{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-13T06:18:08Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude", "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T10:00:00Z", "ingestedAt": "2026-10-06T07:10:43+00:00", "fields": [ "agent_conduct", "ethics", "owners" ] }, "gate": { "passed": true, "version": "1.0", "at": "2026-10-06T19:51:58+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q3053951", "registryId": "vr.tr.viral-encephalitis", "name": "viral encephalitis", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "XCT.QLT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q3053951/", "model": { "registry_id": "vr.tr.viral-encephalitis", "name": "viral encephalitis", "purpose": "Let an agent explain viral encephalitis and its causes in neutral clinical terms, relay diagnosis, treatment and prevention from neurology and public health sources, describe arboviral and other forms, and route anyone with symptoms to emergency care.", "definition": "Inflammation of the brain caused by viral infection, presenting with fever, headache, altered consciousness, seizures and focal neurological signs, caused by herpes simplex, the most common sporadic cause, varicella-zoster and Epstein-Barr viruses, mosquito-borne arboviruses such as Japanese, West Nile, Western and Venezuelan equine and Jamestown Canyon and Inkoo viruses, rabies, enteroviruses and measles; viral encephalitis is a medical emergency diagnosed by lumbar puncture, imaging and PCR and treated with antivirals where available and supportive care.", "what_it_is_for": "Not applicable; a disease.", "affordances": [ "explain causes", "relay diagnosis and treatment", "describe prevention", "route emergencies" ], "distinguishing_features": [ "Brain parenchyma inflammation", "Viral cause", "Emergency", "Arboviral seasonality" ], "appearance": "Not a visible object; fever with confusion or seizures.", "visual_identification": [ "Viral inflammation of the brain", "Herpes simplex, varicella-zoster, Epstein-Barr, Japanese, West Nile, Western and Venezuelan equine, Jamestown Canyon and Inkoo encephalitis", "Meningitis inflames the membranes; autoimmune encephalitis is not infectious; bacterial encephalitis has other causes" ], "physical_properties": [ { "quantity": "incidence", "typical_range": "about 5-10", "unit": "per 100000 per year", "note": "estimates" }, { "quantity": "most common sporadic cause", "typical_range": "herpes simplex virus", "unit": "note", "note": "" }, { "quantity": "key treatment", "typical_range": "aciclovir for herpes", "unit": "note", "note": "started urgently" } ], "families_and_kinds": [ "herpesvirus encephalitis including herpes simplex, varicella-zoster and Epstein-Barr", "arboviral encephalitis including Japanese, West Nile, tick-borne, Western and Venezuelan equine, Jamestown Canyon and Inkoo", "rabies encephalitis", "enterovirus and measles encephalitis", "post-infectious encephalitis" ], "related_models": [ { "relation": "is a kind of", "target": "infectious encephalitis", "why": "in registry terms" }, { "relation": "is a kind of", "target": "central nervous system viral disease", "why": "in registry terms" }, { "relation": "is caused by", "target": "herpes simplex virus", "why": "most commonly in sporadic cases" }, { "relation": "is prevented by", "target": "vaccine", "why": "for Japanese encephalitis, tick-borne and rabies" } ], "identifiers": [ { "scheme": "ICD-11", "value_or_pattern": "1C8Z and 1D0", "note": "viral encephalitis codes" }, { "scheme": "MeSH", "value_or_pattern": "D018792", "note": "encephalitis, viral" } ], "standards_and_regulation": [ "Neurology and infectious disease guidelines on encephalitis", "Vaccination recommendations for travellers and endemic areas", "Notifiable disease reporting for arboviral encephalitis" ], "failure_modes_and_hazards": [ "Delay in treatment worsening outcomes", "Agents giving personal medical advice", "Confusing encephalitis with meningitis" ], "in_scope": [], "out_of_scope": [], "characteristics": [], "agent_conduct": { "may": [ "Describe viral encephalitis, its causes and signs from medical sources.", "Advise that fever with confusion or seizures needs emergency care." ], "must_not": [ "Give personal medical advice or diagnose encephalitis in a person.", "Suggest waiting or home care for suspected encephalitis.", "Confuse encephalitis with meningitis in guidance." ], "requires_human": [ "Any treatment decision, which belongs to clinicians." ] }, "ethics": { "considerations": [ "Delayed treatment can cause death or lasting brain injury.", "Survivors often face disability and need support." ], "affected_parties": [ "Patients", "Families and carers", "Survivors" ] }, "owners": { "steward": "The patient owns their health data; clinicians and public health authorities hold records.", "master_systems": [ "Notifiable disease surveillance systems" ] } }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q3053951: viral encephalitis", "url": "https://www.wikidata.org/wiki/Q3053951", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Viral encephalitis", "url": "https://en.wikipedia.org/wiki/Viral_encephalitis", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "help", "name": "Help", "description": "Emergency first.", "rationale": "Safety.", "layers": [ { "id": "emergency", "name": "Emergency", "description": "Emergency.", "findings": [ { "id": "emergency-finding", "name": "Emergency", "description": "Emergency.", "questions": [ { "text": "Why do fever with confusion, drowsiness, seizures or new neurological signs need emergency services immediately?", "kind": "action" }, { "text": "Is the user describing these symptoms now, which means calling emergency services?", "kind": "boundary" } ] } ] }, { "id": "exposure", "name": "Exposure", "description": "Exposure.", "findings": [ { "id": "exposure-finding", "name": "Exposure", "description": "Exposure.", "questions": [ { "text": "Why do animal bites or travel to endemic areas with fever need prompt medical assessment?", "kind": "provenance" }, { "text": "Is the user asking about their own exposure, which needs a clinician?", "kind": "boundary" } ] } ] } ] }, { "id": "understand", "name": "Understand", "description": "The disease.", "rationale": "Clinical.", "layers": [ { "id": "causes", "name": "Causes", "description": "Causes.", "findings": [ { "id": "causes-finding", "name": "Causes", "description": "Causes.", "questions": [ { "text": "Which viruses cause encephalitis, from herpesviruses to arboviruses such as Western and Venezuelan equine, Jamestown Canyon and Inkoo, and rabies?", "kind": "definition" }, { "text": "Is the question about viral encephalitis, meningitis or autoimmune encephalitis?", "kind": "boundary" } ] } ] }, { "id": "mechanism", "name": "Mechanism", "description": "Mechanism.", "findings": [ { "id": "mechanism-finding", "name": "Mechanism", "description": "Mechanism.", "questions": [ { "text": "How do viruses reach and damage the brain, and how do symptoms arise?", "kind": "definition" }, { "text": "Which entry fits the specific virus?", "kind": "action" } ] } ] } ] }, { "id": "care", "name": "Care", "description": "Diagnosis and treatment.", "rationale": "Clinical.", "layers": [ { "id": "diagnosis", "name": "Diagnosis", "description": "Diagnosis.", "findings": [ { "id": "diagnosis-finding", "name": "Diagnosis", "description": "Diagnosis.", "questions": [ { "text": "How is viral encephalitis diagnosed by lumbar puncture, PCR, imaging and EEG?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "treatment", "name": "Treatment", "description": "Treatment and outcomes.", "findings": [ { "id": "treatment-finding", "name": "Treatment", "description": "Treatment.", "questions": [ { "text": "How is encephalitis treated, and what are outcomes and rehabilitation needs, in general terms?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Prevention and research.", "rationale": "Context.", "layers": [ { "id": "prevention", "name": "Prevention", "description": "Prevention.", "findings": [ { "id": "prevention-finding", "name": "Prevention", "description": "Prevention.", "questions": [ { "text": "How do vaccines, mosquito and tick control and rabies prophylaxis prevent encephalitis?", "kind": "provenance" }, { "text": "Which entry fits Japanese encephalitis vaccine?", "kind": "action" } ] } ] }, { "id": "research", "name": "Research", "description": "Research.", "findings": [ { "id": "research-finding", "name": "Research", "description": "Research.", "questions": [ { "text": "What research addresses diagnosis, antivirals and long-term effects, with findings attributed?", "kind": "provenance" }, { "text": "Which entry fits neuroinfectious disease?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should herpes simplex encephalitis and Japanese encephalitis be separate primary entries?", "How should clinical guidelines be linked?", "The registry entry has merged aliases naming specific viral causes; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }