{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T11:13:28Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 15.6, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a09551-7f5c-7613-ae8d-947845f7caaa\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: Mees' lines\nSense to describe: (none recorded)\nDomain code: XCT.STA\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Batch 044: 1001 reg", "usd": 0.0, "recall": true }, "codex": { "seconds": 67.4, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a09551-7f5a-7bf2-b076-3d2092b6d18a\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: Mees' lines\nRegistry id: vr.tr.mees-lines\nPlane / domain: XCT / XCT.STA\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\n\nC" } }, "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T12:00:00Z", "ingestedAt": "2026-10-06T08:43:09+00:00", "fields": [ "agent_conduct", "ethics", "failure_modes_and_hazards", "owners", "visual_identification" ] }, "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T10:10:26+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q1567863", "registryId": "vr.tr.mees-lines", "name": "Mees' lines", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q1567863/", "model": { "registry_id": "vr.tr.mees-lines", "name": "Mees' lines", "purpose": "Enable an agent to recognise, document and follow suspected Mees' lines while keeping the observed nail sign separate from any inferred underlying cause.", "definition": "Mees' lines are transverse white bands in the nail plate, a form of true leukonychia caused by disturbed nail-matrix keratinisation, that do not blanch under pressure and move distally as the nail grows.", "scope_statement": "This model owns vr.tr.mees-lines: transverse white bands within the nail plate, their identification, distribution, evolution and evidence linking them to possible causes; it treats them as a clinical sign rather than an abstract concept or a diagnosis of poisoning.", "in_scope": [ "Identification of transverse true leukonychia consistent with Mees' lines", "Band morphology and distribution across fingernails and toenails", "Pressure response, surface contour and movement with nail growth", "Temporal relationships to documented exposures, treatments and illnesses", "Diagnostic uncertainty, clinical review and serial observation" ], "out_of_scope": [ "Comprehensive anatomy and physiology of the nail apparatus", "Diagnosis and treatment of arsenic or other toxic exposures", "Management of systemic illnesses associated with nail changes", "Muehrcke's lines, Beau's lines and other nail disorders as independent conditions", "General chemotherapy prescribing and adverse-effect management" ], "distinguishing_features": [ "White transverse bands embedded in the plate support Mees' lines; punctate spots, longitudinal streaks and diffuse whitening require other classifications. [DermNet: White nail](https://dermnetnz.org/topics/white-nail)", "Persistence of whiteness under pressure supports true leukonychia over the apparent leukonychia of Muehrcke's lines. [Leukonychia review](https://pmc.ncbi.nlm.nih.gov/articles/PMC8809498/)", "Distal migration with nail growth supports a plate-based band; apparent leukonychia remains positioned over the nail bed. [Leukonychia review](https://pmc.ncbi.nlm.nih.gov/articles/PMC8809498/)", "Inspect and palpate for a transverse depression to distinguish a white band from a possible Beau's line, recording both features if they coexist.", "Superficial powdery or removable whiteness suggests pseudoleukonychia rather than an intrinsic white band. [Leukonychia review](https://pmc.ncbi.nlm.nih.gov/articles/PMC8809498/)" ], "characteristics": [ { "name": "Affected nails", "kind": "category", "unit_or_values": "Hand or foot, side and digit; inspected and uninspected nails distinguished", "why_it_matters": "Allows assessment of localised versus widespread involvement without treating unexamined nails as normal." }, { "name": "Band geometry", "kind": "measurement", "unit_or_values": "Count per nail; width in mm; transverse coverage as percentage of plate width", "why_it_matters": "Makes the visible pattern comparable between examinations." }, { "name": "Band position", "kind": "measurement", "unit_or_values": "Distance in mm from proximal nail fold to a specified band edge, with observation date", "why_it_matters": "Provides a repeatable reference for tracking distal movement." }, { "name": "Pressure response", "kind": "category", "unit_or_values": "Persists; fades; indeterminate; not tested", "why_it_matters": "Contributes to distinguishing plate-based from nail-bed whitening." }, { "name": "Surface contour", "kind": "category", "unit_or_values": "Smooth; depressed; ridged; scaling; mixed; not assessed", "why_it_matters": "Separates colour change from structural changes and permits coexisting findings." }, { "name": "Serial movement", "kind": "measurement", "unit_or_values": "Band displacement in mm over recorded days; indeterminate when observations are insufficient", "why_it_matters": "Tests whether the same band moves with the growing plate." }, { "name": "Candidate trigger", "kind": "relation", "unit_or_values": "Linked exposure, medication course, illness or local injury with dates and evidence", "why_it_matters": "Supports investigation without encoding an association as an established cause." }, { "name": "Identification state", "kind": "state", "unit_or_values": "Suspected; clinically supported; indeterminate; reclassified", "why_it_matters": "Keeps photographic suspicion distinct from an adequately examined finding." } ], "affordances": [ "Create a nail-by-nail observation record with calibrated photographs", "Compare pressure response, contour and growth behaviour against competing explanations", "Track individual bands through serial examinations", "Construct a qualified timeline relating band development to documented events", "Prepare a clinical review summary showing supporting evidence and unresolved alternatives", "Revise the identification or causal interpretation when new examination findings arrive" ], "agent_conduct": { "may": [ "Explain what Mees' lines are and the conditions linked to them from reputable medical sources.", "Advise a person who notices new white bands across several nails to see a doctor." ], "must_not": [ "Diagnose poisoning or illness from photos of nails.", "Accuse a named person of poisoning someone on the basis of nail changes.", "Disclose a person's medical or toxicology findings without consent.", "Confuse the bands with harmless white spots and tell a person not to worry." ], "requires_human": [ "Reporting suspected poisoning to authorities.", "Ordering or interpreting toxicology tests." ] }, "ethics": { "considerations": [ "Nail signs can point to poisoning, a crime that needs careful investigation, not rumour.", "Wrong suspicion can destroy relationships and reputations." ], "affected_parties": [ "Patients", "People suspected without evidence", "Families" ] }, "owners": { "steward": "Nobody owns the sign; patients and their clinicians answer for care.", "master_systems": [] }, "visual_identification": [ "Single white bands running across the full width of the nail.", "Do not fade when the nail is pressed and move toward the tip as the nail grows.", "Often appear on several nails at the same level." ], "failure_modes_and_hazards": [ "May be a late sign of heavy metal poisoning, chemotherapy or severe illness.", "Easily overlooked or mistaken for minor nail damage." ], "what_it_is_for": [ "Mees' lines are encountered during nail examination as transverse white bands within the nail plate.", "They are documented alongside nail growth, medical history and other findings because their appearance alone does not establish an underlying cause." ], "standards_and_regulation": [ "The International Classification of Diseases, Tenth Revision, issued by the World Health Organization, includes leukonychia under L60.8 for other nail disorders, providing a classification applicable to Mees' lines." ] }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q1567863: Mees' lines", "url": "https://www.wikidata.org/wiki/Q1567863", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Mees' lines", "url": "https://en.wikipedia.org/wiki/Mees%27_lines", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "recognition-and-name-boundary", "name": "Recognition and name boundary", "description": "Establish what appearance is being labelled Mees' lines and which naming convention is being used.", "rationale": "The eponym must not silently convert a white nail band into a specific etiological diagnosis.", "layers": [ { "id": "transverse-band-identification", "name": "Transverse band identification", "description": "Describe the visible pattern before interpreting its origin.", "findings": [ { "id": "candidate-white-bands", "name": "Candidate white bands", "description": "Record colour, transverse orientation, continuity and relationship to the lunula for each candidate band.", "questions": [ { "text": "Are the white areas transverse bands rather than spots, longitudinal streaks or diffuse whitening?", "kind": "definition", "id": "candidate-white-bands-q01" }, { "text": "What are each band's width, continuity and transverse coverage on the affected nail?", "kind": "measurement", "id": "candidate-white-bands-q02" } ] } ] }, { "id": "eponym-usage", "name": "Eponym usage", "description": "Expose differences in the scope of the name rather than forcing all transverse leukonychia into one usage.", "findings": [ { "id": "declared-naming-convention", "name": "Declared naming convention", "description": "Retain the source's usage: DermNet equates striate leukonychia with Mees' lines, while a specialist review distinguishes trauma-induced transverse true leukonychia in its terminology. [DermNet](https://dermnetnz.org/topics/white-nail), [Leukonychia review](https://pmc.ncbi.nlm.nih.gov/articles/PMC8809498/)", "questions": [ { "text": "Which clinical reference or examiner supplied the Mees' lines label?", "kind": "provenance", "id": "declared-naming-convention-q01" }, { "text": "Does that source include locally traumatic transverse leukonychia within the eponym?", "kind": "boundary", "id": "declared-naming-convention-q02" } ] } ] } ] }, { "id": "plate-localisation-and-mimics", "name": "Plate localisation and mimics", "description": "Test whether the whitening belongs to the nail plate and document competing nail findings.", "rationale": "A transverse white appearance alone cannot settle the distinction from nail-bed or surface abnormalities.", "layers": [ { "id": "pressure-and-growth-tests", "name": "Pressure and growth tests", "description": "Combine examination and follow-up evidence about anatomical localisation.", "findings": [ { "id": "plate-localisation-evidence", "name": "Plate localisation evidence", "description": "Record pressure response and serial displacement separately, including unperformed or inconclusive tests.", "questions": [ { "text": "Does the band remain visible when pressure is applied during examination?", "kind": "measurement", "id": "plate-localisation-evidence-q01" }, { "text": "Does a recognisably identical band move distally between dated observations?", "kind": "measurement", "id": "plate-localisation-evidence-q02" } ] } ] }, { "id": "contour-and-surface-assessment", "name": "Contour and surface assessment", "description": "Assess structural grooves, superficial whitening and mixed appearances.", "findings": [ { "id": "alternative-or-coexisting-signs", "name": "Alternative or coexisting signs", "description": "Document whether a groove, surface alteration or other whitening pattern better explains the observation or occurs alongside it.", "questions": [ { "text": "Is the transverse feature a colour band, a palpable depression, or both?", "kind": "boundary", "id": "alternative-or-coexisting-signs-q01" }, { "text": "What examination evidence distinguishes intrinsic whitening from superficial scale, a coating or another nail disorder?", "kind": "boundary", "id": "alternative-or-coexisting-signs-q02" } ] } ] } ] }, { "id": "distribution-and-band-history", "name": "Distribution and band history", "description": "Capture which nails are involved and how individual bands change over time.", "rationale": "Distribution and migration provide different evidence from a single close-up photograph.", "layers": [ { "id": "nail-by-nail-pattern", "name": "Nail-by-nail pattern", "description": "Compare band burden and placement across explicitly examined digits.", "findings": [ { "id": "mapped-involvement", "name": "Mapped involvement", "description": "Maintain a digit map with band counts, positions and examination completeness.", "questions": [ { "text": "Which fingernails and toenails were examined, and which contain candidate bands?", "kind": "measurement", "id": "mapped-involvement-q01" }, { "text": "Are band number and placement similar across nails, or is involvement restricted to particular digits?", "kind": "measurement", "id": "mapped-involvement-q02" } ] } ] }, { "id": "serial-band-tracking", "name": "Serial band tracking", "description": "Track matched bands without treating their position as an exact exposure date.", "findings": [ { "id": "qualified-growth-timeline", "name": "Qualified growth timeline", "description": "Separate directly observed displacement from any inferred formation interval and document the growth assumptions used.", "questions": [ { "text": "What dated measurements establish displacement of the same band using the same anatomical landmark?", "kind": "measurement", "id": "qualified-growth-timeline-q01" }, { "text": "If formation timing is estimated, what nail-specific growth evidence and uncertainty support the interval?", "kind": "provenance", "id": "qualified-growth-timeline-q02" } ] } ] } ] }, { "id": "causal-interpretation-and-review", "name": "Causal interpretation and review", "description": "Connect the nail sign to relevant history while preserving uncertainty and actionable review needs.", "rationale": "Mees' lines can prompt investigation, but the model must not equate their presence with confirmed poisoning.", "layers": [ { "id": "trigger-evidence", "name": "Trigger evidence", "description": "Assess documented candidate events against the observed nail pattern and timing.", "findings": [ { "id": "supported-trigger-hypotheses", "name": "Supported trigger hypotheses", "description": "Record candidate exposures and treatments separately from causal conclusions; reported associations include heavy metals and chemotherapy. [DermNet: White nail](https://dermnetnz.org/topics/white-nail)", "questions": [ { "text": "Which exposure, treatment, illness or local injury is documented, and by what record?", "kind": "provenance", "id": "supported-trigger-hypotheses-q01" }, { "text": "What evidence supports or contradicts its temporal and anatomical fit with the bands?", "kind": "boundary", "id": "supported-trigger-hypotheses-q02" }, { "text": "What independent clinical evidence would be needed before attributing the bands to that candidate?", "kind": "action", "id": "supported-trigger-hypotheses-q03" } ] } ] }, { "id": "review-and-reassessment", "name": "Review and reassessment", "description": "Turn incomplete identification into a defined clinical review or observation task.", "findings": [ { "id": "evidence-linked-next-step", "name": "Evidence-linked next step", "description": "Specify the missing examination, history or follow-up observation and record how its result changes the interpretation.", "questions": [ { "text": "What clinical review is warranted by the person's exposure history and accompanying symptoms?", "kind": "action", "id": "evidence-linked-next-step-q01" }, { "text": "What follow-up observation would strengthen the identification or require reclassification?", "kind": "action", "id": "evidence-linked-next-step-q02" }, { "text": "Have existing bands grown out, new bands appeared, or observation ended before their course could be established?", "kind": "measurement", "id": "evidence-linked-next-step-q03" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Terminology overlaps with transverse or striate leukonychia; a researcher should check how narrowly each source uses the eponym.", "The appearance is a clinical sign rather than an independently established cause or diagnosis.", "This description is based on recall; no sources or identifier codes were verified." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of Mees' lines this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "A clinical sign that can prompt investigation of previous toxic exposure, severe systemic illness, or chemotherapy.", "Classically associated with arsenic poisoning, although they are not specific to it.", "Their distance from the proximal nail fold can help estimate the timing of a previous insult when nail growth rate is considered." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of Mees' lines this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Treating Mees' lines alone as proof of arsenic poisoning.", "Confusing white nail-plate bands with nail-bed changes or transverse grooves.", "Dating an exposure too precisely despite variation in nail growth rate.", "Assuming that absence of the lines excludes toxic exposure." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of Mees' lines this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "Muehrcke's lines", "difference": "Usually paired white bands arising from the nail bed; they blanch with pressure and do not migrate with nail growth." }, { "name": "Beau's lines", "difference": "Transverse depressions caused by interrupted nail growth; Mees' lines are white bands without a corresponding groove." }, { "name": "Leukonychia", "difference": "The broader category of white nail discoloration; Mees' lines are a transverse form of true leukonychia." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of Mees' lines this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Should this registry entry adopt broad usage encompassing transverse true leukonychia or reserve the eponym for a narrower etiological context?", "What reproducible examination protocol and evidence threshold should distinguish suspected from clinically supported Mees' lines?", "How accurately can formation timing be estimated across different nails, growth disturbances and delays before a band becomes visible?", "Which reported etiological associations have evidence beyond isolated case reports, and how much diagnostic weight should each receive?", "Does an existing Vercy world model already own this clinical sign, requiring this registry entry to link to it instead of creating a duplicate?" ], "statistics": { "bundles": 5, "layers": 9, "findings": 12, "questions": 22 } }