{ "model": { "rank": 18016, "code": "thing-q692536", "model_id": "vr.tr.muscular-disease", "name": "muscular disease", "purpose": "Let an agent give general, non-diagnostic information about muscle diseases, flag urgent symptoms, and route people to specialists and patient organisations.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q692536/", "tier": 2, "score": 30, "payload": { "layer": "wikidata", "aliases": [ "muscle neoplasm", "abdominal rigidity", "muscle symptom", "flaccidity", "flaccid muscle tone", "sinoatrial node disease", "polymyalgia rheumatica", "decreased tongue tone", "hereditary myopathy with lactic acidosis due to ISCU deficiency", "acquired skeletal muscle disease", "congenital cataract-progressive muscular hypotonia-hearing loss-developmental delay syndrome", "hereditary proximal myopathy with early respiratory failure", "myopathy of critical illness", "dysferlinopathy", "periodic paralysis with transient compartment-like syndrome", "Acquired non-inflammatory myopathy", "proximal myopathy with extrapyramidal signs", "metabolic myopathy", "neurogenic scapuloperoneal syndrome, Kaeser type", "congenital myopathy, Paradas type", "spheroid body myopathy", "Hereditary inclusion body myopathy", "metabolic myopathy due to lactate transporter defect", "autosomal dominant mitochondrial myopathy with exercise intolerance", "muscular lipidosis", "myofibrillar myopathy 5", "proximal myopathy and ophthalmoplegia", "myofibrillar myopathy 3", "muscle diastasis", "muscular hypertonia, lethal", "neonatal hypotonia", "tubular aggregate myopathy 2", "GNE myopathy", "acute myopathy of intensive care", "White striping", "gas gangrene", "myotilinopathy", "muscle rigidity", "hypotonia", "periodic paralysis" ], "aliasCount": 83, "merged": 84, "knownIn": 30, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q692536", "url": "https://www.wikidata.org/wiki/Q692536", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-11T07:52:46Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 1, "engine": "claude" }, "metaModel": { "id": "THING-Q692536", "registryId": "vr.tr.muscular-disease", "name": "muscular disease", "version": "0.2.0-wave.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q692536/", "model": { "registry_id": "vr.tr.muscular-disease", "name": "muscular disease", "purpose": "Let an agent give general, non-diagnostic information about muscle diseases, flag urgent symptoms, and route people to specialists and patient organisations.", "definition": "Any disease or disorder affecting muscle, such as muscular dystrophies, myopathies, myositis, disorders of muscle tone and rare muscle tumours; the registry also lists some unrelated conditions.", "what_it_is_for": "A group of medical conditions diagnosed and treated by health professionals.", "affordances": [ "seek assessment for weakness or pain", "access neuromuscular specialists", "find patient support organisations", "get urgent care for severe symptoms" ], "distinguishing_features": [ "Disorders of muscle", "Inherited or acquired", "Wide range of severity", "Specialist diagnosis" ], "appearance": "Not described; symptoms may include weakness, pain, stiffness or reduced tone.", "visual_identification": [ "Conditions such as muscular dystrophy or myositis", "Tests such as CK levels, EMG and biopsy", "Some registry aliases belong to other organ systems" ], "physical_properties": [], "families_and_kinds": [ "muscular dystrophies", "inflammatory myopathies", "metabolic and mitochondrial myopathies", "disorders of muscle tone", "muscle tumours" ], "related_models": [ { "relation": "is a kind of", "target": "musculoskeletal disorder", "why": "category" }, { "relation": "affects", "target": "muscle", "why": "tissue" }, { "relation": "is treated by", "target": "neurologist and neuromuscular specialist", "why": "professionals" }, { "relation": "is related to", "target": "nerve disease", "why": "neuromuscular" } ], "identifiers": [ { "scheme": "ICD-11", "value_or_pattern": "various codes in chapters 8 and 15", "note": "muscle diseases" } ], "standards_and_regulation": [ "Clinical guidelines for neuromuscular disease", "Rare disease networks such as ERN EURO-NMD" ], "failure_modes_and_hazards": [ "Diagnosis by an agent", "Missing urgent signs such as breathing or swallowing difficulty", "Unproven treatments" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "urgent", "name": "Urgent", "description": "Red flags first.", "rationale": "Some symptoms need urgent care.", "layers": [ { "id": "red-flags", "name": "Red flags", "description": "Breathing and swallowing.", "findings": [ { "id": "red-flags-finding", "name": "Red flags", "description": "Urgent signs.", "questions": [ { "text": "Are there signs such as difficulty breathing or swallowing that need urgent care?", "kind": "boundary" }, { "text": "Who should be called?", "kind": "action" } ] } ] }, { "id": "assessment", "name": "Assessment", "description": "See a doctor.", "findings": [ { "id": "assessment-finding", "name": "Assessment", "description": "Assessment.", "questions": [ { "text": "Should new weakness or muscle pain be assessed by a doctor?", "kind": "boundary" }, { "text": "How soon?", "kind": "boundary" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Diagnosis and treatment.", "rationale": "Specialists diagnose.", "layers": [ { "id": "tests", "name": "Tests", "description": "Investigations.", "findings": [ { "id": "tests-finding", "name": "Tests", "description": "Investigations.", "questions": [ { "text": "Which tests might specialists use?", "kind": "definition" }, { "text": "What do they involve?", "kind": "definition" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Options.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "Which treatments do guidelines describe for this condition?", "kind": "provenance" }, { "text": "Who decides with the patient?", "kind": "boundary" } ] } ] } ] }, { "id": "living", "name": "Living with it", "description": "Support.", "rationale": "Support improves life.", "layers": [ { "id": "therapy", "name": "Therapy", "description": "Physio and aids.", "findings": [ { "id": "therapy-finding", "name": "Therapy", "description": "Therapy and aids.", "questions": [ { "text": "Which therapies and aids can help daily life?", "kind": "action" }, { "text": "How are they accessed?", "kind": "action" } ] } ] }, { "id": "organisations", "name": "Organisations", "description": "Patient groups.", "findings": [ { "id": "organisations-finding", "name": "Organisations", "description": "Patient organisations.", "questions": [ { "text": "Which patient organisations offer support?", "kind": "action" }, { "text": "Are there clinical trial registries?", "kind": "provenance" } ] } ] } ] }, { "id": "information", "name": "Information", "description": "Understanding.", "rationale": "Reliable information helps.", "layers": [ { "id": "types", "name": "Types", "description": "Conditions.", "findings": [ { "id": "types-finding", "name": "Types", "description": "Condition types.", "questions": [ { "text": "Which condition is meant?", "kind": "definition" }, { "text": "Which specific entry fits?", "kind": "action" } ] } ] }, { "id": "genetics", "name": "Genetics", "description": "Inheritance.", "findings": [ { "id": "genetics-finding", "name": "Genetics", "description": "Genetics.", "questions": [ { "text": "Is the condition inherited, and is genetic counselling available?", "kind": "boundary" }, { "text": "Who provides it?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should muscle disease groups be separate entries?", "How should misfiled aliases be moved?", "How should patient organisations be localised?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "disease or condition", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a muscular disease, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent give general, non-diagnostic information about muscle diseases, flag urgent symptoms, and route people to specialists and patient organisations.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: muscle neoplasm, abdominal rigidity, muscle symptom, flaccidity, flaccid muscle tone, sinoatrial node disease, polymyalgia rheumatica, decreased tongue tone, hereditary myopathy with lactic acidosis due to ISCU deficiency, acquired skeletal muscle disease, congenital cataract-progressive muscular hypotonia-hearing loss-developmental delay syndrome, hereditary proximal myopathy with early respiratory failure.", "84 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 30 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a muscular disease, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Recognised by criteria applied to signs and findings, not by appearance. Two conditions can look identical and be distinguished only by test." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "muscle neoplasm", "abdominal rigidity", "muscle symptom", "flaccidity", "flaccid muscle tone", "sinoatrial node disease", "polymyalgia rheumatica", "decreased tongue tone", "hereditary myopathy with lactic acidosis due to ISCU deficiency", "acquired skeletal muscle disease", "congenital cataract-progressive muscular hypotonia-hearing loss-developmental delay syndrome", "hereditary proximal myopathy with early respiratory failure" ] } ], "standing": "Described in 30 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 84 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one muscular disease from another, and a muscular disease from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a muscular disease sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a muscular disease from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a muscular disease passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a muscular disease between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a muscular disease, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a muscular disease is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "diagnosis-and-criteria", "name": "Diagnosis, criteria and coding", "description": "What makes a case of muscular disease a case, and under which revision.", "rationale": "Criteria change between revisions, so a diagnosis without its coding revision cannot be compared with a later one.", "layers": [ { "id": "criteria", "name": "Diagnostic criteria", "description": "The criteria in force and who issues them.", "findings": [ { "id": "criteria-record", "name": "Criteria, issuer and revision", "description": "What must be true for a diagnosis, according to whom.", "questions": [ { "id": "criteria-record-q01", "text": "What criteria define muscular disease, issued by which body, in which revision?", "kind": "definition" }, { "id": "criteria-record-q02", "text": "What changed between revisions that would reclassify existing cases?", "kind": "boundary" } ] } ] }, { "id": "coding", "name": "Coding and terminology", "description": "The codes used to record it and their mapping.", "findings": [ { "id": "coding-record", "name": "Codes and mappings", "description": "Which classification codes apply and how they map.", "questions": [ { "id": "coding-record-q01", "text": "Which classification and terminology codes cover muscular disease, and how do they map to each other?", "kind": "definition" }, { "id": "coding-record-q02", "text": "What is lost when a case is mapped from one scheme to another?", "kind": "boundary" } ] } ] } ] }, { "id": "course-and-population", "name": "Course, population and care", "description": "How muscular disease develops, whom it affects, and what is done about it.", "rationale": "The condition, the diagnosis and the episode of care are three different things, and an agent must not merge them.", "layers": [ { "id": "course", "name": "Course and stages", "description": "Onset, progression, remission and outcome.", "findings": [ { "id": "course-record", "name": "Stages and transitions", "description": "The stages recorded and what moves a case between them.", "questions": [ { "id": "course-record-q01", "text": "What course does muscular disease typically take, and what marks each stage?", "kind": "definition" }, { "id": "course-record-q02", "text": "What separates the condition itself from an episode of care for it?", "kind": "boundary" } ] } ] }, { "id": "population", "name": "Affected populations", "description": "Who is affected, how often, and on what evidence.", "findings": [ { "id": "epidemiology", "name": "Prevalence and its basis", "description": "Rates with their population, period and source.", "questions": [ { "id": "epidemiology-q01", "text": "What prevalence or incidence is reported for muscular disease, in which population and period?", "kind": "measurement" }, { "id": "epidemiology-q02", "text": "What may an agent not conclude about an individual from a population rate?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a muscular disease came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a muscular disease and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a muscular disease is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a muscular disease, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a muscular disease, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a muscular disease is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }