variants in COL genes cause osteogenesis imperfecta, Ehlers-Danlos syndromes, Alport syndrome, dystrophic epidermolysis bullosa and Stickler syndrome", "Bovine- or ovine-sourced collagen and gelatin carry residual TSE (BSE/scrapie) risk unless sourced and processed under specified animal-tissue rules", "Immunogenicity and delayed hypersensitivity to heterologous (especially bovine) injectable collagen", "Heavy-metal, microbial or residual-chemical contamination of poorly processed food/cosmetic hydrolysates", "Over-hydrolysis of peptides destroys gelling function; under-hydrolysis leaves insoluble, poorly digestible fractions" ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-regional-variation", "name": "Regional variation", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ "Food and cosmetic collagen is commonly bovine or porcine in Europe and the Americas; fish-skin/scale collagen is preferred where porcine/bovine sources are religiously restricted (halal/kosher markets) or where BSE controls limit cattle tissue", "Japan, South Korea and parts of Southeast Asia have a large market for marine collagen peptides in beauty and functional foods", "EU food-hygiene law treats 'collagen' as a named product of animal origin with plant-approval and raw-material rules; US practice more often regulates the derived gelatin or hydrolysate under food-additive/GRAS and device frameworks", "Traditional animal glue (hide/bone glue) remains a named craft material in Europe and East Asia, while industrial users may simply specify 'gelatin' or 'collagen hydrolysate'", "Clinical injectable fillers: bovine collagen (historical Zyderm/Zyplast) largely displaced in many markets by hyaluronic acid; recombinant and porcine atelocollagen remain in some Asian and surgical-scaffold uses" ], "questions": [ { "id": "evidence-regional-variation-q01", "text": "Which of these regional variation hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ { "name": "Gelatin", "difference": "Gelatin is heat-denatured, water-soluble collagen that has lost the native triple helix and fibrillar D-banding; it gels on cooling. Native collagen remains insoluble fibrils with a collagenase-sensitive helix and ~67 nm banding on TEM." }, { "name": "Elastin", "difference": "Elastin is a hydrophobic, rubber-like ECM protein rich in desmosine/isodesmosine cross-links and low in hydroxyproline; collagen is glycine-rich, hydroxyproline-rich and tensile rather than elastic. Distinguish by amino-acid composition and by elastase vs. bacterial collagenase susceptibility." }, { "name": "Keratin", "difference": "Keratin is an intermediate-filament protein of epithelia and epidermal appendages (hair, nail, horn), rich in cysteine disulfides, not a Gly-X-Y triple helix. Collagen is mesenchymal/ECM and hydroxyproline-positive." }, { "name": "Fibronectin", "difference": "Fibronectin is a modular adhesive glycoprotein that binds integrin and collagen but is not itself a triple-helical fibril; it is identified by FN1 immunoreactivity and SDS-PAGE ~220-250 kDa subunits, not by hydroxyproline." }, { "name": "Chitosan / plant 'collagen' marketing substitutes", "difference": "True collagen is animal (or recombinant animal-sequence) protein with hydroxyproline and a triple helix. Plant hydrocolloids, yeast extracts and chitosan lack the collagen Gly-X-Y helix; hydroxyproline assay and circular-dichroism triple-helix signature separate them." }, { "name": "Reticulin (historical stain term)", "difference": "Silver-staining 'reticulin fibres' are largely type III collagen microfibrils, not a separate protein; immunohistochemistry for type III vs type I collagen replaces the old stain-only distinction." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of collagen this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Where does the registry place gelatin, collagen hydrolysates and collagen-mimetic materials, and what evidence should trigger links to those neighbouring entries?", "Which collagen types and material forms require distinct optional layers rather than one shared set of structural expectations?", "Which methods and acceptance criteria adequately establish identity, helical integrity and fragmentation for each intended material role?", "How should mixed-type preparations and partially denatured material be represented when no defensible single classification applies?", "Which processing and storage limits can be supported for specific sources and preparations, and how far can evidence transfer between lots?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 18, "questions": 28 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a collagen, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an AI agent to recognise a collagen material, assess its structural and functional state, and determine which handling or transformation actions are supported by evidence.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: collagen type VI trimer, fibrillar collagen trimer, ossein, short-chain collagen trimer, basement membrane collagen trimer, FACIT collagen trimer, anchoring collagen complex, transmembrane collagen trimer, network-forming collagen trimer, collagen type XXVI trimer, collagen type XXVIII trimer, collagen VI.", "18 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 64 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a collagen, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "collagen type VI trimer", "fibrillar collagen trimer", "ossein", "short-chain collagen trimer", "basement membrane collagen trimer", "FACIT collagen trimer", "anchoring collagen complex", "transmembrane collagen trimer", "network-forming collagen trimer", "collagen type XXVI trimer", "collagen type XXVIII trimer", "collagen VI" ] } ], "standing": "Described in 64 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 18 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one collagen from another, and a collagen from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a collagen sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a collagen from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a collagen is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a collagen is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a collagen is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a collagen is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a collagen is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a collagen is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a collagen passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a collagen between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a collagen, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a collagen is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a collagen and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a collagen is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a collagen performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a collagen.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a collagen at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a collagen there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What collagen is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name collagen unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of collagen exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How collagen behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of collagen, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is collagen incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How collagen can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is collagen classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover collagen, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a collagen came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a collagen and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a collagen is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a collagen, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a collagen, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a collagen is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }