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Research draft

herpes simplex

vr.tr.herpes-simplex · XCT.QLT

Let an agent explain herpes simplex infection in general terms, relay prevention, testing and treatment information from health authorities, describe complications that need urgent care, and route personal symptoms and treatment questions to clinicians and sexual health services.

Thing Registry Cross-cutting context

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain herpes simplex infection in general terms, relay prevention, testing and treatment information from health authorities, describe complications that need urgent care, and route personal symptoms and treatment questions to clinicians and sexual health services.

A common viral infection caused by herpes simplex virus types 1 and 2, producing recurrent blisters and sores on the lips and face or in the genital area, and less often infections of the eye, skin elsewhere or the nervous system; the virus persists for life in nerve cells and reactivates periodically, and antiviral medicines shorten and reduce episodes.

What it is for: Not applicable; an infection.

It can be explain types, transmission and course; relay prevention and treatment guidance; describe complications needing urgent care; route personal questions to clinicians.

Distinguishing features

Lifelong latent infection with reactivation

Two virus types with overlapping sites

Very common and often asymptomatic

Manageable with antivirals

What it looks like

Not visible as an object; clusters of small blisters that break into sores, on the lips or genitals, often with tingling before.

Physical character

HSV-1 prevalence: about two thirds of adults worldwide - WHO estimates

HSV-2 prevalence: about one in eight adults aged 15-49 - WHO estimates

How it is recognised

Recurrent blisters and sores in the same area

HSV-1 mostly oral, HSV-2 mostly genital, with overlap

Herpes zoster is a different virus; canker sores are not viral

Related models

is a kind of - the category

viral infection

is caused by - the pathogen

herpes simplex virus

is confused with - a different herpesvirus disease

herpes zoster

is treated by - such as aciclovir

antiviral drug

In practice

Families and kinds

oral herpes or cold sores

genital herpes

herpes keratitis of the eye

herpetic whitlow and skin infections

neonatal herpes

herpes encephalitis, rare and serious

Identifiers

ICD-10 B00 and A60 oral and genital

ICD-11 1F00

Standards and regulation

WHO and national guidelines on genital herpes

Antenatal guidance on neonatal herpes prevention

Sexual health service standards

Failure modes and hazards

Neonatal herpes from transmission at birth

Eye involvement threatening sight

Encephalitis, rare and serious

Stigma and agents giving personal medical advice

Also called

Herpes simplex virus hepatitisherpes simplex virus keratitisHerpes simplex virus otitis externagenital herpesstromal keratitisdendritic keratitisneonatal herpes simplexeczema herpeticumHerpes labialisHerpes esophagitisherpetic whitlowherpes gladiatorumherpetic gastritisElsberg syndromeidiopathic recurrent and disabling cutaneous herpes

Where this came from

wikidata · CC0 1.0

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand What herpes simplex is.

General information.

Cause

Cause and transmission.

Cause

Cause.

  1. What causes herpes simplex, how is it transmitted, and how does latency and reactivation work? definition
  2. Is the user describing their own symptoms, which need a clinician or sexual health service? boundary

Recognise

Signs.

Recognise

Recognise.

  1. What do episodes look like, and how are they distinguished from other conditions? definition
  2. Which entry fits herpes zoster or another condition? action
Care Testing and treatment.

Clinical.

Testing

Testing.

Testing

Testing.

  1. When is testing advised, and how is it accessed, according to guidelines? provenance
  2. Which services provide testing locally? action

Treatment

Treatment.

Treatment

Treatment.

  1. What treatments do guidelines describe, including suppressive therapy? provenance
  2. Is the presentation free of personal treatment advice? boundary
Prevent Prevention and complications.

Public health.

Prevention

Prevention.

Prevention

Prevention.

  1. What prevention measures do authorities recommend, including in pregnancy? provenance
  2. Which entry fits neonatal herpes? action

Urgent

Warning signs.

Urgent

Urgent.

  1. Which signs, such as eye involvement or neurological symptoms, need urgent care? provenance
  2. Is the user describing an emergency, which must be routed? boundary
Society Stigma and research.

Context.

Stigma

Stigma and support.

Stigma

Stigma.

  1. What do health bodies say about stigma, and what support exists? provenance
  2. Is the presentation non-stigmatising? boundary

Research

Research.

Research

Research.

  1. What research exists on vaccines and treatments, with attribution? provenance
  2. Which references are standard? provenance

What the second pass must settle

  • Should oral and genital herpes be separate entries?
  • How should guidelines be linked by country?
  • The registry entry has merged aliases for rare complications; should they be split off?