{ "model": { "rank": 2191, "code": "thing-q28086552", "model_id": "vr.tr.nicotine", "name": "(−)-nicotine", "purpose": "Enable an AI agent to identify (−)-nicotine, assess the identity and condition of material containing it, and determine whether a proposed handling or use is supported by evidence.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q28086552/", "tier": 2, "score": 112, "payload": { "layer": "wikidata", "aliases": [], "aliasCount": 0, "merged": 0, "knownIn": 112, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q28086552", "url": "https://www.wikidata.org/wiki/Q28086552", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-07T10:23:50Z", "providers": [ "Codex", "Grok" ], "missingProviders": [], "pass": 2, "cost": { "grok": { "usd": 0.00233478, "turns": 1, "seconds": 22.7, "error": null }, "codex": { "seconds": 91, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.3\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a07b63-e7b9-71b0-bf4c-2a3056d6a189\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: (−)-nicotine\nRegistry id: vr.tr.nicotine\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\nA V" } } }, "metaModel": { "id": "THING-Q28086552", "registryId": "vr.tr.nicotine", "name": "(−)-nicotine", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q28086552/", "model": { "registry_id": "vr.tr.nicotine", "name": "(−)-nicotine", "purpose": "Enable an AI agent to identify (−)-nicotine, assess the identity and condition of material containing it, and determine whether a proposed handling or use is supported by evidence.", "definition": "The naturally occurring (S)-enantiomer of nicotine, a pyridine-pyrrolidine alkaloid that is the principal psychoactive constituent of Nicotiana species and a high-affinity agonist of nicotinic acetylcholine receptors.", "scope_statement": "This model owns the stereospecific substance identity of (−)-nicotine under vr.tr.nicotine and the evidence needed to assess its presence, chemical form, quantity, condition and handling constraints in a particular material.", "in_scope": [ "Stereochemical identity and discrimination from other nicotine compositions", "Free-base identity and relations to protonated nicotine, salts and mixtures", "Nicotine assay, enantiomeric composition and relevant impurities", "Material condition, storage history and analytical evidence of change", "Substance-specific handling constraints and suitability for a declared use" ], "out_of_scope": [ "Tobacco plants, cultivation and whole-leaf composition", "Complete formulations and delivery performance of nicotine-containing products", "Patient treatment, dosing, dependence and clinical outcomes", "Detailed synthesis, extraction and purification processes", "Complete models of nicotine salts, metabolites and other alkaloids", "Facility-wide chemical safety and waste-management systems" ], "distinguishing_features": [ "Require evidence for the S-configured nicotine structure, rather than accepting an unspecified nicotine label: PubChem identifies (−)-nicotine with (S)-3-(1-methylpyrrolidin-2-yl)pyridine. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/L-Nicotine)", "Use an enantioselective measurement to distinguish S-enriched nicotine from R-nicotine and racemic nicotine; a total-nicotine assay alone does not establish the claimed stereochemical composition.", "Check protonation, counterions and composition to distinguish neat free-base material from a nicotine salt or nicotine-containing solution.", "Require analytical discrimination from related alkaloids and transformation products; a product name, colour or nominal molecular mass alone is insufficient.", "Treat optical rotation as condition-dependent supporting evidence, recording wavelength, temperature, solvent and concentration before comparing results." ], "characteristics": [ { "name": "Stereospecific identity confidence", "kind": "state", "unit_or_values": "claimed | supported | conflicting | unresolved", "why_it_matters": "Determines whether the material can be identified specifically as (−)-nicotine." }, { "name": "Nicotine enantiomer composition", "kind": "measurement", "unit_or_values": "S and R mole fractions or percentages, with method and uncertainty", "why_it_matters": "Separates stereochemical purity from overall chemical purity." }, { "name": "Chemical presentation", "kind": "category", "unit_or_values": "free base | protonated species in solution | identified salt | mixed | unresolved", "why_it_matters": "Prevents treating every nicotine-bearing material as neat free-base nicotine." }, { "name": "Counterion or host matrix", "kind": "relation", "unit_or_values": "identified counterion, solvent, formulation or biological matrix", "why_it_matters": "Provides context for interpreting assay, speciation and handling evidence." }, { "name": "Nicotine content", "kind": "measurement", "unit_or_values": "mg, mg/g, mg/mL or mol/L, explicitly stating total nicotine versus S-nicotine and free-base-equivalent versus salt basis", "why_it_matters": "Prevents incompatible quantities from being compared or substituted." }, { "name": "Optical rotation", "kind": "measurement", "unit_or_values": "observed degrees or specific rotation with convention, wavelength, temperature, solvent and concentration", "why_it_matters": "Supports stereochemical assessment only when measurement conditions are interpretable." }, { "name": "Solution acidity and nicotine speciation", "kind": "measurement", "unit_or_values": "pH where applicable; estimated or measured species fractions with medium, temperature and method", "why_it_matters": "Connects the nicotine moiety to its actual chemical state in the material." }, { "name": "Impurity and transformation-product profile", "kind": "measurement", "unit_or_values": "identified substances and concentrations, reporting limits and unresolved analytical signals", "why_it_matters": "Supports decisions about contamination, deterioration and fitness for use." }, { "name": "Storage and exposure history", "kind": "relation", "unit_or_values": "dated temperature, light, air, moisture, container and opening records", "why_it_matters": "Allows current analytical results to be interpreted against the material's history." }, { "name": "Disposition for intended use", "kind": "state", "unit_or_values": "unassessed | accepted for specified use | restricted | quarantined | rejected", "why_it_matters": "Makes acceptance conditional on a declared use, supporting evidence and applicable requirements." } ], "affordances": [ "Resolve a nicotine identity claim against structural and stereochemical evidence.", "Request and interpret assays that distinguish total nicotine, S-nicotine and relevant impurities.", "Compare nicotine quantities after verifying chemical form and reporting basis.", "Link the substance to a salt, formulation or sample without conflating their identities.", "Assess whether storage history or analytical changes require retesting or quarantine.", "Route proposed handling, transfer or disposal through applicable substance-specific controls." ] }, "sources": [], "structure": { "bundles": [ { "id": "nicotine-stereochemical-identity", "name": "Nicotine stereochemical identity", "description": "Establishes whether the evidence identifies the registered S-configured nicotine substance.", "rationale": "The minus sign carries identity information that generic nicotine records can omit.", "layers": [ { "id": "molecular-identity", "name": "Molecular identity", "description": "Connects the name to an explicitly stereochemical molecular identity.", "findings": [ { "id": "structure-and-identifier-agreement", "name": "Structure and identifier agreement", "description": "Record whether structural evidence and identifiers consistently designate (−)-nicotine.", "questions": [ { "text": "Does the assigned structure explicitly specify S configuration at nicotine's stereogenic centre?", "kind": "definition", "id": "structure-and-identifier-agreement-q01" }, { "text": "Which authoritative identity record and sample-specific evidence support that assignment?", "kind": "provenance", "id": "structure-and-identifier-agreement-q02" } ] } ] }, { "id": "enantiomer-discrimination", "name": "Enantiomer discrimination", "description": "Separates verified stereochemical composition from an unqualified nicotine assay.", "findings": [ { "id": "s-and-r-composition", "name": "S and R composition", "description": "Record the measured enantiomer proportions and the limitations of supporting evidence.", "questions": [ { "text": "What S and R proportions were measured, by which enantioselective method and with what detection limits?", "kind": "measurement", "id": "s-and-r-composition-q01" }, { "text": "If optical rotation supports identification, are its conditions and reference comparison recorded?", "kind": "measurement", "id": "s-and-r-composition-q02" }, { "text": "What use-specific acceptance rule distinguishes acceptable S-enriched material from an unresolved or mixed-enantiomer sample?", "kind": "boundary", "id": "s-and-r-composition-q03" } ] } ] } ] }, { "id": "nicotine-form-and-matrix", "name": "Nicotine form and matrix", "description": "Locates the nicotine identity within its actual chemical presentation.", "rationale": "Free base, protonated nicotine and nicotine-bearing mixtures require different interpretations of the same nicotine claim.", "layers": [ { "id": "protonation-and-counterions", "name": "Protonation and counterions", "description": "Records evidence for the material's nicotine species and salt relationships.", "findings": [ { "id": "chemical-form-assignment", "name": "Chemical form assignment", "description": "Keep free-base identity distinct from the identity of a complete salt or solution.", "questions": [ { "text": "Is nicotine present as free base, protonated species or a mixture, and what establishes this?", "kind": "definition", "id": "chemical-form-assignment-q01" }, { "text": "Where a salt is claimed, which counterion and stoichiometry are established, and which neighbouring model owns the complete salt?", "kind": "boundary", "id": "chemical-form-assignment-q02" } ] } ] }, { "id": "matrix-dependent-state", "name": "Matrix-dependent state", "description": "Records the medium needed to interpret nicotine's state in a sample.", "findings": [ { "id": "medium-and-speciation-evidence", "name": "Medium and speciation evidence", "description": "Attach solvent, acidity and temperature context to claims about nicotine species.", "questions": [ { "text": "What solvent or host matrix contains the nicotine, and is its composition adequately known?", "kind": "provenance", "id": "medium-and-speciation-evidence-q01" }, { "text": "Which measured conditions and validated assumptions support any reported unprotonated fraction?", "kind": "measurement", "id": "medium-and-speciation-evidence-q02" } ] } ] } ] }, { "id": "nicotine-assay-and-composition", "name": "Nicotine assay and composition", "description": "Determines how much relevant nicotine is present and what accompanies it.", "rationale": "A concentration without stereochemical and chemical-form basis can misrepresent the registered substance.", "layers": [ { "id": "quantity-basis", "name": "Quantity basis", "description": "Makes nicotine measurements comparable without silently changing their meaning.", "findings": [ { "id": "assay-meaning-and-conversion", "name": "Assay meaning and conversion", "description": "Record the analyte, denominator and conversion basis of every nicotine quantity.", "questions": [ { "text": "Does the reported value quantify total nicotine, S-nicotine, free-base-equivalent nicotine or the mass of a complete salt?", "kind": "measurement", "id": "assay-meaning-and-conversion-q01" }, { "text": "Are concentration basis, uncertainty and any density or stoichiometry needed for conversion available?", "kind": "measurement", "id": "assay-meaning-and-conversion-q02" } ] } ] }, { "id": "analytical-selectivity", "name": "Analytical selectivity", "description": "Tests whether the analytical evidence separates nicotine from accompanying substances.", "findings": [ { "id": "impurities-and-assay-interference", "name": "Impurities and assay interference", "description": "Record relevant impurities, unresolved signals and limitations of the nicotine assay.", "questions": [ { "text": "Which related alkaloids, residual process materials or transformation products were sought and quantified?", "kind": "measurement", "id": "impurities-and-assay-interference-q01" }, { "text": "What demonstrates that matrix effects or unresolved compounds do not invalidate the reported nicotine result?", "kind": "provenance", "id": "impurities-and-assay-interference-q02" } ] } ] } ] }, { "id": "nicotine-condition-and-history", "name": "Nicotine condition and history", "description": "Connects present composition to production, storage and subsequent changes.", "rationale": "Neither an origin claim nor an old certificate establishes the current condition of a nicotine sample.", "layers": [ { "id": "origin-and-lot-continuity", "name": "Origin and lot continuity", "description": "Separates material provenance from chemical identity and preserves sample traceability.", "findings": [ { "id": "origin-claim-evidence", "name": "Origin claim evidence", "description": "Record extraction or synthesis claims without using them as substitutes for stereochemical measurement.", "questions": [ { "text": "What evidence supports the claimed nicotine origin and connects the tested sample to the supplied lot?", "kind": "provenance", "id": "origin-claim-evidence-q01" }, { "text": "Is origin relevant to the intended use, and has it been kept separate from proof of S configuration and purity?", "kind": "boundary", "id": "origin-claim-evidence-q02" } ] } ] }, { "id": "change-during-storage", "name": "Change during storage", "description": "Assesses whether the material remains supported by its existing qualification evidence.", "findings": [ { "id": "condition-change-and-retest", "name": "Condition change and retest", "description": "Compare exposure history and current measurements with a documented baseline.", "questions": [ { "text": "What air, light, moisture, temperature and container exposures occurred after the last qualifying assay?", "kind": "provenance", "id": "condition-change-and-retest-q01" }, { "text": "Have nicotine assay, impurity profile or physical observations changed relative to the baseline?", "kind": "measurement", "id": "condition-change-and-retest-q02" }, { "text": "Which evidence-based criterion requires retesting, quarantine or rejection?", "kind": "action", "id": "condition-change-and-retest-q03" } ] } ] } ] }, { "id": "nicotine-handling-and-use-decisions", "name": "Nicotine handling and use decisions", "description": "Connects the assessed material to a specific proposed operation and its applicable controls.", "rationale": "Nicotine can be absorbed through skin and presents serious toxicity hazards, making exposure context relevant to handling decisions. [CDC/NIOSH](https://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750028.html)", "layers": [ { "id": "exposure-context", "name": "Exposure context", "description": "Identifies how the proposed operation could expose people to the actual nicotine-bearing material.", "findings": [ { "id": "operation-specific-controls", "name": "Operation-specific controls", "description": "Use the material's concentration, form and operation to identify applicable handling requirements.", "questions": [ { "text": "What nicotine quantity, concentration, matrix and potential exposure routes are involved in the proposed operation?", "kind": "measurement", "id": "operation-specific-controls-q01" }, { "text": "Which current safety data and approved procedure establish the required containment, protective equipment and incident response?", "kind": "action", "id": "operation-specific-controls-q02" } ] } ] }, { "id": "use-specific-disposition", "name": "Use-specific disposition", "description": "Makes acceptance or restriction explicit for a named purpose.", "findings": [ { "id": "qualification-and-permitted-next-step", "name": "Qualification and permitted next step", "description": "Record the evidence and authority supporting analysis, use, transfer, continued storage or disposal.", "questions": [ { "text": "Which identity, enantiomeric composition, assay and impurity requirements apply to the declared use?", "kind": "boundary", "id": "qualification-and-permitted-next-step-q01" }, { "text": "Do the available results and applicable jurisdictional requirements support the proposed action, or require restriction or further review?", "kind": "action", "id": "qualification-and-permitted-next-step-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Reported by the breadth pass; each item needs checking against its source before it becomes normative.", "evidence": [ "tobacco-leaf alkaloid", "pharmaceutical nicotine (NRT)", "e-liquid / vaping nicotine", "synthetic (S)-nicotine", "nicotine salt", "pesticide-grade nicotine" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of (−)-nicotine this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Does the registry intend this entry to own only neutral (S)-nicotine, or also nicotine-moiety records within protonated forms and salts?", "What enantiomeric acceptance thresholds and analytical methods are appropriate for each intended use?", "Which impurity and transformation-product panels are required for the relevant origins, matrices and grades?", "What validated storage, container-compatibility and retest criteria apply to each material presentation?", "Which jurisdiction, product category and operational setting determine the applicable handling, transfer and disposal requirements?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 11, "questions": 23 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a (−)-nicotine, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an AI agent to identify (−)-nicotine, assess the identity and condition of material containing it, and determine whether a proposed handling or use is supported by evidence.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Described in 112 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a (−)-nicotine, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [], "standing": "Described in 112 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one (−)-nicotine from another, and a (−)-nicotine from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a (−)-nicotine sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a (−)-nicotine from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a (−)-nicotine is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a (−)-nicotine is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a (−)-nicotine is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a (−)-nicotine is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a (−)-nicotine is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a (−)-nicotine is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a (−)-nicotine passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a (−)-nicotine between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a (−)-nicotine, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a (−)-nicotine is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a (−)-nicotine and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a (−)-nicotine is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a (−)-nicotine performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a (−)-nicotine.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a (−)-nicotine at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a (−)-nicotine there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What (−)-nicotine is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name (−)-nicotine unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of (−)-nicotine exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How (−)-nicotine behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of (−)-nicotine, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is (−)-nicotine incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How (−)-nicotine can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is (−)-nicotine classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover (−)-nicotine, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a (−)-nicotine came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a (−)-nicotine and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a (−)-nicotine is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a (−)-nicotine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a (−)-nicotine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a (−)-nicotine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }