{ "vercy": "1.0-draft", "publication": { "status": "research-draft", "adjudicationStatus": "unreviewed", "publishableCanonical": false, "generatedAt": "2026-09-12T09:11:41Z", "providers": [ "Codex" ], "breadth": "recalled by Codex without web access - no source was read", "missingProviders": [], "pass": 2, "cost": { "grok": { "seconds": 18.7, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a094e0-fa91-7a02-8eb6-08b39e087c7f\n--------\nuser\nDescribe what is already known about one registered thing. Answer as JSON only, no prose around it.\n\nThing: diglycolic acid\nSense to describe: (none recorded)\nDomain code: PHY.MAT\nAlso known as: (none)\n\n\nContext for this batch of 1001 things:\n# Batch 043: 1001", "usd": 0.0, "recall": true }, "codex": { "seconds": 134.7, "error": "Reading additional input from stdin...\nOpenAI Codex v0.153.4\n--------\nworkdir: R:\\02_PROJECTS\\02_Meta_Models_Platforms\\Ver.cy\\current\\thing-registry-backlog\nmodel: gpt-6-astra\nprovider: openai\napproval: never\nsandbox: read-only\nreasoning effort: none\nreasoning summaries: none\nsession id: 01a094e0-fa85-7d71-b586-70e48f8c57ca\n--------\nuser\nYou are drafting a Vercy meta-model for one registered thing. Answer as JSON only, no prose around it.\n\nThing: diglycolic acid\nRegistry id: vr.tr.diglycolic-acid\nPlane / domain: PHY / PHY.MAT\nRegistry definition: (none recorded)\nNames folded into this entry: (" } }, "enrichment": { "pass": 3, "engine": "claude", "producedAt": "2026-10-06T12:00:00Z", "ingestedAt": "2026-10-06T08:55:04+00:00", "fields": [ "agent_conduct", "ethics", "failure_modes_and_hazards", "owners", "standards_and_regulation", "visual_identification" ] }, "gate": { "passed": true, "version": "1.0", "at": "2026-10-07T10:10:31+00:00", "evidence": [ "completeness 1.00", "sense: Wikidata description", "2 live sources", "review by codex: pass" ] } }, "metaModel": { "id": "THING-Q5276305", "registryId": "vr.tr.diglycolic-acid", "name": "diglycolic acid", "version": "0.1.0-research.1", "entryKind": "thing", "family": "Thing Registry", "domain": [ "PHY.MAT" ], "status": "research-draft" }, "canonicalUrl": "https://ver.cy/models/thing/q5276305/", "model": { "registry_id": "vr.tr.diglycolic-acid", "name": "diglycolic acid", "purpose": "Enable an agent to identify diglycolic acid, assess the composition and condition of a sample, and determine whether evidence supports its intended handling or use.", "definition": "Diglycolic acid is an ether-containing dicarboxylic acid with the structure HOOC-CH2-O-CH2-COOH and molecular formula C4H6O5.", "scope_statement": "This model owns the substance identity and sample-level assessment of diglycolic acid, registry entry vr.tr.diglycolic-acid in PHY / PHY.MAT, including purity, physical state, acid-base behavior, analytical evidence and applicable hazards.", "in_scope": [ "Molecular identity and verified identifiers for the free acid", "Sample grade, assay basis, water content and impurities", "Physical properties with measurement conditions", "Dissociation and solution composition", "Evidence supporting handling, storage and intended use" ], "out_of_scope": [ "Diethylene glycol and glycolic acid as separate substances", "Isolated diglycolate salts, esters, amides and diglycolic anhydride", "Manufacturing processes and their equipment", "Commercial formulations containing diglycolic acid", "Patient diagnosis and treatment of poisoning" ], "distinguishing_features": [ "Require the connectivity HOOC-CH2-O-CH2-COOH: two carboxylic acid groups joined through an ether-containing backbone. Formula alone is insufficient. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/Diglycolic-Acid)", "Cross-check CAS 110-99-6 and PubChem CID 8088 against the structure; oxydiacetic acid and 2,2'-oxydiacetic acid are identity aliases. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/Diglycolic-Acid)", "Reject a glycolic-acid match if the candidate lacks the second carboxymethyl arm and central ether linkage required by the diglycolic-acid structure.", "Reject a diethylene-glycol match if terminal groups are alcohols rather than the two carboxylic acids required here.", "Distinguish the free acid from an isolated salt or covalent derivative by counterions, protonation and functional-group connectivity; record solution dissociation without automatically treating it as a different purchased substance." ], "characteristics": [ { "name": "Molecular identity", "kind": "category", "unit_or_values": "C4H6O5; HOOC-CH2-O-CH2-COOH; molar mass 134.09 g/mol. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/Diglycolic-Acid)", "why_it_matters": "Anchors recognition and conversion between sample mass and amount of substance." }, { "name": "Registry identity", "kind": "relation", "unit_or_values": "vr.tr.diglycolic-acid; CAS 110-99-6; PubChem CID 8088; EC identifier pending verification", "why_it_matters": "Connects evidence to the correct substance rather than a similarly named material." }, { "name": "Assay and grade", "kind": "measurement", "unit_or_values": "Mass % with as-received or dry basis, method, uncertainty and grade specification", "why_it_matters": "Determines usable acid content and whether a batch meets its intended specification." }, { "name": "Water and impurity profile", "kind": "measurement", "unit_or_values": "Water in mass %; identified impurities in mg/kg or mass %; method-specific detection limits", "why_it_matters": "Separates dilution from chemical contamination and supports accurate dosing." }, { "name": "Physical and thermal condition", "kind": "state", "unit_or_values": "Observed phase, temperature in °C, pressure in kPa and evidence of thermal change", "why_it_matters": "Prevents reference properties from being applied to samples under incompatible conditions." }, { "name": "Dissolution capacity", "kind": "measurement", "unit_or_values": "Solubility in g/L or mol/L with solvent, temperature, pH and concentration basis", "why_it_matters": "Supports preparation of solutions without assuming complete dissolution." }, { "name": "Acid-base condition", "kind": "measurement", "unit_or_values": "pH, total analytical concentration in mol/L, pKa1 and pKa2 with temperature and ionic strength", "why_it_matters": "Distinguishes total diglycolic-acid-derived material from its individual protonation states." }, { "name": "Hazard and regulatory evidence", "kind": "relation", "unit_or_values": "Applicable SDS, GHS jurisdiction, classification date, exposure-limit source and transport assessment", "why_it_matters": "Makes handling decisions traceable to the actual material and applicable jurisdiction." } ], "affordances": [ "Resolve a label or identifier to diglycolic acid and flag conflicting structure evidence.", "Assess a batch against a defined assay, water and impurity specification.", "Calculate free-acid equivalents from sample mass using the documented assay basis.", "Evaluate whether a proposed solution concentration is supported by solubility and speciation evidence.", "Select identity and purity checks appropriate to the sample matrix.", "Determine whether documented hazards and material conditions support a proposed handling or storage action." ], "agent_conduct": { "may": [ "Describe diglycolic acid's chemistry and industrial uses.", "Explain its role as the toxic metabolite in diethylene glycol poisoning." ], "must_not": [ "Handle it without the protective equipment its safety data sheet requires.", "Advise or tolerate the substitution of diethylene glycol for safe excipients in medicines.", "Dispose of it into drains or general rubbish." ], "requires_human": [ "Investigations of suspected poisoning, which belong to clinicians and authorities." ] }, "ethics": { "considerations": [ "Contaminated medicines containing diethylene glycol have killed many children, so supply chain honesty is vital." ], "affected_parties": [ "Children given contaminated medicines", "Families", "Workers" ] }, "owners": { "steward": "The business or laboratory that holds it; the supplier answers for its labelling.", "master_systems": [] }, "visual_identification": [ "A white crystalline solid; identity needs analysis and a reliable label." ], "failure_modes_and_hazards": [ "Kidney damage as the toxic metabolite of diethylene glycol.", "Irritates eyes and skin." ], "standards_and_regulation": [ "Globally Harmonized System of Classification and Labelling of Chemicals (GHS), United Nations." ], "what_it_is_for": [ "Diglycolic acid is encountered as a laboratory reagent and an intermediate in chemical synthesis.", "It also occurs in analytical and toxicological research concerned with products of diethylene glycol metabolism." ] }, "sources": [ { "id": "wikidata", "title": "Wikidata item Q5276305: diglycolic acid", "url": "https://www.wikidata.org/wiki/Q5276305", "url_status": "live", "what_it_supports": "identity and sense of the item", "checked_by": "wikidata-api" }, { "id": "wikipedia-en", "title": "Wikipedia: Diglycolic acid", "url": "https://en.wikipedia.org/wiki/Diglycolic_acid", "url_status": "live", "what_it_supports": "general description of the item", "checked_by": "wikidata-api sitelink" } ], "structure": { "bundles": [ { "id": "identity-and-substance-boundary", "name": "Identity and substance boundary", "description": "Establish what qualifies as diglycolic acid and where neighbouring