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Research draft

plasma membrane

vr.tr.plasma-membrane · PHY.LIV

Let an agent explain the plasma membrane and its structure and functions, describe transport and signalling across it, describe specialised membranes and their roles in health and disease, and support learning in cell biology.

Thing Registry Physical world and living systems

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain the plasma membrane and its structure and functions, describe transport and signalling across it, describe specialised membranes and their roles in health and disease, and support learning in cell biology.

The membrane that separates the interior of a cell from its environment, composed of a phospholipid bilayer with embedded proteins, cholesterol and carbohydrates, regulating the passage of substances by passive transport such as diffusion and osmosis and by active transport, receiving signals through receptors, and taking specialised forms such as the sarcolemma of muscle cells, the sperm membrane and the outer membrane of some bacteria; the plasma membrane is fundamental to cell identity, communication and homeostasis.

What it is for: The boundary membrane of cells.

It can be explain structure and functions; describe transport and signalling; describe specialised forms; support learning.

Distinguishing features

Lipid bilayer

Selective permeability

Membrane proteins

Fluid mosaic

What it looks like

Not visible without a microscope; a thin bilayer.

How it is recognised

Phospholipid bilayer bounding the cell

Selective transport, receptors, specialised forms

The cell wall is a rigid outer layer in plants and bacteria; organelle membranes are internal

Related models

is a kind of - category

membrane

is related to - an organelle with its own membranes

mitochondrion

is related to - uptake across membranes

absorption

is related to - B-cell receptors on the membrane

antibody

In practice

Families and kinds

plasma membranes of animal cells

plasma membranes of plant and fungal cells

bacterial inner and outer membranes

specialised membranes such as the sarcolemma

membrane domains and rafts

Standards and regulation

Cell biology nomenclature

Laboratory standards

No regulation of the concept

Failure modes and hazards

Oversimplified membrane models

Confusing membrane with cell wall

Agents giving personal medical advice

Also called

passive transportcornified envelopesarcolemmasperm plasma membranebacterial outer membraneplasma membrane of muscle cellplasma membrane of mature erythrocyteplasma membrane of epithelial cellPlasma membrane of hemal cellPlasma membrane of connective tissue cellPlasma membrane of stem cellPlasma membrane of diploid germ cellPlasma membrane of neural cellPlasma membrane of erythrocyteintracellular membranespurple membrane

Where this came from

wikidata · CC0 1.0

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand What the plasma membrane is.

Cell biology.

Structure

Structure.

Structure

Structure.

  1. What is the structure of the plasma membrane, and what does the fluid mosaic model describe? definition
  2. Which cell type or aspect is meant? boundary

Transport

Transport.

Transport

Transport.

  1. How do passive transport, active transport, channels, carriers and vesicles move substances across the membrane? definition
  2. Which entry fits membrane transport? action
Function Functions and specialisations.

Science.

Signalling

Signalling and identity.

Signalling

Signalling.

  1. How do receptors and surface molecules enable signalling, adhesion and immune recognition? provenance
  2. Which entry fits cell signalling? action

Specialised

Specialised membranes.

Specialised

Specialised.

  1. How do the sarcolemma, sperm membrane and bacterial outer membrane differ from a generic plasma membrane? provenance
  2. Which entry fits a specific membrane? action
Health Health and applications.

General information.

Disease

Membranes in disease.

Disease

Disease.

  1. How do membrane defects and membrane-targeting drugs relate to disease and treatment, in general terms? provenance
  2. Is the user asking about their own condition, which needs a clinician? boundary

Research

Research methods.

Research

Research.

  1. How are membranes studied with microscopy, biophysics and molecular methods? provenance
  2. Which findings are contested? boundary
Learn History and teaching.

Education.

History

History.

History

History.

  1. How did membrane models develop from early bilayer proposals to the fluid mosaic model? provenance
  2. Which references are standard? provenance

Teach

Teaching.

Teach

Teaching.

  1. How can the plasma membrane be taught with models? action
  2. Which misconceptions arise? provenance

What the second pass must settle

  • Should membrane transport be a separate entry?
  • How should cell biology resources be linked?
  • How should research literature be linked?