{ "model": { "rank": 2770, "code": "thing-q6853", "model_id": "vr.tr.hepatitis-b", "name": "hepatitis B", "purpose": "Let an agent explain hepatitis B and its course in neutral clinical terms, relay transmission, prevention, testing and treatment from public health and hepatology sources, describe hepatitis D co-infection, and route people at risk or with symptoms to testing and clinicians.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.QLT", "industry": "", "version": "", "url": "/models/thing/q6853/", "tier": 2, "score": 97, "payload": { "layer": "wikidata", "aliases": [ "hepatitis D", "chronic hepatitis B", "chronic hepatitis D", "Lábrea fever" ], "aliasCount": 4, "merged": 4, "knownIn": 97, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q6853", "url": "https://www.wikidata.org/wiki/Q6853", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-13T05:44:28Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude" }, "metaModel": { "id": "THING-Q6853", "registryId": "vr.tr.hepatitis-b", "name": "hepatitis B", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.QLT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q6853/", "model": { "registry_id": "vr.tr.hepatitis-b", "name": "hepatitis B", "purpose": "Let an agent explain hepatitis B and its course in neutral clinical terms, relay transmission, prevention, testing and treatment from public health and hepatology sources, describe hepatitis D co-infection, and route people at risk or with symptoms to testing and clinicians.", "definition": "A viral infection of the liver caused by the hepatitis B virus, transmitted through blood, sexual contact and from mother to child at birth, which may be acute and self-limiting or become chronic, especially when acquired in infancy, leading over decades to cirrhosis and liver cancer, and which can be complicated by co-infection with the hepatitis D virus, a defective virus that requires hepatitis B to replicate and causes severe forms such as the Labrea fever of the Amazon; hepatitis B is preventable by vaccination and treatable with antiviral drugs.", "what_it_is_for": "Not applicable; a disease.", "affordances": [ "explain the disease and course", "relay prevention and treatment", "describe hepatitis D", "route to testing and care" ], "distinguishing_features": [ "Blood-borne and perinatal", "Chronic carriage", "Vaccine-preventable", "Hepatitis D dependence" ], "appearance": "Not a visible object; jaundice in some acute cases, often silent.", "visual_identification": [ "Liver infection by hepatitis B virus", "Acute and chronic hepatitis B, hepatitis D co-infection and superinfection, Labrea fever", "Hepatitis A and E spread by food and water; hepatitis C is a different blood-borne virus" ], "physical_properties": [ { "quantity": "people with chronic infection", "typical_range": "about 250", "unit": "million", "note": "WHO estimates" }, { "quantity": "annual deaths", "typical_range": "about 1", "unit": "million", "note": "mostly cirrhosis and cancer" }, { "quantity": "vaccine introduced", "typical_range": "1982", "unit": "year", "note": "" }, { "quantity": "hepatitis D discovered", "typical_range": "1977", "unit": "year", "note": "" } ], "families_and_kinds": [ "acute hepatitis B", "chronic hepatitis B", "hepatitis D co-infection and superinfection including chronic hepatitis D", "severe regional forms such as Labrea fever", "occult and resolved infection", "hepatitis B genotypes" ], "related_models": [ { "relation": "is a kind of", "target": "viral hepatitis", "why": "in registry terms" }, { "relation": "is a kind of", "target": "Hepadnaviridae infectious disease", "why": "in registry terms" }, { "relation": "is caused by", "target": "hepatitis B virus", "why": "of the Hepadnaviridae" }, { "relation": "is prevented by", "target": "hepatitis B vaccine", "why": "in infancy and at-risk groups" } ], "identifiers": [ { "scheme": "ICD-11", "value_or_pattern": "1E51.0", "note": "chronic hepatitis B" }, { "scheme": "MeSH", "value_or_pattern": "D006509", "note": "hepatitis B" } ], "standards_and_regulation": [ "WHO guidelines on hepatitis B prevention, testing and treatment", "Universal infant vaccination programmes", "Blood donation screening rules", "Notifiable disease reporting" ], "failure_modes_and_hazards": [ "Agents giving personal medical advice", "Stigma toward people living with hepatitis B", "Missed diagnosis of silent chronic infection" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "help", "name": "Help", "description": "Testing and care first.", "rationale": "Safety.", "layers": [ { "id": "testing", "name": "Testing", "description": "Who should test.", "findings": [ { "id": "testing-finding", "name": "Testing", "description": "Testing.", "questions": [ { "text": "Why do people with risk exposures, or from high-prevalence regions, or with symptoms such as jaundice, need testing and clinical care?", "kind": "action" }, { "text": "Is the user asking about their own exposure or result, which needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "living", "name": "Living", "description": "Living with hepatitis B.", "findings": [ { "id": "living-finding", "name": "Living", "description": "Living.", "questions": [ { "text": "What support and monitoring do people with chronic hepatitis B receive, and how is stigma addressed?", "kind": "provenance" }, { "text": "Is the presentation free of stigma?", "kind": "boundary" } ] } ] } ] }, { "id": "understand", "name": "Understand", "description": "The disease.", "rationale": "Clinical.", "layers": [ { "id": "course", "name": "Course", "description": "Course.", "findings": [ { "id": "course-finding", "name": "Course", "description": "Course.", "questions": [ { "text": "How does hepatitis B progress from acute infection to chronic disease, cirrhosis and cancer?", "kind": "definition" }, { "text": "Is the question about hepatitis B, hepatitis D or another hepatitis?", "kind": "boundary" } ] } ] }, { "id": "transmission", "name": "Transmission", "description": "Transmission.", "findings": [ { "id": "transmission-finding", "name": "Transmission", "description": "Transmission.", "questions": [ { "text": "How is hepatitis B transmitted, and how does hepatitis D depend on it?", "kind": "definition" }, { "text": "Which entry fits hepatitis D?", "kind": "action" } ] } ] } ] }, { "id": "prevent", "name": "Prevent", "description": "Prevention and treatment.", "rationale": "Public health.", "layers": [ { "id": "vaccine", "name": "Vaccine", "description": "Vaccination.", "findings": [ { "id": "vaccine-finding", "name": "Vaccine", "description": "Vaccine.", "questions": [ { "text": "How do vaccination, birth-dose programmes and screening prevent hepatitis B, according to WHO?