{ "model": { "rank": 9415, "code": "thing-q633403", "model_id": "vr.tr.asthenia", "name": "asthenia", "purpose": "Let an agent explain asthenia as a symptom in general terms from clinical sources, describe common causes and assessment, distinguish asthenia from fatigue, muscle weakness and specific syndromes, and route personal concerns to clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.QLT", "industry": "", "version": "", "url": "/models/thing/q633403/", "tier": 2, "score": 47, "payload": { "layer": "wikidata", "aliases": [ "marasmos", "muscle weakness", "wasting away", "adynamia", "cerebrasthenia", "debility", "functional weakness", "motor weakness", "limb weakness", "palate weakness", "peripheral muscle weakness", "neck weakness", "sternocleidomastoid weakness", "deltoid muscle weakness", "Bulbar palsy", "weak feet", "episodic muscle weakness, X-linked", "Ocular myasthenia" ], "aliasCount": 18, "merged": 18, "knownIn": 47, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q633403", "url": "https://www.wikidata.org/wiki/Q633403", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-13T04:06:08Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude" }, "metaModel": { "id": "THING-Q633403", "registryId": "vr.tr.asthenia", "name": "asthenia", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.QLT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q633403/", "model": { "registry_id": "vr.tr.asthenia", "name": "asthenia", "purpose": "Let an agent explain asthenia as a symptom in general terms from clinical sources, describe common causes and assessment, distinguish asthenia from fatigue, muscle weakness and specific syndromes, and route personal concerns to clinicians.", "definition": "Abnormal physical weakness or lack of energy and strength, a symptom rather than a disease, ranging from generalised debility, adynamia and wasting as in marasmus to specific muscle weakness, and historically named as neurasthenia and cerebrasthenia for fatigue attributed to nervous exhaustion; asthenia accompanies infections, chronic illness, malnutrition, anaemia, endocrine and neurological disorders, depression and ageing, and needs assessment of its cause.", "what_it_is_for": "Not applicable; a clinical sign.", "affordances": [ "explain the symptom", "relay causes and assessment", "distinguish related concepts", "route personal concerns" ], "distinguishing_features": [ "Symptom not disease", "Many causes", "Generalised or focal", "Historical concepts" ], "appearance": "Not a visible object; reduced strength and energy.", "visual_identification": [ "Abnormal weakness or lack of energy", "Generalised debility, adynamia, wasting, muscle weakness, historical neurasthenia and cerebrasthenia", "Fatigue is tiredness; paralysis is loss of movement; frailty is an age-related syndrome" ], "physical_properties": [], "families_and_kinds": [ "generalised asthenia and debility", "muscle weakness from neuromuscular disease", "wasting and marasmus from malnutrition", "asthenia in infection and chronic illness", "post-viral and chronic fatigue states", "historical neurasthenia and cerebrasthenia" ], "related_models": [ { "relation": "is a kind of", "target": "weakness", "why": "in registry terms" }, { "relation": "is a kind of", "target": "symptom", "why": "in registry terms" }, { "relation": "is a kind of", "target": "clinical sign", "why": "in registry terms" }, { "relation": "is distinguished from", "target": "fatigue", "why": "as tiredness" } ], "identifiers": [ { "scheme": "ICD-11", "value_or_pattern": "MG22", "note": "fatigue related terms" }, { "scheme": "MeSH", "value_or_pattern": "D001247", "note": "asthenia" } ], "standards_and_regulation": [ "Clinical guidelines on evaluating weakness and fatigue", "Nutritional guidelines for marasmus" ], "failure_modes_and_hazards": [ "Missing serious causes such as neuromuscular disease or cancer", "Agents giving personal medical advice", "Confusing asthenia with fatigue or laziness" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "help", "name": "Help", "description": "Urgent signs first.", "rationale": "Safety.", "layers": [ { "id": "urgent", "name": "Urgent", "description": "Urgent weakness.", "findings": [ { "id": "urgent-finding", "name": "Urgent", "description": "Urgent.", "questions": [ { "text": "Which forms of weakness, such as sudden, one-sided or with breathing difficulty, need emergency care?", "kind": "action" }, { "text": "Is the user describing such signs, which need emergency services now?", "kind": "boundary" } ] } ] }, { "id": "assessment", "name": "Assessment", "description": "Assessment.", "findings": [ { "id": "assessment-finding", "name": "Assessment", "description": "Assessment.", "questions": [ { "text": "How do clinicians assess asthenia and find its cause, in general terms?", "kind": "provenance" }, { "text": "Is the user asking about their own weakness, which needs a clinician?", "kind": "boundary" } ] } ] } ] }, { "id": "understand", "name": "Understand", "description": "The symptom.", "rationale": "Clinical.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is asthenia, and how does it differ from fatigue, muscle weakness, paralysis and frailty?", "kind": "definition" }, { "text": "Is the question about the symptom or a specific disease?", "kind": "boundary" } ] } ] }, { "id": "causes", "name": "Causes", "description": "Causes.", "findings": [ { "id": "causes-finding", "name": "Causes", "description": "Causes.", "questions": [ { "text": "What causes asthenia, from infection and anaemia to malnutrition, endocrine and neuromuscular disease?", "kind": "provenance" }, { "text": "Which entry fits the specific cause?", "kind": "action" } ] } ] } ] }, { "id": "manage", "name": "Manage", "description": "Management.", "rationale": "Clinical.", "layers": [ { "id": "treatment", "name": "Treatment", "description": "Treatment.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "How is asthenia managed by treating the cause, nutrition and rehabilitation, per guidelines?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "chronic", "name": "Chronic", "description": "Chronic fatigue states.", "findings": [ { "id": "chronic-finding", "name": "Chronic", "description": "Chronic.", "questions": [ { "text": "How are post-viral and chronic fatigue states understood, with research attributed?