{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-11T15:26:27Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 1,
    "engine": "claude",
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-05T18:00:00Z",
      "ingestedAt": "2026-10-05T13:27:17+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "owners"
      ]
    },
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-06T19:51:58+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q2661443",
    "registryId": "vr.tr.endocrine-system-disease",
    "name": "endocrine system disease",
    "version": "0.2.0-wave.1",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "XCT.STA"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q2661443/",
  "model": {
    "registry_id": "vr.tr.endocrine-system-disease",
    "name": "endocrine system disease",
    "purpose": "Let an agent give general information on endocrine diseases, route emergencies such as adrenal or thyroid crises to urgent care, and help people find specialists without individual medical advice.",
    "definition": "A disease of the endocrine glands or hormone system, including thyroid, adrenal, pituitary, parathyroid, pancreatic and gonadal disorders, diabetes, and endocrine neoplasms such as thyroid or adrenal tumours, arising from hormone excess, deficiency or gland tumours and managed by endocrinology.",
    "what_it_is_for": "A category of health conditions affecting hormones.",
    "affordances": [
      "explain endocrine diseases in general terms",
      "recognise emergencies",
      "find endocrinologists and patient organisations",
      "prepare questions for consultations"
    ],
    "distinguishing_features": [
      "Hormone excess or deficiency",
      "Gland disorders and tumours",
      "Diagnosed by hormone testing",
      "Often lifelong management"
    ],
    "appearance": "Not physical; diagnosed through symptoms, hormone tests and imaging.",
    "visual_identification": [
      "Hormone imbalance",
      "Blood tests and imaging",
      "Metabolic diseases may overlap"
    ],
    "physical_properties": [],
    "families_and_kinds": [
      "thyroid diseases",
      "diabetes and pancreatic endocrine disorders",
      "adrenal and pituitary diseases",
      "parathyroid and bone metabolism disorders",
      "endocrine neoplasms"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "disease of anatomical entity",
        "why": "category"
      },
      {
        "relation": "affects",
        "target": "endocrine system",
        "why": "system"
      },
      {
        "relation": "is treated by",
        "target": "endocrinology",
        "why": "specialty"
      },
      {
        "relation": "is related to",
        "target": "inflammatory bowel diseases",
        "why": "other chronic disease group"
      }
    ],
    "identifiers": [],
    "standards_and_regulation": [
      "Endocrine society clinical guidelines",
      "Medicines regulation"
    ],
    "failure_modes_and_hazards": [
      "Missed emergencies",
      "Agents giving individual medical advice",
      "Unregulated hormone products"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": [],
    "agent_conduct": {
      "may": [
        "Explain endocrine diseases in general terms from clinical sources.",
        "Remind a patient of treatments and checks their clinician has set."
      ],
      "must_not": [
        "Diagnose an endocrine condition or adjust hormone or insulin doses.",
        "Promote hormones or supplements for uses that are not approved.",
        "Share a person's diagnosis without their consent.",
        "Blame people for conditions such as diabetes."
      ],
      "requires_human": [
        "Any change in hormone, insulin or other medication.",
        "Acting on a reading that suggests a dangerous blood sugar or hormone crisis."
      ]
    },
    "ethics": {
      "considerations": [
        "Wrong hormone or insulin doses can kill quickly.",
        "Diabetes and weight-related conditions carry stigma and blame."
      ],
      "affected_parties": [
        "Patients",
        "Carers and families"
      ]
    },
    "owners": {
      "steward": "The patient, with their treating clinicians; health services hold the records.",
      "master_systems": []
    }
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q2661443: endocrine system disease",
      "url": "https://www.wikidata.org/wiki/Q2661443",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Endocrine disease",
      "url": "https://en.wikipedia.org/wiki/Endocrine_disease",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "emergency",
        "name": "Emergency",
        "description": "Crises.",
        "rationale": "Some endocrine states are emergencies.",
        "layers": [
          {
            "id": "signs",
            "name": "Signs",
            "description": "Emergency signs.",
            "findings": [
              {
                "id": "signs-finding",
                "name": "Signs",
                "description": "Emergency signs.",
                "questions": [
                  {
                    "text": "Are there signs of an endocrine emergency such as severe hypoglycaemia, adrenal crisis or thyroid storm?",
                    "kind": "boundary"
                  },
                  {
                    "text": "Should emergency services be called now?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "sickday",
            "name": "Sick day",
            "description": "Sick day rules.",
            "findings": [
              {
                "id": "sickday-finding",
                "name": "Sick day",
                "description": "Sick day rules.",
                "questions": [
                  {
                    "text": "Does the person have sick day rules from their care team?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Who should they contact?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "understand",
        "name": "Understand",
        "description": "The diseases.",
        "rationale": "General information.",
        "layers": [
          {
            "id": "which",
            "name": "Which",
            "description": "Disease category.",
            "findings": [
              {
                "id": "which-finding",
                "name": "Which",
                "description": "Category.",
                "questions": [
                  {
                    "text": "Which gland or hormone does this disease involve, in general terms?",
                    "kind": "definition"
                  },
                  {
                    "text": "Is the user asking about their own results?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "tests",
            "name": "Tests",
            "description": "Diagnosis.",
            "findings": [
              {
                "id": "tests-finding",
                "name": "Tests",
                "description": "Diagnosis.",
                "questions": [
                  {
                    "text": "How are endocrine diseases diagnosed, according to guidelines?",
                    "kind": "provenance"
                  },
                  {
                    "text": "What do hormone tests measure?",
                    "kind": "definition"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "care",
        "name": "Care",
        "description": "Getting care.",
        "rationale": "Specialists manage care.",
        "layers": [
          {
            "id": "specialist",
            "name": "Specialist",
            "description": "Endocrinologists.",
            "findings": [
              {
                "id": "specialist-finding",
                "name": "Specialist",
                "description": "Specialists.",
                "questions": [
                  {
                    "text": "How can someone find an endocrinologist here?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which questions should be prepared?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "treatment",
            "name": "Treatment",
            "description": "Treatment types.",
            "findings": [
              {
                "id": "treatment-finding",
                "name": "Treatment",
                "description": "Treatment types.",
                "questions": [
                  {
                    "text": "Which treatment types are used, such as hormone replacement, medication or surgery, in general terms?",
                    "kind": "provenance"
                  },
                  {
                    "text": "What follow-up is typical?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "safety",
        "name": "Safety",
        "description": "Products and support.",
        "rationale": "Safety matters.",
        "layers": [
          {
            "id": "products",
            "name": "Products",
            "description": "Unregulated hormones.",
            "findings": [
              {
                "id": "products-finding",
                "name": "Products",
                "description": "Unregulated products.",
                "questions": [
                  {
                    "text": "Is this hormone product regulated and prescribed?",
                    "kind": "boundary"
                  },
                  {
                    "text": "What are the risks of unregulated hormones?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "orgs",
            "name": "Organisations",
            "description": "Patient groups.",
            "findings": [
              {
                "id": "orgs-finding",
                "name": "Organisations",
                "description": "Patient groups.",
                "questions": [
                  {
                    "text": "Which patient organisations support this condition?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which resources do they provide?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should each disease be a separate entry?",
    "How should guidelines be linked?",
    "How should specialists be localised?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}
