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Research draft

vitamin deficiency

vr.tr.vitamin-deficiency · XCT.STA

Let an agent explain vitamin deficiencies in general terms, relay symptoms, causes and public health measures from clinical and public health sources, distinguish dietary from inherited and malabsorptive forms, and route personal questions to clinicians.

Thing Registry Cross-cutting context

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain vitamin deficiencies in general terms, relay symptoms, causes and public health measures from clinical and public health sources, distinguish dietary from inherited and malabsorptive forms, and route personal questions to clinicians.

A nutritional disorder caused by insufficient intake, absorption or metabolism of one or more vitamins, producing conditions such as scurvy from vitamin C deficiency, rickets and osteomalacia from vitamin D, beriberi from thiamine, pellagra from niacin, pernicious anaemia from vitamin B12 and night blindness from vitamin A; deficiencies arise from poor diet, malabsorption, increased needs, inherited metabolic disorders and some medicines, and are diagnosed and treated clinically.

What it is for: Not applicable; a category of disease.

It can be explain kinds and causes in general terms; relay recognised signs and risk groups; relay public health measures such as fortification; route personal diagnosis and supplementation to clinicians.

Distinguishing features

Specific to each vitamin

Dietary, malabsorptive or inherited causes

Often reversible with treatment

Public health prevention by fortification

What it looks like

Not a visible object; presentations range from fatigue and skin changes to bone deformity and neurological signs.

How it is recognised

Disease from lack of a specific vitamin

Named syndromes per vitamin

Mineral deficiencies and protein-energy malnutrition are separate categories

Related models

is a kind of - the category

nutritional deficiency disease

is a kind of - the broader group

nutrition disorder

is prevented by - a public health measure

food fortification

is confused with - a separate category

mineral deficiency

In practice

Families and kinds

scurvy, rickets, beriberi, pellagra and pernicious anaemia

vitamin A deficiency and night blindness

folate and B6 deficiencies

vitamin K deficiency, including in newborns and in animals

inherited vitamin metabolism disorders such as familial isolated vitamin E deficiency

deficiencies in animals as a veterinary category

Identifiers

ICD-10 E50-E56 vitamin deficiencies

ICD-11 5B55-5B5K vitamin deficiencies

Standards and regulation

Dietary reference intakes from national bodies

WHO guidance on micronutrient deficiencies

Food fortification regulations

Supplement labelling rules

Failure modes and hazards

Missed diagnosis in at-risk groups

Harm from excessive supplementation

Agents giving personal supplementation advice

Also called

familial isolated deficiency of vitamin Epyridoxine deficiency anemiavitamin K deficiency in birdsvitamin metabolic disorderbiotin deficiencyChlorosisascorbic acid deficiencyvitamin B deficiencyhypovitaminosisvitamin A deficiencyvitamin K deficiencyniacin deficiencypyridoxine deficiencyvitamin E deficiencypantothenic acid deficiencyphrynodermavitamin A deficiency with conjunctival xerosisobsolete vitamin A deficiency with corneal xerosisvitamin A deficiency with xerophthalmic corneal scarhereditary hypercarotenemia and vitamin A deficiency

Where this came from

wikidata · CC0 1.0

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand What vitamin deficiencies are.

General information.

Definition

Definition and kinds.

Definition

Definition.

  1. What vitamin deficiencies exist, and which diseases do they cause? definition
  2. Is the user asking about their own symptoms or supplements, which needs a clinician? boundary

Causes

Causes.

Causes

Causes.

  1. What causes deficiencies, from diet and malabsorption to inherited disorders and medicines? definition
  2. Which entry fits a specific deficiency disease? action
Clinical Recognition and treatment.

Clinical.

Signs

Signs and risk groups.

Signs

Signs.

  1. What signs and risk groups do clinical sources describe for each deficiency? provenance
  2. Is the presentation free of personal medical advice? boundary

Treatment

Diagnosis and treatment.

Treatment

Treatment.

  1. How are deficiencies diagnosed and treated, in general terms? provenance
  2. Which references are standard? provenance
Public health Prevention.

Public health.

Burden

Global burden.

Burden

Burden.

  1. What do WHO and studies report about the prevalence of deficiencies worldwide, with sources? measurement
  2. Which sources are cited? provenance

Prevention

Fortification and programmes.

Prevention

Prevention.

  1. What fortification and supplementation programmes exist, and what evidence supports them? provenance
  2. Which entry fits food fortification? action
Context History and animals.

Context.

History

History of discovery.

History

History.

  1. How were vitamins and deficiency diseases discovered, from scurvy to beriberi? provenance
  2. Which entry fits the history of nutrition? action

Animals

Veterinary deficiencies.

Animals

Animals.

  1. How do vitamin deficiencies affect livestock, poultry and pets, per veterinary sources? provenance
  2. Which entry fits animal nutrition? action

What the second pass must settle

  • Should each named deficiency disease be a separate entry?
  • How should reference intakes be linked by country?
  • The registry entry has merged aliases for rare inherited disorders and animal deficiencies; should they be split off?