substance models begin.", "rationale": "Similar names and acid-derived forms can produce incorrect identity matches.", "layers": [ { "id": "structure-and-identifiers", "name": "Structure and identifiers", "description": "Connect the registered thing to a molecular structure and authoritative records.", "findings": [ { "id": "ether-linked-diacid", "name": "Ether-linked diacid identity", "description": "Recognition requires agreement between identifiers and the two carboxymethyl groups linked by an ether oxygen.", "questions": [ { "text": "Does the candidate structure match HOOC-CH2-O-CH2-COOH?", "kind": "definition", "id": "ether-linked-diacid-q01" }, { "text": "Which inspected records support the CAS, PubChem and EC identifiers, and do they identify the same free acid?", "kind": "provenance", "id": "ether-linked-diacid-q02" } ] } ] }, { "id": "acid-and-derived-forms", "name": "Acid and derived forms", "description": "Separate the free acid from related compounds while retaining useful solution-state relationships.", "findings": [ { "id": "free-acid-boundary", "name": "Free-acid boundary", "description": "Counterions, covalent modifications and the distinction between dissolved species and isolated substances determine model ownership.", "questions": [ { "text": "Is the material supplied as free diglycolic acid, an isolated diglycolate salt or a covalent derivative?", "kind": "boundary", "id": "free-acid-boundary-q01" }, { "text": "Does a reported diglycolate measurement describe dissociation in solution or a separately identified substance?", "kind": "definition", "id": "free-acid-boundary-q02" } ] } ] } ] }, { "id": "batch-composition-and-verification", "name": "Batch composition and verification", "description": "Establish how much diglycolic acid a sample contains and how that conclusion was reached.", "rationale": "A correct label does not establish purity or usable acid content.", "layers": [ { "id": "assay-and-water", "name": "Assay and water", "description": "Interpret batch composition on a consistent mass basis.", "findings": [ { "id": "usable-acid-content", "name": "Usable acid content", "description": "Assay, water and concentration basis must be reconciled before calculating an amount of diglycolic acid.", "questions": [ { "text": "What are the measured assay and water content, and are they reported on an as-received or dry basis?", "kind": "measurement", "id": "usable-acid-content-q01" }, { "text": "What sample mass supplies the required free-acid equivalents after the documented corrections?", "kind": "action", "id": "usable-acid-content-q02" } ] } ] }, { "id": "analytical-specificity", "name": "Analytical specificity", "description": "Assess whether measurements distinguish diglycolic acid from other components.", "findings": [ { "id": "identity-versus-acidity", "name": "Identity versus total acidity", "description": "An acid-content result requires separate consideration of molecular specificity and interference.", "questions": [ { "text": "Which structural or separation evidence distinguishes diglycolic acid from glycolic acid, diethylene glycol and other plausible sample components?", "kind": "measurement", "id": "identity-versus-acidity-q01" }, { "text": "Could other acids contribute to the reported titration assay, and what independent evidence constrains that contribution?", "kind": "measurement", "id": "identity-versus-acidity-q02" } ] } ] } ] }, { "id": "phase-and-solution-state", "name": "Phase and solution state", "description": "Describe the material under the actual thermal and solvent conditions of use.", "rationale": "Phase, thermal events and dissolution limits determine whether a proposed operation is physically supported.", "layers": [ { "id": "thermal-behavior", "name": "Thermal behavior", "description": "Keep measured transitions distinct from degradation and unsupported property estimates.", "findings": [ { "id": "interpretable-thermal-events", "name": "Interpretable thermal events", "description": "A melting, boiling or decomposition claim needs conditions and a method that supports its interpretation.", "questions": [ { "text": "What melting interval is supported for the stated purity and heating method?", "kind": "measurement", "id": "interpretable-thermal-events-q01" }, { "text": "Does a reported high-temperature event represent boiling, decomposition or another transformation, and at what pressure?", "kind": "measurement", "id": "interpretable-thermal-events-q02" } ] } ] }, { "id": "dissolution-and-concentration", "name": "Dissolution and concentration", "description": "Assess whether a specified solvent system contains a homogeneous solution.", "findings": [ { "id": "supported-solution-preparation", "name": "Supported solution preparation", "description": "Solution preparation requires evidence for the relevant solvent, temperature, concentration and acid-base conditions.", "questions": [ { "text": "What measured solubility supports the target concentration in the chosen solvent at the operating temperature and pH?", "kind": "measurement", "id": "supported-solution-preparation-q01" }, { "text": "How will incomplete dissolution or precipitation after cooling be detected before use?", "kind": "action", "id": "supported-solution-preparation-q02" } ] } ] } ] }, { "id": "diacid-speciation-and-interactions", "name": "Diacid speciation and interactions", "description": "Track protonation and assess interactions relevant to the intended solution or reaction.", "rationale": "Two acid groups and an ether oxygen make protonation and possible coordination important to investigate.", "layers": [ { "id": "stepwise-dissociation", "name": "Stepwise dissociation", "description": "Relate total concentration to neutral, singly deprotonated and doubly deprotonated forms.", "findings": [ { "id": "condition-dependent-speciation", "name": "Condition-dependent speciation", "description": "Species fractions require supported dissociation constants and solution conditions rather than name-based assumptions.", "questions": [ { "text": "Which measured pKa1 and pKa2 values apply at the relevant temperature and ionic strength?", "kind": "measurement", "id": "condition-dependent-speciation-q01" }, { "text": "Given pH and total concentration, what protonation-state distribution is supported and with what uncertainty?", "kind": "measurement", "id": "condition-dependent-speciation-q02" } ] } ] }, { "id": "counterions-and-metal-interactions", "name": "Counterions and metal interactions", "description": "Evaluate whether other dissolved components alter the intended behavior.", "findings": [ { "id": "interaction-evidence", "name": "Interaction evidence", "description": "Metal binding, salt formation and precipitation remain conditional claims requiring evidence for the actual system.", "questions": [ { "text": "Which counterions or metal ions are present, and what evidence supports complexation or precipitation under these conditions?", "kind": "measurement", "id": "interaction-evidence-q01" }, { "text": "Would neutralization or metal addition create a separately identified material requiring a linked model?", "kind": "boundary", "id": "interaction-evidence-q02" } ] } ] } ] }, { "id": "hazards-and-use-decisions", "name": "Hazards and use decisions", "description": "Connect substance-specific hazard evidence to the actual material and proposed action.", "rationale": "Identity alone cannot establish handling requirements, exposure limits or fitness for use.", "layers": [ { "id": "classification-and-toxicology", "name": "Classification and toxicology", "description": "Distinguish regulatory classifications from experimental biological findings.", "findings": [ { "id": "traceable-hazard-assessment", "name": "Traceable hazard assessment", "description": "Hazard conclusions require explicit sources, exposure context and applicability to the supplied material.", "questions": [ { "text": "Which current SDS and jurisdiction-specific GHS classification apply to this grade and concentration?", "kind": "provenance", "id": "traceable-hazard-assessment-q01" }, { "text": "What primary evidence establishes renal toxicity associated with diglycolic acid, and what exposure routes and experimental systems limit its interpretation?", "kind": "provenance", "id": "traceable-hazard-assessment-q02" } ] } ] }, { "id": "handling-and-fitness", "name": "Handling and fitness", "description": "Determine whether available evidence supports storage, transfer and intended use.", "findings": [ { "id": "evidence-based-use-gate", "name": "Evidence-based use gate", "description": "Decisions combine batch specification, physical form, compatibility and applicable handling guidance.", "questions": [ { "text": "What controls and storage conditions does the applicable SDS require for the actual solid or solution?", "kind": "action", "id": "evidence-based-use-gate-q01" }, { "text": "Which assay, impurity or compatibility requirement would prevent this batch from serving its intended use?", "kind": "action", "id": "evidence-based-use-gate-q02" }, { "text": "Are substance-specific exposure limits and transport classifications established in the relevant jurisdiction, or is their status unverified?", "kind": "provenance", "id": "evidence-based-use-gate-q03" } ] } ] } ] }, { "id": "evidence-and-external-alignment", "name": "Evidence