{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-11T21:05:44Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 2,
    "engine": "claude",
    "enrichment": {
      "pass": 3,
      "engine": "claude",
      "producedAt": "2026-10-05T23:50:00Z",
      "ingestedAt": "2026-10-05T20:47:55+00:00",
      "fields": [
        "agent_conduct",
        "ethics",
        "owners"
      ]
    },
    "gate": {
      "passed": true,
      "version": "1.0",
      "at": "2026-10-06T19:52:00+00:00",
      "evidence": [
        "completeness 1.00",
        "sense: Wikidata description",
        "2 live sources",
        "review by codex: pass"
      ]
    }
  },
  "metaModel": {
    "id": "THING-Q490123",
    "registryId": "vr.tr.causes-of-schizophrenia",
    "name": "causes of schizophrenia",
    "version": "0.2.0-wave.2",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "XCT.REL"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q490123/",
  "model": {
    "registry_id": "vr.tr.causes-of-schizophrenia",
    "name": "causes of schizophrenia",
    "purpose": "Let an agent explain current evidence on the causes of schizophrenia with attribution and appropriate uncertainty, avoid stigma and determinism, and route personal concerns to professional care.",
    "definition": "The factors that contribute to the development of schizophrenia, understood as a complex interaction of genetic predisposition, neurodevelopmental factors, prenatal and early-life influences, substance use such as cannabis, stress and social environment, with no single cause; research spans genetics, epigenetics, neuroscience and epidemiology, and findings are probabilistic rather than deterministic.",
    "what_it_is_for": "Understanding a complex mental health condition.",
    "affordances": [
      "summarise evidence on causes with attribution",
      "explain genetic and environmental interaction",
      "address myths and stigma",
      "route personal concerns to care"
    ],
    "distinguishing_features": [
      "Multifactorial",
      "Probabilistic",
      "Actively researched",
      "Stigma-sensitive"
    ],
    "appearance": "Not physical; a body of research findings.",
    "visual_identification": [
      "Multifactorial causation",
      "Risk factors, not single causes",
      "Symptoms and diagnosis are separate topics"
    ],
    "physical_properties": [],
    "families_and_kinds": [
      "genetic factors",
      "neurodevelopmental and prenatal factors",
      "environmental and social factors",
      "substance-related factors",
      "evolutionary hypotheses"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "causes of mental disorders",
        "why": "category"
      },
      {
        "relation": "is related to",
        "target": "psychosis",
        "why": "associated condition"
      },
      {
        "relation": "is related to",
        "target": "cause",
        "why": "causal reasoning"
      },
      {
        "relation": "is studied by",
        "target": "neuroscience",
        "why": "field"
      }
    ],
    "identifiers": [],
    "standards_and_regulation": [
      "Clinical guidelines on schizophrenia",
      "Research ethics for genetic studies"
    ],
    "failure_modes_and_hazards": [
      "Deterministic or stigmatising claims",
      "Blaming families",
      "Agents diagnosing or advising on treatment"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": [],
    "agent_conduct": {
      "may": [
        "Explain current research on the causes of schizophrenia with sources and stated uncertainty.",
        "Point people to mental health services."
      ],
      "must_not": [
        "Blame parents or families as the cause of a person's schizophrenia.",
        "Predict whether a specific person will develop schizophrenia.",
        "Present a single factor as the cause.",
        "Use cause explanations to stigmatise people with schizophrenia."
      ],
      "requires_human": [
        "Any advice about genetic testing or family planning on this basis."
      ]
    },
    "ethics": {
      "considerations": [
        "Discredited theories once blamed families and caused lasting harm.",
        "People with schizophrenia face heavy stigma."
