{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T09:16:06Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 19.6, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a094e5-f675-7e42-895f-e4f68492dfa2\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: DL-N-carbamoylaspartic acid\nSense to describe: (none recorded)\nDomain code: PHY.MAT\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Bat", "usd": 0.0, "recall": true }, "codex": { "seconds": 72.7, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a094e5-f670-74f2-a8c9-5b52e356ec23\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: DL-N-carbamoylaspartic acid\nRegistry id: vr.tr.dl-n-carbamoylaspartic-acid\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames f" } }, "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T12:00:00Z", "ingestedAt": "2026-10-06T08:43:02+00:00", "fields": [ "agent_conduct", "ethics", "failure_modes_and_hazards", "owners", "visual_identification" ] }, "revisions": [ { "at": "2026-10-07T11:28:41+00:00", "engine": "codex", "fields": [ "agent_conduct", "definition", "distinguishing_features", "in_scope", "purpose", "scope_statement" ], "answering_review": "4a0bfb018c41bb3e0ab03cec8c0faf3e351aec60eb8131f347651d022047329f" } ], "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T12:16:31+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q2823324", "registryId": "vr.tr.dl-n-carbamoylaspartic-acid", "name": "DL-N-carbamoylaspartic acid", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q2823324/", "model": { "registry_id": "vr.tr.dl-n-carbamoylaspartic-acid", "name": "DL-N-carbamoylaspartic acid", "purpose": "Enable an agent to recognise the N-carbamoylaspartic acid enantiomer group, distinguish group identity from sample composition, assess a material's identity and condition, and judge its suitability for a specified chemical or analytical use.", "definition": "DL-N-carbamoylaspartic acid denotes the group comprising the D and L enantiomers of N-carbamoylaspartic acid, an aspartic acid derivative whose amino nitrogen bears a carbamoyl group; membership in this group does not establish the enantiomer proportions of a material sample.", "scope_statement": "This model covers the N-carbamoylaspartic acid enantiomer group and its relationship to free-acid samples, distinguishing group membership from measured stereochemical composition, material quality, condition-dependent behaviour and evidence needed for handling decisions.", "in_scope": [ "N-carbamoylaspartic acid connectivity and the D and L members of the enantiomer group.", "Free-acid identity and relationships to ionised forms, salts and individual enantiomers.", "The distinction between group membership and a sample's enantiomer proportions.", "Lot-specific chemical purity, enantiomer proportions, water content and impurities.", "Solid and solution states under recorded conditions.", "Analytical suitability, storage evidence and substance-specific safety documentation." ], "out_of_scope": [ "Separate models of isolated D and L enantiomers", "Carbamoylaspartate salts as independently supplied substances", "Complete pyrimidine biosynthesis pathways and participating enzymes", "Manufacturing equipment and synthesis processes", "Formulated products containing this substance", "Therapeutic efficacy and clinical treatment protocols" ], "distinguishing_features": [ "The required connectivity is HOOC-CH(NH-CO-NH2)-CH2-COOH; the N-carbamoyl group distinguishes it from unmodified aspartic acid, as represented in the linked [PubChem record](https://pubchem.ncbi.nlm.nih.gov/compound/279).", "The group comprises the D and L enantiomers without requiring that a sample contain both or contain them in equal proportions.", "An achiral structure record alone cannot establish a sample's enantiomeric composition.", "Free-acid material must be distinguished from a supplied salt through counterion and composition evidence.", "Matching molecular mass alone does not establish connectivity, stereochemical composition or material grade.", "An unspecified ureidosuccinic acid record or an L-specific biochemical annotation cannot by itself establish the composition of a sample associated with this group." ], "characteristics": [ { "name": "Molecular composition", "kind": "category", "unit_or_values": "Free acid: C5H8N2O5; reference molar mass 176.13 g/mol. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/279)", "why_it_matters": "Supports identity checks and amount calculations once water, salt form and assay basis are established." }, { "name": "Identifier correspondence", "kind": "relation", "unit_or_values": "Candidate cross-references: CAS 923-37-5 and PubChem CID 279; verify their stereochemical scope. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/279)", "why_it_matters": "Prevents a synonym match from silently merging DL, unspecified and enantiomer-specific records." }, { "name": "Enantiomeric composition", "kind": "measurement", "unit_or_values": "D and L mole fractions or D:L ratio, with method and uncertainty", "why_it_matters": "Determines whether a lot supports the DL designation and a stereochemistry-sensitive use." }, { "name": "Chemical assay", "kind": "measurement", "unit_or_values": "Mass percent or amount fraction; as-received, dry or anhydrous basis", "why_it_matters": "Separates usable analyte content from water and other components." }, { "name": "Water and counterion content", "kind": "measurement", "unit_or_values": "Water mass percent; counterion identity and molar equivalents", "why_it_matters": "Tests free-acid identity and corrects gravimetric solution preparation." }, { "name": "Physical form", "kind": "state", "unit_or_values": "Observed solid form or solution, with temperature and preparation history", "why_it_matters": "Makes observations of dissolution and storage behaviour interpretable." }, { "name": "Solution condition", "kind": "measurement", "unit_or_values": "Concentration in mol/L, pH, solvent composition and temperature in °C", "why_it_matters": "Defines the conditions under which speciation and assay performance are evaluated." }, { "name": "Solubility and thermal behaviour", "kind": "measurement", "unit_or_values": "Solubility in g/L or mol/L; thermal events in °C, with method and decomposition assessment", "why_it_matters": "Supports preparation choices without treating unqualified catalogue values as universal constants." }, { "name": "Handling classification", "kind": "category", "unit_or_values": "Documented GHS classification, jurisdiction, SDS revision and evidence status", "why_it_matters": "Connects handling decisions to the actual material and distinguishes missing information from an assessed classification." } ], "affordances": [ "Match a labelled material to the registered substance using structure, stereochemical and counterion evidence.", "Calculate an assay-corrected amount for a target solution concentration.", "Select complementary identity, purity and chiral-composition measurements.", "Accept or reject a lot against requirements for a specified analytical or chemical use.", "Track condition changes and determine when reanalysis is needed.", "Retrieve applicable handling and disposal instructions from verified material documentation." ], "agent_conduct": { "may": [ "Identify the enantiomer group from its name, structure and identifiers without assuming a racemic sample.", "Distinguish the group from its individual members, including the L enantiomer that occurs in metabolism." ], "must_not": [ "Infer equal enantiomer proportions or sample equivalence to the biological L form from group membership alone.", "Report supplier data as batch measurements.", "Recommend human or animal use of a laboratory reagent." ], "requires_human": [ "Using the material in studies involving people or animals." ] }, "ethics": { "considerations": [ "Correct identification protects the validity of research results.", "Errors in chemical records spread through databases and papers." ], "affected_parties": [ "Researchers", "Laboratory staff" ] }, "owners": { "steward": "The laboratory or person holding the material; the supplier answers for its stated purity.", "master_systems": [ "Chemical substance databases" ] }, "visual_identification": [ "A white crystalline powder supplied in labelled containers, so the label and analysis settle identity.", "Enantiomeric composition can be told only by chiral analysis, not by appearance." ], "failure_modes_and_hazards": [ "Mislabelled stereochemistry can invalidate experiments.", "Fine powders can irritate the eyes and airways." ], "what_it_is_for": [ "DL-N-carbamoylaspartic acid is encountered in chemical and biochemical research involving carbamoylated amino acids.", "It can be used in analytical method development or studies that compare the behaviour of its D and L enantiomers.", "Its racemic composition matters in enzyme studies because the two enantiomers may not be accepted equally by a biological system." ], "standards_and_regulation": [ "The Globally Harmonized System of Classification and Labelling of Chemicals, issued by the United Nations, provides the framework for evaluating hazards and communicating any applicable classifications for supplied DL-N-carbamoylaspartic acid materials." ] }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q2823324: DL-N-carbamoylaspartic acid", "url": "https://www.wikidata.org/wiki/Q2823324", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Carbamoyl aspartic acid", "url": "https://en.wikipedia.org/wiki/Carbamoyl_aspartic_acid", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "chemical-identity-and-boundaries", "name": "Chemical identity and boundaries", "description": "Establishes which molecular entity and supplied material the DL name denotes.", "rationale": "Carbamoylaspartic acid names can obscure differences between connectivity, stereochemical scope and salt form.", "layers": [ { "id": "connectivity-and-identifiers", "name": "Connectivity and identifiers", "description": "Connects the registry name to structural evidence and qualified external identifiers.", "findings": [ { "id": "n-carbamoyl-connectivity", "name": "N-carbamoyl connectivity", "description": "Require evidence that the carbamoyl group is attached through the aspartic amino nitrogen.", "questions": [ { "text": "What structural evidence establishes HOOC-CH(NH-CO-NH2)-CH2-COOH for this material?", "kind": "definition", "id": "n-carbamoyl-connectivity-q01" }, { "text": "Which identifier records were checked, and do they describe DL material or stereochemistry-unspecified connectivity?", "kind": "provenance", "id": "n-carbamoyl-connectivity-q02" } ] } ] }, { "id": "free-acid-boundary", "name": "Free-acid boundary", "description": "Separates the supplied free acid from salts and solution-dependent ionic states.", "findings": [ { "id": "counterion-and-speciation-boundary", "name": "Counterion and speciation boundary", "description": "Record supplied composition separately from protonation changes following dissolution.", "questions": [ { "text": "Does counterion analysis support a free acid, a salt or a mixture?", "kind": "measurement", "id": "counterion-and-speciation-boundary-q01" }, { "text": "When neutralisation is performed, which resulting salt or solution record should be linked to this substance?", "kind": "boundary", "id": "counterion-and-speciation-boundary-q02" } ] } ] } ] }, { "id": "dl-composition-and-biochemical-relevance", "name": "DL composition and biochemical relevance", "description": "Makes enantiomer proportions explicit and limits transfer of enantiomer-specific evidence.", "rationale": "The DL designation is central to this entry, while a chemical identity assay may not resolve enantiomers.", "layers": [ { "id": "enantiomer-proportions", "name": "Enantiomer proportions", "description": "Distinguishes an asserted DL label from demonstrated stereochemical composition.", "findings": [ { "id": "racemate-verification", "name": "Racemate verification", "description": "Treat nominal racemic composition and measured D:L ratio as separate records.", "questions": [ { "text": "What D:L ratio and uncertainty were measured using a method that resolves the enantiomers?", "kind": "measurement", "id": "racemate-verification-q01" }, { "text": "What tolerance around equal proportions defines acceptable DL material for the intended use?", "kind": "definition", "id": "racemate-verification-q02" }, { "text": "How were the D and L analytical signals assigned?", "kind": "provenance", "id": "racemate-verification-q03" } ] } ] }, { "id": "stereospecific-use", "name": "Stereospecific use", "description": "Qualifies applications whose response may depend on the individual enantiomer.", "findings": [ { "id": "biochemical-evidence-transfer", "name": "Biochemical evidence transfer", "description": "Require explicit justification before applying enantiomer-specific reaction evidence to a DL sample.", "questions": [ { "text": "Does the cited assay or reaction study use DL material, isolated L material or an unspecified form?", "kind": "provenance", "id": "biochemical-evidence-transfer-q01" }, { "text": "Must the working concentration be expressed as total carbamoylaspartic acid or as a measured individual-enantiomer concentration?", "kind": "action", "id": "biochemical-evidence-transfer-q02" } ] } ] } ] }, { "id": "lot-composition-and-analytical-confidence", "name": "Lot composition and analytical confidence", "description": "Determines how much of the weighed material is the intended substance and how confidently it is identified.", "rationale": "Chemical purity, water content and stereochemical purity answer different acceptance questions.", "layers": [ { "id": "assay-and-impurities", "name": "Assay and impurities", "description": "Qualifies reported content and investigates route-relevant contaminants.", "findings": [ { "id": "usable-analyte-content", "name": "Usable analyte content", "description": "Require an assay basis and targeted evidence for plausible impurities rather than interpreting peak area as mass purity.", "questions": [ { "text": "Is the reported content a calibrated assay, chromatographic area percentage or acid-base titration result?", "kind": "measurement", "id": "usable-analyte-content-q01" }, { "text": "What evidence addresses residual aspartic acid, urea or other impurities suggested by the documented preparation route?", "kind": "provenance", "id": "usable-analyte-content-q02" }, { "text": "How are water and residual solvent accounted for in the usable analyte amount?", "kind": "measurement", "id": "usable-analyte-content-q03" } ] } ] }, { "id": "orthogonal-identification", "name": "Orthogonal identification", "description": "Combines methods whose limitations are explicit.", "findings": [ { "id": "identity-evidence-coverage", "name": "Identity evidence coverage", "description": "Assess connectivity, bulk composition and enantiomer proportions through appropriate complementary measurements.", "questions": [ { "text": "Which NMR, mass-spectral or other observations distinguish the intended connectivity from plausible alternatives?", "kind": "measurement", "id": "identity-evidence-coverage-q01" }, { "text": "Which identity questions remain unresolved by the available achiral measurements?", "kind": "boundary", "id": "identity-evidence-coverage-q02" } ] } ] } ] }, { "id": "physical-state-and-solution-preparation", "name": "Physical state and solution preparation", "description": "Captures the conditions needed to weigh, dissolve and maintain a usable preparation.", "rationale": "A free-acid formula alone cannot establish dissolved concentration, solid form or thermal behaviour.", "layers": [ { "id": "solid-and-thermal-state", "name": "Solid and thermal state", "description": "Records observed material form and qualified thermal measurements.", "findings": [ { "id": "solid-form-and-thermal-events", "name": "Solid form and thermal events", "description": "Distinguish measured melting, water loss and decomposition rather than assigning an unsupported thermal constant.", "questions": [ { "text": "What evidence establishes the lot's water content and crystalline or amorphous state?", "kind": "measurement", "id": "solid-form-and-thermal-events-q01" }, { "text": "What thermal events were observed, at what heating rate, and were they attributed to melting or decomposition?", "kind": "measurement", "id": "solid-form-and-thermal-events-q02" } ] } ] }, { "id": "dissolution-and-ionisation", "name": "Dissolution and ionisation", "description": "Defines solution conditions and resulting composition.", "findings": [ { "id": "qualified-solution-concentration", "name": "Qualified solution concentration", "description": "Tie achievable concentration and protonation assessments to measured conditions.", "questions": [ { "text": "What equilibrium solubility is supported for the chosen solvent, temperature and pH?", "kind": "measurement", "id": "qualified-solution-concentration-q01" }, { "text": "What acid-dissociation evidence supports the proposed protonation distribution under those conditions?", "kind": "provenance", "id": "qualified-solution-concentration-q02" }, { "text": "What assay correction and added-base record are required to prepare the target concentration reproducibly?", "kind": "action", "id": "qualified-solution-concentration-q03" } ] } ] } ] }, { "id": "stability-and-authorised-handling", "name": "Stability and handling decisions", "description": "Connects storage, transformation monitoring and handling requirements to evidence for the actual material.", "rationale": "Use decisions require substance-specific stability and safety evidence beyond the DL name.", "layers": [ { "id": "storage-and-transformation", "name": "Storage and transformation", "description": "Tracks whether the material retains its qualified composition during storage and use.", "findings": [ { "id": "retained-chemical-and-chiral-quality", "name": "Retained chemical and chiral quality", "description": "Investigate possible hydrolysis, cyclisation or changes in enantiomer proportions without presuming their occurrence.", "questions": [ { "text": "What stability data support the