{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T11:45:20Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 19.9, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a0956e-60d6-7d91-a8ad-3dfbe97819f6\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: oophoritis\nSense to describe: (none recorded)\nDomain code: XCT.STA\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Batch 044: 1001 regi", "usd": 0.0, "recall": true }, "codex": { "seconds": 86.3, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a0956e-60e3-78f0-81c5-51d8d420bf3b\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: oophoritis\nRegistry id: vr.tr.oophoritis\nPlane / domain: XCT / XCT.STA\nRegistry definition: (none recorded)\nNames folded into this entry: (none)\n\n\nCo" } }, "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T12:00:00Z", "ingestedAt": "2026-10-06T08:46:50+00:00", "fields": [ "agent_conduct", "ethics", "failure_modes_and_hazards", "owners" ] }, "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T10:10:29+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q2851545", "registryId": "vr.tr.oophoritis", "name": "oophoritis", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.STA" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q2851545/", "model": { "registry_id": "vr.tr.oophoritis", "name": "oophoritis", "purpose": "Enable an agent to recognise and characterise oophoritis, assess the evidence for ovarian inflammation and its consequences, and identify appropriate clinician-led evaluation and follow-up.", "definition": "Oophoritis is inflammation of ovarian tissue, which may arise from infection or autoimmune injury and may occur alone or alongside inflammation of adjacent reproductive organs.", "scope_statement": "This model owns oophoritis as an inflammatory condition of ovarian tissue under vr.tr.oophoritis in XCT / XCT.STA, including anatomical extent, aetiological attribution, diagnostic uncertainty, activity and ovarian consequences; it distinguishes the condition from a diagnostic assertion and an episode of care.", "in_scope": [ "Evidence localising inflammation to one or both ovaries", "Infectious, autoimmune, other specified and unresolved aetiological attributions", "Isolated ovarian involvement versus associated tubal or wider pelvic inflammation", "Diagnostic assertions, supporting observations and versioned classification mappings", "Inflammatory course, complications and attributable ovarian functional effects", "Evidence needed to select and reassess clinician-led management" ], "out_of_scope": [ "The patient's complete medical, reproductive or sexual history", "Pelvic inflammatory disease and salpingitis beyond their relationship to ovarian involvement", "Standalone models of ovarian torsion, cysts, endometriosis and neoplasms", "Primary ovarian insufficiency or infertility without evidence of ovarian inflammation", "Detailed antimicrobial, immunomodulatory or surgical treatment protocols", "Appointments, admissions, billing and other care-episode administration" ], "distinguishing_features": [ "Require evidence or an explicit clinical hypothesis of ovarian tissue inflammation; pelvic pain or an adnexal abnormality alone does not establish oophoritis.", "Distinguish ovarian involvement from inflammation confined to a fallopian tube; a broader pelvic inflammatory disease label does not by itself establish isolated oophoritis.", "Record an ovarian or tubo-ovarian abscess separately as a demonstrated collection, rather than treating every inflammatory ovarian finding as an abscess.", "Distinguish inflammatory ovarian disease from ovarian dysfunction: impaired hormone production or fertility alone does not establish an inflammatory cause.", "Separate autoimmune attribution from infectious attribution and from unresolved cause, retaining the evidence and uncertainty supporting each." ], "characteristics": [ { "name": "Ovarian localisation", "kind": "category", "unit_or_values": "Left; right; bilateral; ovarian involvement suspected but side unresolved", "why_it_matters": "Identifies the affected tissue and prevents a nonspecific pelvic finding from becoming an unsupported ovarian diagnosis." }, { "name": "Anatomical extent", "kind": "category", "unit_or_values": "Apparently isolated ovarian; associated tubal; wider pelvic; unresolved", "why_it_matters": "Separates oophoritis from overlapping salpingo-oophoritis and pelvic inflammatory disease." }, { "name": "Diagnostic assertion status", "kind": "state", "unit_or_values": "Suspected; supported; confirmed under an explicitly cited standard; disputed; excluded", "why_it_matters": "Preserves the difference between a condition label and the strength of evidence supporting it." }, { "name": "Aetiological attribution", "kind": "category", "unit_or_values": "Infectious; autoimmune; other specified; unresolved; multiple hypotheses retained", "why_it_matters": "Management reasoning depends on cause, which must not be inferred from the name alone." }, { "name": "Evidence basis", "kind": "relation", "unit_or_values": "Dated clinical assessment, imaging, microbiology, histopathology or immune investigation, with source and limitations", "why_it_matters": "Allows an agent to distinguish direct ovarian evidence from indirect support." }, { "name": "Inflammatory course", "kind": "state", "unit_or_values": "Onset date or interval; clinician-described acute, persistent or recurrent course; improving, worsening, resolved or unknown activity", "why_it_matters": "Tracks change without inventing universal oophoritis stages or duration thresholds." }, { "name": "Associated collection", "kind": "measurement", "unit_or_values": "Dimensions in mm, anatomical location, imaging date and method; absent, present or indeterminate", "why_it_matters": "Supports assessment of a documented ovarian or tubo-ovarian collection and its evolution." }, { "name": "Ovarian functional consequence", "kind": "relation", "unit_or_values": "Linked menstrual, endocrine, ovarian-reserve or fertility assessment, with date and attribution confidence", "why_it_matters": "Separates current inflammation from possible persistent functional damage." }, { "name": "Classification mapping", "kind": "relation", "unit_or_values": "Verified code, label, terminology, release or revision, jurisdiction and mapping breadth", "why_it_matters": "Prevents a combined salpingitis-and-oophoritis code from being mistaken for a precise anatomical diagnosis." } ], "affordances": [ "Assemble an evidence-qualified account of ovarian inflammation and identify missing localisation evidence.", "Compare infectious, autoimmune and alternative explanations without promoting a hypothesis to a confirmed cause.", "Link associated pelvic disease, abscess or ovarian dysfunction while preserving their distinct identities.", "Flag documented deterioration or complications for clinician review using an applicable, cited clinical pathway.", "Track inflammatory activity and ovarian function separately across reassessments.", "Map the condition to verified terminology releases while exposing broader or imperfect code matches." ], "agent_conduct": { "may": [ "Describe oophoritis, its causes and treatment from medical sources.", "Point people with pelvic pain or fertility concerns to clinicians." ], "must_not": [ "Diagnose oophoritis or another gynaecological condition from symptoms without a clinician.", "Advise treatment or antibiotics.", "Disclose a person's reproductive health information without consent.", "Stigmatize people with sexually transmitted infections that can cause it." ], "requires_human": [ "Responding to severe pelvic pain that may need emergency care." ] }, "ethics": { "considerations": [ "Reproductive health information is deeply private and can lead to stigma.", "Delayed care for pelvic infections can damage fertility." ], "affected_parties": [ "Patients", "Partners" ] }, "owners": { "steward": "Nobody owns the condition; the treating clinician answers for each patient's care.", "master_systems": [] }, "failure_modes_and_hazards": [ "Untreated infection can cause abscesses and infertility.", "Autoimmune forms can lead to early loss of ovarian function." ], "what_it_is_for": [ "Oophoritis is encountered in clinical evaluation of ovarian inflammation associated with infection or autoimmune injury.", "The diagnosis helps clinicians investigate pelvic symptoms, reproductive consequences and possible involvement of adjacent organs." ], "standards_and_regulation": [ "The International Classification of Diseases, Tenth Revision, issued by the World Health Organization, includes salpingitis and oophoritis under category N70." ], "facets_not_applicable": { "recognition": "Oophoritis has no reliable external visual signature, and identification requires clinical evidence rather than appearance alone." } }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q2851545: oophoritis", "url": "https://www.wikidata.org/wiki/Q2851545", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Oophoritis", "url": "https://en.wikipedia.org/wiki/Oophoritis", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "ovarian-localisation-and-boundaries", "name": "Ovarian localisation and boundaries", "description": "Establish whether ovarian tissue is involved and how the condition relates to neighbouring pelvic disorders.", "rationale": "Oophoritis loses its identity if any pelvic inflammation or ovarian abnormality is accepted as equivalent.", "layers": [ { "id": "ovarian-tissue-involvement", "name": "Ovarian tissue involvement", "description": "Locate the inflammatory process and preserve uncertainty about side and tissue.", "findings": [ { "id": "localisation-evidence", "name": "Localisation evidence", "description": "Record the observation supporting ovarian inflammation, its laterality and whether localisation is direct or inferred.", "questions": [ { "text": "What observation supports inflammation within ovarian tissue rather than nonspecific adnexal or pelvic inflammation?", "kind": "boundary", "id": "localisation-evidence-q01" }, { "text": "Which ovary is implicated, by which examination or report, and on what date?", "kind": "provenance", "id": "localisation-evidence-q02" } ] } ] }, { "id": "adjacent-pelvic-disease", "name": "Adjacent pelvic disease", "description": "Describe tubal and wider pelvic involvement without collapsing related conditions.", "findings": [ { "id": "extent-and-related-diagnoses", "name": "Extent and related diagnoses", "description": "Record whether ovarian involvement is isolated or accompanies a broader process. PID encompasses multiple upper genital tract inflammatory disorders and is not a precise ovarian localisation. [CDC PID guideline](https://www.cdc.gov/std/treatment-guidelines/pid.htm).", "questions": [ { "text": "Is tubal or wider pelvic involvement demonstrated, suspected, absent or unassessed?", "kind": "boundary", "id": "extent-and-related-diagnoses-q01" }, { "text": "Does a related PID, salpingitis or abscess diagnosis describe additional disease or merely repeat the same uncertain finding?", "kind": "definition", "id": "extent-and-related-diagnoses-q02" } ] } ] } ] }, { "id": "cause-and-inflammatory-pattern", "name": "Cause and inflammatory pattern", "description": "Represent the proposed cause and the evidence distinguishing infection from immune-mediated or unresolved inflammation.", "rationale": "An ovarian inflammatory label alone cannot justify a causal claim or a treatment pathway.", "layers": [ { "id": "infectious-attribution", "name": "Infectious attribution", "description": "Connect suspected infection to specimens, organisms and anatomical plausibility.", "findings": [ { "id": "organism-and-specimen-link", "name": "Organism and specimen link", "description": "Keep evidence of infection at another genital site distinct from evidence identifying the cause of ovarian inflammation.", "questions": [ { "text": "Which organism is suspected or detected, using what assay, specimen site and collection date?", "kind": "provenance", "id": "organism-and-specimen-link-q01" }, { "text": "What supports attributing ovarian inflammation to that result rather than to a coincident infection?", "kind": "boundary", "id": "organism-and-specimen-link-q02" }, { "text": "Was sampling performed before or after treatment that could affect interpretation?", "kind": "provenance", "id": "organism-and-specimen-link-q03" } ] } ] }, { "id": "autoimmune-and-other-attribution", "name": "Autoimmune and other attribution", "description": "Evaluate noninfectious hypotheses without equating ovarian dysfunction or autoimmunity elsewhere with proven oophoritis.", "findings": [ { "id": "immune-mediated-evidence", "name": "Immune-mediated evidence", "description": "Record pathology and immune findings with their diagnostic limits. A primary histopathological study documents an inflammatory cellular infiltrate in autoimmune oophoritis; this does not establish a universal noninvasive diagnostic rule. [Histopathological study](https://pubmed.ncbi.nlm.nih.gov/3570633/).", "questions": [ { "text": "What ovarian-specific evidence supports autoimmune inflammation, and what evidence is only indirect?", "kind": "provenance", "id": "immune-mediated-evidence-q01" }, { "text": "If tissue was already obtained for a clinical indication, what inflammatory pattern was reported and how was it interpreted?", "kind": "definition", "id": "immune-mediated-evidence-q02" }, { "text": "Which infectious, other specified or unresolved explanations remain viable?", "kind": "boundary", "id": "immune-mediated-evidence-q03" } ] } ] } ] }, { "id": "diagnostic-evidence-and-classification", "name": "Diagnostic evidence and classification", "description": "Make the diagnostic assertion auditable and distinguish it from symptom descriptions and coding conventions.", "rationale": "Clinical, imaging and pathological uses of the label may carry different levels of certainty.", "layers": [ { "id": "assertion-and-differential", "name": "Assertion and differential", "description": "Capture the basis of diagnosis and unresolved competing explanations.", "findings": [ { "id": "diagnostic-justification", "name": "Diagnostic justification", "description": "Attach the oophoritis assertion to an accountable interpretation of evidence rather than to an isolated symptom or test.", "questions": [ { "text": "Who asserted oophoritis, when, and with what stated degree of certainty?", "kind": "provenance", "id": "diagnostic-justification-q01" }, { "text": "What supports inflammation over torsion, a haemorrhagic cyst, endometriosis or neoplasm in this presentation?", "kind": "boundary", "id": "diagnostic-justification-q02" }, { "text": "Which evidence would materially change the diagnostic assessment?", "kind": "action", "id": "diagnostic-justification-q03" } ] } ] }, { "id": "criteria-and-terminology-version", "name": "Criteria and terminology version", "description": "Separate clinical criteria from the terminology used to encode the condition.", "findings": [ { "id": "versioned-diagnostic-mapping", "name": "Versioned diagnostic mapping", "description": "Record applicable criteria and verified ICD or SNOMED mappings with their issuer, release and scope; leave unavailable mappings unresolved.", "questions": [ { "text": "Which issuing body and document version support the diagnostic criteria being applied, if any?", "kind": "provenance", "id": "versioned-diagnostic-mapping-q01" }, { "text": "What verified code and release represent this condition in the relevant jurisdiction?", "kind": "provenance", "id": "versioned-diagnostic-mapping-q02" }, { "text": "Does the code specifically represent oophoritis or combine it with salpingitis, chronicity or another broader category?", "kind": "boundary", "id": "versioned-diagnostic-mapping-q03" } ] } ] } ] }, { "id": "activity-and-ovarian-consequences", "name": "Activity and ovarian consequences", "description": "Track the inflammatory process separately from associated collections and ovarian functional outcomes.", "rationale": "Improvement in inflammation does not by itself establish recovery of ovarian function.", "layers": [ { "id": "temporal-course-and-complications", "name": "Temporal course and complications", "description": "Represent dated changes and explicitly demonstrated complications.", "findings": [ { "id": "activity-and-collection-trend", "name": "Activity and collection trend", "description": "Record the evidence used to judge persistence, improvement or deterioration, including any ovarian or tubo-ovarian collection.", "questions": [ { "text": "What dates and observations support the reported onset, persistence, recurrence or resolution?", "kind": "measurement", "id": "activity-and-collection-trend-q01" }, { "text": "If a collection is present, what are its location, dimensions and change on comparable examinations?", "kind": "measurement", "id": "activity-and-collection-trend-q02" }, { "text": "Which complications are demonstrated, which are suspected, and which have not been assessed?", "kind": "definition", "id": "activity-and-collection-trend-q03" } ] } ] }, { "id": "ovarian-function-and-attribution", "name": "Ovarian function and attribution", "description": "Assess reproductive and endocrine consequences without assuming they establish the inflammatory diagnosis.", "findings": [ { "id": "functional-outcome-evidence", "name": "Functional outcome evidence", "description": "Link functional assessments and qualify causal attribution. Autoimmune oophoritis has been described as a cause of ovarian failure, but an individual functional deficit still requires attribution evidence. [Autoimmune oophoritis study](https://pubmed.ncbi.nlm.nih.gov/6691297/).", "questions": [ { "text": "What menstrual, endocrine or fertility changes are documented relative to the precondition baseline?", "kind": "measurement", "id": "functional-outcome-evidence-q01" }, { "text": "What supports attributing these changes to ovarian inflammation rather than another ovarian, tubal or systemic cause?", "kind": "boundary", "id": "functional-outcome-evidence-q02" }, { "text": "Were functional observations interpreted with age, reproductive stage, medications and assay reference information?", "kind": "provenance", "id": "functional-outcome-evidence-q03" } ] } ] } ] }, { "id": "clinical-action-and-reassessment", "name": "Clinical action and reassessment", "description": "Connect uncertainty, severity and suspected cause to an accountable clinical plan and subsequent review.", "rationale": "An agent must recognise when the current evidence warrants review and what observations would establish response.", "layers": [ { "id": "urgency-and-management-basis", "name": "Urgency and management basis", "description": "Record the reason for escalation and the clinical pathway selected for the documented presentation.", "findings": [ { "id": "review-and-pathway-selection", "name": "Review and pathway selection", "description": "Link clinician-led decisions to suspected cause, complication status and an applicable guideline. For associated PID, CDC guidance identifies tubo-ovarian abscess and severe illness among considerations for hospitalisation. [CDC PID guideline](https://www.cdc.gov/std/treatment-guidelines/pid.htm).", "questions": [ { "text": "Do documented findings trigger urgent review under the cited pathway, and who is responsible for that review?", "kind": "action", "id": "review-and-pathway-selection-q01" }, { "text": "What evidence supports the selected infectious, immune-focused or further-investigation pathway?", "kind": "action", "id": "review-and-pathway-selection-q02" }, { "text": "Which unresolved diagnostic alternatives or patient-specific constraints affect the plan?", "kind": "boundary", "id": "review-and-pathway-selection-q03" } ] } ] }, { "id": "response-and-diagnostic-revision", "name": "Response and diagnostic revision", "description": "Define how follow-up informs activity, causal attribution and longer-term ovarian assessment.", "findings": [ { "id": "reassessment-targets", "name": "Reassessment targets", "description": "Record planned review timing and separate response measures for inflammation, associated collections and ovarian function.", "questions": [ { "text": "Which observations will be reassessed, at what interval, and under whose clinical plan?", "kind": "action", "id": "reassessment-targets-q01" }, { "text": "What lack of improvement or new evidence would prompt reconsideration of localisation, cause or complications?", "kind": "action", "id": "reassessment-targets-q02" }, { "text": "What evidence supports declaring inflammation resolved while retaining any ongoing ovarian functional consequence?", "kind": "boundary", "id": "reassessment-targets-q03" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "This is a recall-based description; no sources were consulted.", "Verify current coding editions and any SNOMED CT or ICD-11 identifiers before assigning them.", "Diagnostic evidence and prevalence should distinguish isolated oophoritis from broader pelvic inflammatory disease; no universal numerical diagnostic threshold is asserted here." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-kinds", "name": "Kinds and varieties", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Infectious oophoritis", "Autoimmune oophoritis", "Acute oophoritis", "Chronic oophoritis" ], "questions": [ { "id": "evidence-kinds-q01", "text": "Which of these kinds and varieties hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "WHO ICD-10", "value_or_pattern": "N70", "note": "The category covers salpingitis and oophoritis together; it does not uniquely identify isolated ovarian inflammation. Subcode selection depends on documented course and the applicable coding edition." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-standards-and-regulation", "name": "Standards and regulation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "World Health Organization International Classification of Diseases, Tenth Revision (ICD-10): classification under salpingitis and oophoritis." ], "questions": [ { "id": "evidence-standards-and-regulation-q01", "text": "Which of these standards and regulation hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Describing ovarian involvement in pelvic inflammatory disease.", "Reporting ovarian inflammation identified on histopathological examination.", "Investigating autoimmune causes of primary ovarian insufficiency." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Infectious inflammation may be complicated by a tubo-ovarian abscess.", "Autoimmune injury may cause follicular loss and primary ovarian insufficiency.", "Associated tubal inflammation can impair fertility; its consequences should not automatically be attributed to isolated ovarian inflammation.", "Pelvic pain or ovarian enlargement alone can be mistaken for evidence of oophoritis." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-regional-variation", "name": "Regional variation", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "National modifications of ICD-10 can differ in coding detail; the jurisdiction and edition should accompany a recorded code." ], "questions": [ { "id": "evidence-regional-variation-q01", "text": "Which of these regional variation hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "Salpingitis", "difference": "Inflammation involves the fallopian tube rather than ovarian tissue; both may coexist." }, { "name": "Pelvic inflammatory disease", "difference": "A broader infectious inflammatory syndrome of the upper female genital tract that may include ovarian involvement." }, { "name": "Tubo-ovarian abscess", "difference": "A localized collection of pus involving the tube and ovary, rather than ovarian inflammation without a defined abscess." }, { "name": "Primary ovarian insufficiency", "difference": "Loss or impairment of ovarian function before age 40; oophoritis is one possible cause, not a requirement." }, { "name": "Ovarian torsion", "difference": "Twisting of the ovarian supporting structures compromises blood flow; this is distinct from primary infectious or autoimmune inflammation." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of oophoritis this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Which current ICD-10, national ICD modifications, ICD-11 and SNOMED CT concepts cover oophoritis, and how do they distinguish isolated ovarian inflammation from combined salpingitis and oophoritis?", "Are there validated diagnostic criteria specifically for isolated oophoritis, and which issuing bodies distinguish clinical suspicion, imaging support and pathological confirmation?", "What diagnostic performance and recommended clinical roles do available autoimmune investigations have, and when can autoimmune oophoritis be attributed without ovarian tissue?", "What prevalence or incidence estimates exist by cause, age, reproductive stage, geography and study year, and do they separate oophoritis from broader PID?", "Which longitudinal evidence establishes recurrence, ovarian functional recovery and fertility outcomes by aetiology, independently of accompanying tubal disease?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 18, "questions": 36 } }