{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-14T02:52:00Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 4,
    "engine": "claude",
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-06T11:00:00Z",
      "ingestedAt": "2026-10-06T07:45:58+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "owners"
      ]
    },
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-06T19:52:00+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q43041",
    "registryId": "vr.tr.hemoglobin",
    "name": "hemoglobin",
    "version": "0.2.0-wave.4",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "PHY.MAT"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q43041/",
  "model": {
    "registry_id": "vr.tr.hemoglobin",
    "name": "hemoglobin",
    "purpose": "Let an agent explain haemoglobin, relay structure, function, forms, measurement and disorders from biochemistry and haematology sources, describe the named forms, route carbon monoxide and severe anaemia emergencies, and distinguish haemoglobin from myoglobin, other blood proteins and red blood cells themselves.",
    "definition": "The iron-containing protein in red blood cells that carries oxygen from the lungs to the tissues and helps transport carbon dioxide back, made of four globin chains each binding a heme group with iron, giving blood its red colour, with forms the registry aliases name such as fetal haemoglobin, oxyhaemoglobin, sulfhaemoglobin and named variants; haemoglobin levels are measured to diagnose anaemia and other conditions, and variants and disorders such as sickle cell disease and thalassaemia alter its structure or amount. Carbon monoxide binds haemoglobin far more strongly than oxygen, which is why carbon monoxide poisoning is dangerous and needs urgent care.",
    "what_it_is_for": "Carrying oxygen in the blood.",
    "affordances": [
      "explain structure and function",
      "relay forms and measurement",
      "describe named forms",
      "route emergencies"
    ],
    "distinguishing_features": [
      "Iron heme groups",
      "Four subunits",
      "Oxygen transport",
      "Red colour"
    ],
    "appearance": "Not visible directly; the red pigment of blood, studied as a protein.",
    "visual_identification": [
      "Iron-containing oxygen-carrying blood protein",
      "Fetal hemoglobin, oxyhemoglobin, sulfhemoglobin, hemoglobin variants",
      "Myoglobin stores oxygen in muscle; other blood proteins have other roles; red blood cells contain haemoglobin"
    ],
    "physical_properties": [
      {
        "quantity": "structure",
        "typical_range": "four globin chains with heme",
        "unit": "note",
        "note": ""
      },
      {
        "quantity": "carries",
        "typical_range": "oxygen and some carbon dioxide",
        "unit": "list",
        "note": ""
      },
      {
        "quantity": "registry parents",
        "typical_range": "globin, metalloprotein, protein",
        "unit": "note",
        "note": ""
      }
    ],
    "families_and_kinds": [
      "adult haemoglobin A",
      "fetal haemoglobin",
      "variant haemoglobins",
      "oxy and deoxyhaemoglobin"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "metalloprotein",
        "why": "in registry terms"
      },
      {
        "relation": "is contained in",
        "target": "red blood cell",
        "why": ""
      },
      {
        "relation": "is contrasted with",
        "target": "myoglobin",
        "why": ""
      },
      {
        "relation": "binds",
        "target": "oxygen",
        "why": ""
      }
    ],
    "identifiers": [],
    "standards_and_regulation": [
      "Laboratory reference ranges for haemoglobin",
      "Clinical guidelines for anaemia"
    ],
    "failure_modes_and_hazards": [
      "Carbon monoxide poisoning",
      "Severe anaemia",
      "Confusing haemoglobin and red cells"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": [],
    "agent_conduct": {
      "may": [
        "Explain haemoglobin and its role in oxygen transport.",
        "Explain what a haemoglobin test measures in general terms, with reference ranges stated as varying by laboratory."
      ],
      "must_not": [
        "Interpret a specific person's blood result as a diagnosis.",
        "Advise iron supplements or transfusion in place of a clinician.",
        "Share a person's blood test results without consent.",
        "Present haemoglobin variants as signs of ethnic origin in ways that stigmatise."
      ],
      "requires_human": [
        "Any treatment decision based on haemoglobin levels."
      ]
    },
    "ethics": {
      "considerations": [
        "Inherited haemoglobin disorders such as sickle cell disease affect communities who face discrimination in care.",
        "Blood results are private health data."
      ],
      "affected_parties": [
        "Patients",
        "People with sickle cell and thalassaemia",
        "Blood donors"
      ]
    },
    "owners": {
      "steward": "Nobody owns it; it is part of every person's blood.",
      "master_systems": []
    }
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q43041: hemoglobin",
      "url": "https://www.wikidata.org/wiki/Q43041",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Hemoglobin",
      "url": "https://en.wikipedia.org/wiki/Hemoglobin",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "understand",
        "name": "Understand",
        "description": "What haemoglobin is.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "definition",
            "name": "Definition",
            "description": "Definition.",
            "findings": [
              {
                "id": "definition-finding",
                "name": "Definition",
                "description": "Definition.",
                "questions": [
                  {
                    "text": "Is there suspected carbon monoxide poisoning or severe anaemia with breathlessness or fainting, in which case seek emergency care?",
                    "kind": "boundary"
                  },
                  {
                    "text": "What is haemoglobin, and how does it differ from myoglobin, other blood proteins and red blood cells?",
                    "kind": "definition"
                  }
                ]
              }
            ]
          },
          {
            "id": "forms",
            "name": "Forms",
            "description": "Named forms.",
            "findings": [
              {
                "id": "forms-finding",
                "name": "Forms",
                "description": "Forms.",
                "questions": [
                  {
                    "text": "What are fetal haemoglobin, oxyhaemoglobin and sulfhaemoglobin?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which entry fits the specific form?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "biochemistry",
        "name": "Biochemistry",
        "description": "Structure and function.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "structure",
            "name": "Structure",
            "description": "Structure.",
            "findings": [
              {
                "id": "structure-finding",
                "name": "Structure",
                "description": "Structure.",
                "questions": [
                  {
                    "text": "How do globin chains and heme groups bind oxygen?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which references are standard?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "cooperativity",
            "name": "Cooperativity",
            "description": "Oxygen binding.",
            "findings": [
              {
                "id": "cooperativity-finding",
                "name": "Cooperativity",
                "description": "Cooperativity.",
                "questions": [
                  {
                    "text": "How does cooperative binding shape the oxygen dissociation curve?",
                    "kind": "measurement"
                  },
                  {
                    "text": "Which sources are cited?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "clinical",
        "name": "Clinical",
        "description": "Measurement and disorders.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "measurement",
            "name": "Measurement",
            "description": "Haemoglobin tests.",
            "findings": [
              {
                "id": "measurement-finding",
                "name": "Measurement",
                "description": "Measurement.",
                "questions": [
                  {
                    "text": "How is haemoglobin measured to diagnose anaemia?",
                    "kind": "measurement"
                  },
                  {
                    "text": "Which entry fits anemia?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "disorders",
            "name": "Disorders",
            "description": "Haemoglobin disorders.",
            "findings": [
              {
                "id": "disorders-finding",
                "name": "Disorders",
                "description": "Disorders.",
                "questions": [
                  {
                    "text": "How do sickle cell disease and thalassaemia affect haemoglobin?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits hemoglobinopathy?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "context",
        "name": "Context",
        "description": "Carbon monoxide.",
        "rationale": "Attribution.",
        "layers": [
          {
            "id": "co",
            "name": "CO",
            "description": "Carbon monoxide.",
            "findings": [
              {
                "id": "co-finding",
                "name": "CO",
                "description": "CO.",
                "questions": [
                  {
                    "text": "Why does carbon monoxide bind haemoglobin so dangerously?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits carbon monoxide poisoning?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "evolution",
            "name": "Evolution",
            "description": "Oxygen carriers.",
            "findings": [
              {
                "id": "evolution-finding",
                "name": "Evolution",
                "description": "Evolution.",
                "questions": [
                  {
                    "text": "How do haemoglobin and other oxygen carriers compare across animals?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Is the presentation neutral and attributed?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should haemoglobin variants be linked to haemoglobinopathy entries?",
    "How should reference ranges be linked?",
    "Should fetal haemoglobin be a separate entry?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}
