{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-14T01:45:58Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 4, "engine": "claude", "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T11:00:00Z", "ingestedAt": "2026-10-06T07:41:40+00:00", "fields": [ "agent_conduct", "ethics", "owners" ] }, "revisions": [ { "at": "2026-10-06T22:29:19+00:00", "engine": "codex", "fields": [ "definition", "purpose", "visual_identification" ], "answering_review": "a18bfa218e9354d1bcae3fffaf06eda27af36b53c595cf2a598d11adeb408569" } ], "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T10:10:25+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q1076087", "registryId": "vr.tr.chondrosarcoma", "name": "chondrosarcoma", "version": "0.2.0-wave.4", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q1076087/", "model": { "registry_id": "vr.tr.chondrosarcoma", "name": "chondrosarcoma", "purpose": "Let an agent explain chondrosarcoma in general terms, relay subtypes, features, diagnosis and treatment approaches from oncology sources, describe the named forms and flag the stage alias, route to specialist care, and distinguish chondrosarcoma from the separate soft-tissue sarcoma called extraskeletal myxoid chondrosarcoma, osteosarcoma, benign cartilage tumours such as enchondroma and osteochondroma, and Ewing sarcoma, without diagnosing or advising individual treatment.", "definition": "A malignant tumour of cartilage-producing cells, the second most common primary bone cancer after osteosarcoma, usually affecting adults and arising in the pelvis, femur, shoulder or ribs, with forms such as conventional, myxoid, mesenchymal and dedifferentiated chondrosarcoma, while metastatic chondrosarcoma is a disease stage rather than a subtype; extraskeletal myxoid chondrosarcoma is a distinct soft-tissue sarcoma of uncertain differentiation, not a subtype of cartilage-producing chondrosarcoma despite its name. Most conventional chondrosarcomas are relatively resistant to chemotherapy and radiotherapy, so surgery is the main treatment, planned by specialist sarcoma teams, and outcomes depend on grade and location. People with a persistent deep bone pain or a growing mass should see a doctor, and specialist centres are recommended.", "what_it_is_for": "Not applicable; a cancer.", "affordances": [ "explain subtypes and features", "relay diagnosis and treatment approaches", "describe named subtypes", "route to specialist care" ], "distinguishing_features": [ "Cartilage origin", "Often chemo-resistant", "Surgery-led treatment", "Grade-dependent outcome" ], "appearance": "A cartilage-forming bone mass seen on imaging, diagnosed by biopsy.", "visual_identification": [ "Chondrosarcoma is a malignant cartilage-forming bone tumour.", "Named forms include myxoid, mesenchymal, adult mesenchymal and dedifferentiated chondrosarcoma, while metastatic chondrosarcoma denotes a disease stage.", "Extraskeletal myxoid chondrosarcoma is a distinct soft-tissue sarcoma of uncertain differentiation rather than a subtype of cartilage-producing chondrosarcoma.", "Osteosarcoma forms bone, enchondroma and osteochondroma are benign, and Ewing sarcoma is a different bone cancer of younger people." ], "physical_properties": [ { "quantity": "rank among bone cancers", "typical_range": "second most common primary", "unit": "note", "note": "after osteosarcoma" }, { "quantity": "typical age", "typical_range": "adults, often over 40", "unit": "note", "note": "" }, { "quantity": "registry parents", "typical_range": "cartilage tumor, bone sarcoma", "unit": "note", "note": "" } ], "families_and_kinds": [ "conventional chondrosarcoma", "myxoid and extraskeletal myxoid", "mesenchymal chondrosarcoma", "dedifferentiated chondrosarcoma", "clear cell chondrosarcoma" ], "related_models": [ { "relation": "is a kind of", "target": "bone sarcoma", "why": "in registry terms" }, { "relation": "is contrasted with", "target": "osteosarcoma", "why": "" }, { "relation": "is contrasted with", "target": "enchondroma", "why": "" }, { "relation": "is contrasted with", "target": "Ewing sarcoma", "why": "" } ], "identifiers": [], "standards_and_regulation": [ "WHO Classification of Bone Tumours", "ESMO and NCCN sarcoma guidelines" ], "failure_modes_and_hazards": [ "Delayed specialist referral", "Misdiagnosis as benign cartilage tumour", "Stage alias treated as subtype" ], "in_scope": [], "out_of_scope": [], "characteristics": [], "agent_conduct": { "may": [ "Explain what chondrosarcoma is, its subtypes and how it differs from benign cartilage tumours.", "Point people to a bone sarcoma specialist centre and reliable patient information." ], "must_not": [ "Diagnose, stage or grade a person's tumour from symptoms, images or reports.", "Treat metastatic chondrosarcoma as a subtype rather than a stage.", "Recommend or discourage a treatment for a specific patient.", "Disclose a person's cancer diagnosis without consent." ], "requires_human": [ "Any decision on biopsy, surgery or other treatment.", "Interpreting a patient's own scan or pathology report." ] }, "ethics": { "considerations": [ "Delay in specialist referral can cost a patient a limb or their life.", "A rare cancer leaves patients dependent on honest, accurate information." ], "affected_parties": [ "Patients", "Families and carers", "Clinicians" ] }, "owners": { "steward": "The treating clinical team for each patient; cancer registries hold population records.", "master_systems": [ "National cancer registries" ] } }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q1076087: chondrosarcoma", "url": "https://www.wikidata.org/wiki/Q1076087", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Chondrosarcoma", "url": "https://en.wikipedia.org/wiki/Chondrosarcoma", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What chondrosarcoma is.", "rationale": "Science.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is chondrosarcoma, and how does it differ from osteosarcoma, benign cartilage tumours and Ewing sarcoma?", "kind": "definition" }, { "text": "Does someone have persistent deep bone pain or a growing mass, in which case a doctor and a specialist sarcoma team should guide care?", "kind": "boundary" } ] } ] }, { "id": "subtypes", "name": "Subtypes", "description": "Named subtypes.", "findings": [ { "id": "subtypes-finding", "name": "Subtypes", "description": "Subtypes.", "questions": [ { "text": "What are conventional, myxoid, extraskeletal myxoid, mesenchymal and dedifferentiated chondrosarcoma, and what does metastatic mean?", "kind": "definition" }, { "text": "Which entry fits the specific subtype?", "kind": "action" } ] } ] } ] }, { "id": "clinical", "name": "Clinical", "description": "Diagnosis.", "rationale": "Science.", "layers": [ { "id": "diagnosis", "name": "Diagnosis", "description": "Diagnosis.", "findings": [ { "id": "diagnosis-finding", "name": "Diagnosis", "description": "Diagnosis.", "questions": [ { "text": "How are imaging and biopsy used to diagnose chondrosarcoma?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "grading", "name": "Grading", "description": "Grading.", "findings": [ { "id": "grading-finding", "name": "Grading", "description": "Grading.", "questions": [ { "text": "Why does grade strongly affect prognosis?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatment approaches.", "rationale": "Attribution.", "layers": [ { "id": "surgery", "name": "Surgery", "description": "Surgery.", "findings": [ { "id": "surgery-finding", "name": "Surgery", "description": "Surgery.", "questions": [ { "text": "Why is surgery the main treatment for most chondrosarcomas?", "kind": "provenance" }, { "text": "Which entry fits limb-sparing surgery?", "kind": "action" } ] } ] }, { "id": "resistance", "name": "Resistance", "description": "Chemo-resistance.", "findings": [ { "id": "resistance-finding", "name": "Resistance", "description": "Resistance.", "questions": [ { "text": "Why are conventional chondrosarcomas often resistant to chemotherapy and radiotherapy, as guidelines note?", "kind": "provenance" }, { "text": "Is the information current?", "kind": "boundary" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Research and support.", "rationale": "Attribution.", "layers": [ { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research directions such as IDH-targeted therapy are reported, checked against current sources?", "kind": "provenance" }, { "text": "Is the presentation neutral and attributed?", "kind": "boundary" } ] } ] }, { "id": "support", "name": "Support", "description": "Patient support.", "findings": [ { "id": "support-finding", "name": "Support", "description": "Support.", "questions": [ { "text": "What do sarcoma patient organisations offer?", "kind": "provenance" }, { "text": "Which entry fits sarcoma?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "The registry alias metastatic chondrosarcoma should be treated as a stage", "Should mesenchymal and myxoid subtypes be separate entries?", "How should sarcoma guidelines be linked and kept current?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }