{
    "model": {
        "rank": 6827,
        "code": "thing-q652744",
        "model_id": "vr.tr.hand-foot-and-mouth-disease",
        "name": "hand, foot and mouth disease",
        "purpose": "Enable an agent to recognise hand, foot and mouth disease, assess an attributed illness episode, and identify appropriate assessment, care and transmission-control actions from documented evidence.",
        "family": "Thing Registry",
        "category": "Cross-cutting context",
        "status": "research-draft",
        "kind": "thing",
        "plane": "XCT",
        "domain": "XCT.QLT",
        "industry": "",
        "version": "",
        "url": "/models/thing/q652744/",
        "tier": 2,
        "score": 58,
        "payload": {
            "layer": "wikidata",
            "aliases": [],
            "aliasCount": 0,
            "merged": 0,
            "knownIn": 58,
            "facets": null,
            "markers": [],
            "lexicalClass": "",
            "senseRank": null,
            "alsoRegisteredAs": null,
            "source": {
                "dataset": "wikidata",
                "item": "Q652744",
                "url": "https://www.wikidata.org/wiki/Q652744",
                "license": "CC0 1.0"
            }
        },
        "research": {
            "vercy": "1.0-draft",
            "publication": {
                "status": "research-draft",
                "adjudicationStatus": "unreviewed",
                "publishableCanonical": false,
                "generatedAt": "2026-09-09T23:35:32Z",
                "providers": [
                    "Codex"
                ],
                "breadth": "recalled by Codex without web access - no source was read",
                "missingProviders": [],
                "pass": 2,
                "cost": {
                    "grok": {
                        "seconds": 19.7,
                        "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a08885-d664-7253-9cbe-e690081c1c30\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: hand, foot and mouth disease\nSense to describe: (none recorded)\nDomain code: XCT.STA\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Ba",
                        "usd": 0,
                        "recall": true
                    },
                    "codex": {
                        "seconds": 65,
                        "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a08885-d678-7bd2-a17f-fe87b30e42fc\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: hand, foot and mouth disease\nRegistry id: vr.tr.hand-foot-and-mouth-disease\nPlane / domain: XCT / XCT.STA\nRegistry definition: (none recorded)\nNames "
                    }
                }
            },
            "metaModel": {
                "id": "THING-Q652744",
                "registryId": "vr.tr.hand-foot-and-mouth-disease",
                "name": "hand, foot and mouth disease",
                "version": "0.1.0-research.1",
                "entryKind": "thing",
                "family": "Thing Registry",
                "domain": [
                    "XCT.STA"
                ],
                "status": "research-draft"
            },
            "canonicalUrl": "https://ver.cy/models/thing/q652744/",
            "model": {
                "registry_id": "vr.tr.hand-foot-and-mouth-disease",
                "name": "hand, foot and mouth disease",
                "purpose": "Enable an agent to recognise hand, foot and mouth disease, assess an attributed illness episode, and identify appropriate assessment, care and transmission-control actions from documented evidence.",
                "definition": "Hand, foot and mouth disease is an acute contagious illness caused by several enteroviruses, typically producing fever, oral vesicles or ulcers, and a rash on the hands and feet, predominantly in young children.",
                "scope_statement": "This model owns the disease concept vr.tr.hand-foot-and-mouth-disease in XCT / XCT.STA, including its clinical boundaries, causal attribution, episode states and disease-specific decision requirements; it links to patients, diagnostic assertions and care encounters without equating them with the disease.",
                "in_scope": [
                    "Clinical recognition of typical, incomplete and atypical presentations",
                    "Enterovirus attribution and interpretation of supporting laboratory evidence",
                    "Episode timing, hydration, severity, complications and recovery",
                    "Exposure, transmission and setting-specific prevention decisions",
                    "Versioned diagnostic definitions, terminology mappings and population evidence"
                ],
                "out_of_scope": [
                    "The patient's complete health record and unrelated conditions",
                    "Care encounters, staffing, billing and treatment administration records",
                    "General enterovirus taxonomy and laboratory assay specifications",
                    "Animal foot-and-mouth disease",
                    "Independent models of alternative rash illnesses",
                    "Institution-wide outbreak management beyond HFMD-specific requirements"