specified solid-storage conditions and solution holding time?", "kind": "provenance", "id": "retained-chemical-and-chiral-quality-q01" }, { "text": "Do measurements show hydrolysis, cyclisation products or a changed D:L ratio after the intended exposure conditions?", "kind": "measurement", "id": "retained-chemical-and-chiral-quality-q02" }, { "text": "Which measured changes require requalification or rejection?", "kind": "action", "id": "retained-chemical-and-chiral-quality-q03" } ] } ] }, { "id": "hazard-and-regulatory-evidence", "name": "Hazard and regulatory evidence", "description": "Matches handling instructions and regulatory identity to the supplied DL material.", "findings": [ { "id": "material-specific-handling-basis", "name": "Material-specific handling basis", "description": "Record documented classifications and evidence gaps without interpreting missing hazard data as safety.", "questions": [ { "text": "Which current SDS and jurisdictional identifiers explicitly match this free-acid DL material?", "kind": "provenance", "id": "material-specific-handling-basis-q01" }, { "text": "What GHS classification and exposure-limit information are documented, absent or unresolved?", "kind": "definition", "id": "material-specific-handling-basis-q02" }, { "text": "What controls, incompatibility restrictions and disposal route apply to the planned quantity and operation?", "kind": "action", "id": "material-specific-handling-basis-q03" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "The molecular formula is C5H8N2O5; the molar mass given applies to the neutral, anhydrous compound.", "Verify registry identifiers against the racemate specifically, distinguishing it from individual enantiomers, salts and hydrates.", "Specific uses, physical constants, purity specifications and hazard classifications require source verification; none were consulted for this recall." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of DL-N-carbamoylaspartic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "IUPAC nomenclature", "value_or_pattern": "2-(carbamoylamino)butanedioic acid", "note": "This name describes the connectivity; the DL designation additionally specifies the racemate." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of DL-N-carbamoylaspartic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Research involving carbamoylated amino acids and stereoselectivity in reactions related to pyrimidine biosynthesis." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of DL-N-carbamoylaspartic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Molar mass", "typical_range": "176.13", "unit": "g/mol" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of DL-N-carbamoylaspartic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Substituting the DL mixture for the L enantiomer can confound enzyme assays because biological activity may be stereoselective." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of DL-N-carbamoylaspartic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "N-carbamoyl-L-aspartic acid", "difference": "The L enantiomer alone is an intermediate in de novo pyrimidine biosynthesis; the DL substance contains both enantiomers." }, { "name": "N-carbamoyl-D-aspartic acid", "difference": "The D enantiomer alone has the opposite configuration to the L form; it is one component of the DL mixture." }, { "name": "Aspartic acid", "difference": "Its amino nitrogen lacks the carbamoyl substituent." }, { "name": "N-carbamoylaspartate", "difference": "This denotes a deprotonated form rather than the fully protonated acid; the name alone does not establish stereochemistry." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of DL-N-carbamoylaspartic acid this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Does the authoritative registry intend a strictly racemic substance or a broader stereochemistry-unspecified entity, and how should overlapping external identifiers be qualified?", "Which reference method and acceptance tolerance establish the D:L ratio for available material?", "What verified solubility, acid-dissociation and thermal data apply to a characterised DL free-acid sample?", "Which storage and solution conditions preserve chemical assay and enantiomer proportions, and which transformation products have actually been observed?", "Which current primary safety and regulatory records establish the EC identity, GHS classification and any applicable exposure limits for the exact material?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 16, "questions": 31 } }