{ "model": { "rank": 5732, "code": "thing-q483745", "model_id": "vr.tr.l-leucine", "name": "L-leucine", "purpose": "Enable an AI agent to identify L-leucine, assess the identity and condition of a material containing it, and determine whether that material is suitable for a specified operation.", "family": "Thing Registry", "category": "Physical world and living systems", "status": "research-draft", "kind": "thing", "plane": "PHY", "domain": "PHY.MAT", "industry": "", "version": "", "url": "/models/thing/q483745/", "tier": 2, "score": 65, "payload": { "layer": "wikidata", "aliases": [], "aliasCount": 0, "merged": 0, "knownIn": 65, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q483745", "url": "https://www.wikidata.org/wiki/Q483745", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-07T09:08:59Z", "providers": [ "Codex" ], "missingProviders": [ "Grok" ], "pass": 2, "cost": { "grok": { "usd": null, "turns": null, "seconds": 10.5, "error": "Error: Internal error: {\n \"message\": \"API error (status 402 Payment Required): Grok Build usage balance exhausted\",\n \"http_status\": 402\n}", "retried": true }, "codex": { "seconds": 93.5, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.3\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a07b1f-542c-7703-8d4b-71aaf55e1fae\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: L-leucine\nRegistry id: vr.tr.l-leucine\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\nA Ver" } } }, "metaModel": { "id": "THING-Q483745", "registryId": "vr.tr.l-leucine", "name": "L-leucine", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q483745/", "model": { "registry_id": "vr.tr.l-leucine", "name": "L-leucine", "purpose": "Enable an AI agent to identify L-leucine, assess the identity and condition of a material containing it, and determine whether that material is suitable for a specified operation.", "definition": "", "scope_statement": "This model owns the chemical identity of L-leucine (vr.tr.l-leucine, PHY / PHY.MAT), its occurrence as free material or a measured constituent, and the evidence needed to assess its amount, purity, physical state and use suitability; protonation states are contextual representations, while salts, derivatives and peptide-bound residues require explicit relationships.", "in_scope": [ "L-leucine molecular connectivity and stereochemical identity", "Free L-leucine in powders, solutions and mixtures", "L-leucine assay, enantiomeric composition and relevant impurities", "Physical condition, dissolution behaviour and preparation history", "Evidence supporting material acceptance for a specified use" ], "out_of_scope": [ "D-leucine and isoleucine as independently identified substances", "Peptide and protein sequence models containing leucine residues", "Complete models of leucine salts, protected derivatives and reaction products", "Finished supplement, food and pharmaceutical formulation models", "Patient nutrition, dosing, disease management and clinical benefit", "Organism-level leucine metabolism and signalling networks" ], "distinguishing_features": [ "Require connectivity consistent with 2-amino-4-methylpentanoic acid and the L configuration, corresponding to the 2S stereocentre; an unqualified leucine label does not establish stereochemistry. [ChEBI L-leucine](https://www.ebi.ac.uk/chebi/CHEBI%3A15603)", "Distinguish L-leucine from D-leucine and DL-leucine using evidence capable of resolving enantiomers; molecular formula or an achiral identity test alone is insufficient.", "Distinguish leucine from isoleucine through side-chain connectivity: leucine has an isobutyl side chain, whereas isoleucine has a sec-butyl side chain; require a method demonstrated to distinguish them. [ChEBI L-isoleucine](https://www.ebi.ac.uk/chebi/CHEBI%3A17191)", "Distinguish free L-leucine from a leucine residue released by protein or peptide hydrolysis by recording covalent context and sample preparation. [ChEBI L-leucine](https://www.ebi.ac.uk/chebi/CHEBI%3A15603)", "Recognise the zwitterionic representation as related to L-leucine identity, while separately recording protonation and any counterions rather than treating every charged representation as a different ingredient. [ChEBI L-leucine zwitterion](https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI%3A57427)" ], "characteristics": [ { "name": "Connectivity and absolute configuration", "kind": "category", "unit_or_values": "Structure identifier with explicit stereochemistry; confirmed L-leucine, conflicting identity or unresolved", "why_it_matters": "Prevents substitution by an enantiomer or a constitutional isomer." }, { "name": "Chemical presentation", "kind": "category", "unit_or_values": "Free amino acid, protonated or deprotonated species, salt-associated constituent, covalently bound residue or unresolved", "why_it_matters": "Determines whether this model directly describes the material or only a constituent relationship." }, { "name": "L-leucine content", "kind": "measurement", "unit_or_values": "Mass fraction %, mg/g, mol/L or mmol/L, with assay method, uncertainty and reporting basis", "why_it_matters": "Supports quantity calculations without confusing total leucine with specifically measured L-leucine." }, { "name": "Enantiomeric composition", "kind": "measurement", "unit_or_values": "L and D fractions of total leucine, or enantiomeric excess %, with method and detection limits", "why_it_matters": "Establishes stereochemical quality independently of bulk chemical purity." }, { "name": "Related amino acid impurities", "kind": "measurement", "unit_or_values": "Individual impurity concentrations in mg/g or %, with identity confidence and quantification limits", "why_it_matters": "Reveals contamination or analytical overlap that could inflate the reported leucine result." }, { "name": "Water content", "kind": "measurement", "unit_or_values": "% mass fraction with water-specific method, or separately identified loss-on-drying result", "why_it_matters": "Affects weighed potency and prevents treating all drying loss as water." }, { "name": "Physical and dissolution state", "kind": "state", "unit_or_values": "Powder, crystalline solid, solution or suspension; fully dissolved, residual solid, precipitated or unassessed", "why_it_matters": "Determines whether a transferred portion delivers the intended amount uniformly." }, { "name": "Solution conditions", "kind": "measurement", "unit_or_values": "pH, temperature in °C and solvent composition", "why_it_matters": "Provides the conditions needed to interpret protonation, solubility and preparation performance." }, { "name": "Batch evidence", "kind": "relation", "unit_or_values": "Links to supplier lot, sampled portion, certificate, analytical results and preparation history", "why_it_matters": "Connects a claim about L-leucine to the material actually being evaluated." }, { "name": "Use-specific disposition", "kind": "state", "unit_or_values": "Unassessed, accepted for named use, quarantined, rejected or awaiting retest", "why_it_matters": "Prevents acceptance for one purpose from becoming unrestricted permission for another." } ], "affordances": [ "Identify a candidate material using complementary connectivity and stereochemical evidence.", "Quantify L-leucine while separating free, total-after-hydrolysis and stereochemically unresolved results.", "Accept, quarantine or reject a batch against an explicit use-specific specification.", "Calculate a weighed amount or dilution using the applicable assay and moisture basis.", "Prepare and assess a solution or suspension under recorded conditions.", "Link incorporation into a formulation, peptide or reaction product to the appropriate neighbouring model." ] }, "sources": [], "structure": { "bundles": [ { "id": "leucine-identity-boundaries", "name": "Leucine identity and boundaries", "description": "Establish what qualifies as L-leucine and what must remain a related substance or constituent.", "rationale": "A leucine name or formula alone cannot resolve stereochemistry, isomerism or covalent context.", "layers": [ { "id": "connectivity-and-chirality", "name": "Connectivity and chirality", "description": "Assess independent evidence for the leucine skeleton and L configuration.", "findings": [ { "id": "confirmed-l-leucine-identity", "name": "Confirmed L-leucine identity", "description": "Record the proposed identity, supporting observations and unresolved alternatives without upgrading a supplier label into analytical confirmation.", "questions": [ { "text": "What evidence establishes leucine connectivity and excludes isoleucine or other potentially confusable amino acids?", "kind": "definition", "id": "confirmed-l-leucine-identity-q01" }, { "text": "What stereoselective evidence establishes the L configuration and constrains D-leucine content?", "kind": "measurement", "id": "confirmed-l-leucine-identity-q02" } ] } ] }, { "id": "free-bound-and-ionic-context", "name": "Free, bound and ionic context", "description": "Separate protonation context from salts, covalent derivatives and leucine residues.", "findings": [ { "id": "chemical-context-assignment", "name": "Chemical context assignment", "description": "Record whether the observation concerns free L-leucine, a related ionic species or leucine obtained from another material.", "questions": [ { "text": "Was L-leucine present freely in the original material, or was it released or chemically altered during preparation?", "kind": "boundary", "id": "chemical-context-assignment-q01" }, { "text": "Which protonation conditions, counterions or covalent attachments require a relationship to a neighbouring substance model?", "kind": "boundary", "id": "chemical-context-assignment-q02" } ] } ] } ] }, { "id": "leucine-assay-and-selectivity", "name": "Leucine assay and selectivity", "description": "Determine how much L-leucine is present and whether the measurement actually resolves it.", "rationale": "A total amino acid result or unresolved leucine signal cannot automatically support an L-leucine quantity.", "layers": [ { "id": "measurand-and-reporting-basis", "name": "Measurand and reporting basis", "description": "Define the material fraction and chemical quantity represented by an assay.", "findings": [ { "id": "interpretable-leucine-quantity", "name": "Interpretable leucine quantity", "description": "Attach every amount to its sample, analytical target, units and moisture or preparation basis.", "questions": [ { "text": "Does the result measure free L-leucine, unresolved D-plus-L leucine or total leucine after hydrolysis?", "kind": "definition", "id": "interpretable-leucine-quantity-q01" }, { "text": "What amount is reported, with what uncertainty, and on an as-received, dry-mass or solution-volume basis?", "kind": "measurement", "id": "interpretable-leucine-quantity-q02" } ] } ] }, { "id": "interferences-and-reference-materials", "name": "Interferences and reference materials", "description": "Assess whether the analytical method and calibration support the claimed specificity.", "findings": [ { "id": "assay-specificity-evidence", "name": "Assay specificity evidence", "description": "Record demonstrated separation or discrimination, calibration provenance and limitations relevant to leucine.", "questions": [ { "text": "Can this method distinguish leucine from isoleucine and distinguish its enantiomers, and which unresolved components remain?", "kind": "measurement", "id": "assay-specificity-evidence-q01" }, { "text": "Which reference material, calibration and sample-preparation records support the reported L-leucine result?", "kind": "provenance", "id": "assay-specificity-evidence-q02" } ] } ] } ] }, { "id": "leucine-batch-composition", "name": "Leucine batch composition", "description": "Assess the actual batch beyond its nominal L-leucine identity.", "rationale": "Stereochemical purity, related amino acids and process-dependent contaminants can impose different acceptance limits.", "layers": [ { "id": "enantiomers-and-related-amino-acids", "name": "Enantiomers and related amino acids", "description": "Separate L-leucine content from D-leucine and other amino acid components.", "findings": [ { "id": "resolved-amino-acid-composition", "name": "Resolved amino acid composition", "description": "Maintain distinct observations for chemical assay, enantiomeric composition and related amino acid impurities.", "questions": [ { "text": "What D-leucine fraction is measured or bounded, and what denominator defines the reported enantiomeric purity?", "kind": "measurement", "id": "resolved-amino-acid-composition-q01" }, { "text": "Which related amino acids are detected, and could any have been counted in the L-leucine assay?", "kind": "measurement", "id": "resolved-amino-acid-composition-q02" } ] } ] }, { "id": "production-linked-quality", "name": "Production-linked quality", "description": "Connect manufacturing and handling evidence to the impurity assessment required for the intended use.", "findings": [ { "id": "batch-quality-evidence", "name": "Batch quality evidence", "description": "Record the known production route and relevant water, residual-process-material and contamination results without inferring them from a grade label.", "questions": [ { "text": "What production route and lot-specific evidence establish which contaminants require assessment?", "kind": "provenance", "id": "batch-quality-evidence-q01" }, { "text": "Which water, residual solvent, inorganic or microbiological limits apply to the intended use, and which results remain missing?", "kind": "boundary", "id": "batch-quality-evidence-q02" } ] } ] } ] }, { "id": "leucine-physical-preparation", "name": "Leucine physical preparation", "description": "Describe the material state and conditions needed to obtain a usable L-leucine preparation.", "rationale": "Correct chemical identity does not establish that a powder transfers reproducibly or that a nominal solution is fully dissolved.", "layers": [ { "id": "solid-condition-and-weighing", "name": "Solid condition and weighing", "description": "Assess powder condition and the basis for converting weighed material into L-leucine amount.", "findings": [ { "id": "weighable-leucine-material", "name": "Weighable leucine material", "description": "Record physical changes and assay corrections relevant to obtaining a representative portion.", "questions": [ { "text": "Is the powder homogeneous and transferable, or do clumping, segregation or other observed changes require investigation?", "kind": "measurement", "id": "weighable-leucine-material-q01" }, { "text": "What assay and moisture correction, if any, converts the proposed weighed mass into the required L-leucine amount?", "kind": "action", "id": "weighable-leucine-material-q02" } ] } ] }, { "id": "dissolution-and-solution-state", "name": "Dissolution and solution state", "description": "Record solvent conditions and evidence that the target preparation has been achieved.", "findings": [ { "id": "verified-leucine-preparation", "name": "Verified leucine preparation", "description": "Distinguish intended concentration from achieved dissolved concentration and track precipitation or residual solid.", "questions": [ { "text": "At the recorded solvent composition, pH and temperature, what evidence shows that the intended L-leucine amount has dissolved?", "kind": "measurement", "id": "verified-leucine-preparation-q01" }, { "text": "If solid remains or appears later, should the preparation be mixed as a suspension, adjusted under an approved procedure or rejected for its intended use?", "kind": "action", "id": "verified-leucine-preparation-q02" } ] } ] } ] }, { "id": "leucine-use-and-disposition", "name": "Leucine use and disposition", "description": "Translate identity, composition and condition evidence into bounded material decisions.", "rationale": "L-leucine intended for an analytical reference, synthesis, culture medium or ingredient requires different evidence.", "layers": [ { "id": "use-specific-acceptance", "name": "Use-specific acceptance", "description": "Tie material acceptance to a named operation and its governing specification.", "findings": [ { "id": "supported-use-decision", "name": "Supported use decision", "description": "Record which proposed use is supported and which missing evidence prevents acceptance.", "questions": [ { "text": "What named operation and specification determine the required L-leucine identity, purity, concentration and contaminant limits?", "kind": "boundary", "id": "supported-use-decision-q01" }, { "text": "Do the available results justify acceptance, quarantine, further testing or rejection for that operation?", "kind": "action", "id": "supported-use-decision-q02" } ] } ] }, { "id": "condition-history-and-transformations", "name": "Condition history and transformations", "description": "Track events that could invalidate a prior assessment or move the material into another model.", "findings": [ { "id": "reassessment-and-model-handoff", "name": "Reassessment and model handoff", "description": "Relate storage and preparation history to reassessment, and link deliberate chemical transformation to the resulting substance.", "questions": [ { "text": "What storage excursions, container changes, preparation events or elapsed intervals trigger reassessment under the applicable stability evidence?", "kind": "action", "id": "reassessment-and-model-handoff-q01" }, { "text": "If L-leucine is derivatised, incorporated into a peptide or otherwise reacted, what resulting entity takes ownership of its new identity and state?", "kind": "boundary", "id": "reassessment-and-model-handoff-q02" } ] } ] } ] } ] }, "openQuestions": [ "Which existing Vercy publications already cover L-leucine or its chemical-state representations, and should this registry entry link to one of them?", "Which current specifications and acceptance limits apply to each intended grade and use of L-leucine?", "Which analytical methods demonstrate adequate leucine/isoleucine discrimination and D/L resolution in the matrices this model must support?", "What condition-specific solubility, solid-form and stability evidence supports preparation limits, storage requirements and retest intervals?", "Should isotopically enriched L-leucine remain a qualified instance of this entry or link to a separately registered tracer model?" ], "statistics": { "bundles": 5, "layers": 10, "findings": 10, "questions": 20 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "chemical substance or material", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a L-leucine, record what state it is in, and decide what may be done with it.", "whatItIs": "Enable an AI agent to identify L-leucine, assess the identity and condition of a material containing it, and determine whether that material is suitable for a specified operation.", "characteristics": { "substance": "material", "origin": "natural", "agency": "inert", "mobility": "varies" }, "whatYouCanDoWithIt": [ "observed and measured", "consumed or used up" ], "distinguishingFeatures": [ "Described in 65 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a L-leucine, and on what evidence are they told apart?" ], "whatItIsMadeOf": "matter you can touch", "physicalCharacter": [ "Mobility varies between examples.", "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state", "use it up, and then need more of it" ], "howItIsRecognised": [ "Not recognisable by sight in any reliable way. Appearance varies with grade, form and additives; identification is by label, by documentation, or by assay." ], "relatedModels": [], "standing": "Described in 65 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one L-leucine from another, and a L-leucine from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a L-leucine sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a L-leucine from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "form-and-composition", "name": "Form, composition and condition", "description": "What a L-leucine is made of, what shape and size it takes, and what state it is in.", "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.", "layers": [ { "id": "form-and-dimensions", "name": "Form and dimensions", "description": "Shape, size, mass and the ranges these take across examples.", "findings": [ { "id": "measurable-dimensions", "name": "Measurable dimensions and their units", "description": "The quantities worth recording and the units they are recorded in.", "questions": [ { "id": "measurable-dimensions-q01", "text": "What identifies and describes the dimensions of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "measurable-dimensions-q02", "text": "Who or what asserted this about the dimensions of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "measurable-dimensions-q03", "text": "What may an agent decide or do once the dimensions of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "material-and-composition", "name": "Material and composition", "description": "Materials, parts and how they are put together.", "findings": [ { "id": "parts-and-materials", "name": "Parts and materials", "description": "What a L-leucine is built from and which parts are replaceable.", "questions": [ { "id": "parts-and-materials-q01", "text": "What identifies and describes the composition of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "parts-and-materials-q02", "text": "Who or what asserted this about the composition of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "parts-and-materials-q03", "text": "What may an agent decide or do once the composition of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "condition-and-integrity", "name": "Condition and integrity", "description": "Wear, damage, health and the difference between working and broken.", "findings": [ { "id": "condition-assessment", "name": "Condition, damage and health", "description": "How the condition of a L-leucine is judged and by whom.", "questions": [ { "id": "condition-assessment-q01", "text": "What identifies and describes the condition of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "condition-assessment-q02", "text": "Who or what asserted this about the condition of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "condition-assessment-q03", "text": "What may an agent decide or do once the condition of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "place-and-movement", "name": "Place and movement", "description": "Where a L-leucine is, how it got there and where it may go (varies).", "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.", "layers": [ { "id": "location-and-placement", "name": "Location and placement", "description": "Position, containment and the reference frame the position is given in.", "findings": [ { "id": "position-and-frame", "name": "Position, container and reference frame", "description": "Where a L-leucine is, and what that position is measured against.", "questions": [ { "id": "position-and-frame-q01", "text": "What identifies and describes the location of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "position-and-frame-q02", "text": "Who or what asserted this about the location of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "position-and-frame-q03", "text": "What may an agent decide or do once the location of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "movement-and-transfer", "name": "Movement and transfer", "description": "How a L-leucine is carried, installed or relocated.", "findings": [ { "id": "movement-events", "name": "Movement events and constraints", "description": "What counts as a movement, what records it and what limits it.", "questions": [ { "id": "movement-events-q01", "text": "What identifies and describes the movement of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "movement-events-q02", "text": "Who or what asserted this about the movement of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "movement-events-q03", "text": "What may an agent decide or do once the movement of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a L-leucine passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a L-leucine between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a L-leucine, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a L-leucine is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "use-and-operation", "name": "Use and operation", "description": "What can be done with a L-leucine and what it takes to do it.", "rationale": "An agent that can recognise a thing but not act on it has only half a model.", "layers": [ { "id": "intended-use", "name": "Intended use and function", "description": "What a L-leucine is for, and what it is used for anyway.", "findings": [ { "id": "function-and-purpose", "name": "Function, purpose and misuse", "description": "The function a L-leucine performs and the uses that fall outside it.", "questions": [ { "id": "function-and-purpose-q01", "text": "What identifies and describes the use of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "function-and-purpose-q02", "text": "Who or what asserted this about the use of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "function-and-purpose-q03", "text": "What may an agent decide or do once the use of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "handling-and-procedure", "name": "Handling and procedure", "description": "The steps, skills and tools involved in using a L-leucine.", "findings": [ { "id": "procedures-and-skills", "name": "Procedures, skills and required tools", "description": "What an agent needs before it can act on a L-leucine at all.", "questions": [ { "id": "procedures-and-skills-q01", "text": "What identifies and describes handling a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "procedures-and-skills-q02", "text": "Who or what asserted this about handling a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "procedures-and-skills-q03", "text": "What may an agent decide or do once handling a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "supply-and-consumption", "name": "Supply and consumption", "description": "Quantities, rates and what running out means.", "findings": [ { "id": "consumption-and-stock", "name": "Consumption, stock and replenishment", "description": "How much of a L-leucine there is and how fast it goes.", "questions": [ { "id": "consumption-and-stock-q01", "text": "What identifies and describes the supply of a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "consumption-and-stock-q02", "text": "Who or what asserted this about the supply of a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "consumption-and-stock-q03", "text": "What may an agent decide or do once the supply of a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "composition-and-identity", "name": "Composition, grade and chemical identity", "description": "What L-leucine is made of and how pure the thing in hand is.", "rationale": "Grade decides what a substance may be used for, so a model that records only the name cannot support any decision about use.", "layers": [ { "id": "chemical-identity", "name": "Chemical identity", "description": "Formula, structure and the registry numbers that name it unambiguously.", "findings": [ { "id": "identity-record", "name": "Identity and registry numbers", "description": "What identifies this substance across suppliers and regulators.", "questions": [ { "id": "identity-record-q01", "text": "What formula, structure and registry identifiers name L-leucine unambiguously?", "kind": "definition" }, { "id": "identity-record-q02", "text": "Which related substances share a name in common use but not an identifier?", "kind": "boundary" } ] } ] }, { "id": "grade-and-impurities", "name": "Grade, purity and impurities", "description": "The specification a batch meets and what else is in it.", "findings": [ { "id": "specification", "name": "Specification and assay", "description": "How purity is stated and measured, and which impurities matter.", "questions": [ { "id": "specification-q01", "text": "What grades of L-leucine exist, how is purity assayed, and which impurities are limited?", "kind": "measurement" }, { "id": "specification-q02", "text": "Which use requires which grade, and what happens when a lower grade is substituted?", "kind": "action" } ] } ] } ] }, { "id": "properties-and-behaviour", "name": "Properties and behaviour", "description": "How L-leucine behaves under conditions an agent can measure or change.", "rationale": "Physical constants are the part of a substance model that transfers between contexts, and each needs its unit and its conditions.", "layers": [ { "id": "physical-constants", "name": "Physical constants", "description": "Values that hold for the pure substance, with their conditions.", "findings": [ { "id": "constants-record", "name": "Constants and conditions", "description": "The quantities worth recording and the state they apply in.", "questions": [ { "id": "constants-record-q01", "text": "What are the defining physical constants of L-leucine, in what units and under what conditions?", "kind": "measurement" }, { "id": "constants-record-q02", "text": "Which of these values change with grade or form rather than being fixed?", "kind": "boundary" } ] } ] }, { "id": "stability-and-reactivity", "name": "Stability and reactivity", "description": "What it reacts with, degrades into, and how it is stored.", "findings": [ { "id": "incompatibilities", "name": "Incompatibilities and degradation", "description": "What must not meet it, and what it becomes over time.", "questions": [ { "id": "incompatibilities-q01", "text": "What is L-leucine incompatible with, and what does it degrade into under storage?", "kind": "definition" }, { "id": "incompatibilities-q02", "text": "What storage and handling does that require, and who is competent to do it?", "kind": "action" } ] } ] } ] }, { "id": "hazard-and-regulation", "name": "Hazard classification and regulation", "description": "How L-leucine can harm, and what the law says about holding and moving it.", "rationale": "A substance model without its hazard class and its regulatory identity is unusable in exactly the situations that matter.", "layers": [ { "id": "hazard-class", "name": "Hazard classification", "description": "Classified hazards, exposure limits and protective measures.", "findings": [ { "id": "classified-hazards", "name": "Classified hazards and limits", "description": "The classification, the scheme it belongs to, and the limits set.", "questions": [ { "id": "classified-hazards-q01", "text": "How is L-leucine classified for hazard, under which scheme, and what exposure limits apply?", "kind": "definition" }, { "id": "classified-hazards-q02", "text": "What protection does handling require, and what must an agent refuse to do without it?", "kind": "action" } ] } ] }, { "id": "regulatory-identity", "name": "Regulatory identity and control", "description": "Registration, restriction and transport rules by jurisdiction.", "findings": [ { "id": "controls", "name": "Controls and jurisdiction", "description": "Where it is restricted and what the restriction attaches to.", "questions": [ { "id": "controls-q01", "text": "Which registrations, restrictions or transport rules cover L-leucine, and where?", "kind": "provenance" }, { "id": "controls-q02", "text": "Does the control attach to the substance, its concentration, or its intended use?", "kind": "boundary" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a L-leucine came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a L-leucine and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a L-leucine is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a L-leucine, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a L-leucine, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a L-leucine is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 9, "layers": 20, "findings": 22, "questions": 60 } } } }