{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T22:09:37Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude", "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T10:00:00Z", "ingestedAt": "2026-10-06T07:02:29+00:00", "fields": [ "agent_conduct", "ethics", "owners" ] }, "gate": { "passed": true, "version": "1.0", "at": "2026-10-06T19:51:54+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q134649", "registryId": "vr.tr.diphtheria", "name": "diphtheria", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.QLT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q134649/", "model": { "registry_id": "vr.tr.diphtheria", "name": "diphtheria", "purpose": "Let an agent explain diphtheria in general terms, relay symptoms, transmission, vaccination and treatment principles from public health sources, relay outbreak and coverage data with sources, and route personal symptoms and vaccination questions to clinicians and health authorities.", "definition": "A serious bacterial infection caused by toxin-producing strains of Corynebacterium diphtheriae and related species, affecting mainly the throat and nose, where a grey membrane forms, and sometimes the skin, with toxin damaging the heart and nerves; diphtheria spreads by respiratory droplets, was a major cause of child death before vaccination, is now rare where immunisation coverage is high, and is a notifiable disease treated with antitoxin and antibiotics.", "what_it_is_for": "Not applicable; a disease.", "affordances": [ "explain the disease and its forms", "relay vaccination and prevention information", "relay outbreak and coverage data", "route personal questions to clinicians" ], "distinguishing_features": [ "Toxin-mediated", "Pseudomembrane", "Vaccine-preventable", "Notifiable" ], "appearance": "Not a visible object; signs include sore throat, fever, swollen neck and a grey membrane in the throat.", "visual_identification": [ "Toxin-mediated infection with throat membrane", "Respiratory and cutaneous forms", "Streptococcal sore throat and other membranous infections are distinguished by testing" ], "physical_properties": [ { "quantity": "case fatality", "typical_range": "about 5-10", "unit": "percent", "note": "higher in young children and untreated cases" }, { "quantity": "vaccine introduced", "typical_range": "1920s", "unit": "decade", "note": "toxoid" } ], "families_and_kinds": [ "respiratory diphtheria including laryngotracheal and pharyngeal forms", "cutaneous diphtheria", "complications such as myocarditis and neuropathy", "rare sites such as conjunctival forms", "toxigenic Corynebacterium ulcerans infection as a related zoonosis" ], "related_models": [ { "relation": "is a kind of", "target": "primary bacterial infectious disease", "why": "in registry terms" }, { "relation": "is a kind of", "target": "notifiable disease", "why": "in most countries" }, { "relation": "is caused by", "target": "Corynebacterium diphtheriae", "why": "toxigenic strains" }, { "relation": "is prevented by", "target": "diphtheria vaccine", "why": "the toxoid" } ], "identifiers": [ { "scheme": "ICD-10", "value_or_pattern": "A36", "note": "" }, { "scheme": "ICD-11", "value_or_pattern": "1C17", "note": "" } ], "standards_and_regulation": [ "WHO immunisation schedules and position papers", "National notifiable disease regulations", "International Health Regulations for outbreaks" ], "failure_modes_and_hazards": [ "Outbreaks where coverage falls", "Delayed antitoxin treatment", "Misdiagnosis in low-incidence settings", "Agents giving personal medical advice" ], "in_scope": [], "out_of_scope": [], "characteristics": [], "agent_conduct": { "may": [ "Give public health information on diphtheria and vaccination from health authorities.", "Remind people that throat infections with breathing difficulty need urgent care." ], "must_not": [ "Discourage vaccination or spread false claims about diphtheria vaccines.", "Diagnose diphtheria or advise treatment in place of a clinician.", "Disclose a person's infection status beyond public health rules." ], "requires_human": [ "Contact tracing and notifying people of exposure." ] }, "ethics": { "considerations": [ "Diphtheria returns where vaccination falls and kills children.", "Antitoxin is scarce; access is a question of global fairness." ], "affected_parties": [ "Children", "Unvaccinated communities", "Health workers" ] }, "owners": { "steward": "The affected person and their clinicians; public health authorities record notifiable cases.", "master_systems": [ "Notifiable disease surveillance systems" ] } }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q134649: diphtheria", "url": "https://www.wikidata.org/wiki/Q134649", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Diphtheria", "url": "https://en.wikipedia.org/wiki/Diphtheria", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What diphtheria is.", "rationale": "General information.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition and forms.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is diphtheria, and what forms and complications does it have?", "kind": "definition" }, { "text": "Is the user describing symptoms, which need urgent clinical assessment?", "kind": "boundary" } ] } ] }, { "id": "transmission", "name": "Transmission", "description": "Transmission.", "findings": [ { "id": "transmission-finding", "name": "Transmission", "description": "Transmission.", "questions": [ { "text": "How does diphtheria spread, and who is at risk?", "kind": "definition" }, { "text": "Which entry fits the bacterium?", "kind": "action" } ] } ] } ] }, { "id": "prevent", "name": "Prevent", "description": "Vaccination and control.", "rationale": "Public health.", "layers": [ { "id": "vaccination", "name": "Vaccination", "description": "Vaccination.", "findings": [ { "id": "vaccination-finding", "name": "Vaccination", "description": "Vaccination.", "questions": [ { "text": "What do immunisation schedules recommend, including boosters?", "kind": "provenance" }, { "text": "Is the user asking about their own vaccination, which needs a clinician or health authority?", "kind": "boundary" } ] } ] }, { "id": "outbreaks", "name": "Outbreaks", "description": "Outbreaks and surveillance.", "findings": [ { "id": "outbreaks-finding", "name": "Outbreaks", "description": "Outbreaks.", "questions": [ { "text": "Where have outbreaks occurred, and what do coverage data show, with sources?", "kind": "measurement" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "clinical", "name": "Clinical", "description": "Diagnosis and treatment.", "rationale": "Clinical.", "layers": [ { "id": "diagnosis", "name": "Diagnosis", "description": "Diagnosis.", "findings": [ { "id": "diagnosis-finding", "name": "Diagnosis", "description": "Diagnosis.", "questions": [ { "text": "How is diphtheria diagnosed and confirmed?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatment principles.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "What treatment do guidelines describe, in general terms?", "kind": "provenance" }, { "text": "Is the presentation free of personal medical advice?", "kind": "boundary" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "History.", "rationale": "Context.", "layers": [ { "id": "history", "name": "History", "description": "History.", "findings": [ { "id": "history-finding", "name": "History", "description": "History.", "questions": [ { "text": "How did diphtheria affect populations historically, and how were antitoxin and vaccine developed?", "kind": "provenance" }, { "text": "Which entry fits the history of vaccination?", "kind": "action" } ] } ] }, { "id": "teach", "name": "Teach", "description": "Teaching.", "findings": [ { "id": "teach-finding", "name": "Teach", "description": "Teaching.", "questions": [ { "text": "How is diphtheria used to teach toxin-mediated disease and vaccination?", "kind": "provenance" }, { "text": "Which entry fits vaccine-preventable diseases?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should complications be separate entries?", "How should WHO data be linked?", "The registry entry has merged aliases naming complications and rare forms; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }