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leiomyosarcoma

vr.tr.leiomyosarcoma · thing-q1504713

Let an agent explain leiomyosarcoma in general terms, relay sites, diagnosis, treatment approaches and research from oncology sources, route to specialist care, describe the named variants and flag the stage alias, and distinguish leiomyosarcoma from leiomyoma, gastrointestinal stromal tumour, other sarcomas and carcinomas, without diagnosing or advising individual treatment.

Thing Registry Cross-cutting context XCT.STA
Bundle → Layer → Finding → QuestionsClassifiersWhat it isWhy it existsDistinguishing featuresWhat robots and AI may and may not doMoral aspectsOwnersLinks to other meta-modelsIdentity and identifiersDirect propertiesRecognitionCapabilities and actionsHazards and failure modesStandards and interfacesContext of useSources

Bundle → Layer → Finding → Questions Filled

4 bundles · 8 layers · 8 findings · 16 questions

Understand What leiomyosarcoma is.

Definition

Definition.

Definition

Definition.

  1. What is leiomyosarcoma, and how does it differ from leiomyoma, GIST, other sarcomas and carcinomas? definition
  2. Does someone have a growing lump or a diagnosis, in which case a specialist sarcoma team should guide care? boundary

Variants

Named variants.

Variants

Variants.

  1. What are colon, fallopian tube, CNS, pulmonary artery and granular cell leiomyosarcomas, and what does metastatic mean? definition
  2. Which entry fits the specific variant? action
Clinical Diagnosis.

Diagnosis

Diagnosis.

Diagnosis

Diagnosis.

  1. How are imaging and biopsy used to diagnose leiomyosarcoma? provenance
  2. Which references are standard? provenance

Uterine

Uterine leiomyosarcoma.

Uterine

Uterine.

  1. Why can uterine leiomyosarcoma be hard to tell from fibroids before surgery? provenance
  2. Which sources are cited? provenance
Treatment Treatment approaches.

Approaches

Approaches.

Approaches

Approaches.

  1. What general approaches do sarcoma guidelines describe, with recommendations attributed? provenance
  2. Is the information current? boundary

Centres

Specialist centres.

Centres

Centres.

  1. Why do guidelines recommend treatment at sarcoma centres? provenance
  2. Which entry fits sarcoma? action
Context Research and support.

Research

Clinical trials.

Research

Research.

  1. What research directions are reported for leiomyosarcoma, checked against current sources? provenance
  2. Is the presentation neutral and attributed? boundary

Support

Patient support.

Support

Support.

  1. What do sarcoma patient organisations offer? provenance
  2. Which entry fits Sarcoma UK? action

Classifiers Filled

Family
Thing Registry
Category
Cross-cutting context
Entry kind
thing
Plane
XCT
Domain
XCT.STA
Other names and narrower kinds
leiomyosarcoma metastatic, granular cell leiomyosarcoma, fallopian tube leiomyosarcoma, central nervous system leiomyosarcoma, pulmonary artery leiomyosarcoma, colon leiomyosarcoma, mediastinum leiomyosarcoma, extrahepatic bile duct leiomyosarcoma, inflammatory leiomyosarcoma, conventional leiomyosarcoma, ovary leiomyosarcoma, epithelioid leiomyosarcoma

What it is Filled

A rare malignant tumour of smooth muscle cells, a type of soft tissue sarcoma that can arise in the uterus, retroperitoneum, blood vessel walls such as the inferior vena cava and pulmonary artery, skin and other sites, with site-based and histological variants the registry aliases name including colon, fallopian tube, central nervous system and pulmonary artery leiomyosarcomas, granular cell leiomyosarcoma and metastatic leiomyosarcoma, which is a disease stage rather than a kind; treatment is usually surgery, with chemotherapy or radiotherapy in some cases, planned by specialist sarcoma teams, and outcomes depend on site, grade and spread. People with a growing lump or unexplained symptoms should see a doctor, and specialist centres are recommended.

