Alzheimer's disease
Let an agent give accurate general information on Alzheimer's disease, recognise changes needing assessment, explain diagnosis, care and research with evidence, and point to specialist care and support for people and carers without individual medical advice.
Bundle → Layer → Finding → Questions Filled
4 bundles · 8 layers · 8 findings · 16 questions
Assess Changes to check.
Signs
Warning changes.
Signs
Warning changes.
- Are there progressive memory or thinking changes that affect daily life and warrant assessment? boundary
- Should the person see a doctor for evaluation, including of treatable causes? action
Urgent
Urgent situations.
Urgent
Urgent situations.
- Is there sudden confusion, a wandering person at risk or another emergency? boundary
- Which service should be contacted now? action
Understand The disease.
Mechanism
What happens in the brain.
Mechanism
Mechanism.
- What is known about the causes and brain changes of Alzheimer's disease, according to research? provenance
- Is the user asking about their own diagnosis or test results? boundary
Risk
Risk and genetics.
Risk
Risk.
- What do health authorities say about risk factors, protective factors and inherited forms? provenance
- Who is eligible for genetic counselling? provenance
Care Treatment and support.
Treatment
Care options.
Treatment
Care options.
- Which treatments and supportive care exist, in general terms, and what is the evidence for new disease-modifying therapies? provenance
- Which questions should be asked of the specialist? action
Unproven
Unproven treatments.
Unproven
Unproven treatments.
- Does this offered treatment or supplement have regulatory approval and evidence? boundary
- What do regulators warn about? provenance
Support People and carers.
Organisations
Support organisations.
Organisations
Support.
- Which organisations support people with Alzheimer's disease and their carers here? provenance
- Which planning tools, such as advance care planning, exist? provenance
Research
Research participation.
Research
Research.
- Which trials and registries are recruiting, according to registries? provenance
- How can someone discuss participation with their team? action
Classifiers Filled
- Family
- Thing Registry
- Category
- Cross-cutting context
- Entry kind
- thing
- Plane
- XCT
- Domain
- XCT.STA
- Other names and narrower kinds
- early-onset autosomal dominant Alzheimer disease, Alzheimer disease 16, Alzheimer disease 17, Alzheimer disease 18, Alzheimer disease 19, early-onset Alzheimer's disease, Alzheimer disease type 1, Alzheimer disease, susceptibility to, mitochondrial, Alzheimer disease without neurofibrillary tangles, Alzheimer's disease 1
What it is Filled
A progressive neurodegenerative disease and the most common cause of dementia, characterised by accumulation of amyloid plaques and tau tangles in the brain, leading to memory loss, cognitive decline and changes in behaviour, usually in older age but with rarer early-onset and inherited forms; it is diagnosed by clinical assessment, imaging and biomarkers, and managed with supportive care and, increasingly, disease-modifying therapies.
Why it exists Filled
Let an agent give accurate general information on Alzheimer's disease, recognise changes needing assessment, explain diagnosis, care and research with evidence, and point to specialist care and support for people and carers without individual medical advice.
Distinguishing features Filled
- Most common dementia
- Amyloid and tau pathology
- Progressive
- Late and early-onset forms
What robots and AI may and may not do Filled
Must not
- Diagnose Alzheimer's disease in a specific person.
- Promote unproven cures or supplements.
- Take advantage of a person's impaired memory or judgement, such as in finances or consent.
- Speak to or about people with dementia in ways that strip their dignity.
Only with a human decision
- Decisions on care, capacity, finances or living arrangements for a person with dementia.
May
- Explain Alzheimer's disease, its stages and care options from health authorities.
- Support people living with dementia and carers with reminders and information they have chosen.
Moral aspects Filled
- People with dementia are at high risk of abuse and exploitation.
- Dignity and the person's own wishes matter at every stage.
Who is affected
- People with dementia
- Family carers
- Care workers
Owners Filled
Steward
The person affected and their legal representatives; clinicians answer for diagnosis and care.
Links to other meta-models Filled
parent
- Q2397106 - registry parent class
- Q438962 - registry parent class
- neurodegeneration - neurodegenerative disease
related
- tauopathy - category
- aging-associated disease - category
- brain - organ
What else AI and robots need to interact with it Filled
Identity and identifiers required Filled
- Vercy registry: vr.tr.alzheimer-s-disease
- Wikidata: Q11081 (https://www.wikidata.org/wiki/Q11081)
Direct properties not applicable Not applicable
Not applicable
Plane XCT: no invented physical properties.
Recognition optional Filled
- Progressive memory loss and cognitive decline
- Amyloid and tau pathology
- Other dementias have different patterns and causes
- Not physical; progressive memory and cognitive changes.
Capabilities and actions required Filled
- explain the disease and its stages in general terms
- recognise changes needing assessment
- explain diagnosis, treatment and research
- find specialist services and carer support
Hazards and failure modes required Filled
- Missing treatable causes of cognitive change
- Agents diagnosing
- Unproven treatments and scams targeting people with dementia
Standards and interfaces required Filled
- Clinical guidelines from neurology and dementia bodies
- Medicines regulation for disease-modifying therapies
- Care standards and dementia strategies
Context of use required Filled
- A neurodegenerative disease requiring diagnosis, care and support.
- late-onset Alzheimer's disease
- early-onset Alzheimer's disease
- inherited autosomal dominant forms
- mixed dementia with vascular changes
- preclinical and prodromal stages
Sources Filled
- Wikidata item Q11081: Alzheimer's disease - identity and sense of the item
- Wikipedia: Alzheimer's disease - general description of the item
Open questions
- Should each form be a separate entry?
- How should guidelines be linked?
- How should support services be localised?
Machine files
Provenance
thing registry research (pass 2) · unreviewed
Built from: models/things/publications/thing-q11081/spec.json