{ "model": { "rank": 10119, "code": "thing-q504775", "model_id": "vr.tr.bladder-cancer", "name": "bladder cancer", "purpose": "Let an agent explain bladder cancer and its types in general terms from urology and oncology guidelines, describe risk factors, symptoms, diagnosis and treatment approaches, and route personal questions to clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q504775/", "tier": 2, "score": 45, "payload": { "layer": "wikidata", "aliases": [ "bladder papillary transitional cell neoplasm", "bladder flat intraepithelial lesion", "bladder urachal carcinoma", "bladder inflammatory myofibroblastic tumor", "bladder lateral wall cancer", "bladder neck cancer", "urinary bladder posterior wall cancer", "urinary bladder anterior wall cancer", "bladder dome cancer", "bladder lymphoma", "recurrent malignant bladder neoplasm", "urachal cancer", "bladder urachal squamous cell carcinoma", "bladder urachal urothelial carcinoma" ], "aliasCount": 14, "merged": 14, "knownIn": 45, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q504775", "url": "https://www.wikidata.org/wiki/Q504775", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-13T02:25:37Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude" }, "metaModel": { "id": "THING-Q504775", "registryId": "vr.tr.bladder-cancer", "name": "bladder cancer", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q504775/", "model": { "registry_id": "vr.tr.bladder-cancer", "name": "bladder cancer", "purpose": "Let an agent explain bladder cancer and its types in general terms from urology and oncology guidelines, describe risk factors, symptoms, diagnosis and treatment approaches, and route personal questions to clinicians.", "definition": "Cancer arising in the urinary bladder, chiefly urothelial carcinoma in papillary and flat forms including flat intraepithelial lesions, ranging from non-muscle-invasive tumours managed by resection and intravesical therapy to muscle-invasive disease requiring cystectomy or chemoradiation, with rarer types such as urachal carcinoma, squamous and small cell carcinomas and inflammatory myofibroblastic tumours, and sites such as the lateral wall and bladder neck; smoking and occupational chemicals are major risk factors, and blood in the urine is the main warning sign.", "what_it_is_for": "Not applicable; a cancer.", "affordances": [ "explain types and risk factors", "relay symptoms and diagnosis", "relay treatment approaches", "route personal questions" ], "distinguishing_features": [ "Urothelial origin", "Smoking as main risk", "High recurrence", "Stage-dependent treatment" ], "appearance": "Not a visible object; tumours seen at cystoscopy.", "visual_identification": [ "Malignant tumour of the bladder", "Urothelial carcinoma, papillary and flat lesions, rare types, sites", "Benign bladder tumours and papillomas are not cancer; kidney and prostate cancers are separate" ], "physical_properties": [ { "quantity": "new cases worldwide", "typical_range": "about 610000", "unit": "per year", "note": "GLOBOCAN 2022" }, { "quantity": "non-muscle-invasive share", "typical_range": "about 75", "unit": "percent", "note": "at diagnosis" } ], "families_and_kinds": [ "non-muscle-invasive urothelial carcinoma including papillary tumours and carcinoma in situ", "muscle-invasive urothelial carcinoma", "urachal carcinoma", "squamous cell and small cell carcinoma of the bladder", "rare tumours such as inflammatory myofibroblastic tumour", "cancers by site such as lateral wall and bladder neck" ], "related_models": [ { "relation": "is a kind of", "target": "bladder neoplasm", "why": "in registry terms" }, { "relation": "is a kind of", "target": "urinary system cancer", "why": "in registry terms" }, { "relation": "is diagnosed by", "target": "cystoscopy", "why": "with biopsy" }, { "relation": "is caused by", "target": "tobacco smoking", "why": "as the main risk factor" } ], "identifiers": [ { "scheme": "ICD-11", "value_or_pattern": "2C94", "note": "malignant neoplasms of bladder" }, { "scheme": "MeSH", "value_or_pattern": "D001749", "note": "urinary bladder neoplasms" } ], "standards_and_regulation": [ "EAU, NCCN and other urology and oncology guidelines", "Occupational exposure rules for bladder carcinogens", "Cancer registration standards" ], "failure_modes_and_hazards": [ "Ignored haematuria", "Agents giving personal medical advice", "Recurrence without surveillance", "Confusing types and stages" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "help", "name": "Help", "description": "Getting help first.", "rationale": "Safety.", "layers": [ { "id": "signs", "name": "Signs", "description": "Warning signs.", "findings": [ { "id": "signs-finding", "name": "Signs", "description": "Signs.", "questions": [ { "text": "Why does blood in the urine need prompt assessment, and what other signs matter?", "kind": "action" }, { "text": "Is the user describing such signs, which need a clinician promptly?", "kind": "boundary" } ] } ] }, { "id": "care", "name": "Care", "description": "Specialist care.", "findings": [ { "id": "care-finding", "name": "Care", "description": "Care.", "questions": [ { "text": "How is bladder cancer diagnosed and staged by urologists, in general terms?", "kind": "provenance" }, { "text": "Is the user asking about their own diagnosis, which needs their care team?", "kind": "boundary" } ] } ] } ] }, { "id": "understand", "name": "Understand", "description": "The cancer.", "rationale": "Clinical.", "layers": [ { "id": "types", "name": "Types", "description": "Types and stages.", "findings": [ { "id": "types-finding", "name": "Types", "description": "Types.", "questions": [ { "text": "What types and stages of bladder cancer exist?", "kind": "definition" }, { "text": "Is the question about bladder cancer or another urinary cancer?", "kind": "boundary" } ] } ] }, { "id": "risk", "name": "Risk", "description": "Risk factors.", "findings": [ { "id": "risk-finding", "name": "Risk", "description": "Risk.", "questions": [ { "text": "What risk factors, including smoking and occupational exposures, does research identify?", "kind": "provenance" }, { "text": "Which entry fits the specific type?", "kind": "action" } ] } ] } ] }, { "id": "treat", "name": "Treat", "description": "Treatment.", "rationale": "Clinical.", "layers": [ { "id": "treatment", "name": "Treatment", "description": "Treatment.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "What treatments do guidelines recommend for non-muscle-invasive and muscle-invasive disease, in general terms?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "followup", "name": "Follow-up", "description": "Surveillance and living.", "findings": [ { "id": "followup-finding", "name": "Follow-up", "description": "Follow-up.", "questions": [ { "text": "How is recurrence monitored, and what support exists after cystectomy?", "kind": "provenance" }, { "text": "Which entry fits urinary diversion?", "kind": "action" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Prevention and research.", "rationale": "Context.", "layers": [ { "id": "prevention", "name": "Prevention", "description": "Prevention.", "findings": [ { "id": "prevention-finding", "name": "Prevention", "description": "Prevention.", "questions": [ { "text": "What prevention and occupational protections reduce bladder cancer, with sources?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] }, { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research is advancing immunotherapy, targeted therapy and biomarkers, with findings attributed?", "kind": "provenance" }, { "text": "Which entry fits oncology research?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should urothelial carcinoma be the primary linked entry?", "How should guidelines be linked?", "The registry entry has merged aliases naming lesions, rare tumours and sites; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a bladder cancer, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain bladder cancer and its types in general terms from urology and oncology guidelines, describe risk factors, symptoms, diagnosis and treatment approaches, and route personal questions to clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: bladder papillary transitional cell neoplasm, bladder flat intraepithelial lesion, bladder urachal carcinoma, bladder inflammatory myofibroblastic tumor, bladder lateral wall cancer, bladder neck cancer, urinary bladder posterior wall cancer, urinary bladder anterior wall cancer, bladder dome cancer, bladder lymphoma, recurrent malignant bladder neoplasm, urachal cancer.", "14 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 45 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a bladder cancer, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "bladder papillary transitional cell neoplasm", "bladder flat intraepithelial lesion", "bladder urachal carcinoma", "bladder inflammatory myofibroblastic tumor", "bladder lateral wall cancer", "bladder neck cancer", "urinary bladder posterior wall cancer", "urinary bladder anterior wall cancer", "bladder dome cancer", "bladder lymphoma", "recurrent malignant bladder neoplasm", "urachal cancer" ] } ], "standing": "Described in 45 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 14 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one bladder cancer from another, and a bladder cancer from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a bladder cancer sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a bladder cancer from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a bladder cancer passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a bladder cancer between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a bladder cancer, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a bladder cancer is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of bladder cancer a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define bladder cancer, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover bladder cancer, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How bladder cancer develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does bladder cancer typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for bladder cancer, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a bladder cancer came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a bladder cancer and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a bladder cancer is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a bladder cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a bladder cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a bladder cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }