{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T10:29:41Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 18.5, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a09529-488c-7221-9f35-a455552db6e1\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: inferior colliculi\nSense to describe: (none recorded)\nDomain code: PHY.OBJ\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Batch 043: 1", "usd": 0.0, "recall": true }, "codex": { "seconds": 76.4, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a09529-487f-79e2-9537-71180007bd24\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: inferior colliculi\nRegistry id: vr.tr.inferior-colliculi\nPlane / domain: PHY / PHY.OBJ\nRegistry definition: (none recorded)\nNames folded into this en" } }, "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T12:00:00Z", "ingestedAt": "2026-10-06T08:48:01+00:00", "fields": [ "agent_conduct", "ethics", "failure_modes_and_hazards", "owners", "visual_identification" ] }, "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T10:10:30+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q358512", "registryId": "vr.tr.inferior-colliculi", "name": "inferior colliculi", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.OBJ" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q358512/", "model": { "registry_id": "vr.tr.inferior-colliculi", "name": "inferior colliculi", "purpose": "Enable an agent to identify the inferior colliculi, record their anatomical and auditory functional state, and assess whether observations support further investigation.", "definition": "The inferior colliculi are paired nuclei of the dorsal midbrain that form the lower part of the tectum and integrate ascending auditory information, relaying it chiefly to the medial geniculate bodies of the thalamus.", "scope_statement": "This model owns vr.tr.inferior-colliculi in PHY / PHY.OBJ: the paired auditory structures of the midbrain tectum, their constituent subdivisions, and observations attributable to either side or the pair, with species and measurement context explicitly recorded.", "in_scope": [ "The paired inferior colliculi and side-specific observations", "Anatomical boundaries, dimensions, and relationships to adjacent midbrain structures", "Internal subdivisions and their species-specific atlas assignments", "Ascending, descending, and intercollicular connections at their interfaces with these structures", "Localized auditory responses, tissue abnormalities, and changes over time" ], "out_of_scope": [ "The superior colliculi and their internal organization", "The whole midbrain or complete auditory system", "The cochlea, cochlear nuclei, and superior olivary complex as independent structures", "The medial geniculate bodies and auditory cortex as independent structures", "Hearing disorders as diagnoses and patient-level treatment decisions", "Imaging scanners, recording electrodes, and stimulation devices as equipment" ], "distinguishing_features": [ "An anatomical candidate must occupy the caudal tectal position below the superior colliculus in a species-appropriate reference, rather than merely show sound-evoked activity. [Anatomical reference](https://www.ncbi.nlm.nih.gov/books/NBK554468/)", "The plural entry represents the left and right inferior colliculi; a unilateral specimen or region of interest is a side-specific observation within that scope.", "The structure contains neural tissue organized into collicular subdivisions; the adjacent lateral lemniscus and brachium must not be mistaken for the entire structure.", "Its midbrain location distinguishes it from the medial geniculate body in the thalamus, even though both participate in auditory processing.", "A central-nucleus label identifies a constituent region, not the whole inferior colliculus; subdivision terminology must be checked against the selected atlas." ], "characteristics": [ { "name": "Biological context", "kind": "relation", "unit_or_values": "Species, subject or specimen identifier, developmental stage", "why_it_matters": "Constrains which anatomical references and physiological comparisons are applicable." }, { "name": "Observation laterality", "kind": "category", "unit_or_values": "Left; right; bilateral separately measured; bilateral pooled; unresolved", "why_it_matters": "Prevents pooled measurements from concealing unilateral differences." }, { "name": "Subdivision assignment", "kind": "category", "unit_or_values": "Central nucleus; dorsal cortex; external or lateral cortex under a named atlas; other atlas-defined region; unresolved", "why_it_matters": "Anatomical and functional interpretations depend on the sampled subdivision." }, { "name": "Anatomical extent", "kind": "measurement", "unit_or_values": "Volume in mm³ and dimensions in mm, with side, boundary method, and uncertainty", "why_it_matters": "Supports comparison of size and asymmetry without treating segmentation choices as biological differences." }, { "name": "Spatial localization", "kind": "measurement", "unit_or_values": "Coordinates in mm in a named reference space, with orientation and localization uncertainty", "why_it_matters": "Allows recordings, lesions, and image regions to be assigned to the correct tissue." }, { "name": "Connection evidence", "kind": "relation", "unit_or_values": "Source region, target region, direction, laterality, method, and evidence reference", "why_it_matters": "Separates demonstrated pathways from inferred associations." }, { "name": "Frequency response", "kind": "measurement", "unit_or_values": "Stimulus frequency in Hz; best frequency in Hz when established; sound level in dB with reference specified", "why_it_matters": "Characterizes auditory selectivity under a reproducible stimulus protocol." }, { "name": "Response timing", "kind": "measurement", "unit_or_values": "Latency and temporal response measures in ms, with recording modality and stimulus timing", "why_it_matters": "Distinguishes temporal response properties from spatial or frequency organization." }, { "name": "Observed tissue state", "kind": "state", "unit_or_values": "No abnormality detected by stated method; abnormality observed; indeterminate; not assessed", "why_it_matters": "Keeps negative observations distinct from untested tissue integrity." } ], "affordances": [ "Locate and annotate each inferior colliculus in an image or specimen using an identified anatomical reference.", "Assign a localized observation to a side and subdivision, preserving uncertain boundaries.", "Compare left and right measurements under matched acquisition and segmentation conditions.", "Relate auditory responses to stimulus frequency, timing, and ear-specific presentation.", "Map a localized abnormality against collicular subdivisions and documented pathway interfaces.", "Flag when localization, evidence quality, or protocol information is insufficient for a proposed interpretation or intervention." ], "agent_conduct": { "may": [ "Describe the inferior colliculi and their role in hearing from reliable sources.", "Label them on anatomical diagrams, brain atlases and educational images." ], "must_not": [ "Diagnose hearing or brain disorders involving the inferior colliculi in a particular person.", "Interpret an individual's brain scan as a clinical finding.", "Present identifiable patient imaging or case details without consent." ], "requires_human": [ "Any clinical decision about a lesion or condition affecting the midbrain." ] }, "ethics": { "considerations": [ "Misreading brain imaging can lead to wrong diagnoses and treatment.", "Animal research on the auditory midbrain raises welfare questions that need ethical review." ], "affected_parties": [ "Patients with hearing or brain disorders", "Clinicians", "Research animals" ] }, "owners": { "steward": "Nobody owns them; they are part of each person's body, and the treating clinician answers for their care.", "master_systems": [] }, "visual_identification": [ "Two rounded swellings on the back of the midbrain, below the larger superior colliculi.", "Together with the superior colliculi they form four bumps on the dorsal midbrain." ], "failure_modes_and_hazards": [ "Lesions from stroke, tumour or injury can disturb hearing and sound localization.", "Their small size makes findings on imaging easy to misread." ], "what_it_is_for": [ "The inferior colliculi are encountered in neuroanatomy, brain imaging and research on auditory processing.", "They integrate ascending auditory signals and relay information toward the thalamus.", "Their location and connections help clinicians and researchers interpret observations involving midbrain auditory pathways." ], "standards_and_regulation": [ "Terminologia Anatomica, issued by the Federative International Programme for Anatomical Terminology, provides standardized anatomical nomenclature for the inferior colliculus." ] }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q358512: inferior colliculi", "url": "https://www.wikidata.org/wiki/Q358512", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Inferior colliculus", "url": "https://en.wikipedia.org/wiki/Inferior_colliculus", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "tectal-identity", "name": "Tectal identity", "description": "Establishes which paired midbrain structures and biological instance the record concerns.", "rationale": "Auditory activity alone cannot identify inferior collicular tissue, and the plural registry entry must retain side-specific distinctions.", "layers": [ { "id": "paired-anatomical-reference", "name": "Paired anatomical reference", "description": "Anchors the registered kind to a subject or specimen and a laterality convention.", "findings": [ { "id": "pair-and-side-assignment", "name": "Pair and side assignment", "description": "Record whether evidence describes the pair, one side, or a pooled bilateral observation.", "questions": [ { "text": "Does this observation concern the left inferior colliculus, the right, or both?", "kind": "boundary", "id": "pair-and-side-assignment-q01" }, { "text": "Which species, subject or specimen, and developmental stage does it describe?", "kind": "provenance", "id": "pair-and-side-assignment-q02" } ] } ] }, { "id": "tectal-boundaries", "name": "Tectal boundaries", "description": "Separates inferior collicular tissue from neighboring tectal structures and fiber pathways.", "findings": [ { "id": "landmark-supported-identification", "name": "Landmark-supported identification", "description": "Use a named anatomical reference and visible landmarks to justify the outer boundary.", "questions": [ { "text": "Which landmarks distinguish this region from the superior colliculus and surrounding midbrain tissue?", "kind": "definition", "id": "landmark-supported-identification-q01" }, { "text": "Where does the segmentation exclude the brachium, lateral lemniscus, and neighboring periaqueductal tissue?", "kind": "boundary", "id": "landmark-supported-identification-q02" } ] } ] } ] }, { "id": "collicular-subdivisions", "name": "Collicular subdivisions", "description": "Represents internal parcellation and the evidence supporting regional assignments.", "rationale": "Whole-colliculus measurements cannot automatically stand in for central-nucleus or cortical-subdivision measurements.", "layers": [ { "id": "atlas-parcellation", "name": "Atlas parcellation", "description": "Preserves subdivision names and boundaries under the reference actually used.", "findings": [ { "id": "subdivision-nomenclature", "name": "Subdivision nomenclature", "description": "Record atlas-specific terminology without assuming external cortex and lateral cortex are universally interchangeable. Rat and cat work explicitly addresses these mapping differences. [Cytoarchitecture study](https://pubmed.ncbi.nlm.nih.gov/18313229/)", "questions": [ { "text": "Which atlas and species define the central nucleus and surrounding subdivisions in this record?", "kind": "provenance", "id": "subdivision-nomenclature-q01" }, { "text": "Do alternative subdivision names denote identical tissue boundaries in these references?", "kind": "boundary", "id": "subdivision-nomenclature-q02" } ] } ] }, { "id": "regional-morphometry", "name": "Regional morphometry", "description": "Captures side-specific size and shape at a resolution justified by the method.", "findings": [ { "id": "measured-collicular-extent", "name": "Measured collicular extent", "description": "Retain whole-structure and subdivision measurements separately, including segmentation uncertainty.", "questions": [ { "text": "What volume and dimensions were measured for each side, and which boundaries were used?", "kind": "measurement", "id": "measured-collicular-extent-q01" }, { "text": "Can the acquisition resolve subdivisions, or only the external collicular boundary?", "kind": "boundary", "id": "measured-collicular-extent-q02" } ] } ] } ] }, { "id": "auditory-pathway-interfaces", "name": "Auditory pathway interfaces", "description": "Records pathways entering, leaving, and linking the inferior colliculi.", "rationale": "Direction, laterality, and subdivision determine what a connection observation can explain.", "layers": [ { "id": "ascending-and-thalamic-connections", "name": "Ascending and thalamic connections", "description": "Describes interfaces with auditory brainstem sources and thalamic targets.", "findings": [ { "id": "directed-pathway-assignment", "name": "Directed pathway assignment", "description": "Record connection endpoints rather than attributing every auditory pathway to the whole colliculus. Rat tracing demonstrates subdivision-dependent sources of input. [Projection study](https://pubmed.ncbi.nlm.nih.gov/3624552/)", "questions": [ { "text": "Which brainstem source or medial geniculate target is linked to which side and subdivision?", "kind": "boundary", "id": "directed-pathway-assignment-q01" }, { "text": "What evidence establishes the connection and its direction?", "kind": "provenance", "id": "directed-pathway-assignment-q02" } ] } ] }, { "id": "descending-and-commissural-connections", "name": "Descending and commissural connections", "description": "Distinguishes cortical inputs and connections involving the opposite inferior colliculus.", "findings": [ { "id": "feedback-and-cross-side-evidence", "name": "Feedback and cross-side evidence", "description": "Preserve the origin, target, and laterality of each reported pathway. Cat tracing identifies subdivision-specific cortical projections, which require species-qualified interpretation. [Cortical projection study](https://pubmed.ncbi.nlm.nih.gov/9766397/)", "questions": [ { "text": "Is the reported connection cortical-to-collicular, intercollicular, or another directed pathway?", "kind": "definition", "id": "feedback-and-cross-side-evidence-q01" }, { "text": "Was laterality demonstrated directly, and in which species and experimental preparation?", "kind": "provenance", "id": "feedback-and-cross-side-evidence-q02" } ] } ] } ] }, { "id": "localized-auditory-function", "name": "Localized auditory function", "description": "Organizes stimulus-linked responses attributable to identified collicular tissue.", "rationale": "A response depends on stimulus design, recording scale, and sampled subdivision; an undifferentiated hearing score is insufficient.", "layers": [ { "id": "spectral-and-temporal-responses", "name": "Spectral and temporal responses", "description": "Records frequency selectivity and response timing without assuming every observation resolves individual neurons.", "findings": [ { "id": "stimulus-conditioned-response", "name": "Stimulus-conditioned response", "description": "Bind measured responses to stimulus parameters, anatomical location, and recording modality.", "questions": [ { "text": "Which frequencies, sound levels, durations, and repetition rates produced the measured response?", "kind": "measurement", "id": "stimulus-conditioned-response-q01" }, { "text": "Does the evidence measure single-unit activity, population activity, or an indirect imaging signal?", "kind": "provenance", "id": "stimulus-conditioned-response-q02" } ] } ] }, { "id": "ear-specific-response-comparison", "name": "Ear-specific response comparison", "description": "Captures responses to separately controlled stimulation of the two ears.", "findings": [ { "id": "binaural-test-conditions", "name": "Binaural test conditions", "description": "Record ear-specific timing and level manipulations before interpreting a response as sensitivity to spatial hearing cues.", "questions": [ { "text": "How did the response change with monaural versus binaural presentation?", "kind": "measurement", "id": "binaural-test-conditions-q01" }, { "text": "Which interaural time differences in µs or level differences in dB were tested?", "kind": "measurement", "id": "binaural-test-conditions-q02" } ] } ] } ] }, { "id": "collicular-integrity-and-action", "name": "Collicular integrity and action", "description": "Connects localized structural or functional changes to justified next steps.", "rationale": "An abnormal auditory result does not by itself localize dysfunction to the inferior colliculi or justify an intervention there.", "layers": [ { "id": "localized-abnormality", "name": "Localized abnormality", "description": "Documents observed tissue changes and their anatomical extent.", "findings": [ { "id": "abnormality-localization", "name": "Abnormality localization", "description": "Separate direct observations of collicular tissue from functional deficits attributed to it.", "questions": [ { "text": "Which side and subdivisions show an abnormality, and does it extend into adjacent tissue or pathways?", "kind": "boundary", "id": "abnormality-localization-q01" }, { "text": "What imaging, histological, or physiological evidence supports the observation and any change over time?", "kind": "provenance", "id": "abnormality-localization-q02" } ] } ] }, { "id": "interpretation-and-targeting", "name": "Interpretation and targeting", "description": "Determines whether available evidence supports annotation, comparison, further investigation, or review of a proposed target.", "findings": [ { "id": "evidence-bounded-next-step", "name": "Evidence-bounded next step", "description": "Make localization uncertainty and the responsible clinical or experimental protocol explicit before acting on collicular tissue.", "questions": [ { "text": "What additional observation would distinguish inferior-colliculus involvement from upstream or downstream auditory dysfunction?", "kind": "action", "id": "evidence-bounded-next-step-q01" }, { "text": "For proposed sampling or stimulation, are the target side, subdivision, localization uncertainty, and governing protocol established?", "kind": "action", "id": "evidence-bounded-next-step-q02" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "This entry describes the paired anatomical structures, not a device or a disease.", "Commonly distinguished subdivisions include the central nucleus, dorsal cortex, and external or lateral cortex; terminology and boundaries vary across species and anatomical accounts.", "Exact anatomical identifier codes and quantitative dimensions require verification; none are supplied from uncertain recall." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of inferior colliculi this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "Terminologia Anatomica", "value_or_pattern": "Colliculus inferior", "note": "Singular anatomical name; inferior colliculi denotes the paired structures." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of inferior colliculi this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Integrate auditory signals arriving from multiple brainstem pathways.", "Contribute to sound localization and the processing of sound frequency, intensity, and timing.", "Relay auditory information toward the thalamus and auditory cortex.", "Serve as anatomical landmarks in midbrain imaging and surgery." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of inferior colliculi this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Lesions can impair sound localization and other aspects of central auditory processing.", "Bilateral damage can cause severe hearing impairment; effects depend on lesion extent and involvement of adjacent auditory pathways.", "Their proximity to other midbrain structures makes nearby masses or surgical injury potentially disruptive to multiple neurological functions." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of inferior colliculi this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "Superior colliculi", "difference": "Lie above the inferior colliculi and primarily support orienting responses involving vision and other sensory inputs." }, { "name": "Medial geniculate bodies", "difference": "Are thalamic auditory relay structures receiving inferior-collicular output, rather than midbrain nuclei." }, { "name": "Lateral lemniscus", "difference": "Is an ascending auditory pathway with associated nuclei, carrying signals toward the inferior colliculus." }, { "name": "Central nucleus of the inferior colliculus", "difference": "Is a subdivision within each inferior colliculus, rather than the whole structure." }, { "name": "Inferior brachium", "difference": "Is the fiber connection linking the inferior colliculus with the medial geniculate region, rather than the collicular nucleus itself." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of inferior colliculi this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Does the registry intend a human anatomical default, or a cross-species concept requiring explicit homology mappings?", "Which anatomical atlas should govern subdivision boundaries, especially mappings between external and lateral cortex terminology?", "Which species-, age-, and method-specific reference datasets support meaningful judgments about size or left-right asymmetry?", "Which available measurement methods can reliably separate subdivisions and localize functional responses in the intended use setting?", "What evidence threshold should support attributing an auditory deficit specifically to unilateral or bilateral inferior-colliculus dysfunction?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 15, "questions": 25 } }