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatment.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "How are chronic hepatitis B and hepatitis D treated with antivirals and newer drugs, in general terms?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Epidemiology and research.", "rationale": "Context.", "layers": [ { "id": "epidemiology", "name": "Epidemiology", "description": "Epidemiology.", "findings": [ { "id": "epidemiology-finding", "name": "Epidemiology", "description": "Epidemiology.", "questions": [ { "text": "Where is hepatitis B most common, and what are elimination targets, with data attributed?", "kind": "provenance" }, { "text": "Which entry fits viral hepatitis elimination?", "kind": "action" } ] } ] }, { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research pursues a cure for hepatitis B and treatments for hepatitis D?", "kind": "provenance" }, { "text": "Which entry fits hepatitis B virus?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should hepatitis D be a separate primary entry?", "How should public health guidelines be linked?", "The registry entry has merged hepatitis D aliases; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "abstract concept", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a hepatitis B, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain hepatitis B and its course in neutral clinical terms, relay transmission, prevention, testing and treatment from public health and hepatology sources, describe hepatitis D co-infection, and route people at risk or with symptoms to testing and clinicians.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: hepatitis D, chronic hepatitis B, chronic hepatitis D, Lábrea fever.", "4 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 97 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a hepatitis B, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Nothing to see. What is recognised is an instance of it, and which instances count is exactly what is argued about." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "hepatitis D", "chronic hepatitis B", "chronic hepatitis D", "Lábrea fever" ] } ], "standing": "Described in 97 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 4 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one hepatitis B from another, and a hepatitis B from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a hepatitis B sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a hepatitis B from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a hepatitis B passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a hepatitis B between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a hepatitis B, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a hepatitis B is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "definitions-in-contest", "name": "Definitions and who holds them", "description": "What hepatitis B is taken to mean, and by whom.", "rationale": "When a field disagrees about a concept, the disagreement is the content. A model that picks one definition silently destroys the information.", "layers": [ { "id": "competing-definitions", "name": "Competing definitions", "description": "The main readings and the traditions behind them.", "findings": [ { "id": "definition-map", "name": "Definitions and their holders", "description": "Each definition with the school or body that holds it.", "questions": [ { "id": "definition-map-q01", "text": "Which definitions of hepatitis B are in use, and which tradition or body holds each?", "kind": "definition" }, { "id": "definition-map-q02", "text": "What turns on the difference between them in practice?", "kind": "boundary" } ] } ] }, { "id": "operationalisation", "name": "Operationalisation", "description": "How it is measured or applied when it has to be.", "findings": [ { "id": "operational-record", "name": "Measures and proxies", "description": "Instruments and indicators used to stand in for it.", "questions": [ { "id": "operational-record-q01", "text": "How is hepatitis B operationalised or measured in practice, and by what instrument?", "kind": "measurement" }, { "id": "operational-record-q02", "text": "What does that operationalisation leave out, and when does that matter?", "kind": "boundary" } ] } ] } ] }, { "id": "instances-and-use", "name": "Instances, use and consequence", "description": "What counts as an instance of hepatitis B and what follows from calling something that.", "rationale": "Applying a concept is an act with consequences, so a model must say what the label licenses and what it does not.", "layers": [ { "id": "instances", "name": "What counts as an instance", "description": "Clear cases, borderline cases and non-cases.", "findings": [ { "id": "instance-tests", "name": "Tests for an instance", "description": "What would settle whether something falls under it.", "questions": [ { "id": "instance-tests-q01", "text": "What would settle whether something is an instance of hepatitis B?", "kind": "boundary" }, { "id": "instance-tests-q02", "text": "Which borderline cases are argued about, and on what grounds?", "kind": "definition" } ] } ] }, { "id": "consequence", "name": "Consequence of application", "description": "Rights, duties or decisions that follow from the label.", "findings": [ { "id": "consequence-record", "name": "What the label licenses", "description": "What an agent may do once something is classified this way.", "questions": [ { "id": "consequence-record-q01", "text": "What follows practically once something is treated as hepatitis B?", "kind": "action" }, { "id": "consequence-record-q02", "text": "What must an agent not infer from the label alone?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a hepatitis B came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a hepatitis B and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a hepatitis B is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a hepatitis B, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a hepatitis B, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a hepatitis B is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }