{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-14T02:02:46Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 4,
    "engine": "claude",
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-06T11:00:00Z",
      "ingestedAt": "2026-10-06T07:44:09+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "owners"
      ]
    },
    "revisions": [
      {
        "at": "2026-10-06T22:48:41+00:00",
        "engine": "codex",
        "fields": [
          "definition",
          "visual_identification"
        ],
        "answering_review": "f5066848ff5613305297c802a2c5035756dc3904af44cced1afa368416b78945"
      }
    ],
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-07T10:10:30+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q3312266",
    "registryId": "vr.tr.loose-connective-tissue",
    "name": "loose connective tissue",
    "version": "0.2.0-wave.4",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "PHY.LIV"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q3312266/",
  "model": {
    "registry_id": "vr.tr.loose-connective-tissue",
    "name": "loose connective tissue",
    "purpose": "Let an agent explain loose connective tissue, relay types, cells, functions and locations from histology sources, describe the named forms, and distinguish loose from dense connective tissue, specialised connective tissues such as bone and blood, and epithelium.",
    "definition": "A category of connective tissue with abundant ground substance and loosely arranged fibres and cells, filling spaces, supporting organs, surrounding vessels and nerves and hosting immune cells, including areolar tissue, adipose tissue and reticular tissue; forms and locations the registry aliases name include reticular tissue, which forms the framework of lymphoid organs and bone marrow stroma, mucoid or mucous connective tissue as in the umbilical cord s Wharton jelly, pigmented connective tissue, and organ-specific loose tissue such as ovarian medulla stroma. It contrasts with dense connective tissue, which has tightly packed fibres and forms the thymus capsule.",
    "what_it_is_for": "Support, cushioning and immune defence between tissues.",
    "affordances": [
      "explain types and cells",
      "relay functions",
      "describe named forms",
      "distinguish related tissues"
    ],
    "distinguishing_features": [
      "Loosely arranged fibres",
      "Abundant ground substance",
      "Immune cells present",
      "Fills spaces"
    ],
    "appearance": "Under the microscope, sparse fibres and scattered cells in abundant ground substance.",
    "visual_identification": [
      "Loose connective tissue has loosely arranged fibres.",
      "Examples include stroma of the ovarian medulla, mucoid tissue, pigmented connective tissue, reticular tissue and stroma of bone marrow.",
      "Dense connective tissue has packed fibres and forms the thymus capsule, bone and blood are specialised connective tissues, and epithelium lines surfaces."
    ],
    "physical_properties": [
      {
        "quantity": "main types",
        "typical_range": "areolar, adipose, reticular",
        "unit": "list",
        "note": ""
      },
      {
        "quantity": "ground substance",
        "typical_range": "gel of glycosaminoglycans",
        "unit": "note",
        "note": ""
      },
      {
        "quantity": "registry parents",
        "typical_range": "connective tissue, irregular connective tissue",
        "unit": "note",
        "note": ""
      }
    ],
    "families_and_kinds": [
      "areolar tissue",
      "adipose tissue",
      "reticular tissue",
      "mucoid connective tissue"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "connective tissue",
        "why": "in registry terms"
      },
      {
        "relation": "includes",
        "target": "areolar tissue",
        "why": ""
      },
      {
        "relation": "is contrasted with",
        "target": "dense connective tissue",
        "why": ""
      },
      {
        "relation": "is contrasted with",
        "target": "epithelium",
        "why": ""
      }
    ],
    "identifiers": [],
    "standards_and_regulation": [
      "Histology terminology standards"
    ],
    "failure_modes_and_hazards": [
      "Confusing loose and dense connective tissue",
      "Treating stroma of specific organs as separate tissue types",
      "Oversimplified histology"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": [],
    "agent_conduct": {
      "may": [
        "Describe the types of loose connective tissue and where they are found.",
        "Distinguish loose from dense connective tissue in teaching material."
      ],
      "must_not": [
        "Treat the stroma of specific organs as separate tissue types without saying so.",
        "Interpret a person's biopsy or histology report.",
        "Present oversimplified histology as clinical fact."
      ],
      "requires_human": [
        "Using tissue descriptions to inform a diagnosis."
      ]
    },
    "ethics": {
      "considerations": [
        "Errors in teaching material carry into clinical practice.",
        "Tissue samples come from people whose consent and privacy matter."
      ],
      "affected_parties": [
        "Students",
        "Patients",
        "Tissue donors"
      ]
    },
    "owners": {
      "steward": "Nobody owns the concept; anatomists and pathologists maintain the science.",
      "master_systems": []
    }
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q3312266: loose connective tissue",
      "url": "https://www.wikidata.org/wiki/Q3312266",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Loose connective tissue",
      "url": "https://en.wikipedia.org/wiki/Loose_connective_tissue",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "understand",
        "name": "Understand",
        "description": "What loose connective tissue is.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "definition",
            "name": "Definition",
            "description": "Definition.",
            "findings": [
              {
                "id": "definition-finding",
                "name": "Definition",
                "description": "Definition.",
                "questions": [
                  {
                    "text": "What is loose connective tissue, and how does it differ from dense connective tissue, bone and blood and epithelium?",
                    "kind": "definition"
                  },
                  {
                    "text": "Is the question about histology, anatomy or a specific organ s stroma?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "forms",
            "name": "Forms",
            "description": "Named forms.",
            "findings": [
              {
                "id": "forms-finding",
                "name": "Forms",
                "description": "Forms.",
                "questions": [
                  {
                    "text": "What are areolar, reticular, mucoid and pigmented connective tissue and organ-specific stroma?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which entry fits the specific form?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "histology",
        "name": "Histology",
        "description": "Histology.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "cells",
            "name": "Cells",
            "description": "Cells.",
            "findings": [
              {
                "id": "cells-finding",
                "name": "Cells",
                "description": "Cells.",
                "questions": [
                  {
                    "text": "Which cells such as fibroblasts and immune cells populate loose tissue?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which references are standard?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "matrix",
            "name": "Matrix",
            "description": "Extracellular matrix.",
            "findings": [
              {
                "id": "matrix-finding",
                "name": "Matrix",
                "description": "Matrix.",
                "questions": [
                  {
                    "text": "What fibres and ground substance make up the matrix?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which sources are cited?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "functions",
        "name": "Functions",
        "description": "Functions.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "support",
            "name": "Support",
            "description": "Support and cushioning.",
            "findings": [
              {
                "id": "support-finding",
                "name": "Support",
                "description": "Support.",
                "questions": [
                  {
                    "text": "How does loose tissue support and cushion organs?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits areolar tissue?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "immune",
            "name": "Immune",
            "description": "Immune role.",
            "findings": [
              {
                "id": "immune-finding",
                "name": "Immune",
                "description": "Immune.",
                "questions": [
                  {
                    "text": "How does loose connective tissue host immune defence?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Is the information accurate?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "context",
        "name": "Context",
        "description": "Specialised.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "reticular",
            "name": "Reticular",
            "description": "Reticular tissue.",
            "findings": [
              {
                "id": "reticular-finding",
                "name": "Reticular",
                "description": "Reticular.",
                "questions": [
                  {
                    "text": "How does reticular tissue frame lymphoid organs and bone marrow?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits reticular fiber?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "mucoid",
            "name": "Mucoid",
            "description": "Wharton jelly.",
            "findings": [
              {
                "id": "mucoid-finding",
                "name": "Mucoid",
                "description": "Mucoid.",
                "questions": [
                  {
                    "text": "What is mucoid connective tissue such as Wharton jelly?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Is the presentation neutral and attributed?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should reticular and mucoid tissue be separate entries?",
    "Should organ-specific stroma be treated as instances?",
    "How should histology atlases be linked?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}