Why it exists Filled

Let an agent explain leiomyosarcoma in general terms, relay sites, diagnosis, treatment approaches and research from oncology sources, route to specialist care, describe the named variants and flag the stage alias, and distinguish leiomyosarcoma from leiomyoma, gastrointestinal stromal tumour, other sarcomas and carcinomas, without diagnosing or advising individual treatment.

Distinguishing features Filled

  • Smooth muscle origin
  • Many sites
  • Rare
  • Specialist multidisciplinary care

What robots and AI may and may not do Filled

Must not

  • Diagnose leiomyosarcoma or rule it out, including distinguishing it from a fibroid.
  • Recommend specific treatments, doses or trials for a particular patient.
  • Promote unproven cures or discourage evidence-based treatment.
  • State survival odds for an individual as if they were certain.

Only with a human decision

  • Any decision about surgery, chemotherapy or palliative care for a patient.
  • Breaking news of a sarcoma diagnosis or recurrence.

May

  • Explain what leiomyosarcoma is and where it can arise, in general terms.
  • Encourage people with suspected sarcoma to seek a specialist sarcoma centre.
  • Summarise guidance from named cancer bodies with dates.

Moral aspects Filled

  • Rare cancers are often diagnosed late, and misplaced reassurance can cost lives.
  • Patients facing a grave diagnosis are vulnerable to false hope and exploitation.

Who is affected

  • Patients and survivors
  • Families and carers
  • Specialist clinicians

Owners Filled

Steward

The treating oncology team answers for each patient; nobody owns the disease.

Master systems

  • Cancer registries

Links to other meta-models Filled

parent

  • Q18556240 - registry parent class

related

  • soft tissue sarcoma - related
  • leiomyoma
  • gastrointestinal stromal tumor
  • sarcoma surgery - approach

What else AI and robots need to interact with it Filled

Identity and identifiers required Filled

  • Vercy registry: vr.tr.leiomyosarcoma
  • Wikidata: Q1504713 (https://www.wikidata.org/wiki/Q1504713)

Direct properties not applicable Not applicable

  • soft tissue sarcomas: about 1 percent of adult cancers note - attributed
  • leiomyosarcoma share of soft tissue sarcomas: roughly 10-20 percent note - estimates vary
  • registry parent: smooth muscle cancer note

Plane XCT: no invented physical properties.

Recognition optional Filled

  • Malignant smooth muscle tumour
  • Metastatic leiomyosarcoma, granular cell leiomyosarcoma, fallopian tube leiomyosarcoma, central nervous system leiomyosarcoma, pulmonary artery leiomyosarcoma, colon leiomyosarcoma
  • Leiomyomas are benign; GISTs arise from interstitial cells; other sarcomas come from other connective tissues; carcinomas come from epithelium
  • A firm mass that may be found on imaging or as a lump; diagnosed by biopsy.

Capabilities and actions required Filled

  • explain sites and features
  • relay diagnosis and treatment approaches
  • describe named variants
  • route to specialist care

Hazards and failure modes required Filled

  • Delayed specialist referral
  • Misdiagnosis as fibroid
  • Stage alias treated as kind

Standards and interfaces required Filled

  • ESMO and NCCN sarcoma guidelines
  • WHO Classification of Soft Tissue and Bone Tumours

Context of use required Filled

  • Not applicable; a cancer.
  • uterine leiomyosarcoma
  • retroperitoneal leiomyosarcoma
  • vascular leiomyosarcoma
  • cutaneous leiomyosarcoma

Sources Filled

  1. Wikidata item Q1504713: leiomyosarcoma - identity and sense of the item
  2. Wikipedia: Leiomyosarcoma - general description of the item

Open questions

  • The registry alias metastatic leiomyosarcoma should be treated as a stage, not a kind
  • Should site variants be separate entries?
  • How should sarcoma guidelines be linked and kept current?

Machine files

Card as JSON Specification Card backlog vercy.card/1

Provenance

thing registry research (pass 2) · unreviewed

Built from: models/things/publications/thing-q1504713/spec.json