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Research draft

onchocerciasis

vr.tr.onchocerciasis · XCT.STA

Let an agent explain onchocerciasis and its transmission, relay symptoms, treatment and control programmes from WHO and tropical medicine sources in general terms, describe the regional skin forms the registry aliases name, and distinguish onchocerciasis from other filarial diseases and from trachoma as a cause of blindness.

Thing Registry Cross-cutting context

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain onchocerciasis and its transmission, relay symptoms, treatment and control programmes from WHO and tropical medicine sources in general terms, describe the regional skin forms the registry aliases name, and distinguish onchocerciasis from other filarial diseases and from trachoma as a cause of blindness.

River blindness, a neglected tropical disease caused by the parasitic worm Onchocerca volvulus transmitted by blackflies breeding in fast-flowing rivers, causing severe itching, skin changes known regionally as sowda, mal morando and erisipela de la costa, nodules and, in ocular onchocerciasis, visual impairment and blindness; it affects mainly sub-Saharan Africa and is controlled by mass ivermectin treatment and vector control. The model gives general information and routes people to health services.

What it is for: Not applicable; a disease.

It can be explain the disease; relay treatment and control; route to health services; distinguish related diseases.

Distinguishing features

Filarial parasite

Blackfly vector

Skin and eye disease

Mass treatment control

What it looks like

Not a visible object; skin nodules, dermatitis and eye disease.

Physical character

people infected: about 21 million - 2017 estimate

vector: Simulium blackflies note

treatment: ivermectin mass drug administration note

countries verified free: Colombia, Ecuador, Mexico, Guatemala list - as of 2020s

How it is recognised

Parasitic disease transmitted by blackflies

Ocular onchocerciasis, sowda, mal morando, erisipela de la costa

Lymphatic filariasis is a different filarial disease; trachoma is bacterial

Related models

is a kind of - in registry terms

filariasis

is a kind of - in registry terms

neglected tropical disease

is caused by - a filarial worm

Onchocerca volvulus

is treated with - in mass programmes

ivermectin

In practice

Families and kinds

ocular onchocerciasis

onchocercal skin disease including sowda

regional forms such as mal morando and erisipela de la costa

nodding syndrome association under study

Identifiers

ICD-10 B73 onchocerciasis

MeSH D009855 Onchocerciasis

Standards and regulation

WHO elimination guidelines and verification criteria

National mass drug administration programmes

Failure modes and hazards

Agents giving personal medical advice

Ivermectin risks in areas with Loa loa co-infection

Registry aliases naming regional terms without context

Also called

ocular onchocerciasisMal morandoErisipela de la costaSowda

Where this came from

wikidata · CC0 1.0

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand What onchocerciasis is.

Clinical.

Definition

Definition.

Definition

Definition.

  1. What is onchocerciasis, and how does it differ from lymphatic filariasis and trachoma? definition
  2. Is the user describing personal symptoms, which need a health service? boundary

Forms

Forms.

Forms

Forms.

  1. What are ocular onchocerciasis, sowda, mal morando and erisipela de la costa? definition
  2. Which entry fits the specific form? action
Disease Transmission and disease.

Science.

Transmission

Transmission.

Transmission

Transmission.

  1. How do blackflies transmit the parasite, and what is its life cycle? provenance
  2. Which references are standard? provenance

Effects

Effects.

Effects

Effects.

  1. How does the parasite cause skin and eye disease? provenance
  2. Which sources are cited? provenance
Control Treatment and control.

Regulation.

Treatment

Treatment.

Treatment

Treatment.

  1. How is onchocerciasis treated with ivermectin and other drugs, in general terms, and what precautions apply? provenance
  2. Which entry fits ivermectin? action

Programmes

Programmes.

Programmes

Programmes.

  1. How have WHO and partner programmes controlled and eliminated the disease? provenance
  2. Which entry fits the specific programme? action
Context History and burden.

Context.

History

History.

History

History.

  1. How did the Onchocerciasis Control Programme and Mectizan donation change the disease? provenance
  2. Which entry fits the history of tropical medicine? action

Burden

Burden.

Burden

Burden.

  1. Where does the disease persist, and what is its social burden? provenance
  2. Which entry fits neglected tropical disease? action

What the second pass must settle

  • Should ocular onchocerciasis and sowda be separate primary entries?
  • How should WHO sources be linked?
  • The registry entry has merged aliases naming regional skin forms; should they be recorded as such?