      ],
      "affected_parties": [
        "People with schizophrenia",
        "Families",
        "Clinicians and researchers"
      ]
    },
    "owners": {
      "steward": "Nobody: a body of research held by the scientific community.",
      "master_systems": []
    }
  },
  "sources": [
    {
      "id": "wikidata",
      "title": "Wikidata item Q490123: causes of schizophrenia",
      "url": "https://www.wikidata.org/wiki/Q490123",
      "url_status": "live",
      "what_it_supports": "identity and sense of the item",
      "checked_by": "wikidata-api"
    },
    {
      "id": "wikipedia-en",
      "title": "Wikipedia: Risk factors of schizophrenia",
      "url": "https://en.wikipedia.org/wiki/Risk_factors_of_schizophrenia",
      "url_status": "live",
      "what_it_supports": "general description of the item",
      "checked_by": "wikidata-api sitelink"
    }
  ],
  "structure": {
    "bundles": [
      {
        "id": "evidence",
        "name": "Evidence",
        "description": "What research says.",
        "rationale": "Attribution and uncertainty.",
        "layers": [
          {
            "id": "factors",
            "name": "Factors",
            "description": "Risk factors.",
            "findings": [
              {
                "id": "factors-finding",
                "name": "Factors",
                "description": "Risk factors.",
                "questions": [
                  {
                    "text": "What do current reviews say about genetic, developmental and environmental contributions to schizophrenia?",
                    "kind": "provenance"
                  },
                  {
                    "text": "How large are the effects, and how uncertain are they?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "interaction",
            "name": "Interaction",
            "description": "Gene-environment interaction.",
            "findings": [
              {
                "id": "interaction-finding",
                "name": "Interaction",
                "description": "Interaction.",
                "questions": [
                  {
                    "text": "How do genetic and environmental factors interact, according to research?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which hypotheses, such as neurodevelopmental models, are prominent?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "care",
        "name": "Care",
        "description": "Personal concerns.",
        "rationale": "Route to professionals.",
        "layers": [
          {
            "id": "worried",
            "name": "Worried",
            "description": "Concern about risk.",
            "findings": [
              {
                "id": "worried-finding",
                "name": "Worried",
                "description": "Concern.",
                "questions": [
                  {
                    "text": "Is the user worried about their own or a relative risk, and should they speak to a clinician or genetic counsellor?",
                    "kind": "boundary"
                  },
                  {
                    "text": "Are early warning signs present that warrant assessment?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "crisis",
            "name": "Crisis",
            "description": "Crisis.",
            "findings": [
              {
                "id": "crisis-finding",
                "name": "Crisis",
                "description": "Crisis.",
                "questions": [
                  {
                    "text": "Is anyone in crisis or at risk now?",
                    "kind": "boundary"
                  },
                  {
                    "text": "Which services should be contacted?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "stigma",
        "name": "Stigma",
        "description": "Myths and language.",
        "rationale": "Respect.",
        "layers": [
          {
            "id": "myths",
            "name": "Myths",
            "description": "Common misconceptions.",
            "findings": [
              {
                "id": "myths-finding",
                "name": "Myths",
                "description": "Myths.",
                "questions": [
                  {
                    "text": "Which common beliefs about the causes of schizophrenia are unsupported, such as blaming parenting?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Is language non-stigmatising?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "substances",
            "name": "Substances",
            "description": "Substance use.",
            "findings": [
              {
                "id": "substances-finding",
                "name": "Substances",
                "description": "Substances.",
                "questions": [
                  {
                    "text": "What does evidence say about cannabis and other substances as risk factors?",
                    "kind": "provenance"
                  },
                  {
                    "text": "How is this communicated without moralising?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "research",
        "name": "Research",
        "description": "Ongoing research.",
        "rationale": "Frontiers.",
        "layers": [
          {
            "id": "directions",
            "name": "Directions",
            "description": "Research directions.",
            "findings": [
              {
                "id": "directions-finding",
                "name": "Directions",
                "description": "Directions.",
                "questions": [
                  {
                    "text": "What are current research directions, such as genomics, epigenetics and immune hypotheses?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which findings are contested?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "participate",
            "name": "Participate",
            "description": "Research participation.",
            "findings": [
              {
                "id": "participate-finding",
                "name": "Participate",
                "description": "Participation.",
                "questions": [
                  {
                    "text": "How can people participate in schizophrenia research ethically?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which registries exist?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should schizophrenia itself be a separate entry?",
    "How should research reviews be linked?",
    "How should stigma guidance be linked?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}