and external alignment", "description": "What the world already says about this thing, gathered so the model can be checked against it.", "rationale": "A model that cannot be lined up against existing standards, identifiers and practice cannot be adopted by anyone who already uses them.", "layers": [ { "id": "reported-evidence", "name": "Reported evidence", "description": "Findings from the breadth pass, kept separate from the structural claims.", "findings": [ { "id": "evidence-confidence-notes", "name": "Check these first", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "This is recalled information; no sources were consulted.", "Verify melting point, solubility and acid dissociation constants under specified measurement conditions.", "Verify jurisdiction-specific hazard classifications and distinguish the free acid from salts, derivatives and commercial mixtures." ], "questions": [ { "id": "evidence-confidence-notes-q01", "text": "Which of these check these first hold for the sense of diglycolic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-identifiers", "name": "Identifiers and schemes", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "scheme": "CAS Registry Number", "value_or_pattern": "110-99-6", "note": "Identifies diglycolic acid." }, { "scheme": "Systematic chemical nomenclature", "value_or_pattern": "2,2'-Oxydiacetic acid", "note": "Also called oxydiacetic acid." }, { "scheme": "Molecular formula", "value_or_pattern": "C4H6O5", "note": "Describes composition but does not uniquely identify molecular connectivity." } ], "questions": [ { "id": "evidence-identifiers-q01", "text": "Which of these identifiers and schemes hold for the sense of diglycolic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-real-world-use", "name": "Real-world use", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Intermediate for preparing diglycolic acid derivatives, including esters and amides.", "Ligand in coordination chemistry through its carboxylate and ether oxygen donor sites." ], "questions": [ { "id": "evidence-real-world-use-q01", "text": "Which of these real-world use hold for the sense of diglycolic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-measurements", "name": "Typical measurements", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "quantity": "Molar mass", "typical_range": "134.09", "unit": "g/mol" } ], "questions": [ { "id": "evidence-measurements-q01", "text": "Which of these typical measurements hold for the sense of diglycolic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-failure-modes-and-hazards", "name": "Failure modes and hazards", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ "Diglycolic acid is a nephrotoxic metabolite implicated in kidney injury following diethylene glycol exposure." ], "questions": [ { "id": "evidence-failure-modes-and-hazards-q01", "text": "Which of these failure modes and hazards hold for the sense of diglycolic acid this model covers, and on what evidence?", "kind": "provenance" } ] }, { "id": "evidence-neighbours", "name": "Neighbouring kinds and how to tell them apart", "description": "Recalled without web access and unsourced; every item is a lead to verify.", "evidence": [ { "name": "Diethylene glycol", "difference": "Has terminal alcohol groups where diglycolic acid has carboxylic acid groups." }, { "name": "Glycolic acid", "difference": "Has one carboxyl group and one hydroxyl group; diglycolic acid has two carboxyl groups linked through an ether-containing backbone." }, { "name": "Diglycolate salts", "difference": "Contain partially or fully deprotonated diglycolic acid with counterions, rather than the neutral free acid." } ], "questions": [ { "id": "evidence-neighbours-q01", "text": "Which of these neighbouring kinds and how to tell them apart hold for the sense of diglycolic acid this model covers, and on what evidence?", "kind": "provenance" } ] } ] } ] } ] }, "openQuestions": [ "Which EC identifier and jurisdiction-specific regulatory records are verified for the free acid rather than a salt or formulation?", "What reliable measurements establish melting behavior, decomposition behavior and whether a meaningful boiling point is available?", "Which solubility and stepwise dissociation measurements cover the intended solvent, temperature and ionic strength?", "Which impurities are relevant to the actual supplier route and intended use, and which analytical methods adequately distinguish them?", "What current hazard classifications, exposure limits and primary toxicology evidence apply, and where do sources disagree or leave gaps?" ], "statistics": { "bundles": 6, "layers": 11, "findings": 16, "questions": 27 } }