{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-11T10:13:09Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 1,
    "engine": "claude",
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-05T17:00:00Z",
      "ingestedAt": "2026-10-05T13:27:13+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "owners"
      ]
    },
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-07T10:10:25+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q11364",
    "registryId": "vr.tr.hormone",
    "name": "hormone",
    "version": "0.2.0-wave.1",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "PHY.LIV"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q11364/",
  "model": {
    "registry_id": "vr.tr.hormone",
    "name": "hormone",
    "purpose": "Let an agent explain hormones in general terms by source, target and function, and point to clinicians for testing and treatment, without personal medical advice.",
    "definition": "A signalling molecule produced by glands or cells and carried, often in the blood, to act on distant target cells, regulating growth, metabolism, reproduction, mood and other functions; examples include insulin, cortisol, oestrogen, testosterone and thyroid hormones.",
    "what_it_is_for": "Coordinating body functions.",
    "affordances": [
      "explain what a hormone does in general terms",
      "identify glands and targets",
      "understand hormone tests at a general level",
      "find endocrinology services"
    ],
    "distinguishing_features": [
      "Chemical messenger",
      "Acts on distant targets",
      "Regulated by feedback",
      "Some used as medicines"
    ],
    "appearance": "Invisible molecules; measured in blood, urine or saliva.",
    "visual_identification": [
      "Peptide, steroid and amine hormones",
      "Glands such as thyroid, adrenal, pituitary",
      "Plant hormones are a related category"
    ],
    "physical_properties": [
      {
        "quantity": "Molar mass",
        "unit": "grams per mole",
        "typical_range": "",
        "note": "Molar mass is established for the identified hormone and molecular form using chemical composition or mass spectrometry."
      },
      {
        "quantity": "Amount concentration",
        "unit": "moles per liter",
        "typical_range": "",
        "note": "Concentration is measured in a specified sample using a validated assay, with results dependent on the hormone, sample matrix and collection conditions."
      },
      {
        "quantity": "Solubility",
        "unit": "grams per liter",
        "typical_range": "",
        "note": "Solubility is measured in a specified solvent at stated temperature and pH because hormones differ substantially in chemical structure."
      }
    ],
    "families_and_kinds": [
      "peptide hormones such as insulin",
      "steroid hormones such as cortisol",
      "amine hormones such as thyroid hormones",
      "neurohormones",
      "plant hormones (related)"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "signalling molecule",
        "why": "category"
      },
      {
        "relation": "is produced by",
        "target": "endocrine gland",
        "why": "source"
      },
      {
        "relation": "is studied by",
        "target": "endocrinology",
        "why": "field"
      },
      {
        "relation": "is used as",
        "target": "medication",
        "why": "therapy"
      }
    ],
    "identifiers": [],
    "standards_and_regulation": [
      "Medicines regulation for hormone therapies",
      "Anti-doping rules on hormones in sport"
    ],
    "failure_modes_and_hazards": [
      "Agents giving personal hormone advice",
      "Unregulated hormone products",
      "Oversimplified happy hormone claims"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": [],
    "agent_conduct": {
      "may": [
        "Explain what hormones do in the body, citing medical sources.",
        "Help a patient track their own prescribed hormone doses at their request."
      ],
      "must_not": [
        "Recommend starting, stopping or changing hormone treatment for a person.",
        "Help obtain hormones without a prescription or for doping.",
        "Disclose a person's hormone treatment or levels without consent.",
        "Make health claims for hormone products that the evidence does not support."
      ],
      "requires_human": [
        "Any decision on hormone therapy."
      ]
    },
    "ethics": {
      "considerations": [
        "Hormone treatments are linked to sensitive matters such as fertility, menopause and gender.",
        "Misuse of hormones harms health and undermines fair sport."
      ],
      "affected_parties": [
        "Patients",
        "Athletes",
        "Children and adolescents"
      ]
    },
    "owners": {
      "steward": "Nobody: a class of biological molecules; prescribers and medicines regulators answer for therapeutic use.",
      "master_systems": []
    }
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q11364: hormone",
      "url": "https://www.wikidata.org/wiki/Q11364",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Hormone",
      "url": "https://en.wikipedia.org/wiki/Hormone",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "biology",
        "name": "Biology",
        "description": "Function.",
        "rationale": "Biology explains hormones.",
        "layers": [
          {
            "id": "source",
            "name": "Source",
            "description": "Gland.",
            "findings": [
              {
                "id": "source-finding",
                "name": "Source",
                "description": "Source and target.",
                "questions": [
                  {
                    "text": "Which gland produces this hormone and what does it act on?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which sources describe it?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "regulation",
            "name": "Regulation",
            "description": "Feedback.",
            "findings": [
              {
                "id": "regulation-finding",
                "name": "Regulation",
                "description": "Regulation.",
                "questions": [
                  {
                    "text": "How is its level regulated by feedback?",
                    "kind": "definition"
                  },
                  {
                    "text": "What affects it?",
                    "kind": "definition"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "health",
        "name": "Health",
        "description": "Clinical care.",
        "rationale": "Clinicians test and treat.",
        "layers": [
          {
            "id": "testing",
            "name": "Testing",
            "description": "Tests.",
            "findings": [
              {
                "id": "testing-finding",
                "name": "Testing",
                "description": "Hormone tests.",
                "questions": [
                  {
                    "text": "Is the user asking to interpret their own hormone results?",
                    "kind": "boundary"
                  },
                  {
                    "text": "How should they discuss them with a clinician?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "therapy",
            "name": "Therapy",
            "description": "Treatments.",
            "findings": [
              {
                "id": "therapy-finding",
                "name": "Therapy",
                "description": "Hormone therapy.",
                "questions": [
                  {
                    "text": "What hormone therapies exist, in general terms?",
                    "kind": "definition"
                  },
                  {
                    "text": "Who prescribes them?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "safety",
        "name": "Safety",
        "description": "Products.",
        "rationale": "Unregulated products carry risks.",
        "layers": [
          {
            "id": "products",
            "name": "Products",
            "description": "Supplements.",
            "findings": [
              {
                "id": "products-finding",
                "name": "Products",
                "description": "Unregulated products.",
                "questions": [
                  {
                    "text": "Is a product claiming to change hormones regulated?",
                    "kind": "boundary"
                  },
                  {
                    "text": "Which regulator can confirm?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "sport",
            "name": "Sport",
            "description": "Doping.",
            "findings": [
              {
                "id": "sport-finding",
                "name": "Sport",
                "description": "Doping rules.",
                "questions": [
                  {
                    "text": "Is this hormone prohibited in sport?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which list applies?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "clarity",
        "name": "Clarity",
        "description": "Accurate language.",
        "rationale": "Popular claims can mislead.",
        "layers": [
          {
            "id": "claims",
            "name": "Claims",
            "description": "Pop science.",
            "findings": [
              {
                "id": "claims-finding",
                "name": "Claims",
                "description": "Popular claims.",
                "questions": [
                  {
                    "text": "Is a popular claim, such as happy hormones, oversimplified?",
                    "kind": "boundary"
                  },
                  {
                    "text": "What does evidence say?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "plants",
            "name": "Plants",
            "description": "Plant hormones.",
            "findings": [
              {
                "id": "plants-finding",
                "name": "Plants",
                "description": "Plant hormones.",
                "questions": [
                  {
                    "text": "Are plant hormones such as auxins meant?",
                    "kind": "boundary"
                  },
                  {
                    "text": "Which entry fits?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should each hormone be a separate entry?",
    "How should reference ranges be handled safely?",
    "How should plant hormones be split off?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}