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Research draft

biological process

vr.tr.biological-process · ACT.PRC

Let an agent handle biological processes as the general concept, routing to specific processes and linking to ontologies such as the Gene Ontology.

Thing Registry Activities and processes

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent handle biological processes as the general concept, routing to specific processes and linking to ontologies such as the Gene Ontology.

Any process carried out by living organisms or their parts, such as metabolism, growth, reproduction, digestion, reflexes and cell signalling, as the general concept for biological processes.

What it is for: The entry above specific biological processes.

It can be classify a process; link to Gene Ontology terms; describe steps and regulation; find evidence for mechanisms.

Distinguishing features

Carried out by living systems

Levels from molecules to organisms

Regulated

Catalogued in ontologies

What it looks like

Not a single appearance; processes inside organisms and cells.

How it is recognised

Named processes such as digestion or reflex

GO biological process terms

Specific processes are separate entries

Related models

is a kind of - category

physical process

has kind - kinds

digestion, reflex, learning

is catalogued in - ontology

Gene Ontology

is studied by - field

biology

In practice

Families and kinds

metabolic processes

developmental processes

reproductive processes

signalling and regulation

organismal processes such as digestion

Identifiers

GO id GO:0008150 biological process root

Standards and regulation

Gene Ontology guidelines

Failure modes and hazards

Overstating mechanisms

Mixing levels of organisation

Where this came from

wikidata · CC0 1.0

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Kind Which process.

Kind leads to specific entries.

Type

Metabolic, developmental.

Type

Process type.

  1. Which biological process is meant? definition
  2. Which specific entry fits? action

Level

Molecule to organism.

Level

Level.

  1. At which level does it occur? definition
  2. In which organisms? definition
Mechanism How it works.

Mechanisms need evidence.

Steps

Sequence.

Steps

Steps.

  1. What are its main steps? definition
  2. How is it regulated? definition

Evidence

Studies.

Evidence

Evidence.

  1. What evidence supports the mechanism? provenance
  2. Which GO evidence codes apply? provenance
Ontology Terms.

Ontologies standardise.

GO term

Identifier.

GO

GO term.

  1. Which GO term matches it? provenance
  2. Where does it sit in the hierarchy? definition

Annotation

Genes.

Annotation

Gene annotation.

  1. Which genes are annotated to it? provenance
  2. In which species? definition
Health When it fails.

Disrupted processes cause disease.

Disease

Dysfunction.

Disease

Dysfunction.

  1. Which diseases involve disruption of this process? provenance
  2. Is this general information only? boundary

Research

Open questions.

Research

Research.

  1. What remains unknown? provenance
  2. Which reviews summarise it? provenance

What the second pass must settle

  • How should the general entry organise children?
  • How should GO terms be linked?
  • How should evidence codes be recorded?