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "History.", "rationale": "Context.", "layers": [ { "id": "history", "name": "History", "description": "Neurasthenia and history.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "What were neurasthenia and cerebrasthenia, and how did these concepts change?", "kind": "provenance" }, { "text": "Which entry fits neurasthenia?", "kind": "action" } ] } ] }, { "id": "nutrition", "name": "Nutrition", "description": "Marasmus.", "findings": [ { "id": "nutrition-finding", "name": "Nutrition", "description": "Nutrition.", "questions": [ { "text": "What is marasmus, and how is severe malnutrition treated?", "kind": "provenance" }, { "text": "Which entry fits marasmus?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should muscle weakness and marasmus be separate primary entries?", "How should clinical guidelines be linked?", "The registry entry has merged aliases naming historical concepts; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "abstract concept", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a asthenia, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain asthenia as a symptom in general terms from clinical sources, describe common causes and assessment, distinguish asthenia from fatigue, muscle weakness and specific syndromes, and route personal concerns to clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: marasmos, muscle weakness, wasting away, adynamia, cerebrasthenia, debility, functional weakness, motor weakness, limb weakness, palate weakness, peripheral muscle weakness, neck weakness.", "18 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 47 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a asthenia, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Nothing to see. What is recognised is an instance of it, and which instances count is exactly what is argued about." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "marasmos", "muscle weakness", "wasting away", "adynamia", "cerebrasthenia", "debility", "functional weakness", "motor weakness", "limb weakness", "palate weakness", "peripheral muscle weakness", "neck weakness" ] } ], "standing": "Described in 47 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 18 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one asthenia from another, and a asthenia from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a asthenia sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a asthenia from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a asthenia passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a asthenia between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a asthenia, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a asthenia is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "definitions-in-contest", "name": "Definitions and who holds them", "description": "What asthenia is taken to mean, and by whom.", "rationale": "When a field disagrees about a concept, the disagreement is the content. A model that picks one definition silently destroys the information.", "layers": [ { "id": "competing-definitions", "name": "Competing definitions", "description": "The main readings and the traditions behind them.", "findings": [ { "id": "definition-map", "name": "Definitions and their holders", "description": "Each definition with the school or body that holds it.", "questions": [ { "id": "definition-map-q01", "text": "Which definitions of asthenia are in use, and which tradition or body holds each?", "kind": "definition" }, { "id": "definition-map-q02", "text": "What turns on the difference between them in practice?", "kind": "boundary" } ] } ] }, { "id": "operationalisation", "name": "Operationalisation", "description": "How it is measured or applied when it has to be.", "findings": [ { "id": "operational-record", "name": "Measures and proxies", "description": "Instruments and indicators used to stand in for it.", "questions": [ { "id": "operational-record-q01", "text": "How is asthenia operationalised or measured in practice, and by what instrument?", "kind": "measurement" }, { "id": "operational-record-q02", "text": "What does that operationalisation leave out, and when does that matter?", "kind": "boundary" } ] } ] } ] }, { "id": "instances-and-use", "name": "Instances, use and consequence", "description": "What counts as an instance of asthenia and what follows from calling something that.", "rationale": "Applying a concept is an act with consequences, so a model must say what the label licenses and what it does not.", "layers": [ { "id": "instances", "name": "What counts as an instance", "description": "Clear cases, borderline cases and non-cases.", "findings": [ { "id": "instance-tests", "name": "Tests for an instance", "description": "What would settle whether something falls under it.", "questions": [ { "id": "instance-tests-q01", "text": "What would settle whether something is an instance of asthenia?", "kind": "boundary" }, { "id": "instance-tests-q02", "text": "Which borderline cases are argued about, and on what grounds?", "kind": "definition" } ] } ] }, { "id": "consequence", "name": "Consequence of application", "description": "Rights, duties or decisions that follow from the label.", "findings": [ { "id": "consequence-record", "name": "What the label licenses", "description": "What an agent may do once something is classified this way.", "questions": [ { "id": "consequence-record-q01", "text": "What follows practically once something is treated as asthenia?", "kind": "action" }, { "id": "consequence-record-q02", "text": "What must an agent not infer from the label alone?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a asthenia came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a asthenia and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a asthenia is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a asthenia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a asthenia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a asthenia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }