{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-12T10:32:31Z",
    "providers": [
      "Codex"
    ],
    "breadth": "recalled by Codex without web access - no source was read",
    "missingProviders": [],
    "pass": 2,
    "cost": {
      "grok": {
        "seconds": 17.2,
        "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a0952b-e0e2-7b31-bff7-56bda93a9d48\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: interventricular foramina\nSense to describe: (none recorded)\nDomain code: PHY.OBJ\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Batch",
        "usd": 0.0,
        "recall": true
      },
      "codex": {
        "seconds": 75.8,
        "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a0952b-e0e7-7fc1-9daa-f4f55d8592bc\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: interventricular foramina\nRegistry id: vr.tr.interventricular-foramina\nPlane / domain: PHY / PHY.OBJ\nRegistry definition: (none recorded)\nNames folde"
      }
    },
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-06T12:00:00Z",
      "ingestedAt": "2026-10-06T08:55:40+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "failure_modes_and_hazards",
        "owners",
        "standards_and_regulation",
        "visual_identification"
      ]
    },
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-07T10:10:30+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q3540833",
    "registryId": "vr.tr.interventricular-foramina",
    "name": "interventricular foramina",
    "version": "0.1.0-research.1",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "PHY.OBJ"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q3540833/",
  "model": {
    "registry_id": "vr.tr.interventricular-foramina",
    "name": "interventricular foramina",
    "purpose": "Enable an agent to identify the interventricular foramina, record their anatomy and evidence of patency, and support review of abnormalities affecting communication between the lateral and third ventricles.",
    "definition": "The interventricular foramina, also called the foramina of Monro, are paired openings in the brain that connect each lateral ventricle with the third ventricle and permit cerebrospinal fluid to pass between them.",
    "scope_statement": "This model owns vr.tr.interventricular-foramina as the paired anatomical passages connecting the lateral ventricles with the third ventricle, with observations recorded separately for each side; human anatomy is the initial reference context, and other species require explicit qualification.",
    "in_scope": [
      "Identity of the paired foramina and side-specific observations",
      "Connections between each lateral ventricle and the third ventricle",
      "Local boundaries, neighbouring structures and anatomical variation",
      "Foraminal geometry and evidence of patency or obstruction",
      "Imaging visibility, measurement uncertainty and changes after intervention"
    ],
    "out_of_scope": [
      "The ventricular system as a whole",
      "Cerebrospinal fluid production and absorption mechanisms",
      "Hydrocephalus diagnosis and treatment as a complete clinical model",
      "Colloid cysts, tumours and other obstructing lesions as independent entities",
      "Neurosurgical procedures, instruments and operative protocols",
      "Cardiac interventricular openings and septal defects"
    ],
    "distinguishing_features": [
      "Each passage connects a lateral ventricle with the third ventricle; confirm these endpoints before assigning the identity. Anatomical reference: [Three-dimensional anatomy of the central core](https://d1xe7tfg0uwul9.cloudfront.net/cbc-portal/wp-content/uploads/2013/07/02022011-JNS1.pdf).",
      "The cerebral aqueduct connects the third and fourth ventricles, whereas these foramina occupy the lateral-to-third ventricular junction.",
      "The fourth ventricular apertures communicate with the subarachnoid space, which is not the defining connection here.",
      "A septal fenestration connects the lateral ventricles across the septum pellucidum and must not be labelled an interventricular foramen of Monro.",
      "The local relationship to the fornix and thalamus helps distinguish the foramina from an adjacent cavity or lesion; displacement requires checking ventricular continuity rather than relying on position alone."
    ],
    "characteristics": [
      {
        "name": "Observation laterality",
        "kind": "category",
        "unit_or_values": "left | right | bilateral | indeterminate",
        "why_it_matters": "Preserves differences between the two passages without creating separate registry concepts."
      },
      {
        "name": "Anatomical context",
        "kind": "category",
        "unit_or_values": "species, developmental stage and native or surgically altered anatomy",
        "why_it_matters": "Prevents unqualified transfer of anatomical expectations between populations or altered ventricular configurations."
      },
      {
        "name": "Ventricular endpoints",
        "kind": "relation",
        "unit_or_values": "ipsilateral lateral ventricle and third ventricle, with evidence for each connection",
        "why_it_matters": "Establishes identity through anatomical continuity."
      },
      {
        "name": "Minimum visible lumen dimensions",
        "kind": "measurement",
        "unit_or_values": "mm; specify side, plane, sequence, boundary convention and uncertainty",
        "why_it_matters": "Supports reproducible descriptions of narrowing without assuming a universal normal diameter."
      },
      {
        "name": "Visible lumen area",
        "kind": "measurement",
        "unit_or_values": "mm²; specify section orientation and segmentation method",
        "why_it_matters": "Describes irregular openings when a single diameter is inadequate."
      },
      {
        "name": "Patency assessment",
        "kind": "state",
        "unit_or_values": "supported patent | suspected partial obstruction | supported complete obstruction | indeterminate",
        "why_it_matters": "Separates interpreted passage status from visibility or size alone."
      },
      {
        "name": "CSF transit evidence",
        "kind": "category",
        "unit_or_values": "directly demonstrated | indirectly supported | not demonstrated | not assessed; include method",
        "why_it_matters": "Prevents an anatomical opening or absent flow signal from being treated as conclusive functional evidence."
      },
      {
        "name": "Local obstructing or displacing entity",
        "kind": "relation",
        "unit_or_values": "linked lesion, membrane, adhesion or other finding; suspected or confirmed relationship",
        "why_it_matters": "Connects the foraminal abnormality to its proposed cause while keeping the cause in its own model."
      },
      {
        "name": "Foraminal assessability",
        "kind": "state",
        "unit_or_values": "adequately visualized | partially visualized | not resolved | obscured by artefact",
        "why_it_matters": "Distinguishes an unobservable passage from an absent or occluded passage."
      }
    ],
    "affordances": [
      "Identify and annotate each foramen in a ventricular image or anatomical specimen.",
      "Compare left and right lumen geometry using a documented measurement convention.",
      "Associate suspected obstruction with a local lesion and the observed ventricular enlargement pattern.",
      "Track foraminal appearance and patency evidence across examinations or interventions.",
      "Flag uncertain identity, inadequate visualization or conflicting structural and flow evidence for expert review."
    ],
    "agent_conduct": {
      "may": [
        "Describe the interventricular foramina and their role in cerebrospinal fluid flow, citing anatomical sources.",
        "Explain that blockage here can cause raised pressure and needs urgent medical care."
      ],
      "must_not": [
        "Diagnose hydrocephalus or a brain lesion in a person from images or symptoms.",
        "Share a person's brain imaging or records without consent.",
        "Delay advice to seek emergency care when symptoms of raised brain pressure are described.",
        "Present surgical options as decided for a person."
      ],
      "requires_human": [
        "Any clinical decision about a person's brain imaging.",
        "Publishing images from a patient's records."
      ]
    },
    "ethics": {
      "considerations": [
        "Brain conditions are frightening and sensitive, so information must be accurate and careful.",
        "Delayed care for blocked fluid flow can cause lasting harm."
      ],
      "affected_parties": [
        "Patients",
        "Families",
        "Clinicians"
      ]
    },
    "owners": {
      "steward": "The person in whose body they lie; clinicians hold the records of findings.",
      "master_systems": []
    },
    "visual_identification": [
      "Paired small openings between each lateral ventricle and the third ventricle.",
      "Seen on brain imaging or in dissection, not from outside the body."
    ],
    "failure_modes_and_hazards": [
      "Blockage by cysts or tumours causing hydrocephalus.",
      "Misreading of imaging by non-specialists."
    ],
    "standards_and_regulation": [
      "Terminologia Anatomica, Federative International Programme for Anatomical Terminology (FIPAT)."
