{
    "model": {
        "rank": 4346,
        "code": "thing-q83330",
        "model_id": "vr.tr.lysosome",
        "name": "lysosome",
        "purpose": "Let an agent explain lysosomes and their functions, relay structure, formation and enzymes from cell biology references, describe lysosomal storage diseases in general terms, and distinguish lysosomes from related organelles.",
        "family": "Thing Registry",
        "category": "Physical world and living systems",
        "status": "research-draft",
        "kind": "thing",
        "plane": "PHY",
        "domain": "PHY.LIV",
        "industry": "",
        "version": "",
        "url": "/models/thing/q83330/",
        "tier": 2,
        "score": 76,
        "payload": {
            "layer": "wikidata",
            "aliases": [
                "mast cell granule",
                "cytolytic granule",
                "secondary lysosome",
                "endolysosome",
                "primary lysosome",
                "megasome",
                "Lysosome of muscle cell"
            ],
            "aliasCount": 7,
            "merged": 9,
            "knownIn": 76,
            "facets": null,
            "markers": [],
            "lexicalClass": "",
            "senseRank": null,
            "alsoRegisteredAs": null,
            "source": {
                "dataset": "wikidata",
                "item": "Q83330",
                "url": "https://www.wikidata.org/wiki/Q83330",
                "license": "CC0 1.0"
            }
        },
        "research": {
            "vercy": "1.0-draft",
            "publication": {
                "status": "research-draft",
                "adjudicationStatus": "unreviewed",
                "publishableCanonical": false,
                "generatedAt": "2026-09-13T03:12:16Z",
                "providers": [
                    "Claude"
                ],
                "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
                "pass": 2,
                "wave": 3,
                "engine": "claude"
            },
            "metaModel": {
                "id": "THING-Q83330",
                "registryId": "vr.tr.lysosome",
                "name": "lysosome",
                "version": "0.2.0-wave.3",
                "entryKind": "thing",
                "family": "Thing Registry",
                "domain": [
                    "PHY.LIV"
                ],
                "status": "research-draft"
            },
            "canonicalUrl": "https://ver.cy/models/thing/q83330/",
            "model": {
                "registry_id": "vr.tr.lysosome",
                "name": "lysosome",
                "purpose": "Let an agent explain lysosomes and their functions, relay structure, formation and enzymes from cell biology references, describe lysosomal storage diseases in general terms, and distinguish lysosomes from related organelles.",
                "definition": "A membrane-bound organelle in animal cells containing acid hydrolases that digest macromolecules, worn-out organelles and material taken up by endocytosis and autophagy, formed from the Golgi apparatus as primary lysosomes and maturing into secondary lysosomes and endolysosomes after fusion with endosomes or autophagosomes, with specialised forms such as cytolytic granules in killer lymphocytes and mast cell granules; lysosomes act in recycling, signalling and nutrient sensing, and their defects cause lysosomal storage diseases.",
                "what_it_is_for": "Not applicable; a cell organelle.",
                "affordances": [
                    "explain structure and function",
                    "relay formation and enzymes",
                    "describe related diseases",
                    "distinguish from other organelles"
                ],
                "distinguishing_features": [
                    "Acidic lumen",
                    "Acid hydrolases",
                    "Degradation and recycling",
                    "Signalling role"
                ],
                "appearance": "Not a visible object; small dense vesicles seen by electron microscopy.",
                "visual_identification": [
                    "Acidic digestive organelle of animal cells",
                    "Primary and secondary lysosomes, endolysosomes, cytolytic and mast cell granules, megasomes",
                    "Peroxisomes handle oxidation; vacuoles are the plant and fungal equivalents; endosomes sort cargo"
                ],
                "physical_properties": [
                    {
                        "quantity": "internal pH",
                        "typical_range": "about 4.5-5",
                        "unit": "value",
                        "note": ""
                    },
                    {
                        "quantity": "diameter",
                        "typical_range": "about 0.1-1.2",
                        "unit": "micrometres",
                        "note": ""
                    },
                    {
                        "quantity": "acid hydrolases",
                        "typical_range": "about 60",
                        "unit": "count",
                        "note": ""
                    }
                ],
                "families_and_kinds": [
                    "primary lysosomes",
                    "secondary lysosomes and endolysosomes",
                    "autolysosomes",
                    "lysosome-related organelles such as cytolytic granules, mast cell granules and melanosomes",
                    "megasomes in some cells",
                    "lytic vacuoles in plants and fungi"
                ],
                "related_models": [
                    {
                        "relation": "is a kind of",
                        "target": "lytic vacuole",
                        "why": "in registry terms"
                    },
                    {
                        "relation": "is a kind of",
                        "target": "membranous cytoplasmic organelle",
                        "why": "in registry terms"
                    },
                    {
                        "relation": "is formed from",
                        "target": "Golgi apparatus",
                        "why": "and endosomes"
                    },
                    {
                        "relation": "is defective in",
                        "target": "lysosomal storage disease",
                        "why": "when enzymes are missing"
                    }
                ],
                "identifiers": [
                    {
                        "scheme": "GO",
                        "value_or_pattern": "GO:0005764",
                        "note": "lysosome"
                    },
                    {
                        "scheme": "MeSH",
                        "value_or_pattern": "D008247",
                        "note": "lysosomes"
                    }
                ],
                "standards_and_regulation": [
                    "No regulation; standard cell biology definitions",
                    "Clinical guidelines for lysosomal storage diseases"
                ],
                "failure_modes_and_hazards": [
                    "Confusing lysosomes with peroxisomes or vacuoles",
                    "Oversimplifying formation pathways",
                    "Agents giving personal medical advice about storage diseases"
                ],
                "in_scope": [],
                "out_of_scope": [],
                "characteristics": []
            },
            "sources": [],
            "structure": {
                "bundles": [
                    {
                        "id": "understand",
                        "name": "Understand",
                        "description": "What a lysosome is.",
                        "rationale": "Science.",
                        "layers": [
                            {
                                "id": "definition",
                                "name": "Definition",
                                "description": "Definition and structure.",
                                "findings": [
                                    {
                                        "id": "definition-finding",
                                        "name": "Definition",
                                        "description": "Definition.",
                                        "questions": [
                                            {
                                                "text": "What is a lysosome, and how do its membrane, proton pumps and enzymes work?",
                                                "kind": "definition"
                                            },
                                            {
                                                "text": "Is the question about lysosomes, peroxisomes, vacuoles or endosomes?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "kinds",
                                "name": "Kinds",
                                "description": "Kinds and formation.",
                                "findings": [
                                    {
                                        "id": "kinds-finding",
                                        "name": "Kinds",
                                        "description": "Kinds.",
                                        "questions": [
                                            {
                                                "text": "How do primary lysosomes, secondary lysosomes, endolysosomes and lysosome-related granules form and differ?",
                                                "kind": "definition"
                                            },
                                            {
                                                "text": "Which entry fits the specific kind?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "function",
                        "name": "Function",
                        "description": "Functions.",
                        "rationale": "Science.",
                        "layers": [
                            {
                                "id": "degradation",
                                "name": "Degradation",
                                "description": "Degradation and recycling.",
                                "findings": [
                                    {
                                        "id": "degradation-finding",
                                        "name": "Degradation",
                                        "description": "Degradation.",
                                        "questions": [
                                            {
                                                "text": "How do lysosomes digest material from endocytosis, phagocytosis and autophagy?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which references are standard?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "signalling",
                                "name": "Signalling",
                                "description": "Signalling and sensing.",
                                "findings": [
                                    {
                                        "id": "signalling-finding",
                                        "name": "Signalling",
                                        "description": "Signalling.",
                                        "questions": [
                                            {
                                                "text": "How do lysosomes act in nutrient sensing through mTOR, and in secretion and immunity?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which entry fits autophagy?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "disease",
                        "name": "Disease",
                        "description": "Disease.",
                        "rationale": "Clinical.",
                        "layers": [
                            {
                                "id": "storage",
