{ "model": { "rank": 6335, "code": "thing-q26963", "model_id": "vr.tr.progesterone", "name": "progesterone", "purpose": "Enable an AI agent to recognise progesterone, assess the identity and condition of a material or measurement containing it, and determine which handling or interpretation actions are justified.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q26963/", "tier": 2, "score": 61, "payload": { "layer": "wikidata", "aliases": [], "aliasCount": 0, "merged": 0, "knownIn": 61, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q26963", "url": "https://www.wikidata.org/wiki/Q26963", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-07T13:51:54Z", "providers": [ "Codex", "Grok" ], "missingProviders": [], "pass": 2, "cost": { "grok": { "usd": 0.00235926, "turns": 1, "seconds": 22.7, "error": null }, "codex": { "seconds": 86, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.3\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a07c22-7a2a-77e2-9461-0bcf6a6c6e35\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: progesterone\nRegistry id: vr.tr.progesterone\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n" } } }, "metaModel": { "id": "THING-Q26963", "registryId": "vr.tr.progesterone", "name": "progesterone", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q26963/", "model": { "registry_id": "vr.tr.progesterone", "name": "progesterone", "purpose": "Enable an AI agent to recognise progesterone, assess the identity and condition of a material or measurement containing it, and determine which handling or interpretation actions are justified.", "definition": "Progesterone is an endogenous C21 steroid hormone (pregn-4-ene-3,20-dione) produced mainly by the corpus luteum, placenta and adrenal cortex that binds the nuclear progesterone receptor and is required for endometrial secretory transformation, maintenance of pregnancy, and several extra-reproductive signalling roles.", "scope_statement": "This draft model owns progesterone as the molecular substance registered as vr.tr.progesterone in PHY / PHY.MAT, including its identity, material condition, measured presence and contextual relations to biological systems and preparations.", "in_scope": [ "Molecular identity and evidence distinguishing progesterone from related steroids.", "Progesterone content, purity and physical presentation in identified materials.", "Measurements of progesterone with specimen, method, timing and uncertainty.", "Relations to endogenous production, administered preparations and biological activity.", "Evidence supporting storage, analytical use and referral to clinical or product-specific decisions." ], "out_of_scope": [ "Other progestogens, progesterone metabolites and steroid precursors as independently modelled substances.", "Whole reproductive systems, pregnancy states and endocrine disorders.", "Complete medicinal products, their excipients, authorisations and manufacturing specifications.", "Patient-specific diagnoses, prescribing decisions and treatment protocols.", "Laboratory instruments and assay procedures as independently managed systems." ], "distinguishing_features": [ "Require agreement with progesterone's stereochemically specified structure, rather than its name or molecular formula alone; PubChem identifies it as CID 5994, C21H30O2, with carbonyl groups at positions 3 and 20 and a C4-C5 double bond. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/Progesterone)", "Compare the candidate's complete structure against progesterone before accepting a label such as progestogen, progestin or progesterone-like as an identity match.", "Check stereochemistry explicitly: a matching formula does not distinguish progesterone from 17-isoprogesterone. [PubChem: Isoprogesterone](https://pubchem.ncbi.nlm.nih.gov/compound/Isoprogesterone)", "Distinguish the progesterone ingredient from a preparation containing it: micronized progesterone capsules have formulation-specific properties and are not simply a quantity of pure substance. [DailyMed](https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=0bf317a8-96d6-849d-7850-9084205a5315)", "Require the analytical target to be progesterone itself before treating a related steroid measurement or a biological activity result as a progesterone concentration." ], "characteristics": [ { "name": "Molecular identity confidence", "kind": "state", "unit_or_values": "label-only | analytically supported | conflicting | unresolved", "why_it_matters": "Determines whether the material can be treated as progesterone rather than an analogue or misidentified steroid." }, { "name": "Occurrence context", "kind": "category", "unit_or_values": "bulk substance | reference material | preparation ingredient | biological analyte", "why_it_matters": "Determines which quality criteria and actions apply to the occurrence." }, { "name": "Progesterone content", "kind": "measurement", "unit_or_values": "mg, mg/g or mass fraction, with denominator and analytical basis", "why_it_matters": "Separates the amount of progesterone from the total amount of a mixture or preparation." }, { "name": "Biological concentration", "kind": "measurement", "unit_or_values": "nmol/L or ng/mL, with matrix, collection time and measured fraction", "why_it_matters": "Supports comparison only when the measurement context and units are compatible." }, { "name": "Analytical purity", "kind": "measurement", "unit_or_values": "percentage with method and basis; identified impurity concentrations", "why_it_matters": "Supports assessment of suitability for a stated analytical or material use." }, { "name": "Physical presentation", "kind": "category", "unit_or_values": "solid | dissolved | suspended | dispersed in a preparation; particle-size description where relevant", "why_it_matters": "Guides sampling, preparation and interpretation of material-specific performance." }, { "name": "Source attribution", "kind": "relation", "unit_or_values": "linked manufacturing source, biological compartment or administration event; confidence stated", "why_it_matters": "Prevents molecular identity from being mistaken for evidence of biological or manufacturing origin." }, { "name": "Measurement comparability", "kind": "state", "unit_or_values": "comparable | conditionally comparable | incompatible | unresolved", "why_it_matters": "Controls whether observations may support a trend or shared interpretation." }, { "name": "Material suitability", "kind": "state", "unit_or_values": "supported for stated use | restricted | quarantined | unresolved", "why_it_matters": "Connects identity, condition and specification evidence to a concrete permitted use." } ], "affordances": [ "Resolve a progesterone identity claim against structural and analytical evidence.", "Compare progesterone measurements after checking matrix, method, units and collection context.", "Assess a progesterone batch or aliquot against the specification for its intended use.", "Select or request an appropriate identity, content or interference investigation.", "Link measured progesterone to biological and administration context without assuming its source.", "Support storage, quarantine or referral decisions using applicable material or product documentation." ] }, "sources": [ { "id": "src-who-ccds", "title": "WHO Collaborating Centre for Drug Statistics Methodology: ATC/DDD Index - G03DA04 progesterone", "url": "https://atcddd.fhi.no/atc_ddd_index/?code=G03DA04", "what_it_supports": "Official ATC classification and defined daily dose for progesterone as a pharmaceutical substance.", "url_status": "live" }, { "id": "src-pubchem", "title": "PubChem Compound Summary: Progesterone (CID 5994)", "url": "https://pubchem.ncbi.nlm.nih.gov/compound/Progesterone", "what_it_supports": "IUPAC name, formula, CAS, InChIKey, UNII and physicochemical identifiers.", "url_status": "live" }, { "id": "src-ema-smc", "title": "Utrogestan 100 mg Capsules - Summary of Product Characteristics", "url": "https://www.medicines.org.uk/emc/product/353/smpc", "what_it_supports": "Licensed indications, routes, typical doses, contraindications and safety profile of micronized progesterone.", "url_status": "live" } ], "structure": { "bundles": [ { "id": "progesterone-identity", "name": "Progesterone identity", "description": "Establish what evidence makes a substance occurrence progesterone.", "rationale": "Steroid similarity and broad hormone terminology can conceal a different molecule.", "layers": [ { "id": "structure-and-stereochemistry", "name": "Structure and stereochemistry", "description": "Resolve molecular identity beyond a formula or label.", "findings": [ { "id": "progesterone-structure-match", "name": "Progesterone structure match", "description": "Record whether an identity claim matches the reference structure and its stereochemistry.", "questions": [ { "text": "Which authoritative structure and identifier define progesterone for this occurrence?", "kind": "definition", "id": "progesterone-structure-match-q01" }, { "text": "What analytical evidence distinguishes the candidate from structurally similar steroids and stereoisomers?", "kind": "measurement", "id": "progesterone-structure-match-q02" } ] } ] }, { "id": "substance-and-class-boundaries", "name": "Substance and class boundaries", "description": "Separate progesterone from neighbouring substances and preparations.", "findings": [ { "id": "progesterone-name-resolution", "name": "Progesterone name resolution", "description": "Determine whether a name refers to the molecule, a class of agents or a product containing it.", "questions": [ { "text": "Does the supplied name identify progesterone itself, a different progestogen or a medicinal product?", "kind": "boundary", "id": "progesterone-name-resolution-q01" }, { "text": "Which ingredient or structural record supports mapping this name to vr.tr.progesterone?", "kind": "provenance", "id": "progesterone-name-resolution-q02" } ] } ] } ] }, { "id": "progesterone-material-quality", "name": "Progesterone material quality", "description": "Assess progesterone as a physical material with a particular composition and condition.", "rationale": "An identity match alone does not establish the content or suitability of a batch, standard or preparation.", "layers": [ { "id": "content-and-related-substances", "name": "Content and related substances", "description": "Distinguish progesterone quantity from impurities and carrier material.", "findings": [ { "id": "progesterone-content-basis", "name": "Progesterone content basis", "description": "Record measured progesterone content and the basis on which purity is reported.", "questions": [ { "text": "How much progesterone is present, and is the reported value based on total material, dried material or another denominator?", "kind": "measurement", "id": "progesterone-content-basis-q01" }, { "text": "Which related steroids, degradation products or other impurities were assessed against the intended-use specification?", "kind": "measurement", "id": "progesterone-content-basis-q02" } ] } ] }, { "id": "presentation-and-stability", "name": "Presentation and stability", "description": "Connect physical form and exposure history to supported usability.", "findings": [ { "id": "progesterone-condition-assessment", "name": "Progesterone condition assessment", "description": "Record the material's physical presentation and evidence that its condition remains acceptable.", "questions": [ { "text": "Is progesterone present as a solid, solution or suspension, and what solvent, carrier or particle-size information is relevant?", "kind": "definition", "id": "progesterone-condition-assessment-q01" }, { "text": "What storage, opening or preparation history must be checked against the applicable stability evidence?", "kind": "provenance", "id": "progesterone-condition-assessment-q02" }, { "text": "Does the documented condition support use, require retesting or justify quarantine?", "kind": "action", "id": "progesterone-condition-assessment-q03" } ] } ] } ] }, { "id": "progesterone-measurement", "name": "Progesterone measurement", "description": "Establish what a progesterone result measures and whether it can be compared or interpreted.", "rationale": "A numerical progesterone result is incomplete without its specimen and analytical context.", "layers": [ { "id": "specimen-and-measurand", "name": "Specimen and measurand", "description": "Define the sampled occurrence and reported quantity.", "findings": [ { "id": "progesterone-result-context", "name": "Progesterone result context", "description": "Bind the result to a matrix, collection event, measured fraction and unit.", "questions": [ { "text": "Which specimen matrix and collection time does the progesterone result describe?", "kind": "provenance", "id": "progesterone-result-context-q01" }, { "text": "Does the result represent total progesterone, a specified fraction or another explicitly defined measurand?", "kind": "definition", "id": "progesterone-result-context-q02" }, { "text": "What value, units, uncertainty and reporting limits accompany the observation?", "kind": "measurement", "id": "progesterone-result-context-q03" } ] } ] }, { "id": "specificity-and-comparability", "name": "Specificity and comparability", "description": "Assess analytical limitations before combining progesterone observations.", "findings": [ { "id": "progesterone-assay-fitness", "name": "Progesterone assay fitness", "description": "Record evidence that the method is sufficiently specific and sensitive for the intended interpretation.", "questions": [ { "text": "What method, calibration and interference evidence support measuring progesterone in this matrix and concentration range?", "kind": "measurement", "id": "progesterone-assay-fitness-q01" }, { "text": "Do differences in assay, specimen handling or measured fraction prevent comparison with another result?", "kind": "boundary", "id": "progesterone-assay-fitness-q02" }, { "text": "What unresolved interference or reporting-limit issue warrants repeat or confirmatory measurement?", "kind": "action", "id": "progesterone-assay-fitness-q03" } ] } ] } ] }, { "id": "progesterone-biological-context", "name": "Progesterone biological context", "description": "Relate progesterone observations to their organism, timing and possible sources.", "rationale": "Concentration alone cannot establish biological origin, tissue response or a clinical state.", "layers": [ { "id": "source-and-timing", "name": "Source and timing", "description": "Record the context needed to evaluate a biological observation.", "findings": [ { "id": "progesterone-observation-attribution", "name": "Progesterone observation attribution", "description": "Distinguish documented context from inferred source attribution.", "questions": [ { "text": "Which species, compartment and relevant reproductive or endocrine context accompany the observation?", "kind": "provenance", "id": "progesterone-observation-attribution-q01" }, { "text": "What collection timing relative to documented cycle events, pregnancy stage or progesterone administration is available?", "kind": "provenance", "id": "progesterone-observation-attribution-q02" }, { "text": "What evidence supports an endogenous, administered or mixed contribution, and what remains unassignable?", "kind": "boundary", "id": "progesterone-observation-attribution-q03" } ] } ] }, { "id": "concentration-and-response", "name": "Concentration and response", "description": "Separate measured presence from claims about biological effect.", "findings": [ { "id": "progesterone-interpretation-boundary", "name": "Progesterone interpretation boundary", "description": "State what contextual evidence permits an interpretation and where another model must decide.", "questions": [ { "text": "Which reference population or decision framework matches this specimen, assay and biological context?", "kind": "boundary", "id": "progesterone-interpretation-boundary-q01" }, { "text": "What independent evidence supports a claimed tissue response or physiological interpretation?", "kind": "measurement", "id": "progesterone-interpretation-boundary-q02" }, { "text": "Which proposed conclusions require a patient, reproductive-state or disease model rather than this substance model?", "kind": "boundary", "id": "progesterone-interpretation-boundary-q03" } ] } ] } ] }, { "id": "progesterone-use-decisions", "name": "Progesterone use decisions", "description": "Connect evidence about progesterone to justified handling and use.", "rationale": "Molecular sameness does not establish that materials, formulations or routes can serve the same purpose.", "layers": [ { "id": "preparation-and-exposure", "name": "Preparation and exposure", "description": "Link progesterone to the preparation and administration evidence relevant to a proposed use.", "findings": [ { "id": "progesterone-preparation-link", "name": "Progesterone preparation link", "description": "Record the containing product and prevent unsupported transfer of exposure claims between preparations.", "questions": [ { "text": "Which product, progesterone strength, formulation and route are linked to the proposed use?", "kind": "provenance", "id": "progesterone-preparation-link-q01" }, { "text": "What evidence supports any proposed equivalence between the progesterone preparations being compared?", "kind": "boundary", "id": "progesterone-preparation-link-q02" } ] } ] }, { "id": "fitness-and-action", "name": "Fitness and action", "description": "Determine which action is supported for the particular progesterone occurrence.", "findings": [ { "id": "progesterone-use-disposition", "name": "Progesterone use disposition", "description": "Connect intended use to identity, quality and applicable handling requirements.", "questions": [ { "text": "Is the progesterone intended for calibration, research, manufacture or a linked medicinal use, and which specification governs that purpose?", "kind": "definition", "id": "progesterone-use-disposition-q01" }, { "text": "Which current material safety document or product instruction governs handling this particular preparation?", "kind": "provenance", "id": "progesterone-use-disposition-q02" }, { "text": "Does the evidence support the requested action, or must the agent obtain missing evidence or refer the decision to the responsible laboratory or clinical workflow?", "kind": "action", "id": "progesterone-use-disposition-q03" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ "endogenous circulating progesterone", "micronized oral/vaginal progesterone (bioidentical)", "intramuscular progesterone in oil", "synthetic progestins (distinct class, often grouped in practice)", "17-alpha-hydroxyprogesterone caproate", "veterinary progesterone (CIDR, implants, assays)", "analytical/reference-standard progesterone" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of progesterone this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Which existing Vercy publication, if any, already owns progesterone and should receive this registry link instead of a separate model?", "Which identity and impurity specifications should govern analytical, research and pharmaceutical progesterone materials?", "Which specimen matrices, species and assay methods have sufficiently validated progesterone reference information for inclusion?", "What formulation-specific stability and exposure evidence supports handling rules or comparisons between progesterone preparations?", "Under which sampling conditions can endogenous and administered contributions be distinguished, and when must source attribution remain unresolved?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 11, "questions": 27 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a progesterone, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an AI agent to recognise progesterone, assess the identity and condition of a material or measurement containing it, and determine which handling or interpretation actions are justified.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Described in 61 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a progesterone, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [], "standing": "Described in 61 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one progesterone from another, and a progesterone from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a progesterone sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a progesterone from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a progesterone is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a progesterone is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a progesterone is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a progesterone is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a progesterone is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a progesterone is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a progesterone passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a progesterone between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a progesterone, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a progesterone is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a progesterone and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a progesterone is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a progesterone performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a progesterone.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a progesterone at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a progesterone there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What progesterone is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name progesterone unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of progesterone exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How progesterone behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of progesterone, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is progesterone incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How progesterone can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is progesterone classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover progesterone, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a progesterone came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a progesterone and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a progesterone is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a progesterone, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a progesterone, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a progesterone is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }