{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-11T06:19:07Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 1,
    "engine": "claude",
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-05T16:30:00Z",
      "ingestedAt": "2026-10-05T13:18:05+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "owners"
      ]
    },
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-06T19:51:53+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q1057",
    "registryId": "vr.tr.metabolism",
    "name": "metabolism",
    "version": "0.2.0-wave.1",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "ACT.PRC"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q1057/",
  "model": {
    "registry_id": "vr.tr.metabolism",
    "name": "metabolism",
    "purpose": "Let an agent explain metabolism accurately, separate scientific facts from diet marketing, and direct individual metabolic health questions to clinicians.",
    "definition": "The set of chemical reactions in living organisms that convert food into energy and building blocks, and eliminate waste, including catabolism and anabolism.",
    "what_it_is_for": "Metabolism keeps organisms alive; understanding it informs nutrition, medicine and biotechnology.",
    "affordances": [
      "study it in biochemistry",
      "measure metabolic rate",
      "diagnose metabolic disorders, by clinicians",
      "engineer it in biotechnology"
    ],
    "distinguishing_features": [
      "All chemical reactions of life",
      "Catabolism breaks down; anabolism builds up",
      "Regulated by enzymes and hormones",
      "Popular claims about boosting metabolism are often unsupported"
    ],
    "appearance": "Not visible; measured through energy use, blood tests and biochemical assays.",
    "visual_identification": [
      "Metabolic pathways in diagrams",
      "Basal metabolic rate measurements",
      "Metabolic disorders named in medicine"
    ],
    "physical_properties": [
      {
        "quantity": "adult basal metabolic rate",
        "typical_range": "about 1200-2000",
        "unit": "kcal per day",
        "note": "varies with body size and sex"
      }
    ],
    "families_and_kinds": [
      "energy metabolism",
      "carbohydrate, lipid and protein metabolism",
      "drug metabolism",
      "inborn errors of metabolism"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "biological process",
        "why": "process"
      },
      {
        "relation": "uses",
        "target": "protein",
        "why": "enzymes"
      },
      {
        "relation": "produces",
        "target": "energy",
        "why": "ATP"
      },
      {
        "relation": "can be disrupted by",
        "target": "autosomal recessive disease",
        "why": "metabolic disorders"
      }
    ],
    "identifiers": [
      {
        "scheme": "KEGG pathway id",
        "value_or_pattern": "map plus digits",
        "note": "metabolic pathways"
      },
      {
        "scheme": "GO biological process",
        "value_or_pattern": "GO:0008152",
        "note": "metabolic process"
      }
    ],
    "standards_and_regulation": [
      "Health claims regulation for foods such as EU Regulation 1924/2006"
    ],
    "failure_modes_and_hazards": [
      "Unsupported diet claims",
      "Individual medical advice",
      "Oversimplifying metabolic disease"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": [],
    "agent_conduct": {
      "may": [
        "Explain metabolism and its pathways from established sources.",
        "Help a person track diet and activity data they choose to share."
      ],
      "must_not": [
        "Promise to change a person's metabolism through products or regimes without evidence.",
        "Recommend extreme diets, fasting or supplements without medical supervision.",
        "Diagnose a metabolic disorder or adjust treatment such as insulin.",
        "Use metabolic or body data to shame or discriminate against a person."
      ],
      "requires_human": [
        "Changing medication or nutrition for a person with a metabolic disease."
      ]
    },
    "ethics": {
      "considerations": [
        "Claims about metabolism are widely used to sell ineffective or harmful weight-loss products.",
        "Body and health data are sensitive and can stigmatize people."
      ],
      "affected_parties": [
        "People seeking health advice",
        "People with metabolic disorders"
      ]
    },
    "owners": {
      "steward": "Nobody owns the concept; clinicians answer for each patient's care.",
      "master_systems": []
    }
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q1057: metabolism",
      "url": "https://www.wikidata.org/wiki/Q1057",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Metabolism",
      "url": "https://en.wikipedia.org/wiki/Metabolism",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "pathways",
        "name": "Pathways",
        "description": "What reactions.",
        "rationale": "Pathways organise metabolism.",
        "layers": [
          {
            "id": "pathway",
            "name": "Pathway",
            "description": "Named pathway.",
            "findings": [
              {
                "id": "pathway-finding",
                "name": "Pathway",
                "description": "Pathway.",
                "questions": [
                  {
                    "text": "Which metabolic pathway is involved?",
                    "kind": "definition"
                  },
                  {
                    "text": "What does it produce?",
                    "kind": "definition"
                  }
                ]
              }
            ]
          },
          {
            "id": "regulation",
            "name": "Regulation",
            "description": "Control.",
            "findings": [
              {
                "id": "regulation-finding",
                "name": "Regulation",
                "description": "Regulation.",
                "questions": [
                  {
                    "text": "How is the pathway regulated?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which hormones affect it?",
                    "kind": "definition"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "measurement",
        "name": "Measurement",
        "description": "Metabolic rate and tests.",
        "rationale": "Measurements quantify metabolism.",
        "layers": [
          {
            "id": "rate",
            "name": "Rate",
            "description": "Energy use.",
            "findings": [
              {
                "id": "rate-finding",
                "name": "Rate",
                "description": "Metabolic rate.",
                "questions": [
                  {
                    "text": "How is metabolic rate measured?",
                    "kind": "definition"
                  },
                  {
                    "text": "What affects it?",
                    "kind": "definition"
                  }
                ]
              }
            ]
          },
          {
            "id": "tests",
            "name": "Tests",
            "description": "Blood tests.",
            "findings": [
              {
                "id": "tests-finding",
                "name": "Tests",
                "description": "Clinical tests.",
                "questions": [
                  {
                    "text": "Which tests assess metabolism clinically?",
                    "kind": "definition"
                  },
                  {
                    "text": "Who should interpret them?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "health",
        "name": "Health",
        "description": "Disorders.",
        "rationale": "Metabolic health needs professional care.",
        "layers": [
          {
            "id": "disorders",
            "name": "Disorders",
            "description": "Metabolic disease.",
            "findings": [
              {
                "id": "disorders-finding",
                "name": "Disorders",
                "description": "Metabolic disorders.",
                "questions": [
                  {
                    "text": "Which disorders affect metabolism?",
                    "kind": "definition"
                  },
                  {
                    "text": "When should someone see a doctor?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "claims",
            "name": "Claims",
            "description": "Diet marketing.",
            "findings": [
              {
                "id": "claims-finding",
                "name": "Claims",
                "description": "Evaluating claims.",
                "questions": [
                  {
                    "text": "Is a claim to boost metabolism supported by evidence?",
                    "kind": "boundary"
                  },
                  {
                    "text": "Which authority assessed it?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "applications",
        "name": "Applications",
        "description": "Biotech and drugs.",
        "rationale": "Metabolism is engineered and studied.",
        "layers": [
          {
            "id": "drugs",
            "name": "Drug metabolism",
            "description": "Interactions.",
            "findings": [
              {
                "id": "drugs-finding",
                "name": "Drug metabolism",
                "description": "How drugs are processed.",
                "questions": [
                  {
                    "text": "How is a medicine metabolised?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which interactions matter?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "biotech",
            "name": "Biotechnology",
            "description": "Engineering.",
            "findings": [
              {
                "id": "biotech-finding",
                "name": "Biotech",
                "description": "Metabolic engineering.",
                "questions": [
                  {
                    "text": "How is metabolism engineered in industry?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which rules apply?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should pathways be separate entries?",
    "How should diet claims be checked?",
    "How should metabolic disorders be linked?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}