    ],
    "what_it_is_for": [
      "These paired openings are encountered in neuroanatomy, brain imaging and neurosurgical assessment of the ventricular system.",
      "Their location and openness are assessed when investigating impaired cerebrospinal fluid circulation or enlargement of the lateral ventricles."
    ]
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q3540833: interventricular foramina",
      "url": "https://www.wikidata.org/wiki/Q3540833",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Interventricular foramina (neuroanatomy)",
      "url": "https://en.wikipedia.org/wiki/Interventricular_foramina_%28neuroanatomy%29",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "ventricular-identity",
        "name": "Ventricular identity",
        "description": "Establish which passages are represented and how side-specific observations belong to the registered pair.",
        "rationale": "The plural entry must retain paired anatomy while avoiding confusion with other ventricular communications.",
        "layers": [
          {
            "id": "paired-foramina",
            "name": "Paired foramina",
            "description": "Bind observations to the registered anatomical kind and the appropriate side.",
            "findings": [
              {
                "id": "pair-and-side",
                "name": "Pair and side",
                "description": "Record whether an observation concerns one foramen or the pair, retaining the single registry identity.",
                "questions": [
                  {
                    "text": "Does this observation describe the left foramen, the right foramen or both?",
                    "kind": "definition",
                    "id": "pair-and-side-q01"
                  },
                  {
                    "text": "What image orientation or specimen label establishes the assigned side?",
                    "kind": "provenance",
                    "id": "pair-and-side-q02"
                  }
                ]
              }
            ]
          },
          {
            "id": "ventricular-continuity",
            "name": "Ventricular continuity",
            "description": "Identify each passage by the spaces it connects.",
            "findings": [
              {
                "id": "endpoint-confirmation",
                "name": "Endpoint confirmation",
                "description": "Trace continuity with the ipsilateral lateral ventricle and the third ventricle before accepting a label.",
                "questions": [
                  {
                    "text": "Can both ventricular endpoints be followed through the available images or specimen?",
                    "kind": "boundary",
                    "id": "endpoint-confirmation-q01"
                  },
                  {
                    "text": "Could the apparent opening instead be a septal fenestration, adjacent recess or surgically created communication?",
                    "kind": "definition",
                    "id": "endpoint-confirmation-q02"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "foraminal-anatomy",
        "name": "Foraminal anatomy",
        "description": "Describe the local margins, lumen geometry and relevant variation.",
        "rationale": "The identity and assessment of these small passages depend on their surrounding anatomy and the way their lumen is measured.",
        "layers": [
          {
            "id": "local-landmarks",
            "name": "Local landmarks",
            "description": "Record relationships to the fornix, thalamus, choroid plexus and nearby vessels.",
            "findings": [
              {
                "id": "margin-recognition",
                "name": "Margin recognition",
                "description": "Document visible local landmarks and any distortion; anatomical context is illustrated in [Three-dimensional anatomy of the central core](https://d1xe7tfg0uwul9.cloudfront.net/cbc-portal/wp-content/uploads/2013/07/02022011-JNS1.pdf).",
                "questions": [
                  {
                    "text": "Which foraminal margins can be identified relative to the fornix and thalamus?",
                    "kind": "boundary",
                    "id": "margin-recognition-q01"
                  },
                  {
                    "text": "Do choroid plexus, vessels or displaced tissue obscure the lumen boundary?",
                    "kind": "boundary",
                    "id": "margin-recognition-q02"
                  }
                ]
              }
            ]
          },
          {
            "id": "lumen-geometry",
            "name": "Lumen geometry",
            "description": "Capture dimensions and shape using explicit anatomical and acquisition conventions.",
            "findings": [
              {
                "id": "dimension-and-asymmetry",
                "name": "Dimension and asymmetry",
                "description": "Measure each assessable lumen independently and retain the method needed to interpret asymmetry.",
                "questions": [
                  {
                    "text": "What are the minimum visible dimensions or cross-sectional area, and in which plane were they measured?",
                    "kind": "measurement",
                    "id": "dimension-and-asymmetry-q01"
                  },
                  {
                    "text": "Does the apparent left-right difference persist when both sides are assessed with comparable orientation and resolution?",
