{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-13T05:16:09Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 3,
    "engine": "claude",
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-06T10:00:00Z",
      "ingestedAt": "2026-10-06T07:05:49+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "owners"
      ]
    },
    "revisions": [
      {
        "at": "2026-10-06T22:47:09+00:00",
        "engine": "codex",
        "fields": [
          "definition",
          "distinguishing_features"
        ],
        "answering_review": "b9f1ee5b571ca626f05ecf88acdaa99f471669a8ffb290527f549d7a1ff6ff1e"
      }
    ],
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-07T10:10:29+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q2832080",
    "registryId": "vr.tr.tropane-alkaloids",
    "name": "tropane alkaloids",
    "version": "0.2.0-wave.3",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "PHY.MAT"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q2832080/",
  "model": {
    "registry_id": "vr.tr.tropane-alkaloids",
    "name": "tropane alkaloids",
    "purpose": "Let an agent explain tropane alkaloids and their sources, relay pharmacology, medical uses and toxicity in general from pharmacology references, describe food safety and regulation, route suspected poisonings to emergency services, and decline extraction, synthesis or recreational use detail.",
    "definition": "A class of alkaloids containing the bicyclic tropane ring, produced mainly by plants of the nightshade family such as belladonna, henbane, datura and mandrake and by coca, including atropine and its natural form hyoscyamine, scopolamine, cocaine, and the polyhydroxylated calystegines found in bindweeds, potatoes and other plants, while some registry aliases such as stemofoline belong to other alkaloid classes; some tropane alkaloids act on acetylcholine or monoamine systems, whereas calystegines inhibit glycosidases, and members of the class include medicines for eye examination, motion sickness and anaesthesia, toxic substances and controlled substances.",
    "what_it_is_for": "Not applicable; a chemical class.",
    "affordances": [
      "explain the class and sources",
      "relay pharmacology and uses",
      "describe toxicity and regulation",
      "route poisonings and decline misuse detail"
    ],
    "distinguishing_features": [
      "Members contain a tropane ring.",
      "Many members originate in nightshade plants.",
      "Some members have anticholinergic or stimulant action, whereas calystegines inhibit glycosidases.",
      "The class includes medicines and poisons."
    ],
    "appearance": "Not a visible object; compounds in nightshade plants.",
    "visual_identification": [
      "Alkaloids with a tropane ring",
      "Atropine, hyoscyamine, scopolamine, cocaine, calystegines",
      "Stemofoline is a Stemona alkaloid; nicotine is a pyridine alkaloid; opioids are a separate class"
    ],
    "physical_properties": [
      {
        "quantity": "core structure",
        "typical_range": "8-azabicyclo[3.2.1]octane",
        "unit": "formula",
        "note": "tropane"
      },
      {
        "quantity": "main plant family",
        "typical_range": "Solanaceae",
        "unit": "family",
        "note": ""
      },
      {
        "quantity": "atropine on WHO essential list",
        "typical_range": "yes",
        "unit": "note",
        "note": ""
      }
    ],
    "families_and_kinds": [
      "anticholinergic tropanes such as atropine, hyoscyamine and scopolamine",
      "cocaine and related coca alkaloids",
      "calystegines as glycosidase inhibitors",
      "semi-synthetic derivatives used as medicines",
      "misfiled aliases such as stemofoline that belong to Stemona alkaloids"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "alkaloid",
        "why": "in registry terms"
      },
      {
        "relation": "is a kind of",
        "target": "tropane",
        "why": "derivatives in registry terms"
      },
      {
        "relation": "is produced by",
        "target": "Solanaceae",
        "why": "and coca plants"
      },
      {
        "relation": "is exemplified by",
        "target": "atropine",
        "why": "an essential medicine"
      }
    ],
    "identifiers": [],
    "standards_and_regulation": [
      "Medicines regulation for atropine, scopolamine and related drugs",
      "Controlled substance laws for cocaine",
      "EU maximum levels for tropane alkaloids in food such as cereals"
    ],
    "failure_modes_and_hazards": [
      "Poisoning from plants and contaminated food",
      "Agents providing extraction, synthesis or misuse detail",
      "Agents giving personal medical advice",
      "Misfiled aliases from other alkaloid classes"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": [],
    "agent_conduct": {
      "may": [
        "Explain tropane alkaloids as a chemical class and name the plants that produce them, citing pharmacology sources.",
        "Relay approved medical uses of drugs in this class, such as atropine, from official drug references.",
        "Warn that the plants that contain them are poisonous and that suspected poisoning needs emergency care."
      ],
      "must_not": [
        "Provide any information on extracting, refining or preparing these alkaloids from plants.",
        "Advise on doses for non-medical, recreational or harmful use.",
        "Assist in giving any of these substances to a person without their knowledge or consent.",
        "Help produce, traffic or conceal controlled substances in this class."
      ],
      "requires_human": [
        "Any advice that could affect the treatment of a person who may be poisoned, beyond directing them to emergency services."
      ]
    },
    "ethics": {
      "considerations": [
        "Some members are life-saving medicines while others are abused or used to incapacitate victims.",
        "Accidental poisoning from garden and wild plants affects children and foragers."
      ],
      "affected_parties": [
        "Patients",
        "Children and foragers",
        "Victims of covert drugging"
      ]
    },
    "owners": {
      "steward": "Nobody owns the class; medicines regulators and drug control authorities govern the controlled members.",
      "master_systems": []
    }
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q2832080: tropane alkaloids",
      "url": "https://www.wikidata.org/wiki/Q2832080",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Tropane alkaloid",
      "url": "https://en.wikipedia.org/wiki/Tropane_alkaloid",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "help",
        "name": "Help",
        "description": "Poisoning first.",
        "rationale": "Safety.",
        "layers": [
          {
            "id": "poisoning",
            "name": "Poisoning",
            "description": "Suspected poisoning.",
            "findings": [
              {
                "id": "poisoning-finding",
                "name": "Poisoning",
                "description": "Poisoning.",
                "questions": [
                  {
                    "text": "Why does suspected ingestion of nightshade plants or contaminated food with symptoms such as dilated pupils, confusion, rapid heartbeat or hallucinations need emergency services or poison control immediately?",
                    "kind": "action"
                  },
                  {
                    "text": "Is the user describing a suspected poisoning now, which needs emergency services?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "food",
            "name": "Food",
            "description": "Food contamination.",
            "findings": [
              {
                "id": "food-finding",
                "name": "Food",
                "description": "Food.",
                "questions": [
                  {
                    "text": "How do tropane alkaloids contaminate cereals and other foods, and what limits apply?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits food contaminant?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "understand",
        "name": "Understand",
        "description": "The class.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "definition",
            "name": "Definition",
            "description": "Definition and sources.",
            "findings": [
              {
                "id": "definition-finding",
                "name": "Definition",
                "description": "Definition.",
                "questions": [
                  {
                    "text": "What are tropane alkaloids, which plants produce them, and which registry aliases belong elsewhere?",
                    "kind": "definition"
                  },
                  {
                    "text": "Is the question about the class, a specific compound, or extraction and misuse the model does not cover?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "members",
            "name": "Members",
            "description": "Members.",
            "findings": [
              {
                "id": "members-finding",
                "name": "Members",
                "description": "Members.",
                "questions": [
                  {
                    "text": "How do atropine, hyoscyamine, scopolamine, cocaine and calystegines differ in structure and action?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which entry fits the specific compound?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "medicine",
        "name": "Medicine",
        "description": "Pharmacology and medicine.",
        "rationale": "Clinical.",
        "layers": [
          {
            "id": "pharmacology",
            "name": "Pharmacology",
            "description": "Pharmacology.",
            "findings": [
              {
                "id": "pharmacology-finding",
                "name": "Pharmacology",
                "description": "Pharmacology.",
                "questions": [
                  {
                    "text": "How do tropane alkaloids act on receptors and transporters, in general terms?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which references are standard?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "uses",
            "name": "Uses",
            "description": "Medical uses.",
            "findings": [
              {
                "id": "uses-finding",
                "name": "Uses",
                "description": "Uses.",
                "questions": [
                  {
                    "text": "How are atropine, scopolamine and derivatives used in medicine, in general terms?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Is the user asking about their own treatment, which needs a clinician?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "context",
        "name": "Context",
        "description": "History and biosynthesis.",
        "rationale": "Context.",
        "layers": [
          {
            "id": "history",
            "name": "History",
            "description": "History.",
            "findings": [
              {
                "id": "history-finding",
                "name": "History",
                "description": "History.",
                "questions": [
                  {
                    "text": "How have nightshade alkaloids figured in history, from medicine to poisons and folklore, as historians describe?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits the history of pharmacology?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "biosynthesis",
            "name": "Biosynthesis",
            "description": "Biosynthesis.",
            "findings": [
              {
                "id": "biosynthesis-finding",
                "name": "Biosynthesis",
                "description": "Biosynthesis.",
                "questions": [
                  {
                    "text": "How do plants make tropane alkaloids, and why?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits alkaloid biosynthesis?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should atropine and calystegine be separate primary entries?",
    "How should pharmacology references be linked?",
    "The registry entry has merged aliases including Stemona alkaloids that are not tropanes; should they be removed?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}