hyperaldosteronism
Let an agent explain hyperaldosteronism in general terms, relay primary and secondary forms, causes, diagnosis and treatment approaches from endocrinology sources, describe the named forms and flag the loosely filed Cushing aliases, route urgent symptoms, and distinguish hyperaldosteronism from Cushing syndrome, phaeochromocytoma, essential hypertension and Addison disease, without diagnosing individuals.
Bundle → Layer → Finding → Questions Filled
4 bundles · 8 layers · 8 findings · 16 questions
Understand What hyperaldosteronism is.
Definition
Definition.
Definition
Definition.
- Is there severe muscle weakness, paralysis, palpitations or very high blood pressure, in which case seek urgent medical care? boundary
- What is hyperaldosteronism, and how does it differ from Cushing syndrome, phaeochromocytoma, essential hypertension and Addison disease? definition
Forms
Named forms.
Forms
Forms.
- What are Conn syndrome, aldosterone-producing adenoma, bilateral hyperplasia and familial forms, and why are the Cushing aliases different? definition
- Which entry fits the specific form? action
Mechanism Mechanism.
Aldosterone
Aldosterone effects.
Aldosterone
Aldosterone.
- How does excess aldosterone raise blood pressure and lower potassium? provenance
- Which references are standard? provenance
Causes
Primary and secondary.
Causes
Causes.
- How do primary and secondary hyperaldosteronism differ in cause? provenance
- Which sources are cited? provenance
Clinical Diagnosis and treatment.
Diagnosis
Diagnosis.
Diagnosis
Diagnosis.
- How is primary aldosteronism screened for and confirmed? measurement
- Is the information current? boundary
Treatment
Treatment approaches.
Treatment
Treatment.
- What general treatment approaches such as surgery or aldosterone blockers do guidelines describe, with recommendations attributed? provenance
- Which entry fits spironolactone? action
Context Awareness.
Hypertension
Under-recognition.
Hypertension
Hypertension.
- Why do guidelines note primary aldosteronism as under-recognised in hypertension, with findings attributed? provenance
- Is the presentation neutral and attributed? boundary
Data quality
Misfiled aliases.
Data quality
Data quality.
- Why should Cushing syndrome aliases be separated from hyperaldosteronism? provenance
- Which entry fits Cushing syndrome? action
Classifiers Filled
- Family
- Thing Registry
- Category
- Cross-cutting context
- Entry kind
- thing
- Plane
- XCT
- Domain
- XCT.STA
- Other names and narrower kinds
- aldosterone-producing adrenal cortex adenoma, aldosterone-producing adenoma with seizures and neurological abnormalities, Cushing syndrome due to macronodular adrenal hyperplasia, ectopic Cushing syndrome, Familial hyperaldosteronism, Familial hyperaldosteronism type 2, familial hyperaldosteronism type 3, secondary hyperaldosteronism
What it is Filled
A group of conditions in which the adrenal glands produce too much of the hormone aldosterone, causing the body to retain sodium and lose potassium, leading to high blood pressure and sometimes low potassium; primary hyperaldosteronism, or Conn syndrome, arises from the adrenal glands themselves, often from an aldosterone-producing adenoma or bilateral hyperplasia, while secondary hyperaldosteronism responds to other causes, and familial forms exist, as registry aliases name. Some Cushing syndrome aliases listed involve cortisol excess rather than aldosterone and appear loosely filed. Primary hyperaldosteronism is an under-recognised cause of high blood pressure, and diagnosis and treatment belong to doctors; severe symptoms such as muscle weakness, paralysis or very high blood pressure need urgent care.
Why it exists Filled
Let an agent explain hyperaldosteronism in general terms, relay primary and secondary forms, causes, diagnosis and treatment approaches from endocrinology sources, describe the named forms and flag the loosely filed Cushing aliases, route urgent symptoms, and distinguish hyperaldosteronism from Cushing syndrome, phaeochromocytoma, essential hypertension and Addison disease, without diagnosing individuals.
Distinguishing features Filled
- Excess aldosterone
- Sodium retention and potassium loss
- Under-recognised hypertension cause
- Primary and secondary forms
What robots and AI may and may not do Filled
Must not
- Diagnose hyperaldosteronism from symptoms or a single test result.
- Advise stopping or changing blood pressure or potassium medicines.
- Confuse hyperaldosteronism with Cushing syndrome because of loosely filed aliases.
- Recommend potassium supplements in doses for a person.
Only with a human decision
- Any decision on testing, medication or adrenal surgery.
May
- Explain what hyperaldosteronism is and how primary and secondary forms differ.
- Suggest asking a clinician about screening for people with hard-to-control blood pressure.
Moral aspects Filled
- The condition is underdiagnosed; missed cases suffer avoidable strokes and heart damage.
- Self-treating low potassium can be dangerous.
Who is affected
- Patients with high blood pressure
- Their families
- Clinicians
Owners Filled
Steward
The person affected, with their clinical team; nobody owns the condition.
Links to other meta-models Filled
parent
- Q4684750 - registry parent class
related
- adrenal gland hyperfunction - in registry terms
- hypertension
- Cushing syndrome
- Addison s disease
What else AI and robots need to interact with it Filled
Identity and identifiers required Filled
- Vercy registry: vr.tr.hyperaldosteronism
- Wikidata: Q1640860 (https://www.wikidata.org/wiki/Q1640860)
Direct properties not applicable Not applicable
- primary form: Conn syndrome note
- effects: high blood pressure, low potassium list
- registry parent: adrenal gland hyperfunction note
Plane XCT: no invented physical properties.
Recognition optional Filled
- Excess aldosterone production
- Aldosterone-producing adenoma, familial hyperaldosteronism, familial hyperaldosteronism type 2, Cushing syndrome due to macronodular hyperplasia, ectopic Cushing syndrome, aldosterone-producing adenoma with seizures
- Cushing syndrome is cortisol excess; phaeochromocytoma is adrenaline-secreting; essential hypertension has no single cause; Addison disease is adrenal insufficiency
- Not visible; identified through blood pressure, blood tests and imaging.
Capabilities and actions required Filled
- explain forms and causes
- relay diagnosis and treatment approaches
- describe named forms
- route urgent symptoms
Hazards and failure modes required Filled
- Missed diagnosis in resistant hypertension
- Severe low potassium
- Loosely filed Cushing aliases
Standards and interfaces required Filled
- Endocrine Society guidelines on primary aldosteronism
Context of use required Filled
- Not applicable; a hormonal disorder.
- primary hyperaldosteronism or Conn syndrome
- aldosterone-producing adenoma
- bilateral adrenal hyperplasia
- familial hyperaldosteronism
- secondary hyperaldosteronism
Sources Filled
- Wikidata item Q1640860: hyperaldosteronism - identity and sense of the item
- Wikipedia: Hyperaldosteronism - general description of the item
Open questions
- The registry Cushing syndrome aliases should be moved to cortisol-excess entries
- Should familial forms be separate entries?
- How should guidelines be linked and kept current?
Machine files
Provenance
thing registry research (pass 2) · unreviewed
Built from: models/things/publications/thing-q1640860/spec.json