{ "model": { "rank": 14643, "code": "thing-q762713", "model_id": "vr.tr.hypercholesterolemia", "name": "hypercholesterolemia", "purpose": "Let an agent explain hypercholesterolemia at a general, factual level from medical sources, relay its causes, the inherited form and general management, describe the forms its aliases name, and route personal concerns to a clinician.", "family": "Thing Registry", "category": "Cross-cutting context", "status": "research-draft", "kind": "thing", "plane": "XCT", "domain": "XCT.STA", "industry": "", "version": "", "url": "/models/thing/q762713/", "tier": 2, "score": 35, "payload": { "layer": "wikidata", "aliases": [ "familial hypercholesterolemia", "familial hypercholesterolemia 1", "hypercholesterolemia, familial, 2", "pediatric hypercholesterolemia", "homozygous familial hypercholesterolemia", "autosomal recessive hypercholesterolemia", "hypercholesterolemia, autosomal dominant, type b" ], "aliasCount": 7, "merged": 7, "knownIn": 35, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": "vr.tr.hypercholesterolemia", "source": { "dataset": "wikidata", "item": "Q762713", "url": "https://www.wikidata.org/wiki/Q762713", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-14T04:01:23Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 4, "engine": "claude" }, "metaModel": { "id": "THING-Q762713", "registryId": "vr.tr.hypercholesterolemia", "name": "hypercholesterolemia", "version": "0.2.0-wave.4", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q762713/", "model": { "registry_id": "vr.tr.hypercholesterolemia", "name": "hypercholesterolemia", "purpose": "Let an agent explain hypercholesterolemia at a general, factual level from medical sources, relay its causes, the inherited form and general management, describe the forms its aliases name, and route personal concerns to a clinician.", "definition": "Hypercholesterolemia is the presence of high levels of cholesterol in the blood, a risk factor for cardiovascular disease; the registry aliases name forms such as familial hypercholesterolemia, an inherited form, and its subtypes. High cholesterol often has no symptoms and is found by a blood test, and it is managed with diet, lifestyle and medicines. This entry gives general, factual information, and any personal situation should be directed to a qualified clinician.", "what_it_is_for": "Not applicable; a medical condition.", "affordances": [ "explain the condition generally", "relay causes and forms", "note general management", "route personal concerns to a clinician" ], "distinguishing_features": [ "High cholesterol", "Often symptomless", "Inherited and acquired forms", "Cardiovascular risk" ], "appearance": "Not a visible object; a raised blood cholesterol level found by testing.", "visual_identification": [ "High blood cholesterol", "Familial hypercholesterolemia and its subtypes", "It is a lipid level, not a symptom; the inherited form differs from diet-related high cholesterol" ], "physical_properties": [ { "quantity": "feature", "typical_range": "high blood cholesterol", "unit": "note", "note": "" }, { "quantity": "significance", "typical_range": "cardiovascular risk factor", "unit": "note", "note": "" }, { "quantity": "registry parent", "typical_range": "hyperlipidemia", "unit": "note", "note": "" } ], "families_and_kinds": [ "acquired hypercholesterolemia", "familial hypercholesterolemia", "homozygous familial form" ], "related_models": [ { "relation": "is a kind of", "target": "hyperlipidemia", "why": "in registry terms" }, { "relation": "is a risk factor for", "target": "cardiovascular disease", "why": "" }, { "relation": "is contrasted with", "target": "normal cholesterol", "why": "" }, { "relation": "is found by", "target": "blood test", "why": "" } ], "identifiers": [], "standards_and_regulation": [ "Clinical lipid guidelines" ], "failure_modes_and_hazards": [ "Offering personal diagnosis", "Confusing inherited and acquired forms", "Understating or overstating risk" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What it is.", "rationale": "Attribution.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is hypercholesterolemia, and how does the inherited form differ from the acquired one?", "kind": "definition" }, { "text": "Is this a personal medical situation that needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "forms", "name": "Forms", "description": "Named forms.", "findings": [ { "id": "forms-finding", "name": "Forms", "description": "Forms.", "questions": [ { "text": "What are familial and homozygous familial hypercholesterolemia?", "kind": "definition" }, { "text": "Which entry fits the specific form?", "kind": "action" } ] } ] } ] }, { "id": "causes", "name": "Causes", "description": "Causes.", "rationale": "Sources.", "layers": [ { "id": "acquired", "name": "Acquired", "description": "Acquired causes.", "findings": [ { "id": "acquired-finding", "name": "Acquired", "description": "Acquired.", "questions": [ { "text": "What lifestyle and dietary factors raise cholesterol?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "inherited", "name": "Inherited", "description": "Inherited causes.", "findings": [ { "id": "inherited-finding", "name": "Inherited", "description": "Inherited.", "questions": [ { "text": "How is familial hypercholesterolemia inherited?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Care.", "rationale": "Attribution.", "layers": [ { "id": "detection", "name": "Detection", "description": "Detection.", "findings": [ { "id": "detection-finding", "name": "Detection", "description": "Detection.", "questions": [ { "text": "How is high cholesterol detected by testing?", "kind": "provenance" }, { "text": "Is diagnosis left to a clinician?", "kind": "boundary" } ] } ] }, { "id": "management", "name": "Management", "description": "Management.", "findings": [ { "id": "management-finding", "name": "Management", "description": "Management.", "questions": [ { "text": "How is hypercholesterolemia managed, in general terms?", "kind": "provenance" }, { "text": "Where should care be sought?", "kind": "action" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Context.", "rationale": "Attribution.", "layers": [ { "id": "risk", "name": "Risk", "description": "Cardiovascular risk.", "findings": [ { "id": "risk-finding", "name": "Risk", "description": "Risk.", "questions": [ { "text": "Why is high cholesterol a cardiovascular risk factor?", "kind": "provenance" }, { "text": "Is the information general rather than personal?", "kind": "boundary" } ] } ] }, { "id": "prevention", "name": "Prevention", "description": "Prevention.", "findings": [ { "id": "prevention-finding", "name": "Prevention", "description": "Prevention.", "questions": [ { "text": "How is high cholesterol reduced in general terms?", "kind": "provenance" }, { "text": "Is personal advice left to a clinician?", "kind": "boundary" } ] } ] } ] } ] }, "openQuestions": [ "Should forms be separate entries?", "How should the inherited form be explained?", "How should personal concerns be routed?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "abstract concept", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a hypercholesterolemia, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain hypercholesterolemia at a general, factual level from medical sources, relay its causes, the inherited form and general management, describe the forms its aliases name, and route personal concerns to a clinician.", "characteristics": { "substance": "abstract", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: familial hypercholesterolemia, familial hypercholesterolemia 1, hypercholesterolemia, familial, 2, pediatric hypercholesterolemia, homozygous familial hypercholesterolemia, autosomal recessive hypercholesterolemia, hypercholesterolemia, autosomal dominant, type b.", "7 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 35 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a hypercholesterolemia, and on what evidence are they told apart?" ], "whatItIsMadeOf": "an abstraction with no physical instance", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Nothing to see. What is recognised is an instance of it, and which instances count is exactly what is argued about." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "familial hypercholesterolemia", "familial hypercholesterolemia 1", "hypercholesterolemia, familial, 2", "pediatric hypercholesterolemia", "homozygous familial hypercholesterolemia", "autosomal recessive hypercholesterolemia", "hypercholesterolemia, autosomal dominant, type b" ] } ], "standing": "Described in 35 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 7 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one hypercholesterolemia from another, and a hypercholesterolemia from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a hypercholesterolemia sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a hypercholesterolemia from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a hypercholesterolemia passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a hypercholesterolemia between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a hypercholesterolemia, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a hypercholesterolemia is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "definitions-in-contest", "name": "Definitions and who holds them", "description": "What hypercholesterolemia is taken to mean, and by whom.", "rationale": "When a field disagrees about a concept, the disagreement is the content. A model that picks one definition silently destroys the information.", "layers": [ { "id": "competing-definitions", "name": "Competing definitions", "description": "The main readings and the traditions behind them.", "findings": [ { "id": "definition-map", "name": "Definitions and their holders", "description": "Each definition with the school or body that holds it.", "questions": [ { "id": "definition-map-q01", "text": "Which definitions of hypercholesterolemia are in use, and which tradition or body holds each?", "kind": "definition" }, { "id": "definition-map-q02", "text": "What turns on the difference between them in practice?", "kind": "boundary" } ] } ] }, { "id": "operationalisation", "name": "Operationalisation", "description": "How it is measured or applied when it has to be.", "findings": [ { "id": "operational-record", "name": "Measures and proxies", "description": "Instruments and indicators used to stand in for it.", "questions": [ { "id": "operational-record-q01", "text": "How is hypercholesterolemia operationalised or measured in practice, and by what instrument?", "kind": "measurement" }, { "id": "operational-record-q02", "text": "What does that operationalisation leave out, and when does that matter?", "kind": "boundary" } ] } ] } ] }, { "id": "instances-and-use", "name": "Instances, use and consequence", "description": "What counts as an instance of hypercholesterolemia and what follows from calling something that.", "rationale": "Applying a concept is an act with consequences, so a model must say what the label licenses and what it does not.", "layers": [ { "id": "instances", "name": "What counts as an instance", "description": "Clear cases, borderline cases and non-cases.", "findings": [ { "id": "instance-tests", "name": "Tests for an instance", "description": "What would settle whether something falls under it.", "questions": [ { "id": "instance-tests-q01", "text": "What would settle whether something is an instance of hypercholesterolemia?", "kind": "boundary" }, { "id": "instance-tests-q02", "text": "Which borderline cases are argued about, and on what grounds?", "kind": "definition" } ] } ] }, { "id": "consequence", "name": "Consequence of application", "description": "Rights, duties or decisions that follow from the label.", "findings": [ { "id": "consequence-record", "name": "What the label licenses", "description": "What an agent may do once something is classified this way.", "questions": [ { "id": "consequence-record-q01", "text": "What follows practically once something is treated as hypercholesterolemia?", "kind": "action" }, { "id": "consequence-record-q02", "text": "What must an agent not infer from the label alone?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a hypercholesterolemia came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a hypercholesterolemia and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a hypercholesterolemia is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a hypercholesterolemia, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a hypercholesterolemia, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a hypercholesterolemia is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 5, "layers": 10, "findings": 12, "questions": 32 } } } }