                                "name": "Storage",
                                "description": "Lysosomal storage diseases.",
                                "findings": [
                                    {
                                        "id": "storage-finding",
                                        "name": "Storage",
                                        "description": "Storage.",
                                        "questions": [
                                            {
                                                "text": "What are lysosomal storage diseases such as Gaucher and Tay-Sachs, in general terms?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Is the user asking about their own or a family diagnosis, which needs a specialist?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "therapy",
                                "name": "Therapy",
                                "description": "Therapies and research.",
                                "findings": [
                                    {
                                        "id": "therapy-finding",
                                        "name": "Therapy",
                                        "description": "Therapy.",
                                        "questions": [
                                            {
                                                "text": "How do enzyme replacement and other therapies work, and what research targets lysosomes in cancer and neurodegeneration?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which sources are cited?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "context",
                        "name": "Context",
                        "description": "History and methods.",
                        "rationale": "Context.",
                        "layers": [
                            {
                                "id": "history",
                                "name": "History",
                                "description": "History.",
                                "findings": [
                                    {
                                        "id": "history-finding",
                                        "name": "History",
                                        "description": "History.",
                                        "questions": [
                                            {
                                                "text": "How did Christian de Duve discover lysosomes, and how has the field developed?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which entry fits the history of cell biology?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "methods",
                                "name": "Methods",
                                "description": "Methods.",
                                "findings": [
                                    {
                                        "id": "methods-finding",
                                        "name": "Methods",
                                        "description": "Methods.",
                                        "questions": [
                                            {
                                                "text": "How are lysosomes studied by microscopy, fractionation and markers?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "text": "Which entry fits cell fractionation?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "openQuestions": [
                "Should lysosomal storage disease and autophagy be separate primary entries?",
                "How should cell biology references be linked?",
                "The registry entry has merged aliases naming granules and stages; should they be split off?"
            ],
            "statistics": {
                "bundles": 4,
                "layers": 8,
                "findings": 8,
                "questions": 16
            }
        },
        "draft": {
            "generator": "vr.draft.v3",
            "status": "draft-generated",
            "researched": false,
            "archetype": "organism",
            "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.",
            "facetsInferred": true,
            "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.",
            "purpose": "Give an agent a durable, checkable way to recognise a lysosome, record what state it is in, and decide what may be done with it.",
            "whatItIs": "Let an agent explain lysosomes and their functions, relay structure, formation and enzymes from cell biology references, describe lysosomal storage diseases in general terms, and distinguish lysosomes from related organelles.",
            "characteristics": {
                "substance": "living",
                "origin": "natural",
                "agency": "autonomous",
                "mobility": "self-moving"
            },
            "whatYouCanDoWithIt": [
                "observed and measured"
            ],
            "distinguishingFeatures": [
                "Names folded into this entry, which a task may need to split apart again: mast cell granule, cytolytic granule, secondary lysosome, endolysosome, primary lysosome, megasome, Lysosome of muscle cell.",
                "9 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.",
                "Described in 76 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is."
            ],
            "openQuestionsForResearch": [
                "Which of the bundles below does a real task actually need, and which are ceremony?",
                "What does this thing have that the facets do not capture at all?",
                "Which neighbouring kind is most often confused with a lysosome, and on what evidence are they told apart?"
            ],
            "whatItIsMadeOf": "a living thing",
            "physicalCharacter": [
                "Moves under its own power or of its own accord.",
                "Acts on its own behalf.",
                "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing."
            ],
            "whatCanBeDoneWithIt": [
                "observe it, measure it, record its state"
            ],
            "howItIsRecognised": [
                "Recognised by diagnostic characters, and those differ by life stage - the young of many kinds are mistaken for other kinds entirely. A sighting is settled by characters, a photograph and a place, not by a name alone."
            ],
            "relatedModels": [
                {
                    "relation": "covers",
                    "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.",
                    "targets": [
                        "mast cell granule",
                        "cytolytic granule",
                        "secondary lysosome",
                        "endolysosome",
                        "primary lysosome",
                        "megasome",
                        "Lysosome of muscle cell"
                    ]
                }
            ],
            "standing": "Described in 76 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 9 finer distinctions are held inside this entry as names rather than as separate models.",
            "structure": {
                "bundles": [
                    {
                        "id": "identity-and-classification",
                        "name": "Identity, naming and classification",
                        "description": "How an agent tells one lysosome from another, and a lysosome from things that resemble it.",
                        "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.",
                        "layers": [
                            {
                                "id": "naming-and-identifiers",
                                "name": "Names and identifiers",
                                "description": "The names this thing goes by and the identifiers that survive translation and time.",
                                "findings": [
                                    {
                                        "id": "preferred-name-and-aliases",
                                        "name": "Preferred name, aliases and local names",
                                        "description": "Which name to use, which names mean the same thing, and which merely sound similar.",
                                        "questions": [
                                            {
                                                "id": "preferred-name-and-aliases-q01",
                                                "text": "What identifies and describes the name of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q02",
                                                "text": "Who or what asserted this about the name of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "preferred-name-and-aliases-q03",
                                                "text": "What may an agent decide or do once the name of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "stable-identifiers",
                                        "name": "Stable identifiers and external keys",
                                        "description": "Identifiers that keep pointing at this kind of thing across systems and languages.",
                                        "questions": [
                                            {
                                                "id": "stable-identifiers-q01",
                                                "text": "What identifies and describes an identifier for a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q02",
                                                "text": "Who or what asserted this about an identifier for a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stable-identifiers-q03",
                                                "text": "What may an agent decide or do once an identifier for a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "classification-and-granularity",
                                "name": "Classification and granularity",
                                "description": "Where a lysosome sits among kinds, and how finely a task needs to cut it.",
                                "findings": [
                                    {
                                        "id": "kind-and-parents",
                                        "name": "Kind, parents and neighbouring kinds",
                                        "description": "The classes this thing belongs to and the ones it is next to.",
                                        "questions": [
                                            {
                                                "id": "kind-and-parents-q01",
                                                "text": "What identifies and describes the kind of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q02",
                                                "text": "Who or what asserted this about the kind of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "kind-and-parents-q03",
                                                "text": "What may an agent decide or do once the kind of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    },
                                    {
                                        "id": "distinguishing-features",
                                        "name": "Distinguishing features",
                                        "description": "What separates a lysosome from the things most often confused with it.",
                                        "questions": [
                                            {
                                                "id": "distinguishing-features-q01",
                                                "text": "What identifies and describes what distinguishes a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q02",
                                                "text": "Who or what asserted this about what distinguishes a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "distinguishing-features-q03",
                                                "text": "What may an agent decide or do once what distinguishes a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "form-and-composition",
                        "name": "Form, composition and condition",
                        "description": "What a lysosome is made of, what shape and size it takes, and what state it is in.",
                        "rationale": "A physical thing can be measured, and a model that cannot record its measurements cannot support any decision that depends on them.",
                        "layers": [
                            {
                                "id": "form-and-dimensions",
                                "name": "Form and dimensions",
                                "description": "Shape, size, mass and the ranges these take across examples.",
                                "findings": [
                                    {
                                        "id": "measurable-dimensions",
                                        "name": "Measurable dimensions and their units",
                                        "description": "The quantities worth recording and the units they are recorded in.",
                                        "questions": [
                                            {
                                                "id": "measurable-dimensions-q01",
                                                "text": "What identifies and describes the dimensions of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "measurable-dimensions-q02",
                                                "text": "Who or what asserted this about the dimensions of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "measurable-dimensions-q03",
                                                "text": "What may an agent decide or do once the dimensions of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "material-and-composition",
                                "name": "Material and composition",
                                "description": "Anatomy, parts and life stage.",
                                "findings": [
                                    {
                                        "id": "parts-and-materials",
                                        "name": "Parts and life stages",
                                        "description": "The parts of a lysosome and the stages it passes through.",
                                        "questions": [
                                            {
                                                "id": "parts-and-materials-q01",
                                                "text": "What identifies and describes the composition of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "parts-and-materials-q02",
                                                "text": "Who or what asserted this about the composition of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "parts-and-materials-q03",
                                                "text": "What may an agent decide or do once the composition of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "condition-and-integrity",
                                "name": "Condition and integrity",
                                "description": "Wear, damage, health and the difference between working and broken.",
                                "findings": [
                                    {
                                        "id": "condition-assessment",
                                        "name": "Condition, damage and health",
                                        "description": "How the condition of a lysosome is judged and by whom.",
                                        "questions": [
                                            {
                                                "id": "condition-assessment-q01",
                                                "text": "What identifies and describes the condition of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "condition-assessment-q02",
                                                "text": "Who or what asserted this about the condition of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "condition-assessment-q03",
                                                "text": "What may an agent decide or do once the condition of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "place-and-movement",
                        "name": "Place and movement",
                        "description": "Where a lysosome is, how it got there and where it may go (self-moving).",
                        "rationale": "A thing that can move needs its position recorded with a time, or every later claim about it is about a place it has left.",
                        "layers": [
                            {
                                "id": "location-and-placement",
                                "name": "Location and placement",
                                "description": "Position, containment and the reference frame the position is given in.",
                                "findings": [
                                    {
                                        "id": "position-and-frame",
                                        "name": "Position, container and reference frame",
                                        "description": "Where a lysosome is, and what that position is measured against.",
                                        "questions": [
                                            {
                                                "id": "position-and-frame-q01",
                                                "text": "What identifies and describes the location of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "position-and-frame-q02",
                                                "text": "Who or what asserted this about the location of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "position-and-frame-q03",
                                                "text": "What may an agent decide or do once the location of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "movement-and-transfer",
                                "name": "Movement and transfer",
                                "description": "How a lysosome moves on its own.",
                                "findings": [
                                    {
                                        "id": "movement-events",
                                        "name": "Movement events and constraints",
                                        "description": "What counts as a movement, what records it and what limits it.",
                                        "questions": [
                                            {
                                                "id": "movement-events-q01",
                                                "text": "What identifies and describes the movement of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "movement-events-q02",
                                                "text": "Who or what asserted this about the movement of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "movement-events-q03",
                                                "text": "What may an agent decide or do once the movement of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "state-and-lifecycle",
                        "name": "State and lifecycle",
                        "description": "The states a lysosome passes through and the events that move it between them.",
                        "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.",
                        "layers": [
                            {
                                "id": "lifecycle-stages",
                                "name": "Lifecycle stages",
                                "description": "From coming into existence to ceasing to be one of these.",
                                "findings": [
                                    {
                                        "id": "stages-and-transitions",
                                        "name": "Stages and transitions",
                                        "description": "The stages worth naming and what moves a lysosome between them.",
                                        "questions": [
                                            {
                                                "id": "stages-and-transitions-q01",
                                                "text": "What identifies and describes the lifecycle of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q02",
                                                "text": "Who or what asserted this about the lifecycle of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "stages-and-transitions-q03",
                                                "text": "What may an agent decide or do once the lifecycle of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "observations-and-status",
                                "name": "Observations and current status",
                                "description": "What is observed about a lysosome, how often and by whom.",
                                "findings": [
                                    {
                                        "id": "observation-record",
                                        "name": "Observation record",
                                        "description": "How an observation of a lysosome is recorded so that it can be superseded rather than overwritten.",
                                        "questions": [
                                            {
                                                "id": "observation-record-q01",
                                                "text": "What identifies and describes an observation of a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q02",
                                                "text": "Who or what asserted this about an observation of a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "observation-record-q03",
                                                "text": "What may an agent decide or do once an observation of a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "taxonomic-placement",
                        "name": "Taxonomic placement and identification",
                        "description": "What lysosome is called scientifically, by whose authority, and how a specimen is recognised.",
                        "rationale": "Names change with revisions while the organism does not, so a name without its authority and date cannot be reconciled later.",
                        "layers": [
                            {
                                "id": "accepted-name",
                                "name": "Accepted name and synonymy",
                                "description": "The current binomial, its author and date, and the names it replaced.",
                                "findings": [
                                    {
                                        "id": "name-and-authority",
                                        "name": "Accepted name, authority and synonyms",
                                        "description": "What to record so a later revision can be applied without losing the old data.",
                                        "questions": [
                                            {
                                                "id": "name-and-authority-q01",
                                                "text": "What is the accepted scientific name of lysosome, with its author and year, and which synonyms does it absorb?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "name-and-authority-q02",
                                                "text": "Which taxonomic authority is being followed, and what would a competing authority say?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "field-identification",
                                "name": "Field identification",
                                "description": "The characters that separate lysosome from what it is confused with.",
                                "findings": [
                                    {
                                        "id": "diagnostic-characters",
                                        "name": "Diagnostic characters and confusable kinds",
                                        "description": "Features that settle an identification, and those that only suggest it.",
                                        "questions": [
                                            {
                                                "id": "diagnostic-characters-q01",
                                                "text": "Which observable characters distinguish lysosome from its closest look-alikes, and at which life stage are they visible?",
                                                "kind": "boundary"
                                            },
                                            {
                                                "id": "diagnostic-characters-q02",
                                                "text": "What evidence is enough to record an identification as confirmed rather than provisional?",
                                                "kind": "provenance"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "life-cycle-and-condition",
                        "name": "Life stages, condition and behaviour",
                        "description": "What lysosome does over its life and how its state is judged.",
                        "rationale": "Stage and condition change what may be done - handled, treated, harvested, left alone - and both are observations with a time.",
                        "layers": [
                            {
                                "id": "stages-and-reproduction",
                                "name": "Stages and reproduction",
                                "description": "Development from origin to death, including forms that look like different animals.",
                                "findings": [
                                    {
                                        "id": "life-stages",
                                        "name": "Life stages and their marks",
                                        "description": "The stages worth recording and what tells them apart.",
                                        "questions": [
                                            {
                                                "id": "life-stages-q01",
                                                "text": "What stages does lysosome pass through, and what observable change marks each transition?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "life-stages-q02",
                                                "text": "Which stages are so unlike the adult that they are mistaken for another kind?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "health-and-condition",
                                "name": "Health and condition",
                                "description": "How condition is assessed and by whom.",
                                "findings": [
                                    {
                                        "id": "condition-assessment",
                                        "name": "Condition assessment",
                                        "description": "Signs of health, injury and stress, and who is competent to judge them.",
                                        "questions": [
                                            {
                                                "id": "condition-assessment-q01",
                                                "text": "How is the condition of lysosome judged, on what scale, and by whom?",
                                                "kind": "measurement"
                                            },
                                            {
                                                "id": "condition-assessment-q02",
                                                "text": "What condition obliges an agent to act, and what act is permitted to whom?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "range-and-status",
                        "name": "Habitat, range and conservation status",
                        "description": "Where lysosome lives and how threatened it is.",
                        "rationale": "Range and status govern what is lawful, and both are assessments with an assessor and a year rather than facts of nature.",
                        "layers": [
                            {
                                "id": "habitat-and-range",
                                "name": "Habitat and range",
                                "description": "Native range, introductions and the habitat it needs.",
                                "findings": [
                                    {
                                        "id": "range-record",
                                        "name": "Range, introductions and habitat",
                                        "description": "What to record about where it is found and how it got there.",
                                        "questions": [
                                            {
                                                "id": "range-record-q01",
                                                "text": "What is the native range of lysosome, where has it been introduced, and what habitat does it require?",
                                                "kind": "definition"
                                            },
                                            {
                                                "id": "range-record-q02",
                                                "text": "What distinguishes a native record from an introduced or vagrant one?",
                                                "kind": "boundary"
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "protection-status",
                                "name": "Protection and legal status",
                                "description": "Conservation assessments and the rules that follow from them.",
                                "findings": [
                                    {
                                        "id": "status-and-rules",
                                        "name": "Conservation status and legal consequence",
                                        "description": "The assessment, its date, and what it forbids or requires where.",
                                        "questions": [
                                            {
                                                "id": "status-and-rules-q01",
                                                "text": "What conservation status does lysosome hold, under which assessment and year?",
                                                "kind": "provenance"
                                            },
                                            {
                                                "id": "status-and-rules-q02",
                                                "text": "What does that status forbid or require of an agent, and in which jurisdiction?",
                                                "kind": "action"
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    },
                    {
                        "id": "provenance-and-evidence",
                        "name": "Provenance, evidence and time",
                        "description": "Where every claim about a lysosome came from and when it held.",
                        "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.",
                        "layers": [
                            {
                                "id": "source-and-authority",
                                "name": "Source and authority",
                                "description": "Who said it, on what evidence, and how strongly.",
                                "findings": [
                                    {
                                        "id": "claim-provenance",
                                        "name": "Claim provenance and confidence",
                                        "description": "The authority behind each claim about a lysosome and how confident it is.",
                                        "questions": [
                                            {
                                                "id": "claim-provenance-q01",
                                                "text": "What identifies and describes a claim about a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q02",
                                                "text": "Who or what asserted this about a claim about a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "claim-provenance-q03",
                                                "text": "What may an agent decide or do once a claim about a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            },
                            {
                                "id": "time-and-versions",
                                "name": "Time, versions and supersession",
                                "description": "When a claim was true, when it was learnt, and what replaced it.",
                                "findings": [
                                    {
                                        "id": "validity-and-supersession",
                                        "name": "Validity period and supersession",
                                        "description": "How an old claim about a lysosome is retired without being erased.",
                                        "questions": [
                                            {
                                                "id": "validity-and-supersession-q01",
                                                "text": "What identifies and describes the validity of a claim about a lysosome, and in what units or vocabulary?",
                                                "kind": "definition",
                                                "answer_data": [
                                                    "identifiers",
                                                    "types and classes",
                                                    "values with units",
                                                    "explicit unknowns"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q02",
                                                "text": "Who or what asserted this about the validity of a claim about a lysosome, by which method, and when was it true?",
                                                "kind": "provenance",
                                                "answer_data": [
                                                    "authority",
                                                    "method",
                                                    "evidence",
                                                    "event time",
                                                    "knowledge time"
                                                ]
                                            },
                                            {
                                                "id": "validity-and-supersession-q03",
                                                "text": "What may an agent decide or do once the validity of a claim about a lysosome is known, and what must it refuse?",
                                                "kind": "action",
                                                "answer_data": [
                                                    "permitted actions",
                                                    "preconditions",
                                                    "refusals",
                                                    "escalation"
                                                ]
                                            }
                                        ]
                                    }
                                ]
                            }
                        ]
                    }
                ]
            },
            "statistics": {
                "bundles": 8,
                "layers": 17,
                "findings": 19,
                "questions": 51
            }
        }
    }
}