{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-13T07:14:03Z", "providers": [ "Claude" ], "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify", "pass": 2, "wave": 3, "engine": "claude", "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T10:00:00Z", "ingestedAt": "2026-10-06T07:10:30+00:00", "fields": [ "agent_conduct", "ethics", "owners" ] }, "revisions": [ { "at": "2026-10-06T22:47:51+00:00", "engine": "codex", "fields": [ "definition", "visual_identification" ], "answering_review": "13a481873a3d68df18e4d5ba09def0c196d2411f9773238826f60b2d6105195b" } ], "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T10:10:29+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q306156", "registryId": "vr.tr.enone", "name": "enone", "version": "0.2.0-wave.3", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q306156/", "model": { "registry_id": "vr.tr.enone", "name": "enone", "purpose": "Let an agent explain enones and their reactivity, relay chemistry and examples from organic chemistry references, describe their role in steroids and natural products, and distinguish enones from simple ketones, enals, enols and unconjugated unsaturated ketones.", "definition": "An organic compound containing a ketone group conjugated with a carbon-carbon double bond, the alpha,beta-unsaturated ketone motif, found in natural products, steroids such as 3-oxo-delta-4 and 3-oxo-delta-1 steroids including testosterone and progesterone, cyclohexenones, and in synthetic intermediates; enones are Michael acceptors and undergo characteristic conjugate additions, cycloadditions and photochemical reactions.", "what_it_is_for": "Not applicable; a class of compounds.", "affordances": [ "explain the class", "relay reactivity", "describe examples", "distinguish related classes" ], "distinguishing_features": [ "Conjugation", "Michael acceptor", "Steroid motif", "Synthetic building block" ], "appearance": "Not a visible object; molecules.", "visual_identification": [ "An enone contains a ketone conjugated with a C=C double bond.", "Examples include the 3-oxo steroids, cyclohexenones and hydroxy-oxo-heptadienoic acids named in the aliases.", "Enals are aldehydes, enols have OH on a double bond, and simple ketones lack conjugation." ], "physical_properties": [ { "quantity": "motif", "typical_range": "C=C-C=O", "unit": "structure", "note": "" }, { "quantity": "simplest", "typical_range": "methyl vinyl ketone", "unit": "note", "note": "" }, { "quantity": "reactivity", "typical_range": "Michael addition, Diels-Alder, photochemistry", "unit": "list", "note": "" } ], "families_and_kinds": [ "acyclic enones such as methyl vinyl ketone", "cyclic enones such as cyclohexenones and cyclopentenones", "steroidal enones such as 3-oxo-delta-4 steroids", "furanones and butenolides", "natural product enones and Michael acceptors", "dienones and cross-conjugated systems" ], "related_models": [ { "relation": "is a kind of", "target": "alpha,beta-unsaturated ketone", "why": "in registry terms" }, { "relation": "is a kind of", "target": "olefinic compound", "why": "in registry terms" }, { "relation": "undergoes", "target": "Michael reaction", "why": "as an acceptor" }, { "relation": "is contrasted with", "target": "enal", "why": "the aldehyde analogue" } ], "identifiers": [ { "scheme": "ChEBI", "value_or_pattern": "CHEBI:51689", "note": "enone" } ], "standards_and_regulation": [ "IUPAC nomenclature", "Chemical safety rules for reactive Michael acceptors" ], "failure_modes_and_hazards": [ "Confusing enones with enols or enals", "Registry aliases naming obscure specific compounds", "Reactivity hazards of some enones" ], "in_scope": [], "out_of_scope": [], "characteristics": [], "agent_conduct": { "may": [ "Explain the enone motif and how it differs from enols and enals.", "Name natural products and steroids that contain enones." ], "must_not": [ "Give synthesis procedures for regulated steroids or other controlled enone compounds.", "Present a reactive enone as safe to handle without regard to its hazard data.", "Confuse an obscure systematic compound name with a familiar one.", "Advise anyone on using steroid hormones without a prescription." ], "requires_human": [ "Laboratory work with reactive or controlled enone compounds." ] }, "ethics": { "considerations": [ "Some enones are irritants and sensitisers that harm workers.", "Steroid enones are misused for doping and without medical oversight." ], "affected_parties": [ "Laboratory workers", "Athletes", "Students" ] }, "owners": { "steward": "Nobody owns the class; chemical nomenclature bodies maintain its naming.", "master_systems": [ "Chemical substance databases" ] } }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q306156: enone", "url": "https://www.wikidata.org/wiki/Q306156", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Enone", "url": "https://en.wikipedia.org/wiki/Enone", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "understand", "name": "Understand", "description": "What an enone is.", "rationale": "Science.", "layers": [ { "id": "definition", "name": "Definition", "description": "Definition.", "findings": [ { "id": "definition-finding", "name": "Definition", "description": "Definition.", "questions": [ { "text": "What is an enone, and how does it differ from enals, enols and simple ketones?", "kind": "definition" }, { "text": "Is the question about the class, a specific compound or a reaction?", "kind": "boundary" } ] } ] }, { "id": "examples", "name": "Examples", "description": "Examples.", "findings": [ { "id": "examples-finding", "name": "Examples", "description": "Examples.", "questions": [ { "text": "What are cyclohexenones, furanones, 3-oxo steroids and the specific compounds named in the registry?", "kind": "definition" }, { "text": "Which entry fits the specific compound?", "kind": "action" } ] } ] } ] }, { "id": "chemistry", "name": "Chemistry", "description": "Reactivity.", "rationale": "Science.", "layers": [ { "id": "reactions", "name": "Reactions", "description": "Reactions.", "findings": [ { "id": "reactions-finding", "name": "Reactions", "description": "Reactions.", "questions": [ { "text": "How do enones undergo Michael additions, Diels-Alder reactions, reductions and photochemistry?", "kind": "provenance" }, { "text": "Which references are standard?", "kind": "provenance" } ] } ] }, { "id": "synthesis", "name": "Synthesis", "description": "Synthesis.", "findings": [ { "id": "synthesis-finding", "name": "Synthesis", "description": "Synthesis.", "questions": [ { "text": "How are enones prepared, for example by aldol condensation and Robinson annulation?", "kind": "provenance" }, { "text": "Which sources are cited?", "kind": "provenance" } ] } ] } ] }, { "id": "biology", "name": "Biology", "description": "Biology and medicine.", "rationale": "Science.", "layers": [ { "id": "steroids", "name": "Steroids", "description": "Steroid enones.", "findings": [ { "id": "steroids-finding", "name": "Steroids", "description": "Steroids.", "questions": [ { "text": "What role do 3-oxo-delta-4 and delta-1 enones play in steroid hormones and drugs?", "kind": "provenance" }, { "text": "Which entry fits steroid hormone?", "kind": "action" } ] } ] }, { "id": "natural", "name": "Natural", "description": "Natural products.", "findings": [ { "id": "natural-finding", "name": "Natural", "description": "Natural.", "questions": [ { "text": "What natural enones are bioactive, and why are Michael acceptors important in drug design?", "kind": "provenance" }, { "text": "Which entry fits covalent inhibitor?", "kind": "action" } ] } ] } ] }, { "id": "context", "name": "Context", "description": "Nomenclature and safety.", "rationale": "Context.", "layers": [ { "id": "nomenclature", "name": "Nomenclature", "description": "Naming.", "findings": [ { "id": "nomenclature-finding", "name": "Nomenclature", "description": "Nomenclature.", "questions": [ { "text": "How are enones named systematically?", "kind": "provenance" }, { "text": "Which entry fits IUPAC nomenclature?", "kind": "action" } ] } ] }, { "id": "safety", "name": "Safety", "description": "Safety.", "findings": [ { "id": "safety-finding", "name": "Safety", "description": "Safety.", "questions": [ { "text": "What safety considerations apply to reactive enones, in general terms?", "kind": "provenance" }, { "text": "Which entry fits laboratory safety?", "kind": "action" } ] } ] } ] } ] }, "openQuestions": [ "Should cyclohexenone and 3-oxo-delta-4 steroid be separate entries?", "How should chemistry references be linked?", "The registry entry has merged aliases naming specific compounds; should they be split off?" ], "statistics": { "bundles": 4, "layers": 8, "findings": 8, "questions": 16 } }