{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T10:43:32Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 21.5, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a09536-18d6-7961-8abe-6be835368831\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: karrikin\nSense to describe: (none recorded)\nDomain code: PHY.MAT\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Batch 043: 1001 regist", "usd": 0.0, "recall": true }, "codex": { "seconds": 67.7, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a09536-18d6-7992-9a49-4cc0f5abacc6\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: karrikin\nRegistry id: vr.tr.karrikin\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\n\nContex" } }, "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T12:00:00Z", "ingestedAt": "2026-10-06T08:52:56+00:00", "fields": [ "agent_conduct", "ethics", "failure_modes_and_hazards", "owners", "visual_identification" ] }, "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T10:10:26+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q1573150", "registryId": "vr.tr.karrikin", "name": "karrikin", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q1573150/", "model": { "registry_id": "vr.tr.karrikin", "name": "karrikin", "purpose": "Enable an agent to identify karrikin material, assess its chemical and biological state, and judge whether evidence supports a proposed plant treatment or research use.", "definition": "A karrikin is a member of a family of plant-active compounds with a fused butenolide-pyran ring system, formed during the combustion of plant material, that can stimulate seed germination and influence seedling development.", "scope_statement": "This model owns vr.tr.karrikin in PHY / PHY.MAT as a provisional chemical-family entry, recording the specific congener or mixture represented by each material and linking its composition, condition and demonstrated activity without assuming that the unqualified name means KAR1.", "in_scope": [ "Karrikin family membership and identification of individual congeners", "Congener composition, purity and analytical confirmation of material", "Physical state, solution concentration and stability under recorded conditions", "Plant responses attributable to a specified karrikin exposure", "Evidence supporting handling, experimental use and jurisdiction-specific status" ], "out_of_scope": [ "Whole smoke, smoke-water and biochar composition beyond their karrikin content", "Combustion, extraction and synthesis processes as independently modelled activities", "Strigolactones and other chemically distinct germination signals", "KAI2 proteins and plant signalling networks as independent biological entities", "Seed lots, plant organisms and fire ecology beyond their relationship to a karrikin observation" ], "distinguishing_features": [ "Require structural evidence for the fused butenolide-pyran framework; smoke origin or germination activity alone does not establish karrikin identity.", "Distinguish KAR1, also called karrikinolide, from KAR2 and other congeners by their molecular structures and substitution patterns; do not treat congener labels as interchangeable.", "Distinguish an identified karrikin from smoke-water or biochar containing it: a matrix-level response does not identify the active constituent.", "Distinguish karrikins from strigolactones through full molecular identity; a shared butenolide feature or overlapping signalling requirement is insufficient.", "Treat KAI2-pathway activation as biological evidence rather than a chemical identity test or proof that the material is an endogenous plant hormone." ], "characteristics": [ { "name": "Identity resolution", "kind": "state", "unit_or_values": "family only | identified congener | characterised mixture | unresolved material", "why_it_matters": "Determines whether molecular constants, identifiers and activity evidence can be assigned to the material." }, { "name": "Congener identity", "kind": "category", "unit_or_values": "KAR designation accompanied by a verified structure and chemical name", "why_it_matters": "Congeners can differ in biological activity and must remain distinguishable." }, { "name": "Chemical identifier mapping", "kind": "relation", "unit_or_values": "Verified structure-linked CAS number, PubChem CID and EC number where available", "why_it_matters": "Prevents identifiers for one congener from being applied to the whole family." }, { "name": "Congener content and purity", "kind": "measurement", "unit_or_values": "Mass fraction, molar fraction or analytical area percentage, with method and uncertainty", "why_it_matters": "Supports dose calculation and separates karrikin effects from impurities or other constituents." }, { "name": "Physical state and thermal properties", "kind": "measurement", "unit_or_values": "Observed phase; melting, boiling or decomposition temperature in °C with pressure, method and congener", "why_it_matters": "Supports material recognition without inventing family-wide physical constants." }, { "name": "Delivered karrikin concentration", "kind": "measurement", "unit_or_values": "mol/L or mass per treatment volume, with solvent, matrix and exposure duration", "why_it_matters": "Makes treatment evidence interpretable and reproducible." }, { "name": "Storage and solution integrity", "kind": "state", "unit_or_values": "Verified intact | changed | untested, with temperature, light, solvent, pH and elapsed time", "why_it_matters": "Connects nominal identity and dose to the material actually applied." }, { "name": "Plant assay context", "kind": "relation", "unit_or_values": "Species, genotype, seed lot, dormancy status, developmental stage and environmental conditions", "why_it_matters": "Bounds claims about responsiveness and prevents unsupported transfer between plants." }, { "name": "Observed biological response", "kind": "measurement", "unit_or_values": "Germination percentage, time to germination or defined seedling endpoint, relative to controls", "why_it_matters": "Separates measured activity from general claims that karrikins promote growth." }, { "name": "Handling and regulatory evidence", "kind": "relation", "unit_or_values": "Material-specific SDS, applicable classification, exposure-limit evidence and use status, with jurisdiction and date", "why_it_matters": "Distinguishes documented requirements from missing information." } ], "affordances": [ "Resolve a material labelled karrikin to a verified congener or explicitly unresolved family member.", "Compare material lots using analytical identity, congener content and impurities.", "Calculate congener-specific treatment concentrations from verified stock content.", "Select and interpret controlled germination or seedling assays within a stated plant context.", "Flag storage changes, matrix confounding or missing handling evidence before experimental use." ], "agent_conduct": { "may": [ "Explain karrikins as smoke-derived compounds that affect seed germination, citing plant biology research.", "Describe their role in fire-adapted ecosystems and restoration research." ], "must_not": [ "Present karrikin research as proven for crop yields or restoration where evidence is preliminary.", "Encourage burning vegetation to produce karrikins outside lawful, controlled fire management.", "Overstate what is known about karrikin effects on human health." ], "requires_human": [ "Applying karrikin treatments in field restoration or agriculture at scale." ] }, "ethics": { "considerations": [ "Overstated research claims can mislead restoration and farming decisions.", "Fire use carries risks to people, property and ecosystems." ], "affected_parties": [ "Researchers", "Land managers", "Fire-adapted ecosystems" ] }, "owners": { "steward": "Nobody owns the class of compounds; researchers and suppliers answer for samples they hold.", "master_systems": [] }, "visual_identification": [ "Identified by container label, chemical name and identifier, and certificate of analysis rather than by appearance alone." ], "failure_modes_and_hazards": [ "Misapplied research leading to failed restoration.", "Wildfire risk if fire is used carelessly." ], "what_it_is_for": [ "Karrikins are encountered in plant smoke chemistry and research on seed germination and seedling development.", "They are studied in fire ecology, restoration research and controlled experiments on plant signaling.", "Their effects are evaluated for particular species and experimental conditions because responses vary among plants." ], "standards_and_regulation": [ "The Globally Harmonized System of Classification and Labelling of Chemicals, issued by the United Nations, provides the framework for assessing and communicating hazards of karrikin substances and mixtures where implemented." ] }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q1573150: karrikin", "url": "https://www.wikidata.org/wiki/Q1573150", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Karrikin", "url": "https://en.wikipedia.org/wiki/Karrikin", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "chemical-identity", "name": "Chemical identity and registry boundary", "description": "Establish what the unqualified registry name and each represented material denote.", "rationale": "A family name cannot safely inherit the identifiers or properties of its best-known congener.", "layers": [ { "id": "family-and-congener", "name": "Family and congener", "description": "Separate the shared chemical family from individual molecular identities.", "findings": [ { "id": "congener-specific-recognition", "name": "Congener-specific recognition", "description": "Record the molecular structure underlying each KAR label. Experimental work distinguishes KAR1 and KAR2 and investigates differing ligand responses: [Lotus japonicus karrikin receptor study](https://pmc.ncbi.nlm.nih.gov/articles/PMC7808659/).", "questions": [ { "text": "Does the registry's source use karrikin for the family or for a particular congener?", "kind": "boundary", "id": "congener-specific-recognition-q01" }, { "text": "Which verified structure, substitution pattern and synonyms establish the material's congener identity?", "kind": "definition", "id": "congener-specific-recognition-q02" } ] } ] }, { "id": "identifier-and-origin", "name": "Identifier and origin evidence", "description": "Connect chemical identity to external records and material provenance.", "findings": [ { "id": "identity-traceability", "name": "Identity traceability", "description": "Keep congener identifiers distinct from supplier product codes and from the smoke-derived or synthetic origin of a sample.", "questions": [ { "text": "Which authoritative records map CAS, PubChem or EC identifiers to the exact structure?", "kind": "provenance", "id": "identity-traceability-q01" }, { "text": "Was this material synthesised, isolated from smoke or supplied in a mixture, and what record supports that history?", "kind": "provenance", "id": "identity-traceability-q02" } ] } ] } ] }, { "id": "material-integrity", "name": "Congener content and material integrity", "description": "Describe the chemical material that is actually stored, measured and delivered.", "rationale": "Trace activity and mixed smoke matrices make nominal labels inadequate for interpreting a karrikin experiment.", "layers": [ { "id": "composition-and-confirmation", "name": "Composition and confirmation", "description": "Record evidence that identifies and quantifies the intended karrikin.", "findings": [ { "id": "analytical-attribution", "name": "Analytical attribution", "description": "Associate identity and content claims with suitable structural or chromatographic evidence, reference materials and stated limits.", "questions": [ { "text": "Which analytical results distinguish the target congener from other karrikins and co-occurring compounds?", "kind": "measurement", "id": "analytical-attribution-q01" }, { "text": "What amount of the target congener is present, and does the reported purity measure mass fraction or only analytical signal?", "kind": "measurement", "id": "analytical-attribution-q02" } ] } ] }, { "id": "condition-and-stability", "name": "Condition and stability", "description": "Track phase, stock preparation and changes before application.", "findings": [ { "id": "available-intact-material", "name": "Available intact material", "description": "Treat solubility, thermal properties and stability as congener- and condition-specific evidence rather than assumed family constants.", "questions": [ { "text": "What phase, solubility and thermal-property measurements exist for this congener under stated conditions?", "kind": "measurement", "id": "available-intact-material-q01" }, { "text": "What evidence shows that the stock remains dissolved and chemically intact after its recorded storage and handling?", "kind": "measurement", "id": "available-intact-material-q02" } ] } ] } ] }, { "id": "biological-response", "name": "Plant response and signalling evidence", "description": "Connect a defined karrikin treatment to measured plant responses and bounded mechanistic interpretations.", "rationale": "Karrikin activity depends on biological context, and response alone cannot establish chemical identity or a universal mechanism.", "layers": [ { "id": "germination-and-establishment", "name": "Germination and seedling response", "description": "Record the exposure and plant conditions behind each activity claim.", "findings": [ { "id": "contextual-dose-response", "name": "Contextual dose response", "description": "Represent stimulation, inhibition or absence of effect through measured endpoints, controls and uncertainty.", "questions": [ { "text": "For which species, genotype, seed lot and dormancy condition was this congener tested?", "kind": "provenance", "id": "contextual-dose-response-q01" }, { "text": "How did germination or a defined seedling endpoint change across concentrations and exposure durations relative to vehicle controls?", "kind": "measurement", "id": "contextual-dose-response-q02" }, { "text": "Were light, temperature and baseline seed viability controlled sufficiently to interpret the response?", "kind": "boundary", "id": "contextual-dose-response-q03" } ] } ] }, { "id": "signalling-attribution", "name": "Signalling attribution", "description": "Distinguish pathway dependence from direct molecular recognition.", "findings": [ { "id": "bounded-mechanistic-evidence", "name": "Bounded mechanistic evidence", "description": "Record evidence type and organism for signalling claims. Arabidopsis experiments support KAI2- and MAX2-mediated seedling responses under tested conditions: [primary experimental study](https://pubmed.ncbi.nlm.nih.gov/23142794/).", "questions": [ { "text": "Does the evidence demonstrate direct ligand binding, genetic pathway dependence or only a correlated response?", "kind": "boundary", "id": "bounded-mechanistic-evidence-q01" }, { "text": "Which congener, receptor variant and organism were tested, and what supports extending that result to this material's proposed use?", "kind": "provenance", "id": "bounded-mechanistic-evidence-q02" } ] } ] } ] }, { "id": "experimental-use", "name": "Treatment design and use constraints", "description": "Turn material and response evidence into reviewable experimental decisions.", "rationale": "A karrikin treatment needs interpretable delivery and material-specific handling evidence, particularly when extrapolating from laboratory assays.", "layers": [ { "id": "delivery-and-controls", "name": "Delivery and controls", "description": "Specify how the identified congener reaches seeds or seedlings.", "findings": [ { "id": "interpretable-treatment", "name": "Interpretable treatment", "description": "Link stock content, dilution, carrier and exposure to controls that isolate the proposed karrikin effect.", "questions": [ { "text": "What stock assay, dilution and application volume establish the delivered concentration of each congener?", "kind": "measurement", "id": "interpretable-treatment-q01" }, { "text": "Which vehicle, untreated and matrix controls are needed to separate karrikin activity from carrier or smoke-water effects?", "kind": "action", "id": "interpretable-treatment-q02" }, { "text": "What result would justify continuing, revising or stopping this treatment in the target plant context?", "kind": "action", "id": "interpretable-treatment-q03" } ] } ] }, { "id": "handling-and-use-status", "name": "Handling and use status", "description": "Establish evidence relevant to the actual material and intended application.", "findings": [ { "id": "documented-use-boundaries", "name": "Documented use boundaries", "description": "Record documented classifications and restrictions separately from unassessed hazards or absent records; biological potency does not establish a hazard classification.", "questions": [ { "text": "Which current SDS and classification records apply to this congener, concentration and formulation, and are exposure limits documented or unavailable?", "kind": "provenance", "id": "documented-use-boundaries-q01" }, { "text": "What jurisdiction-specific evidence supports the intended laboratory, agricultural or restoration use?", "kind": "action", "id": "documented-use-boundaries-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "The registry term is interpreted as the compound family; confirm whether the intended entry instead refers specifically to KAR1.", "Exact substance identifiers, physical constants, purity specifications and hazard classifications should be checked for each individual karrikin.", "KAI2 participates in karrikin responses, but this should not be taken as establishing smoke-derived karrikins as its natural endogenous ligands." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of karrikin this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Karrikin 1 (KAR1)", "Karrikin 2 (KAR2)" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of karrikin this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "Research compound designation", "value_or_pattern": "KAR1, KAR2 and other numbered KAR designations", "note": "These distinguish individual compounds; karrikin denotes the family rather than one chemically unique substance." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of karrikin this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Research on smoke-stimulated seed germination and post-fire plant establishment.", "Experimental germination treatments for responsive species.", "Research on KAI2-dependent signalling and seedling development." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of karrikin this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Molar mass of KAR1", "typical_range": "150.13", "unit": "g/mol" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of karrikin this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Germination responses depend on species, seed dormancy state and treatment conditions; karrikins are not universal germination stimulants.", "Smoke-derived mixtures contain other biologically active constituents, so their effects cannot be attributed to karrikins alone.", "Biological activity does not establish safety for handlers or the environment; compound-specific toxicological information requires verification." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of karrikin this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "Strigolactones", "difference": "Strigolactones are a distinct family of plant-produced signals with roles in branching and rhizosphere interactions; a shared butenolide feature does not make them karrikins." }, { "name": "Smoke water", "difference": "Smoke water is a mixture that can contain karrikins alongside other combustion products, rather than a defined karrikin compound." }, { "name": "Butenolide", "difference": "Butenolide describes a broader chemical scaffold; karrikins have a particular fused ring system." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of karrikin this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Does the originating registry record denote the karrikin family or specifically KAR1, and does an existing Vercy model already own that concept?", "Which congeners and structure-linked identifiers should this registry entry recognise without creating unauthorised separate entries?", "Which reliable measurements establish congener-specific physical constants, aqueous solubility and storage stability?", "Which plant contexts have reproducible concentration-response evidence, and how far can laboratory results support field application?", "What material-specific hazard, exposure and jurisdictional use records exist, and which aspects remain unassessed?" ], "statistics": { "bundles": 5, "layers": 9, "findings": 15, "questions": 25 } }