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Research draft

heredity

vr.tr.heredity · ACT.PRC

Let an agent explain heredity and inheritance patterns in general terms, point people to genetic counselling for personal questions, and reject misuse of heredity for eugenic or discriminatory claims.

Thing Registry Activities and processes

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain heredity and inheritance patterns in general terms, point people to genetic counselling for personal questions, and reject misuse of heredity for eugenic or discriminatory claims.

The passing of genetic traits from parents to offspring through genes, following patterns such as autosomal dominant, autosomal recessive, X-linked, codominant, polygenic and multifactorial inheritance, and interacting with environment and, in some cases, epigenetic effects.

What it is for: Genetics, medicine, breeding and evolution.

It can be explain inheritance patterns with examples; calculate simple Mendelian probabilities; find genetic counselling services; understand genes and environment together.

Distinguishing features

Transmission through genes

Several inheritance patterns

Probabilistic

Interacts with environment

What it looks like

Not visible directly; seen in family resemblances, pedigrees and genetic tests.

How it is recognised

Pedigree charts

Punnett squares

Learned behaviour is not genetic inheritance

Related models

is a kind of - category

evolutionary process

is carried by - unit

gene

is studied by - field

genetics

is related to - kinship

descent-relation

In practice

Families and kinds

Mendelian inheritance

X-linked and mitochondrial inheritance

codominance and incomplete dominance

polygenic and multifactorial inheritance

epigenetic inheritance (debated scope)

Standards and regulation

Genetic testing and counselling standards

Laws against genetic discrimination

Oviedo Convention on human rights and biomedicine

Failure modes and hazards

Genetic determinism and eugenic claims

Agents interpreting personal genetic risk

Over-interpreting consumer tests

Also called

Mendelian inheritanceautosomal dominantcodominantautosomal recessiveX-linked recessiveoligogenic inheritancepaternal inheritancematernal inheritancemtDNA transmissionX-linked dominantinheritance patternuniparental inheritancegenetic linkageadenylosuccinase lyase deficiency

Where this came from

wikidata · CC0 1.0

Also registered as vr.tr.heredity-attribute

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Patterns Inheritance patterns.

Patterns guide expectations.

Mendelian

Dominant and recessive.

Mendelian

Mendelian patterns.

  1. Does this trait follow a dominant, recessive or X-linked pattern? definition
  2. What are the probabilities for offspring in a textbook example? measurement

Complex

Polygenic traits.

Complex

Complex traits.

  1. Is the trait polygenic or multifactorial, with environmental influence? definition
  2. What does heritability mean and not mean? boundary
Personal Family questions.

Counselling helps.

Counselling

Genetic counselling.

Counselling

Genetic counselling.

  1. Is the user asking about a condition in their own family or pregnancy? boundary
  2. How can they access genetic counselling? action

Tests

Genetic tests.

Tests

Genetic tests.

  1. What can clinical and consumer genetic tests tell and not tell? boundary
  2. Which privacy issues arise? boundary
Science Genetics.

Mechanisms explain heredity.

Genes

DNA and chromosomes.

Genes

Genes.

  1. How are genes passed on through meiosis and fertilisation? definition
  2. What role do chromosomes play? definition

Epigenetics

Beyond DNA sequence.

Epigenetics

Epigenetics.

  1. What evidence exists for transgenerational epigenetic inheritance in humans? provenance
  2. How strong is it? boundary
Ethics Misuse.

Heredity has been misused.

Eugenics

Historical misuse.

Eugenics

Eugenics.

  1. How was heredity misused in eugenics, according to historians? provenance
  2. How should the agent reject claims ranking groups by heredity? action

Discrimination

Genetic discrimination.

Discrimination

Genetic discrimination.

  1. Which laws protect people from genetic discrimination here? provenance
  2. Where can concerns be raised? action

What the second pass must settle

  • Should inheritance patterns be separate entries?
  • How should genetic counselling services be linked?
  • How should epigenetic claims be framed?