{ "model": { "rank": 12695, "code": "thing-q849491", "model_id": "vr.tr.neuroplasticity", "name": "neuroplasticity", "purpose": "Let an agent explain neuroplasticity and its mechanisms, relay research on learning, development and recovery with attribution, distinguish established science from popular overclaims, and route clinical questions to professionals.", "family": "Thing Registry", "category": "Activities and processes", "status": "research-draft", "kind": "thing", "plane": "ACT", "domain": "ACT.PRC", "industry": "", "version": "", "url": "/models/thing/q849491/", "tier": 2, "score": 39, "payload": { "layer": "wikidata", "aliases": [ "long-term depression", "synaptic plasticity", "neuronal sensitization", "homeostatic plasticity", "spike-timing-dependent plasticity", "Post-tetanic potentiation" ], "aliasCount": 6, "merged": 6, "knownIn": 39, "facets": null, "markers": [], "lexicalClass": "", "senseRank": null, "alsoRegisteredAs": null, "source": { "dataset": "wikidata", "item": "Q849491", "url": "https://www.wikidata.org/wiki/Q849491", "license": "CC0 1.0" } }, "research": { "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-13T00:32:31Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude" }, "metaModel": { "id": "THING-Q849491", "registryId": "vr.tr.neuroplasticity", "name": "neuroplasticity", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "ACT.PRC" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q849491/", "model": { "registry_id": "vr.tr.neuroplasticity", "name": "neuroplasticity", "purpose": "Let an agent explain neuroplasticity and its mechanisms, relay research on learning, development and recovery with attribution, distinguish established science from popular overclaims, and route clinical questions to professionals.", "definition": "The ability of the nervous system to change its structure and function in response to experience, injury and development, through mechanisms including synaptic plasticity such as long-term potentiation and long-term depression, spike-timing-dependent plasticity, post-tetanic potentiation, homeostatic plasticity, neuronal sensitisation, changes in cortical maps and, in some regions, adult neurogenesis; neuroplasticity underlies learning, memory and recovery after brain injury and is a focus of rehabilitation and education.", "what_it_is_for": "Not applicable; a biological process.", "affordances": [ "explain mechanisms and levels", "relay research on learning and recovery", "distinguish science from overclaims", "route clinical questions" ], "distinguishing_features": [ "Experience-dependent change", "Multiple mechanisms and timescales", "Critical periods", "Basis of learning and recovery" ], "appearance": "Not visible; changes in synapses and circuits shown in experiments and imaging.", "visual_identification": [ "Nervous system change with experience", "Synaptic, structural and map plasticity", "Neurogenesis is the birth of new neurons, one contributor; brain training claims are separate" ], "physical_properties": [], "families_and_kinds": [ "synaptic plasticity: long-term potentiation and depression, spike-timing-dependent plasticity, post-tetanic potentiation", "homeostatic plasticity", "structural plasticity and dendritic changes", "cortical map plasticity", "sensitisation and habituation", "developmental plasticity and critical periods", "adult neurogenesis" ], "related_models": [ { "relation": "is a kind of", "target": "biological process", "why": "in registry terms" }, { "relation": "underlies", "target": "learning", "why": "and memory" }, { "relation": "is studied by", "target": "neuroscience", "why": "the field" }, { "relation": "is exploited in", "target": "neurorehabilitation", "why": "after injury" } ], "identifiers": [], "standards_and_regulation": [ "Clinical guidelines for stroke and brain injury rehabilitation", "Advertising rules affecting brain training claims" ], "failure_modes_and_hazards": [ "Overclaiming in popular media and products", "Maladaptive plasticity such as chronic pain and tinnitus", "Agents giving personal clinical advice" ], "in_scope": [], "out_of_scope": [], "characteristics": [] }, "sources": [], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What neuroplasticity is.", "rationale": "Science.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition and levels.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is neuroplasticity, and at what levels does it occur?", "kind": "definition" }, { "text": "Is the question about established mechanisms or a popular claim?", "kind": "boundary" } ] } ] }, { "id": "mechanisms", "name": "Mechanisms", "description": "Mechanisms.", "findings": [ { "id": "mechanisms-finding", "name": "Mechanisms", "description": "Mechanisms.", "questions": [ { "text": "How do long-term potentiation, long-term depression, spike-timing-dependent and homeostatic plasticity work?", "kind": "definition" }, { "text": "Which entry fits the specific mechanism?", "kind": "action" } ] } ] } ] }, { "id": "function", "name": "Function", "description": "Learning and development.", "rationale": "Attribution.", "layers": [ { "id": "learning", "name": "Learning", "description": "Learning and memory.", "findings": [ { "id": "learning-finding", "name": "Learning", "description": "Learning.", "questions": [ { "text": "How does plasticity underlie learning and memory, as research shows?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] }, { "id": "development", "name": "Development", "description": "Development and critical periods.", "findings": [ { "id": "development-finding", "name": "Development", "description": "Development.", "questions": [ { "text": "How does plasticity change across development and ageing, including critical periods?", "kind": "provenance" }, { "text": "Which entry fits critical period?", "kind": "action" } ] } ] } ] }, { "id": "clinical", "name": "Clinical", "description": "Injury and rehabilitation.", "rationale": "Clinical.", "layers": [ { "id": "recovery", "name": "Recovery", "description": "Recovery after injury.", "findings": [ { "id": "recovery-finding", "name": "Recovery", "description": "Recovery.", "questions": [ { "text": "How does plasticity support recovery after stroke and injury, and how is it used in rehabilitation, per guidelines?", "kind": "provenance" }, { "text": "Is the user asking about their own recovery, which needs a clinician?", "kind": "boundary" } ] } ] }, { "id": "maladaptive", "name": "Maladaptive", "description": "Maladaptive plasticity.", "findings": [ { "id": "maladaptive-finding", "name": "Maladaptive", "description": "Maladaptive.", "questions": [ { "text": "How can plasticity contribute to chronic pain, tinnitus and addiction, as research describes?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Claims and history.", "rationale": "Context.", "layers": [ { "id": "claims", "name": "Claims", "description": "Popular claims.", "findings": [ { "id": "claims-finding", "name": "Claims", "description": "Claims.", "questions": [ { "text": "What does evidence say about brain training and other neuroplasticity products, with findings attributed?", "kind": "provenance" }, { "text": "Is the presentation free of overclaims?", "kind": "boundary" } ] } ] }, { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How did the concept develop from Ramon y Cajal and Hebb to Merzenich and modern imaging?", "kind": "provenance" }, { "text": "Which entry fits the history of neuroscience?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should synaptic plasticity be a separate primary entry?", "How should neuroscience references be linked?", "The registry entry has merged aliases naming specific mechanisms; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }, "draft": { "generator": "vr.draft.v3", "status": "draft-generated", "researched": false, "archetype": "abstract concept", "method": "Written from the archetype playbook - what this kind of thing needs beyond identity and provenance - and from the structure that recurred across 6,333 models already researched by two engines. Applied to this entry by rule. No source was read for this thing and no claim here is researched. This entry carries no facets of its own, so they were inferred from its domain - a guess about a whole domain applied to one thing.", "facetsInferred": true, "nextPass": "A researcher replaces this draft with a sourced specification. Treat every sentence below as a proposal to argue with.", "purpose": "Give an agent a durable, checkable way to recognise a neuroplasticity, record what state it is in, and decide what may be done with it.", "whatItIs": "Let an agent explain neuroplasticity and its mechanisms, relay research on learning, development and recovery with attribution, distinguish established science from popular overclaims, and route clinical questions to professionals.", "characteristics": { "substance": "activity", "origin": "conceptual", "agency": "inert" }, "whatYouCanDoWithIt": [ "observed and measured" ], "distinguishingFeatures": [ "Names folded into this entry, which a task may need to split apart again: long-term depression, synaptic plasticity, neuronal sensitization, homeostatic plasticity, spike-timing-dependent plasticity, Post-tetanic potentiation.", "6 finer distinctions are held as aliases rather than separate entries, because telling them apart needs a task that asks for it.", "Described in 39 Wikipedia languages, which is a measure of how widely the thing is known, not of how important it is." ], "openQuestionsForResearch": [ "Which of the bundles below does a real task actually need, and which are ceremony?", "What does this thing have that the facets do not capture at all?", "Which neighbouring kind is most often confused with a neuroplasticity, and on what evidence are they told apart?" ], "whatItIsMadeOf": "something that happens over time", "physicalCharacter": [ "Does nothing on its own; everything it does, something else did to it.", "These come from the domain this entry sits in rather than from the entry itself, so treat them as a first guess about the whole domain applied to one thing." ], "whatCanBeDoneWithIt": [ "observe it, measure it, record its state" ], "howItIsRecognised": [ "Nothing to see. What is recognised is an instance of it, and which instances count is exactly what is argued about." ], "relatedModels": [ { "relation": "covers", "note": "Finer kinds folded into this entry because telling them apart needs a task that asks for it. Each is a model waiting to be split out when one does.", "targets": [ "long-term depression", "synaptic plasticity", "neuronal sensitization", "homeostatic plasticity", "spike-timing-dependent plasticity", "Post-tetanic potentiation" ] } ], "standing": "Described in 39 Wikipedia languages, which measures how widely it is written about rather than how important or how common it is. 6 finer distinctions are held inside this entry as names rather than as separate models.", "structure": { "bundles": [ { "id": "identity-and-classification", "name": "Identity, naming and classification", "description": "How an agent tells one neuroplasticity from another, and a neuroplasticity from things that resemble it.", "rationale": "Recognition comes before every other claim. Without stable identity nothing else in the model can be trusted to be about the same thing twice.", "layers": [ { "id": "naming-and-identifiers", "name": "Names and identifiers", "description": "The names this thing goes by and the identifiers that survive translation and time.", "findings": [ { "id": "preferred-name-and-aliases", "name": "Preferred name, aliases and local names", "description": "Which name to use, which names mean the same thing, and which merely sound similar.", "questions": [ { "id": "preferred-name-and-aliases-q01", "text": "What identifies and describes the name of a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "preferred-name-and-aliases-q02", "text": "Who or what asserted this about the name of a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "preferred-name-and-aliases-q03", "text": "What may an agent decide or do once the name of a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "stable-identifiers", "name": "Stable identifiers and external keys", "description": "Identifiers that keep pointing at this kind of thing across systems and languages.", "questions": [ { "id": "stable-identifiers-q01", "text": "What identifies and describes an identifier for a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stable-identifiers-q02", "text": "Who or what asserted this about an identifier for a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stable-identifiers-q03", "text": "What may an agent decide or do once an identifier for a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "classification-and-granularity", "name": "Classification and granularity", "description": "Where a neuroplasticity sits among kinds, and how finely a task needs to cut it.", "findings": [ { "id": "kind-and-parents", "name": "Kind, parents and neighbouring kinds", "description": "The classes this thing belongs to and the ones it is next to.", "questions": [ { "id": "kind-and-parents-q01", "text": "What identifies and describes the kind of a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "kind-and-parents-q02", "text": "Who or what asserted this about the kind of a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "kind-and-parents-q03", "text": "What may an agent decide or do once the kind of a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] }, { "id": "distinguishing-features", "name": "Distinguishing features", "description": "What separates a neuroplasticity from the things most often confused with it.", "questions": [ { "id": "distinguishing-features-q01", "text": "What identifies and describes what distinguishes a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "distinguishing-features-q02", "text": "Who or what asserted this about what distinguishes a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "distinguishing-features-q03", "text": "What may an agent decide or do once what distinguishes a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "state-and-lifecycle", "name": "State and lifecycle", "description": "The states a neuroplasticity passes through and the events that move it between them.", "rationale": "Most decisions about a thing depend on what state it is in now, which is a claim with a time on it, not a property.", "layers": [ { "id": "lifecycle-stages", "name": "Lifecycle stages", "description": "From coming into existence to ceasing to be one of these.", "findings": [ { "id": "stages-and-transitions", "name": "Stages and transitions", "description": "The stages worth naming and what moves a neuroplasticity between them.", "questions": [ { "id": "stages-and-transitions-q01", "text": "What identifies and describes the lifecycle of a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "stages-and-transitions-q02", "text": "Who or what asserted this about the lifecycle of a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "stages-and-transitions-q03", "text": "What may an agent decide or do once the lifecycle of a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "observations-and-status", "name": "Observations and current status", "description": "What is observed about a neuroplasticity, how often and by whom.", "findings": [ { "id": "observation-record", "name": "Observation record", "description": "How an observation of a neuroplasticity is recorded so that it can be superseded rather than overwritten.", "questions": [ { "id": "observation-record-q01", "text": "What identifies and describes an observation of a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "observation-record-q02", "text": "Who or what asserted this about an observation of a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "observation-record-q03", "text": "What may an agent decide or do once an observation of a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "process-and-outcome", "name": "Process, inputs and outcome", "description": "How a neuroplasticity proceeds, what it needs and what it leaves behind.", "rationale": "An activity is known by its steps and its results, and both have to be recordable while it is still running.", "layers": [ { "id": "steps-and-sequence", "name": "Steps and sequence", "description": "The steps of a neuroplasticity, their order and what may run in parallel.", "findings": [ { "id": "steps-and-preconditions", "name": "Steps, preconditions and completion", "description": "What has to be true before each step of a neuroplasticity and what marks it done.", "questions": [ { "id": "steps-and-preconditions-q01", "text": "What identifies and describes a step of a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "steps-and-preconditions-q02", "text": "Who or what asserted this about a step of a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "steps-and-preconditions-q03", "text": "What may an agent decide or do once a step of a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "inputs-and-results", "name": "Inputs, resources and results", "description": "What a neuroplasticity consumes and what it produces.", "findings": [ { "id": "inputs-and-outputs", "name": "Inputs, outputs and side effects", "description": "The resources a neuroplasticity takes and the results it leaves, wanted or not.", "questions": [ { "id": "inputs-and-outputs-q01", "text": "What identifies and describes the inputs and results of a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "inputs-and-outputs-q02", "text": "Who or what asserted this about the inputs and results of a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "inputs-and-outputs-q03", "text": "What may an agent decide or do once the inputs and results of a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] }, { "id": "definitions-in-contest", "name": "Definitions and who holds them", "description": "What neuroplasticity is taken to mean, and by whom.", "rationale": "When a field disagrees about a concept, the disagreement is the content. A model that picks one definition silently destroys the information.", "layers": [ { "id": "competing-definitions", "name": "Competing definitions", "description": "The main readings and the traditions behind them.", "findings": [ { "id": "definition-map", "name": "Definitions and their holders", "description": "Each definition with the school or body that holds it.", "questions": [ { "id": "definition-map-q01", "text": "Which definitions of neuroplasticity are in use, and which tradition or body holds each?", "kind": "definition" }, { "id": "definition-map-q02", "text": "What turns on the difference between them in practice?", "kind": "boundary" } ] } ] }, { "id": "operationalisation", "name": "Operationalisation", "description": "How it is measured or applied when it has to be.", "findings": [ { "id": "operational-record", "name": "Measures and proxies", "description": "Instruments and indicators used to stand in for it.", "questions": [ { "id": "operational-record-q01", "text": "How is neuroplasticity operationalised or measured in practice, and by what instrument?", "kind": "measurement" }, { "id": "operational-record-q02", "text": "What does that operationalisation leave out, and when does that matter?", "kind": "boundary" } ] } ] } ] }, { "id": "instances-and-use", "name": "Instances, use and consequence", "description": "What counts as an instance of neuroplasticity and what follows from calling something that.", "rationale": "Applying a concept is an act with consequences, so a model must say what the label licenses and what it does not.", "layers": [ { "id": "instances", "name": "What counts as an instance", "description": "Clear cases, borderline cases and non-cases.", "findings": [ { "id": "instance-tests", "name": "Tests for an instance", "description": "What would settle whether something falls under it.", "questions": [ { "id": "instance-tests-q01", "text": "What would settle whether something is an instance of neuroplasticity?", "kind": "boundary" }, { "id": "instance-tests-q02", "text": "Which borderline cases are argued about, and on what grounds?", "kind": "definition" } ] } ] }, { "id": "consequence", "name": "Consequence of application", "description": "Rights, duties or decisions that follow from the label.", "findings": [ { "id": "consequence-record", "name": "What the label licenses", "description": "What an agent may do once something is classified this way.", "questions": [ { "id": "consequence-record-q01", "text": "What follows practically once something is treated as neuroplasticity?", "kind": "action" }, { "id": "consequence-record-q02", "text": "What must an agent not infer from the label alone?", "kind": "action" } ] } ] } ] }, { "id": "provenance-and-evidence", "name": "Provenance, evidence and time", "description": "Where every claim about a neuroplasticity came from and when it held.", "rationale": "A claim without a source and a time cannot be superseded, only overwritten, and an agent that overwrites loses the ability to explain itself.", "layers": [ { "id": "source-and-authority", "name": "Source and authority", "description": "Who said it, on what evidence, and how strongly.", "findings": [ { "id": "claim-provenance", "name": "Claim provenance and confidence", "description": "The authority behind each claim about a neuroplasticity and how confident it is.", "questions": [ { "id": "claim-provenance-q01", "text": "What identifies and describes a claim about a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "claim-provenance-q02", "text": "Who or what asserted this about a claim about a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "claim-provenance-q03", "text": "What may an agent decide or do once a claim about a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] }, { "id": "time-and-versions", "name": "Time, versions and supersession", "description": "When a claim was true, when it was learnt, and what replaced it.", "findings": [ { "id": "validity-and-supersession", "name": "Validity period and supersession", "description": "How an old claim about a neuroplasticity is retired without being erased.", "questions": [ { "id": "validity-and-supersession-q01", "text": "What identifies and describes the validity of a claim about a neuroplasticity, and in what units or vocabulary?", "kind": "definition", "answer_data": [ "identifiers", "types and classes", "values with units", "explicit unknowns" ] }, { "id": "validity-and-supersession-q02", "text": "Who or what asserted this about the validity of a claim about a neuroplasticity, by which method, and when was it true?", "kind": "provenance", "answer_data": [ "authority", "method", "evidence", "event time", "knowledge time" ] }, { "id": "validity-and-supersession-q03", "text": "What may an agent decide or do once the validity of a claim about a neuroplasticity is known, and what must it refuse?", "kind": "action", "answer_data": [ "permitted actions", "preconditions", "refusals", "escalation" ] } ] } ] } ] } ] }, "statistics": { "bundles": 6, "layers": 12, "findings": 14, "questions": 38 } } } }