                    "kind": "measurement",
                    "id": "dimension-and-asymmetry-q02"
                  },
                  {
                    "text": "What species, age or altered-anatomy context limits comparison with a reference population?",
                    "kind": "boundary",
                    "id": "dimension-and-asymmetry-q03"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "patency-and-csf-transit",
        "name": "Patency and CSF transit",
        "description": "Separate structural openness from evidence that cerebrospinal fluid traverses each passage.",
        "rationale": "A visible lumen, an unresolved lumen and a flow observation support different conclusions about foraminal function.",
        "layers": [
          {
            "id": "structural-patency",
            "name": "Structural patency",
            "description": "Assess continuity and material occupying or narrowing the passage.",
            "findings": [
              {
                "id": "lumen-continuity",
                "name": "Lumen continuity",
                "description": "Express patency as an evidence-qualified assessment for each side.",
                "questions": [
                  {
                    "text": "Is an uninterrupted lumen demonstrated, or is narrowing or occluding material visible?",
                    "kind": "boundary",
                    "id": "lumen-continuity-q01"
                  },
                  {
                    "text": "What evidence distinguishes true occlusion from inadequate spatial resolution or an oblique section?",
                    "kind": "provenance",
                    "id": "lumen-continuity-q02"
                  }
                ]
              }
            ]
          },
          {
            "id": "functional-transit",
            "name": "Functional transit",
            "description": "Record flow evidence with its acquisition conditions and limitations.",
            "findings": [
              {
                "id": "transit-evidence",
                "name": "Transit evidence",
                "description": "Avoid treating structural appearance as proof of adequate CSF transit or absent signal as proof of obstruction.",
                "questions": [
                  {
                    "text": "Was transit through this specific foramen demonstrated directly, inferred indirectly or not assessed?",
                    "kind": "measurement",
                    "id": "transit-evidence-q01"
                  },
                  {
                    "text": "Which acquisition settings and technical limitations affect interpretation of the flow observation?",
                    "kind": "provenance",
                    "id": "transit-evidence-q02"
                  },
                  {
                    "text": "Does disagreement between structural and flow observations require additional assessment?",
                    "kind": "action",
                    "id": "transit-evidence-q03"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "obstruction-and-ventricular-effects",
        "name": "Obstruction and ventricular effects",
        "description": "Relate local abnormalities to their suspected causes and associated ventricular changes.",
        "rationale": "The model must distinguish a foraminal finding from the lesion causing it and from downstream clinical interpretation.",
        "layers": [
          {
            "id": "local-mechanism",
            "name": "Local mechanism",
            "description": "Characterize whether the passage is occupied, compressed, narrowed or displaced.",
            "findings": [
              {
                "id": "cause-and-contact",
                "name": "Cause and contact",
                "description": "Record the proposed obstruction mechanism and link the responsible entity separately; lesion relationships are examined in [A classification of lesions around interventricular foramen and its clinical value](https://pmc.ncbi.nlm.nih.gov/articles/PMC4637789/).",
                "questions": [
                  {
                    "text": "What observed entity occupies, compresses or distorts the foramen, and on which side?",
                    "kind": "boundary",
                    "id": "cause-and-contact-q01"
                  },
                  {
                    "text": "Is the proposed causal relationship directly observed or inferred from proximity?",
                    "kind": "provenance",
                    "id": "cause-and-contact-q02"
                  }
                ]
              }
            ]
          },
          {
            "id": "ventricular-response",
            "name": "Ventricular response",
            "description": "Link local patency assessments to the configuration of connected ventricular compartments.",
            "findings": [
              {
                "id": "compartment-pattern",
                "name": "Compartment pattern",
                "description": "Record associated ventricular changes without deriving a complete hydrocephalus diagnosis from foraminal appearance.",
                "questions": [
                  {
                    "text": "What enlargement or interval change is present in each lateral ventricle and the third ventricle?",
                    "kind": "measurement",
                    "id": "compartment-pattern-q01"
                  },
                  {
                    "text": "Is that pattern consistent with the proposed side and extent of foraminal obstruction?",
                    "kind": "boundary",
                    "id": "compartment-pattern-q02"
                  },
                  {
                    "text": "What conflicting observations require review before attributing the ventricular changes to this foramen?",
                    "kind": "action",
                    "id": "compartment-pattern-q03"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "observation-and-altered-anatomy",
        "name": "Observation and altered anatomy",
        "description": "Preserve evidence quality and distinguish native foraminal anatomy from changes following intervention.",
        "rationale": "Small-lumen observations are sensitive to acquisition method, and an alternative ventricular route does not establish native foraminal patency.",
        "layers": [
          {
            "id": "observation-quality",
            "name": "Observation quality",
            "description": "Attach the acquisition and interpretive evidence necessary to assess a foraminal claim.",
            "findings": [
              {
                "id": "local-assessability",
                "name": "Local assessability",
                "description": "Record whether the specific foramen is resolved and which source supports its annotation.",
                "questions": [
                  {
                    "text": "Which examination, sequence, image location or specimen observation supports the annotation?",
                    "kind": "provenance",
                    "id": "local-assessability-q01"
                  },
                  {
                    "text": "Are resolution, motion and partial-volume effects compatible with the claimed lumen boundary?",
                    "kind": "measurement",
                    "id": "local-assessability-q02"
                  },
                  {
                    "text": "Should the result remain indeterminate because the foramen is not adequately visualized?",
                    "kind": "action",
                    "id": "local-assessability-q03"
                  }
                ]
              }
            ]
          },
          {
            "id": "intervention-and-follow-up",
            "name": "Intervention and follow-up",
            "description": "Track changes to the native passage and related ventricular communications over time.",
            "findings": [
              {
                "id": "native-versus-created-route",
                "name": "Native versus created route",
                "description": "Distinguish a modified native foramen from an alternative communication, and compare follow-up observations under compatible conditions.",
                "questions": [
                  {
                    "text": "Did the documented intervention modify this native foramen or create a separate CSF route?",
                    "kind": "boundary",
                    "id": "native-versus-created-route-q01"
                  },
                  {
                    "text": "What operative record or imaging evidence establishes the altered anatomy?",
                    "kind": "provenance",
                    "id": "native-versus-created-route-q02"
                  },
                  {
                    "text": "Which changes in lumen appearance, transit evidence and ventricular configuration can be supported on follow-up?",
                    "kind": "measurement",
                    "id": "native-versus-created-route-q03"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "evidence-and-external-alignment",
        "name": "Evidence and external alignment",
        "description": "What the world already says about this thing, gathered so the model can be checked against it.",
        "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.",
        "layers": [
          {
            "id": "reported-evidence",
            "name": "Reported evidence",
            "description": "Findings from the breadth pass, kept separate from the structural claims.",
            "findings": [
              {
                "id": "evidence-confidence-notes",
                "name": "Check these first",
                "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                "evidence": [
                  "The intended sense is inferred to be the cerebral foramina of Monro; no sense was recorded.",
                  "No typical dimensions are supplied because size depends on age, anatomy, pathology and measurement method.",
                  "Terminology and anatomical claims are recalled knowledge, not source-verified research."
                ],
                "questions": [
                  {
                    "id": "evidence-confidence-notes-q01",
                    "text": "Which of these check these first hold for the sense of interventricular foramina this model covers, and on what evidence?",
                    "kind": "provenance"
                  }
                ]
              },
              {
                "id": "evidence-identifiers",
                "name": "Identifiers and schemes",
                "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                "evidence": [
                  {
                    "scheme": "Terminologia Anatomica",
                    "value_or_pattern": "Foramen interventriculare",
                    "note": "Latin anatomical term in the singular; the plural is foramina interventricularia."
                  }
                ],
                "questions": [
                  {
                    "id": "evidence-identifiers-q01",
                    "text": "Which of these identifiers and schemes hold for the sense of interventricular foramina this model covers, and on what evidence?",
                    "kind": "provenance"
                  }
                ]
              },
              {
                "id": "evidence-real-world-use",
                "name": "Real-world use",
                "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                "evidence": [
                  "Provide the normal passage for cerebrospinal fluid from the lateral ventricles into the third ventricle.",
                  "Serve as anatomical landmarks in ventricular imaging and endoscopic neurosurgery.",
                  "Are assessed when investigating ventricular enlargement and suspected cerebrospinal fluid obstruction."
                ],
                "questions": [
                  {
                    "id": "evidence-real-world-use-q01",
                    "text": "Which of these real-world use hold for the sense of interventricular foramina this model covers, and on what evidence?",
                    "kind": "provenance"
                  }
                ]
              },
              {
                "id": "evidence-failure-modes-and-hazards",
                "name": "Failure modes and hazards",
                "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                "evidence": [
                  "Obstruction can cause noncommunicating hydrocephalus affecting one or both lateral ventricles.",
                  "Colloid cysts near the roof of the third ventricle can obstruct these openings.",
                  "Tumours, inflammatory adhesions or intraventricular blood can impair their patency.",
                  "Surgical manipulation nearby risks injury to the fornix and associated memory pathways."
                ],
                "questions": [
                  {
                    "id": "evidence-failure-modes-and-hazards-q01",
                    "text": "Which of these failure modes and hazards hold for the sense of interventricular foramina this model covers, and on what evidence?",
                    "kind": "provenance"
                  }
                ]
              },
              {
                "id": "evidence-neighbours",
                "name": "Neighbouring kinds and how to tell them apart",
                "description": "Recalled without web access and unsourced; every item is a lead to verify.",
                "evidence": [
                  {
                    "name": "Lateral ventricles",
                    "difference": "These are paired cerebrospinal fluid cavities; the interventricular foramina are their openings into the third ventricle."
                  },
                  {
                    "name": "Third ventricle",
                    "difference": "This is the midline ventricular cavity receiving the two foramina, rather than an opening between cavities."
                  },
                  {
                    "name": "Cerebral aqueduct",
                    "difference": "It connects the third and fourth ventricles, whereas the interventricular foramina connect the lateral ventricles with the third."
                  },
                  {
                    "name": "Median and lateral apertures of the fourth ventricle",
                    "difference": "These connect the fourth ventricle with the subarachnoid space, whereas the interventricular foramina connect ventricular cavities."
                  },
                  {
                    "name": "Interventricular foramen of the embryonic heart",
                    "difference": "This is a developmental communication between the cardiac ventricles, rather than an opening in the brain's ventricular system."
                  }
                ],
                "questions": [
                  {
                    "id": "evidence-neighbours-q01",
                    "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of interventricular foramina this model covers, and on what evidence?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should the registry concept formally cover homologous structures across species, and which anatomical differences require explicit qualification?",
    "Which age-specific reference measurements are sufficiently validated, and what section orientation and lumen-boundary convention do they require?",
    "What imaging evidence reliably distinguishes a very narrow patent foramen from complete occlusion when direct flow assessment is inconclusive?",
    "How should congenital variation, acquired narrowing and postoperative distortion be distinguished when baseline observations are unavailable?",
    "Which findings justify suspected intermittent obstruction, and how should uncertainty be represented when examinations capture only isolated time points?"
  ],
  "statistics": {
    "bundles": 6,
    "layers": 11,
    "findings": 15,
    "questions": 30
  }
}
