m-chlorophenylpiperazine
Enable an agent to identify m-chlorophenylpiperazine, assess the form and quality of a particular sample, and determine evidence-supported handling, analytical and research actions.
Bundle → Layer → Finding → Questions Filled
6 bundles · 11 layers · 18 findings · 28 questions
mCPP identity and boundaries Establish the exact chemical entity represented by the registry name.
Molecular connectivity
Resolve the structure behind the substance name.
Meta-isomer resolution
Require structure-level evidence that resolves the chlorine position and piperazine attachment.
- Does the recorded structure place chlorine at phenyl position 3 relative to the nitrogen-linked piperazine group? definition
- Which authoritative identifier or authenticated standard resolves this sample as mCPP rather than an ortho or para isomer? provenance
Parent and related forms
Separate the parent identity from salts and preparations.
Form-specific identity
Record counterions and solvation explicitly while retaining the relationship to the mCPP parent.
- Is the material the free base, an identified salt or a preparation whose chemical form remains unresolved? definition
- Does the registry represent this salt separately, and which identifiers belong to the supplied form rather than the parent? boundary
mCPP sample and analysis Connect chemical identity to measured content in a particular sample.
Identification evidence
Evaluate analytical specificity and reference provenance.
Isomer-discriminating confirmation
Require evidence that the analytical method distinguishes relevant chlorophenylpiperazine alternatives.
- Which measurements distinguish mCPP from other chlorophenylpiperazine isomers in this matrix? measurement
- What reference-material identity, lot and supporting documentation anchor the assignment? provenance
Content and matrix
Represent the amount of mCPP and the substances accompanying it.
Quantitative basis
Distinguish assay, concentration and chromatographic response, including their uncertainty and mass basis.
- What mCPP content was measured, with which units, calibration, uncertainty and free-base or salt basis? measurement
- Which positional isomers, residual solvents or other constituents could affect identification or intended use? measurement
mCPP physical state and stability Describe form-dependent properties and changes during storage or preparation.
Conditional physical properties
Attach phase, transition and solution measurements to their experimental conditions.
Form-matched properties
Retain uncertainty when a reported value lacks material-form or method information.
- Which phase and melting, boiling or decomposition measurements apply to this exact mCPP form, at what pressure and purity? measurement
- What measured solubility or ionization data apply at the intended solvent composition, pH and temperature? measurement
Storage and change
Track whether a sample remains suitable over time.
Stability-supported use
Base storage and retest decisions on evidence for the supplied material or solution.
- What stability evidence supports the stated storage conditions and expiry or retest interval for this form? provenance
- Do storage excursions, appearance changes or assay drift require reanalysis before further use? action
mCPP biological interpretation Separate measured biological activity from conclusions about origin and exposure.
Activity context
Bind pharmacological statements to particular experimental systems.
Endpoint-specific activity
Record target-level and organism-level evidence separately rather than treating serotonergic activity as one universal effect.
- Which receptor or transporter endpoint was measured, in which species and assay system, at what concentration? measurement
- Does the evidence demonstrate binding, functional activation, inhibition or an organism-level response? boundary
Metabolic origin
Interpret occurrence in relation to possible precursor medicines and sample timing.
Detection versus origin
Keep detection separate from attribution to direct exposure or metabolic formation.
- What precursor-drug, co-metabolite and collection-time evidence accompanies the mCPP result? provenance
- Can the available evidence distinguish metabolic formation from direct exposure, or must origin remain unresolved? boundary
mCPP hazards and permitted actions Support handling and use decisions for the identified material in a specified jurisdiction.
Material-specific hazards
Resolve safety information for the actual form, concentration and solvent.
Applicable hazard evidence
Use attributable hazard information without assigning unsupported classifications or exposure thresholds.
- Which current safety data and GHS classifications explicitly cover this mCPP form and preparation? provenance
- Which documented controls apply to the proposed operation, and is a substance-specific exposure limit established or unlocated? action
Jurisdiction and purpose
Evaluate permissions against current rules and the intended operation.
Dated action authorization
Record the authority and scope of restrictions without extrapolating from another country or historical report.
- Which current rules cover mCPP, its salts and the proposed activity in the relevant jurisdiction? provenance
- What authorization or documented conditions, if any, must be satisfied before acquisition, transfer, research use or disposal? action
Evidence and external alignment What the world already says about this thing, gathered so the model can be checked against it.
Reported evidence
Findings from the breadth pass, kept separate from the structural claims.
Check these first
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these check these first hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Kinds and varieties
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these kinds and varieties hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Identifiers and schemes
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these identifiers and schemes hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Real-world use
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these real-world use hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Typical measurements
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these typical measurements hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Failure modes and hazards
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these failure modes and hazards hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Regional variation
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these regional variation hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Neighbouring kinds and how to tell them apart
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these neighbouring kinds and how to tell them apart hold for the sense of m-chlorophenylpiperazine this model covers, and on what evidence? provenance
Classifiers Filled
- Family
- Thing Registry
- Category
- Physical world and living systems
- Entry kind
- thing
- Plane
- PHY
- Domain
- PHY.MAT
What it is Filled
m-Chlorophenylpiperazine (mCPP) is a synthetic arylpiperazine, specifically 1-(3-chlorophenyl)piperazine, that acts at several serotonin receptor subtypes and is also formed as a metabolite of trazodone and nefazodone.
In scope
- Molecular identity, synonyms and differentiation from other chlorophenylpiperazine isomers
- Free-base identity and explicit relationships to protonated, salt and solvated forms
- Sample composition, purity, concentration and analytical identification
- Physical properties, stability and storage conditions for the specified material form
- Biological activity, metabolic provenance and limits of exposure interpretation
- Form-specific hazards and jurisdiction-specific restrictions on intended actions
Out of scope
- Finished tablets, mixtures and commercial products containing mCPP
- Complete models of trazodone and other precursor medicines
- Manufacturing routes and synthesis procedures
- Clinical diagnosis, prescribing and human dosing protocols
- Complete serotonin receptor and metabolic enzyme models
- General laboratory operations and waste-management systems
Why it exists Filled
Enable an agent to identify m-chlorophenylpiperazine, assess the form and quality of a particular sample, and determine evidence-supported handling, analytical and research actions.
Distinguishing features Filled
- The phenyl-ring chlorine occupies the meta, or 3-, position relative to the piperazine attachment; ortho and para chlorophenylpiperazines require separate identification.
- The defining connectivity is 1-(3-chlorophenyl)piperazine, with the aryl group attached to a piperazine nitrogen. The free base has formula C10H13ClN2, CAS 6640-24-0 and PubChem CID 1355. [PubChem identity record](https://pubchem.ncbi.nlm.nih.gov/compound/1355)
- The abbreviation mCPP must resolve to meta-chlorophenylpiperazine rather than being interpreted as a methyl-substituted chlorophenylpiperazine.
- The hydrochloride is a related material form with its own composition and identifier, rather than an interchangeable free-base mass standard. [PubChem monohydrochloride record](https://pubchem.ncbi.nlm.nih.gov/compound/25681)
- Detection of mCPP does not alone establish direct consumption because it can occur as a trazodone metabolite. [PubChem biological-role description](https://pubchem.ncbi.nlm.nih.gov/compound/1355)
What robots and AI may and may not do Filled
Must not
- Assist in making, obtaining, dosing or using it recreationally.
- Help pass it off as another drug or hide it in pills sold to people.
- Present it as a safe alternative to other drugs.
Only with a human decision
- Interpreting a drug test result that detects it in a named person.
May
- Describe mCPP, its pharmacology and its role as a drug metabolite from scientific sources.
- Report its legal status as stated in the relevant jurisdiction's law.
Moral aspects Filled
- It has been sold disguised as other drugs, exposing people to effects they did not choose.
- A positive test can come from prescribed medicines, so results can wrong people.
Who is affected
- People who use drugs
- Patients taking medicines that produce it
- People tested for drugs
Owners Filled
Steward
Nobody owns the compound; drug control and medicines authorities regulate it.
Links to other meta-models Filled
parent
- Q193430 - registry parent class
What else AI and robots need to interact with it Filled
Identity and identifiers required Filled
- Vercy registry: vr.tr.m-chlorophenylpiperazine
- Wikidata: Q286112 (https://www.wikidata.org/wiki/Q286112)
Direct properties required Filled
- Structural identity: 1-(3-chlorophenyl)piperazine; structure identifier and source
- Material form: Free base, identified salt, solvate, solution or unresolved form
- Molar mass: g/mol; free base 196.67, with separate values for identified salts
- Assay and impurity profile: Mass fraction or molar fraction; analytical area percentage recorded separately
- Solution concentration: mol/L or mg/mL; solvent and free-base-equivalent versus salt-mass basis
- Physical state and transition data: Observed phase; temperature in °C; pressure in kPa; melting, boiling or decomposition event
- Solubility and ionization: Solubility in g/L or mol/L; pKa; solvent, pH, temperature and method
- Analytical identification confidence: Unconfirmed, presumptive, confirmed or conflicting; methods and reference material
- Biological activity evidence: Target, species, assay, endpoint, concentration and supporting study
- Occurrence and metabolic provenance: Sample matrix, collection time, precursor-drug evidence and provenance confidence
- Hazard and regulatory status: Classification, material form, jurisdiction, intended action, authority and effective date
Recognition required Filled
- Not reliably identifiable by sight; confirmed only by laboratory analysis.
Capabilities and actions required Filled
- Resolve an mCPP label against structural identifiers and flag positional-isomer ambiguity.
- Compare a sample with an authenticated reference and record the strength of identification.
- Calculate substance amount or free-base-equivalent concentration from verified form and assay.
- Assess whether storage history and analytical quality support an intended laboratory use.
- Interpret detection alongside precursor-drug and sample-matrix evidence.
- Check whether a proposed acquisition, transfer, analysis or disposal is supported by current local requirements.
Hazards and failure modes required Filled
- Can cause anxiety, headache and other unpleasant effects.
- Adulterated pills expose people to unknown substances.
Standards and interfaces required Filled
- The Globally Harmonized System of Classification and Labelling of Chemicals, issued by the United Nations, provides the framework for chemical hazard communication where adopted into applicable law.
Context of use required Filled
- The compound is encountered in serotonin receptor research and in studies of drug metabolism.
- Analytical laboratories may examine it in reference materials or biological samples when investigating exposure to the compound or medicines that produce it as a metabolite.
Sources Filled
- Wikidata item Q286112: m-chlorophenylpiperazine - identity and sense of the item
- Wikipedia: Meta-Chlorophenylpiperazine - general description of the item
Open questions
- Does the registry intend this entry to cover only the parent compound, or also particular salts, and does an existing Vercy world model already own that scope?
- Which EC identifiers, form-specific physical constants, solubility values and stability limits can be supported by sources that identify material form and measurement conditions?
- Which current GHS classifications and occupational exposure limits, if any, apply to the free base and the particular salts or solutions encountered?
- Which validated analytical methods resolve the meta isomer and quantify it reliably in the intended matrices?
- Which target-specific biological findings and current jurisdictional restrictions are sufficiently supported for the intended research or handling decisions?
Machine files
Provenance
thing registry research (pass 2) · unreviewed
Built from: models/things/publications/thing-q286112/spec.json