                ],
                "distinguishing_features": [
                    "Check that the concept concerns human HFMD rather than animal foot-and-mouth disease, which is unrelated. [CDC causes](https://www.cdc.gov/hand-foot-mouth/causes/index.html)",
                    "Assess the combination of mouth sores and hand or foot rash, with fever recorded separately; do not infer the diagnosis from the disease name alone. [CDC symptoms](https://www.cdc.gov/hand-foot-mouth/signs-symptoms/index.html)",
                    "Require lesion distribution and oral examination evidence when comparing HFMD with an oral-only syndrome or another vesicular rash.",
                    "Distinguish clinical HFMD from an enterovirus-positive result: record the clinical syndrome and pathogen evidence as separate assertions.",
                    "Treat age as contextual evidence rather than an exclusion rule: HFMD is common below age five but can affect other ages. [CDC overview](https://www.cdc.gov/hand-foot-mouth/index.html)"
                ],
                "characteristics": [
                    {
                        "name": "Diagnostic assertion",
                        "kind": "state",
                        "unit_or_values": "Suspected, clinically diagnosed, laboratory-supported, rejected or unresolved; retain the issuing definition",
                        "why_it_matters": "Prevents a provisional label or positive assay from silently becoming a confirmed disease episode."
                    },
                    {
                        "name": "Lesion phenotype",
                        "kind": "category",
                        "unit_or_values": "Oral and skin sites, morphology, pain, extent; absent, present or unexamined at each site",
                        "why_it_matters": "Supports recognition and comparison with competing explanations."
                    },
                    {
                        "name": "Episode timing",
                        "kind": "measurement",
                        "unit_or_values": "Dates and elapsed days for fever, oral lesions, skin lesions and recovery; uncertainty recorded",
                        "why_it_matters": "Makes progression and persistent symptoms interpretable."
                    },
                    {
                        "name": "Hydration evidence",
                        "kind": "measurement",
                        "unit_or_values": "Fluid intake in mL over a stated interval when available, urine frequency and clinician-assessed hydration",
                        "why_it_matters": "Connects painful oral symptoms to a concrete assessment need."
                    },
                    {
                        "name": "Severity and complication assessment",
                        "kind": "state",
                        "unit_or_values": "Assessment pending, uncomplicated, complication suspected or complication documented; criteria and timestamp required",
                        "why_it_matters": "Supports escalation without assuming that every episode follows the usual course."
                    },
                    {
                        "name": "Causal attribution",
                        "kind": "relation",
                        "unit_or_values": "Episode linked to an identified or suspected enterovirus, supporting specimen and assay, or unknown agent",
                        "why_it_matters": "HFMD has multiple viral causes; the syndrome does not establish a particular virus. [CDC causes](https://www.cdc.gov/hand-foot-mouth/causes/index.html)"
                    },
                    {
                        "name": "Exposure setting",
                        "kind": "relation",
                        "unit_or_values": "Household, childcare, school or other contact setting, with exposure dates and confidence",
                        "why_it_matters": "Supports plausible exposure assessment and targeted prevention."
                    },
                    {
                        "name": "Terminology mapping",
                        "kind": "relation",
                        "unit_or_values": "Coding system, jurisdiction, release, code, preferred term and mapping fidelity",
                        "why_it_matters": "Keeps administrative classification distinct from clinical diagnostic evidence."
                    }
                ],
                "affordances": [
                    "Compare a documented oral and skin presentation with a sourced HFMD case definition and flag missing observations.",
                    "Track an episode's symptom course and hydration evidence to identify reassessment needs.",
                    "Associate laboratory evidence with an episode while preserving uncertainty about causal attribution.",
                    "Retrieve applicable clinical guidance when severity or complications require assessment.",
                    "Determine which local attendance, hygiene and reporting guidance applies to the affected setting.",
                    "Compare population estimates only after aligning case definitions, denominators, locations and periods."
                ]
            },
            "sources": [],
            "structure": {
                "bundles": [
                    {
                        "id": "syndrome-recognition",
                        "name": "Syndrome recognition",
                        "description": "Evidence needed to recognise HFMD and keep its diagnostic boundaries explicit.",
                        "rationale": "The characteristic name can encourage diagnosis from an incomplete symptom checklist.",
                        "layers": [
                            {
                                "id": "oral-and-cutaneous-pattern",
                                "name": "Oral and cutaneous pattern",
                                "description": "Observed lesion sites, morphology and accompanying symptoms.",
                                "findings": [
                                    {
                                        "id": "documented-presentation",
                                        "name": "Documented presentation",
                                        "description": "Record oral lesions, hand and foot involvement, other affected sites and fever independently, including unexamined sites.",
                                        "questions": [
                                            {
                                                "text": "Which oral and skin sites were examined, and what lesion morphology, pain and distribution were documented?",
                                                "kind": "measurement",
                                                "id": "documented-presentation-q01"
                                            },
                                            {
                                                "text": "Which sourced definition supports recognising this presentation as typical, incomplete or atypical HFMD?",
                                                "kind": "definition",
                                                "id": "documented-presentation-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "diagnostic-boundaries",
                                "name": "Diagnostic boundaries",
                                "description": "Competing explanations and the status of the diagnostic assertion.",
                                "findings": [
                                    {
                                        "id": "differential-and-confidence",
                                        "name": "Differential and confidence",
                                        "description": "Keep competing diagnoses and unresolved evidence visible rather than treating all oral ulcers or acral rashes as HFMD.",
                                        "questions": [
                                            {
                                                "text": "What observations support HFMD over herpangina, gingivostomatitis, varicella or another explanation for this presentation?",
                                                "kind": "boundary",
                                                "id": "differential-and-confidence-q01"
                                            },
                                            {
                                                "text": "Who assigned the diagnostic status, on what date, and using which clinical or surveillance definition?",
                                                "kind": "provenance",
                                                "id": "differential-and-confidence-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "viral-attribution",
                        "name": "Viral attribution",
                        "description": "Causal evidence and its limits for the HFMD syndrome.",
                        "rationale": "An agent must distinguish a clinical syndrome, a detected virus and a supported causal claim.",
                        "layers": [
                            {
                                "id": "etiologic-identity",
                                "name": "Etiologic identity",
                                "description": "Attribution to a specific enterovirus where evidence permits.",
                                "findings": [
                                    {
                                        "id": "attributed-enterovirus",
                                        "name": "Attributed enterovirus",
                                        "description": "Allow unknown attribution and distinguish suspected from identified agents, including coxsackievirus A16, coxsackievirus A6 and EV-A71. [CDC causes](https://www.cdc.gov/hand-foot-mouth/causes/index.html)",
                                        "questions": [
                                            {
                                                "text": "Is the attributed virus supported by testing of this episode, inferred from an outbreak, or unknown?",
                                                "kind": "provenance",
                                                "id": "attributed-enterovirus-q01"
                                            },
                                            {
                                                "text": "Does the evidence identify a particular viral type or only a broader enterovirus group?",
                                                "kind": "boundary",
                                                "id": "attributed-enterovirus-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "laboratory-interpretation",
                                "name": "Laboratory interpretation",
                                "description": "Specimen, timing and assay context needed to interpret a result.",
                                "findings": [
                                    {
                                        "id": "episode-linked-test-evidence",
                                        "name": "Episode-linked test evidence",
                                        "description": "Represent laboratory results with their collection context and interpretive limits; do not make testing a universal prerequisite without a cited definition.",
                                        "questions": [
                                            {
                                                "text": "Which specimen and assay produced the result, and when was collection relative to symptom onset?",
                                                "kind": "measurement",
                                                "id": "episode-linked-test-evidence-q01"
                                            },
                                            {
                                                "text": "What does the applicable guidance allow this result to establish about the current HFMD episode?",
                                                "kind": "boundary",
                                                "id": "episode-linked-test-evidence-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "course-and-care-decisions",
                        "name": "Course and care decisions",
                        "description": "Episode progression and evidence that changes assessment or care needs.",
                        "rationale": "Oral pain, hydration and uncommon complications matter more to action than the disease label alone.",
                        "layers": [
                            {
                                "id": "symptoms-and-hydration",
                                "name": "Symptoms and hydration",
                                "description": "Symptom trajectory and ability to maintain intake.",
                                "findings": [
                                    {
                                        "id": "oral-pain-and-fluid-balance",
                                        "name": "Oral pain and fluid balance",
                                        "description": "Record drinking difficulty alongside intake and hydration observations. Painful mouth sores can interfere with swallowing. [CDC symptoms](https://www.cdc.gov/hand-foot-mouth/signs-symptoms/index.html)",
                                        "questions": [
                                            {
                                                "text": "How have mouth pain, drinking, urine output and fever changed since onset?",
                                                "kind": "measurement",
                                                "id": "oral-pain-and-fluid-balance-q01"
                                            },
                                            {
                                                "text": "Which age-appropriate, sourced criteria indicate that hydration or symptom control needs clinical reassessment?",
                                                "kind": "action",
                                                "id": "oral-pain-and-fluid-balance-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "complications-and-resolution",
                                "name": "Complications and resolution",
                                "description": "Evidence for escalation, recovery or reconsideration of the diagnosis.",
                                "findings": [
                                    {
                                        "id": "departure-from-expected-course",
                                        "name": "Departure from expected course",
                                        "description": "Separate recovery assessment from suspected complications and record the criteria behind escalation; most children have mild symptoms lasting 7 to 10 days. [CDC symptoms](https://www.cdc.gov/hand-foot-mouth/signs-symptoms/index.html)",
                                        "questions": [
                                            {
                                                "text": "Are symptoms improving, persisting or worsening, and are there documented neurologic or other complication concerns?",
                                                "kind": "measurement",
                                                "id": "departure-from-expected-course-q01"
                                            },
                                            {
                                                "text": "Which current guideline determines the urgency of assessment and the evidence required to mark this episode resolved?",
                                                "kind": "action",
                                                "id": "departure-from-expected-course-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "transmission-and-setting",
                        "name": "Transmission and setting",
                        "description": "Exposure evidence and context-specific prevention requirements.",
                        "rationale": "An individual HFMD episode can require actions involving household or group settings.",
                        "layers": [
                            {
                                "id": "exposure-and-clustering",
                                "name": "Exposure and clustering",
                                "description": "Contact history and links to other episodes.",
                                "findings": [
                                    {
                                        "id": "plausible-exposure-links",
                                        "name": "Plausible exposure links",
                                        "description": "Record temporally plausible contacts and cluster membership without asserting a proven transmission chain.",
                                        "questions": [
                                            {
                                                "text": "Which household, childcare, school or other contacts occurred before onset, and on what dates?",
                                                "kind": "measurement",
                                                "id": "plausible-exposure-links-q01"
                                            },
                                            {
                                                "text": "What evidence supports linking this episode to a cluster rather than merely sharing a setting?",
                                                "kind": "provenance",
                                                "id": "plausible-exposure-links-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "prevention-and-participation",
                                "name": "Prevention and participation",
                                "description": "Applicable guidance for hygiene, attendance and notification.",
                                "findings": [
                                    {
                                        "id": "setting-specific-actions",
                                        "name": "Setting-specific actions",
                                        "description": "Attach prevention and participation decisions to a named authority, jurisdiction and effective date; keep clinical recovery distinct from permission to return.",
                                        "questions": [
                                            {
                                                "text": "Which local HFMD guidance governs hygiene, childcare or school attendance, and outbreak notification?",
                                                "kind": "provenance",
                                                "id": "setting-specific-actions-q01"
                                            },
                                            {
                                                "text": "Given the recorded symptoms and setting, what actions does that guidance require and when must they be reviewed?",
                                                "kind": "action",
                                                "id": "setting-specific-actions-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "classification-and-population-evidence",
                        "name": "Classification and population evidence",
                        "description": "Versioned concept mappings and interpretable measures of disease occurrence.",
                        "rationale": "Codes and case counts can describe different boundaries unless their definitions travel with them.",
                        "layers": [
                            {
                                "id": "versioned-concept-mapping",
                                "name": "Versioned concept mapping",
                                "description": "Relationship between the registry concept and clinical terminologies.",
                                "findings": [
                                    {
                                        "id": "verified-disease-mappings",
                                        "name": "Verified disease mappings",
                                        "description": "Require verification of ICD-10, ICD-11 and SNOMED CT mappings in the applicable releases, including whether each mapping is exact or broader.",
                                        "questions": [
                                            {
                                                "text": "Which verified codes and preferred terms map to HFMD in the relevant ICD and SNOMED CT releases?",
                                                "kind": "provenance",
                                                "id": "verified-disease-mappings-q01"
                                            },
                                            {
                                                "text": "Does each mapping denote the disease itself, a broader enteroviral syndrome, or a different recordable concept?",
                                                "kind": "boundary",
                                                "id": "verified-disease-mappings-q02"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "population-and-surveillance",
                                "name": "Population and surveillance",
                                "description": "Population context for reported HFMD occurrence and severity.",
                                "findings": [
                                    {
                                        "id": "denominated-frequency",
                                        "name": "Denominated frequency",
                                        "description": "Distinguish incidence, prevalence, notified cases and hospital series; retain age range, location, period, denominator and ascertainment method.",
                                        "questions": [
                                            {
                                                "text": "What population, year, denominator and case definition support the reported HFMD frequency?",
                                                "kind": "measurement",
                                                "id": "denominated-frequency-q01"
                                            },
                                            {
                                                "text": "How do reporting coverage, testing selection and recruitment setting limit comparison with other estimates?",
                                                "kind": "boundary",
                                                "id": "denominated-frequency-q02"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "evidence-and-external-alignment",
                        "name": "Evidence and external alignment",
                        "description": "What the world already says about this thing, gathered so the model can be checked against it.",
                        "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.",
                        "layers": [
                            {
                                "id": "reported-evidence",
                                "name": "Reported evidence",
                                "description": "Findings from the breadth pass, kept separate from the structural claims.",
                                "findings": [
                                    {
                                        "id": "evidence-confidence-notes",
                                        "name": "Check these first",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            "This is recalled knowledge, not source-verified research; no sources were consulted.",
                                            "Verify coding revisions, national reporting requirements, and any formal surveillance case definition before operational use.",
                                            "Timing ranges are approximate; prevalence, pathogen distribution, and complication rates require a specified population, period, and source."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-confidence-notes-q01",
                                                "text": "Which of these check these first hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-kinds",
                                        "name": "Kinds and varieties",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            "Typical hand, foot and mouth disease",
                                            "Atypical hand, foot and mouth disease, often associated with coxsackievirus A6"
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-kinds-q01",
                                                "text": "Which of these kinds and varieties hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-identifiers",
                                        "name": "Identifiers and schemes",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            {
                                                "scheme": "WHO ICD-10",
                                                "value_or_pattern": "B08.4",
                                                "note": "Enteroviral vesicular stomatitis with exanthem; confirm the applicable national modification and revision when coding."
                                            }
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-identifiers-q01",
                                                "text": "Which of these identifiers and schemes hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-standards-and-regulation",
                                        "name": "Standards and regulation",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            "World Health Organization ICD-10 classifies the disease under B08.4; this classification is not a diagnostic criterion set."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-standards-and-regulation-q01",
                                                "text": "Which of these standards and regulation hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-real-world-use",
                                        "name": "Real-world use",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            "Clinical recognition of a usually self-limited childhood infectious illness",
                                            "Surveillance and investigation of outbreaks in childcare settings and schools",
                                            "Enterovirus testing and typing in selected severe, atypical, or outbreak-associated cases",
                                            "Distinguishing the disease from an individual infection episode, the recorded diagnosis, and the encounter providing care"
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-real-world-use-q01",
                                                "text": "Which of these real-world use hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-measurements",
                                        "name": "Typical measurements",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            {
                                                "quantity": "Incubation period",
                                                "typical_range": "Approximately 3-6",
                                                "unit": "days"
                                            },
                                            {
                                                "quantity": "Usual duration of uncomplicated illness",
                                                "typical_range": "Approximately 7-10",
                                                "unit": "days"
                                            }
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-measurements-q01",
                                                "text": "Which of these typical measurements hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-failure-modes-and-hazards",
                                        "name": "Failure modes and hazards",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            "Painful mouth lesions can reduce fluid intake and cause dehydration.",
                                            "Transmission can occur through fecal contamination, respiratory and oral secretions, blister fluid, and contaminated objects.",
                                            "Rare neurological complications include meningitis, encephalitis, and acute flaccid paralysis, particularly with enterovirus A71.",
                                            "Severe enterovirus A71-associated disease can involve cardiopulmonary deterioration.",
                                            "Atypical widespread lesions can be mistaken for other vesicular skin diseases; temporary nail shedding can follow recovery."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-failure-modes-and-hazards-q01",
                                                "text": "Which of these failure modes and hazards hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-regional-variation",
                                        "name": "Regional variation",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            "Circulating enterovirus types and the proportion of severe cases vary by place and outbreak.",
                                            "Large outbreaks associated with enterovirus A71 have been especially prominent in parts of East and Southeast Asia.",
                                            "Seasonality varies with climate, with summer and autumn peaks common in temperate regions."
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-regional-variation-q01",
                                                "text": "Which of these regional variation hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    },
                                    {
                                        "id": "evidence-neighbours",
                                        "name": "Neighbouring kinds and how to tell them apart",
                                        "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                                        "evidence": [
                                            {
                                                "name": "Foot-and-mouth disease",
                                                "difference": "A distinct aphthovirus infection principally affecting cloven-hoofed animals; it is not the human enteroviral illness."
                                            },
                                            {
                                                "name": "Herpangina",
                                                "difference": "An enteroviral syndrome with lesions predominantly in the posterior mouth and throat, usually without the characteristic hand and foot rash."
                                            },
                                            {
                                                "name": "Varicella",
                                                "difference": "Caused by varicella-zoster virus and typically produces a generalized itchy eruption with lesions in successive stages."
                                            },
                                            {
                                                "name": "Primary herpetic gingivostomatitis",
                                                "difference": "Usually caused by herpes simplex virus, with prominent gingival inflammation and painful oral lesions rather than the characteristic acral eruption."
                                            }
                                        ],
                                        "questions": [
                                            {
                                                "id": "evidence-neighbours-q01",
                                                "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of hand, foot and mouth disease this model covers, and on what evidence?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "openQuestions": [
                "Which issuing bodies and current revisions provide the clinical and surveillance definitions needed for the intended jurisdictions, including atypical presentations?",
                "What are the verified ICD-10, ICD-11 and SNOMED CT mappings, release identifiers and mapping limitations for this registry concept?",
                "Which age-specific escalation and recovery criteria should govern hydration concerns, persistent symptoms and suspected complications?",
                "Which current local policies govern attendance, reporting and prevention, including any locally available vaccination programme and its viral coverage?",
                "Which population-based studies provide comparable HFMD incidence or prevalence estimates with explicit age groups, locations, years and ascertainment methods?"
            ],
            "statistics": {
                "bundles": 6,
                "layers": 11,
                "findings": 19,
                "questions": 29
            }
        },
        "draft": {
            "generator": "vr.draft.v3",
            "status": "draft-generated",
            "researched": false,
            "archetype": "disease or condition",
            "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.",
            "facetsInferred": true,
            "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.",
            "purpose": "Give an agent a durable, checkable way to recognise a hand, foot and mouth disease, record what state it is in, and decide what may be done with it.",
            "whatItIs": "Enable an agent to recognise hand, foot and mouth disease, assess an attributed illness episode, and identify appropriate assessment, care and transmission-control actions from documented evidence.",
            "characteristics": {
                "substance": "abstract",
                "origin": "conceptual",
                "agency": "inert"
            },
            "whatYouCanDoWithIt": [
                "observed and measured"
            ],
            "distinguishingFeatures": [
                "Described in 58 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is."
            ],
            "openQuestionsForResearch": [
                "Which of the bundles below does a real task actually need, and which are ceremony?",
                "What does this thing have that the facets do not capture at all?",
                "Which neighbouring kind is most often confused with a hand, foot and mouth disease, and on what evidence are they told apart?"
            ],
            "whatItIsMadeOf": "an abstraction with no physical instance",
            "physicalCharacter": [
                "Does nothing on its own; everything it does, something else did to it.",
                "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing."
            ],
            "whatCanBeDoneWithIt": [
                "observe it, measure it, record its state"
            ],
            "howItIsRecognised": [
                "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test."
            ],
            "relatedModels": [],
            "standing": "Described in 58 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is.",
            "structure": {
                "bundles": [
                    {
                        "id": "identity-and-classification",
                        "name": "Identity, naming and classification",
                        "description": "How an agent tells one hand, foot and mouth disease from another, and a hand, foot and mouth disease from things that resemble it.",
                        "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.",
                        "layers": [
                            {
                                "id": "naming-and-identifiers",
                                "name": "Names and identifiers",
                                "description": "The names this thing goes by and the identifiers that survive translation and time.",
                                "findings": [
                                    {
                                        "id": "preferred-name-and-aliases",
                                        "name": "Preferred name, aliases and local names",
                                        "description": "Which name to use, which names mean the same thing, and which merely sound similar.",
                                        "questions": [
                                            {
                                                "id": "preferred-name-and-aliases-q01",
                                                "text": "What identifies and describes the name of a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q02",
                                                "text": "Who or what asserted this about the name of a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q03",
                                                "text": "What may an agent decide or do once the name of a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "stable-identifiers",
                                        "name": "Stable identifiers and external keys",
                                        "description": "Identifiers that keep pointing at this kind of thing across systems and languages.",
                                        "questions": [
                                            {
                                                "id": "stable-identifiers-q01",
                                                "text": "What identifies and describes an identifier for a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q02",
                                                "text": "Who or what asserted this about an identifier for a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q03",
                                                "text": "What may an agent decide or do once an identifier for a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "classification-and-granularity",
                                "name": "Classification and granularity",
                                "description": "Where a hand, foot and mouth disease sits among kinds, and how finely a task needs to cut it.",
                                "findings": [
                                    {
                                        "id": "kind-and-parents",
                                        "name": "Kind, parents and neighbouring kinds",
                                        "description": "The classes this thing belongs to and the ones it is next to.",
                                        "questions": [
                                            {
                                                "id": "kind-and-parents-q01",
                                                "text": "What identifies and describes the kind of a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q02",
                                                "text": "Who or what asserted this about the kind of a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q03",
                                                "text": "What may an agent decide or do once the kind of a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "distinguishing-features",
                                        "name": "Distinguishing features",
                                        "description": "What separates a hand, foot and mouth disease from the things most often confused with it.",
                                        "questions": [
                                            {
                                                "id": "distinguishing-features-q01",
                                                "text": "What identifies and describes what distinguishes a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q02",
                                                "text": "Who or what asserted this about what distinguishes a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q03",
                                                "text": "What may an agent decide or do once what distinguishes a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "state-and-lifecycle",
                        "name": "State and lifecycle",
                        "description": "The states a hand, foot and mouth disease passes through and the events that move it between them.",
                        "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.",
                        "layers": [
                            {
                                "id": "lifecycle-stages",
                                "name": "Lifecycle stages",
                                "description": "From coming into existence to ceasing to be one of these.",
                                "findings": [
                                    {
                                        "id": "stages-and-transitions",
                                        "name": "Stages and transitions",
                                        "description": "The stages worth naming and what moves a hand, foot and mouth disease between them.",
                                        "questions": [
                                            {
                                                "id": "stages-and-transitions-q01",
                                                "text": "What identifies and describes the lifecycle of a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q02",
                                                "text": "Who or what asserted this about the lifecycle of a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q03",
                                                "text": "What may an agent decide or do once the lifecycle of a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "observations-and-status",
                                "name": "Observations and current status",
                                "description": "What is observed about a hand, foot and mouth disease, how often and by whom.",
                                "findings": [
                                    {
                                        "id": "observation-record",
                                        "name": "Observation record",
                                        "description": "How an observation of a hand, foot and mouth disease is recorded so that it can be superseded rather than overwritten.",
                                        "questions": [
                                            {
                                                "id": "observation-record-q01",
                                                "text": "What identifies and describes an observation of a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q02",
                                                "text": "Who or what asserted this about an observation of a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q03",
                                                "text": "What may an agent decide or do once an observation of a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "diagnosis-and-criteria",
                        "name": "Diagnosis, criteria and coding",
                        "description": "What makes a case of hand, foot and mouth disease a case, and under which revision.",
                        "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.",
                        "layers": [
                            {
                                "id": "criteria",
                                "name": "Diagnostic criteria",
                                "description": "The criteria in force and who issues them.",
                                "findings": [
                                    {
                                        "id": "criteria-record",
                                        "name": "Criteria, issuer and revision",
                                        "description": "What must be true for a diagnosis, according to whom.",
                                        "questions": [
                                            {
                                                "id": "criteria-record-q01",
                                                "text": "What criteria define hand, foot and mouth disease, issued by which body, in which revision?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "criteria-record-q02",
                                                "text": "What changed between revisions that would reclassify existing cases?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "coding",
                                "name": "Coding and terminology",
                                "description": "The codes used to record it and their mapping.",
                                "findings": [
                                    {
                                        "id": "coding-record",
                                        "name": "Codes and mappings",
                                        "description": "Which classification codes apply and how they map.",
                                        "questions": [
                                            {
                                                "id": "coding-record-q01",
                                                "text": "Which classification and terminology codes cover hand, foot and mouth disease, and how do they map to each other?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "coding-record-q02",
                                                "text": "What is lost when a case is mapped from one scheme to another?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "course-and-population",
                        "name": "Course, population and care",
                        "description": "How hand, foot and mouth disease develops, whom it affects, and what is done about it.",
                        "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.",
                        "layers": [
                            {
                                "id": "course",
                                "name": "Course and stages",
                                "description": "Onset, progression, remission and outcome.",
                                "findings": [
                                    {
                                        "id": "course-record",
                                        "name": "Stages and transitions",
                                        "description": "The stages recorded and what moves a case between them.",
                                        "questions": [
                                            {
                                                "id": "course-record-q01",
                                                "text": "What course does hand, foot and mouth disease typically take, and what marks each stage?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "course-record-q02",
                                                "text": "What separates the condition itself from an episode of care for it?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "population",
                                "name": "Affected populations",
                                "description": "Who is affected, how often, and on what evidence.",
                                "findings": [
                                    {
                                        "id": "epidemiology",
                                        "name": "Prevalence and its basis",
                                        "description": "Rates with their population, period and source.",
                                        "questions": [
                                            {
                                                "id": "epidemiology-q01",
                                                "text": "What prevalence or incidence is reported for hand, foot and mouth disease, in which population and period?",
                                                "kind": "measurement"
                                            },
                                            {
                                                "id": "epidemiology-q02",
                                                "text": "What may an agent not conclude about an individual from a population rate?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "provenance-and-evidence",
                        "name": "Provenance, evidence and time",
                        "description": "Where every claim about a hand, foot and mouth disease came from and when it held.",
                        "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.",
                        "layers": [
                            {
                                "id": "source-and-authority",
                                "name": "Source and authority",
                                "description": "Who said it, on what evidence, and how strongly.",
                                "findings": [
                                    {
                                        "id": "claim-provenance",
                                        "name": "Claim provenance and confidence",
                                        "description": "The authority behind each claim about a hand, foot and mouth disease and how confident it is.",
                                        "questions": [
                                            {
                                                "id": "claim-provenance-q01",
                                                "text": "What identifies and describes a claim about a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q02",
                                                "text": "Who or what asserted this about a claim about a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q03",
                                                "text": "What may an agent decide or do once a claim about a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "time-and-versions",
                                "name": "Time, versions and supersession",
                                "description": "When a claim was true, when it was learnt, and what replaced it.",
                                "findings": [
                                    {
                                        "id": "validity-and-supersession",
                                        "name": "Validity period and supersession",
                                        "description": "How an old claim about a hand, foot and mouth disease is retired without being erased.",
                                        "questions": [
                                            {
                                                "id": "validity-and-supersession-q01",
                                                "text": "What identifies and describes the validity of a claim about a hand, foot and mouth disease, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q02",
                                                "text": "Who or what asserted this about the validity of a claim about a hand, foot and mouth disease, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q03",
                                                "text": "What may an agent decide or do once the validity of a claim about a hand, foot and mouth disease is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "statistics": {
                "bundles": 5,
                "layers": 10,
                "findings": 12,
                "questions": 32
            }
        }
    }
}