{
  "vercy": "1.0-draft",
  "publication": {
    "status": "research-draft",
    "adjudicationStatus": "unreviewed",
    "publishableCanonical": false,
    "generatedAt": "2026-09-13T13:48:29Z",
    "providers": [
      "Claude"
    ],
    "breadth": "written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify",
    "pass": 2,
    "wave": 4,
    "engine": "claude"
  },
  "metaModel": {
    "id": "THING-Q958938",
    "registryId": "vr.tr.organogenesis",
    "name": "organogenesis",
    "version": "0.2.0-wave.4",
    "entryKind": "thing",
    "family": "Thing Registry",
    "domain": [
      "ACT.PRC"
    ],
    "status": "research-draft"
  },
  "canonicalUrl": "https://ver.cy/models/thing/q958938/",
  "model": {
    "registry_id": "vr.tr.organogenesis",
    "name": "organogenesis",
    "purpose": "Let an agent explain organogenesis in animals and plants, relay mechanisms, timelines and examples from developmental biology sources, describe sex differentiation and organ maturity in general terms, and distinguish organogenesis from gastrulation, morphogenesis in general, growth and regeneration.",
    "definition": "The formation of organs during development, in animals from the germ layers after gastrulation through processes such as musculoskeletal development and sex differentiation into male and female reproductive organs, continuing to fetal organ maturity before birth, and in plants the continuous formation of leaves, roots and flowers from meristems throughout life; organogenesis is a central topic of developmental biology and regenerative medicine.",
    "what_it_is_for": "Not applicable; a developmental process.",
    "affordances": [
      "explain mechanisms",
      "relay timelines and examples",
      "describe sex differentiation and maturity",
      "distinguish related processes"
    ],
    "distinguishing_features": [
      "Organ formation",
      "Germ layer origins",
      "Signalling and gene networks",
      "Continuous in plants"
    ],
    "appearance": "Not a visible object; organs forming in embryos and plants.",
    "visual_identification": [
      "Formation of organs in development",
      "Musculoskeletal development, male and female sex differentiation, fetal organ maturity, plant organogenesis",
      "Gastrulation forms germ layers; morphogenesis is shaping in general; growth is size increase; regeneration replaces parts"
    ],
    "physical_properties": [
      {
        "quantity": "human organogenesis period",
        "typical_range": "weeks 3 to 8",
        "unit": "note",
        "note": "embryonic"
      },
      {
        "quantity": "sex differentiation onset",
        "typical_range": "about week 7",
        "unit": "note",
        "note": "human"
      },
      {
        "quantity": "plant meristems",
        "typical_range": "shoot and root apical meristems",
        "unit": "list",
        "note": ""
      }
    ],
    "families_and_kinds": [
      "organogenesis of the heart, lungs, kidneys and gut",
      "neural and sensory organ development",
      "musculoskeletal development",
      "sex differentiation including male and female pathways",
      "fetal organ maturation",
      "plant organogenesis from meristems"
    ],
    "related_models": [
      {
        "relation": "is a kind of",
        "target": "biological process",
        "why": "in registry terms"
      },
      {
        "relation": "follows",
        "target": "gastrulation",
        "why": "in animal development"
      },
      {
        "relation": "is studied in",
        "target": "developmental biology",
        "why": ""
      },
      {
        "relation": "is mimicked in",
        "target": "organoid",
        "why": "research"
      }
    ],
    "identifiers": [
      {
        "scheme": "GO",
        "value_or_pattern": "GO:0048513",
        "note": "animal organ development"
      }
    ],
    "standards_and_regulation": [
      "Ethics rules on embryo research",
      "No regulation of the process itself"
    ],
    "failure_modes_and_hazards": [
      "Birth defects from disrupted organogenesis",
      "Agents giving personal medical advice about pregnancy",
      "Registry aliases mixing animal, human and plant processes"
    ],
    "in_scope": [],
    "out_of_scope": [],
    "characteristics": []
  },
  "sources": [],
  "structure": {
    "bundles": [
      {
        "id": "understand",
        "name": "Understand",
        "description": "What organogenesis is.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "definition",
            "name": "Definition",
            "description": "Definition.",
            "findings": [
              {
                "id": "definition-finding",
                "name": "Definition",
                "description": "Definition.",
                "questions": [
                  {
                    "text": "What is organogenesis, and how does it differ from gastrulation, morphogenesis, growth and regeneration?",
                    "kind": "definition"
                  },
                  {
                    "text": "Is the question about animals, humans, plants or a pregnancy matter needing a clinician?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "processes",
            "name": "Processes",
            "description": "Processes.",
            "findings": [
              {
                "id": "processes-finding",
                "name": "Processes",
                "description": "Processes.",
                "questions": [
                  {
                    "text": "What are musculoskeletal development, sex differentiation, fetal organ maturity and plant organogenesis?",
                    "kind": "definition"
                  },
                  {
                    "text": "Which entry fits the specific process?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "mechanisms",
        "name": "Mechanisms",
        "description": "Mechanisms.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "signalling",
            "name": "Signalling",
            "description": "Signalling and genes.",
            "findings": [
              {
                "id": "signalling-finding",
                "name": "Signalling",
                "description": "Signalling.",
                "questions": [
                  {
                    "text": "How do signalling pathways, transcription factors and tissue interactions drive organ formation?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which references are standard?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          },
          {
            "id": "sex",
            "name": "Sex",
            "description": "Sex differentiation.",
            "findings": [
              {
                "id": "sex-finding",
                "name": "Sex",
                "description": "Sex.",
                "questions": [
                  {
                    "text": "How do male and female sex differentiation proceed from the bipotential gonad, in general terms?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which sources are cited?",
                    "kind": "provenance"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "timeline",
        "name": "Timeline",
        "description": "Timelines.",
        "rationale": "Science.",
        "layers": [
          {
            "id": "human",
            "name": "Human",
            "description": "Human development.",
            "findings": [
              {
                "id": "human-finding",
                "name": "Human",
                "description": "Human.",
                "questions": [
                  {
                    "text": "When do human organs form and mature, and why is the embryonic period sensitive?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits human embryonic development?",
                    "kind": "action"
                  }
                ]
              }
            ]
          },
          {
            "id": "plants",
            "name": "Plants",
            "description": "Plants.",
            "findings": [
              {
                "id": "plants-finding",
                "name": "Plants",
                "description": "Plants.",
                "questions": [
                  {
                    "text": "How do meristems produce leaves, roots and flowers throughout a plant s life?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits meristem?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      },
      {
        "id": "context",
        "name": "Context",
        "description": "Medicine and research.",
        "rationale": "Context.",
        "layers": [
          {
            "id": "medicine",
            "name": "Medicine",
            "description": "Birth defects and maturity.",
            "findings": [
              {
                "id": "medicine-finding",
                "name": "Medicine",
                "description": "Medicine.",
                "questions": [
                  {
                    "text": "How do disruptions cause birth defects, and why does fetal organ maturity matter in preterm birth, in general terms?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Is the user asking about a pregnancy, which needs a clinician?",
                    "kind": "boundary"
                  }
                ]
              }
            ]
          },
          {
            "id": "research",
            "name": "Research",
            "description": "Organoids and regeneration.",
            "findings": [
              {
                "id": "research-finding",
                "name": "Research",
                "description": "Research.",
                "questions": [
                  {
                    "text": "How do organoids and regenerative medicine build on organogenesis?",
                    "kind": "provenance"
                  },
                  {
                    "text": "Which entry fits organoid?",
                    "kind": "action"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  },
  "openQuestions": [
    "Should sex differentiation and plant organogenesis be separate primary entries?",
    "How should developmental biology sources be linked?",
    "The registry entry has merged aliases naming distinct processes; should they be split off?"
  ],
  "statistics": {
    "bundles": 4,
    "layers": 8,
    "findings": 8,
    "questions": 16
  }
}