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Research draft

leprosy

vr.tr.leprosy · INF.KNW

Let an agent explain leprosy in general terms from WHO and clinical sources, relay classification, treatment and prevention, present history and stigma with attribution, and route personal medical questions to clinicians.

Thing Registry Information and virtual systems

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain leprosy in general terms from WHO and clinical sources, relay classification, treatment and prevention, present history and stigma with attribution, and route personal medical questions to clinicians.

A chronic infectious disease caused by Mycobacterium leprae and Mycobacterium lepromatosis, affecting the skin, peripheral nerves, upper respiratory tract and eyes, classified as paucibacillary or multibacillary and across a spectrum from tuberculoid to borderline and lepromatous forms, with immune reactions such as erythema nodosum leprosum; leprosy, also called Hansen disease, is curable with multidrug therapy, is transmitted only with prolonged close contact, and has a long history of stigma and segregation.

What it is for: Not applicable; a disease.

It can be explain the disease and classification; relay treatment and prevention; present history and stigma; route personal questions to clinicians.

Distinguishing features

Slow-growing bacterium

Nerve damage and disability

Curable with multidrug therapy

Historical stigma

What it looks like

Not a visible object; a clinical illness with skin lesions and nerve damage.

Physical character

new cases per year: about 180000 people - WHO, recent years

incubation: about 5 years - average, up to 20

How it is recognised

Chronic mycobacterial disease of skin and nerves

Paucibacillary, multibacillary, tuberculoid, borderline, lepromatous

Biblical and historical uses of leprosy covered various skin conditions; alphos was a historical term

Related models

is a kind of - in registry terms

primary bacterial infectious disease

is caused by - and M. lepromatosis

Mycobacterium leprae

is treated with - rifampicin, dapsone and clofazimine

multidrug therapy

is a - per WHO

neglected tropical disease

In practice

Families and kinds

paucibacillary and multibacillary leprosy

tuberculoid, borderline and lepromatous forms

leprosy reactions including erythema nodosum leprosum

leprosy caused by Mycobacterium lepromatosis

historical terms such as alphos

Identifiers

ICD-11 1B20

MeSH D007918

Standards and regulation

WHO leprosy guidelines and global strategy

National elimination programmes

UN principles on eliminating discrimination against persons affected by leprosy

Failure modes and hazards

Stigma and discriminatory language

Delayed diagnosis and disability

Agents giving personal medical advice

Confusing historical and modern uses of the term

Also called

Erythema nodosum leprosumalphosborderline leprosypaucibacillary leprosymultibacillary leprosylepromatous leprosyLucio's phenomenon

Where this came from

wikidata · CC0 1.0

Also registered as vr.tr.leprosy

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand The disease.

Clinical.

Definition

Definition and classification.

Definition

Definition.

  1. What is leprosy, and how is it classified? definition
  2. Is the question about the modern disease or historical uses of the term? boundary

Illness

Symptoms and transmission.

Illness

Illness.

  1. What are the signs, and how is leprosy transmitted, in general terms? definition
  2. Is the user describing personal symptoms, which need a clinician? boundary
Care Treatment and prevention.

Public health.

Treatment

Treatment.

Treatment

Treatment.

  1. How is leprosy treated with multidrug therapy, and how are reactions managed, per guidelines? provenance
  2. Which references are standard? provenance

Prevention

Prevention and elimination.

Prevention

Prevention.

  1. What prevention measures and elimination strategies exist, including post-exposure prophylaxis? provenance
  2. Which entry fits neglected tropical diseases? action
Where Epidemiology.

Sources.

Distribution

Distribution.

Distribution

Distribution.

  1. Where does leprosy occur today, and what are the case numbers, from WHO? measurement
  2. Which sources are cited? provenance

Disability

Disability and rehabilitation.

Disability

Disability.

  1. How is leprosy-related disability prevented and rehabilitated? provenance
  2. Which entry fits rehabilitation? action
History History and stigma.

Attribution.

History

History.

History

History.

  1. How has leprosy been understood and treated historically, including leprosaria and Hansen discovery? provenance
  2. Which entry fits the history of medicine? action

Stigma

Stigma and rights.

Stigma

Stigma.

  1. How have stigma and discrimination affected people with leprosy, and what rights frameworks exist, with attribution? provenance
  2. Is the language respectful and person-first? boundary

What the second pass must settle

  • Should leprosy reactions be a separate entry?
  • How should WHO guidance be linked?
  • The registry entry has merged aliases naming forms and a historical term; should they be split off?