{ "model": { "rank": 6005, "code": "thing-q623031", "model_id": "vr.tr.liver-cancer", "name": "liver cancer", "purpose": "Let an agent explain types, causes and risk factors of liver cancer, relay general information on prevention, screening, diagnosis and treatment from health bodies, support patients and families in understanding care, and route personal medical questions to clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q623031/", "tier": 2, "score": 63, "payload": { "layer": "wikidata", "aliases": [ "neurofibroma of gallbladder", "metastase of liver cancer", "childhood cancer of liver", "liver carcinoma", "hepatoblastoma", "liver sarcoma", "hepatic osteogenic sarcoma", "liver lymphoma", "adult primary liver cancer", "recurrent cancer of liver", "localized resectable adult primary liver cancer", "calcifying nested epithelial stromal tumor of the liver", "solitary necrotic nodule of the liver", "undifferentiated embryonal sarcoma of the liver", "rare epithelial tumor of liver and intrahepatic biliary tract", "mucinous cystic neoplasm of the liver", "mixed hepatoblastoma", "macrotrabecular hepatoblastoma", "recurrent hepatoblastoma", "resectable hepatoblastoma", "hepatoblastoma with pure fetal epithelial differentiation", "mixed hepatoblastoma with teratoid features", "hepatoblastoma with combined fetal epithelial differentiation" ], "aliasCount": 23, "merged": 23, "knownIn": 63, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": "vr.tr.liver-cancer", "source": { "dataset": "wikidata", "item": "Q623031", "url": "https://www.wikidata.org/wiki/Q623031", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T02:23:20Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 2, "engine": "claude" }, "metaModel": { "id": "THING-Q623031", "registryId": "vr.tr.liver-cancer", "name": "liver cancer", "version": "0.2.0-wave.2", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q623031/", "model": { "registry_id": "vr.tr.liver-cancer", "name": "liver cancer", "purpose": "Let an agent explain types, causes and risk factors of liver cancer, relay general information on prevention, screening, diagnosis and treatment from health bodies, support patients and families in understanding care, and route personal medical questions to clinicians.", "definition": "A malignant tumour arising in the liver, most commonly hepatocellular carcinoma from liver cells, together with cholangiocarcinoma from bile ducts, hepatoblastoma in children and rare liver sarcomas, distinguished from cancers that spread to the liver from elsewhere; liver cancer is strongly associated with chronic hepatitis B and C, cirrhosis, alcohol, fatty liver disease and aflatoxin, and is diagnosed, staged and treated under clinical guidelines with surgery, transplantation, local therapies and drugs.", "what_it_is_for": "Malignant tumours of the liver.", "affordances": [ "explain types and causes", "relay prevention and treatment information", "support understanding of care", "route personal questions" ], "distinguishing_features": [ "Primary liver origin", "Hepatitis and cirrhosis link", "Types by cell of origin", "Guideline-based care" ], "appearance": "Not physical as a concept; tumours seen on imaging and pathology.", "visual_identification": [ "Primary malignant liver tumour", "Hepatocellular carcinoma most common", "Liver metastases are cancers from elsewhere" ], "physical_properties": [], "families_and_kinds": [ "hepatocellular carcinoma", "cholangiocarcinoma", "hepatoblastoma", "liver sarcomas and rare tumours", "metastatic cancer in the liver as a distinct category" ], "related_models": [ { "relation": "is a kind of", "target": "liver neoplasm", "why": "category" }, { "relation": "is related to", "target": "adenoma", "why": "benign liver tumours" }, { "relation": "is related to", "target": "stomach cancer", "why": "another cancer entry" }, { "relation": "is related to", "target": "epithelium", "why": "tissue of origin" } ], "identifiers": [], "standards_and_regulation": [ "Clinical practice guidelines for liver cancer", "Hepatitis vaccination and screening programmes", "Cancer registration and reporting" ], "failure_modes_and_hazards": [ "Agents giving personal diagnostic or treatment advice", "Confusing primary and metastatic liver cancer", "Outdated treatment information" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What liver cancer is.", "rationale": "General information.", "layers": [ { "id": "types", "name": "Types", "description": "Types.", "findings": [ { "id": "types-finding", "name": "Types", "description": "Types.", "questions": [ { "text": "What types of primary liver cancer exist, and how do they differ from liver metastases?", "kind": "definition" }, { "text": "Is the user asking about their own diagnosis, which needs their care team?", "kind": "boundary" } ] } ] }, { "id": "causes", "name": "Causes", "description": "Causes and risk factors.", "findings": [ { "id": "causes-finding", "name": "Causes", "description": "Causes.", "questions": [ { "text": "What are the causes and risk factors, according to health bodies?", "kind": "provenance" }, { "text": "Which entry fits hepatitis or cirrhosis?", "kind": "action" } ] } ] } ] }, { "id": "prevent", "name": "Prevent", "description": "Prevention and screening.", "rationale": "Public health.", "layers": [ { "id": "prevent", "name": "Prevent", "description": "Prevention.", "findings": [ { "id": "prevent-finding", "name": "Prevent", "description": "Prevention.", "questions": [ { "text": "How can liver cancer risk be reduced through vaccination, hepatitis treatment and lifestyle, according to health bodies?", "kind": "provenance" }, { "text": "Which entry fits hepatitis B vaccination?", "kind": "action" } ] } ] }, { "id": "screen", "name": "Screen", "description": "Surveillance.", "findings": [ { "id": "screen-finding", "name": "Screen", "description": "Surveillance.", "questions": [ { "text": "Who is offered surveillance for liver cancer, and how is it done, according to guidelines?", "kind": "provenance" }, { "text": "Is urgent care needed now?", "kind": "boundary" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Diagnosis and treatment.", "rationale": "Guidelines.", "layers": [ { "id": "diagnose", "name": "Diagnose", "description": "Diagnosis and staging.", "findings": [ { "id": "diagnose-finding", "name": "Diagnose", "description": "Diagnosis.", "questions": [ { "text": "How is liver cancer diagnosed and staged, in general terms?", "kind": "provenance" }, { "text": "Which entry fits cancer staging?", "kind": "action" } ] } ] }, { "id": "treat", "name": "Treat", "description": "Treatment.", "findings": [ { "id": "treat-finding", "name": "Treat", "description": "Treatment.", "questions": [ { "text": "What treatments exist, from surgery and transplantation to local therapies and drugs, according to guidelines?", "kind": "provenance" }, { "text": "Which entry fits a specific treatment?", "kind": "action" } ] } ] } ] }, { "id": "learn", "name": "Learn", "description": "Epidemiology and research.", "rationale": "Education.", "layers": [ { "id": "epidemiology", "name": "Epidemiology", "description": "Epidemiology.", "findings": [ { "id": "epidemiology-finding", "name": "Epidemiology", "description": "Epidemiology.", "questions": [ { "text": "How common is liver cancer worldwide, and how does incidence vary by region?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research and trials are under way, and which findings are uncertain?", "kind": "provenance" }, { "text": "Which misconceptions arise?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should each type be a separate entry?", "How should guidelines be linked?", "How should support organisations be linked?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a liver cancer, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain types, causes and risk factors of liver cancer, relay general information on prevention, screening, diagnosis and treatment from health bodies, support patients and families in understanding care, and route personal medical questions to clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: neurofibroma of gallbladder, metastase of liver cancer, childhood cancer of liver, liver carcinoma, hepatoblastoma, liver sarcoma, hepatic osteogenic sarcoma, liver lymphoma, adult primary liver cancer, recurrent cancer of liver, localized resectable adult primary liver cancer, calcifying nested epithelial stromal tumor of the liver.", "23 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 63 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a liver cancer, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "neurofibroma of gallbladder", "metastase of liver cancer", "childhood cancer of liver", "liver carcinoma", "hepatoblastoma", "liver sarcoma", "hepatic osteogenic sarcoma", "liver lymphoma", "adult primary liver cancer", "recurrent cancer of liver", "localized resectable adult primary liver cancer", "calcifying nested epithelial stromal tumor of the liver" ] } ], "standing": "Described in 63 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 23 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one liver cancer from another, and a liver cancer from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a liver cancer sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a liver cancer from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a liver cancer passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a liver cancer between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a liver cancer, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a liver cancer is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of liver cancer a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define liver cancer, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover liver cancer, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How liver cancer develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does liver cancer typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for liver cancer, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a liver cancer came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a liver cancer and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a liver cancer is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a liver cancer, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a liver cancer, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a liver cancer is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }