kavain
Enable an agent to recognise kavain, assess the identity and condition of a particular sample, and determine its suitability for an intended use from documented evidence.
Bundle → Layer → Finding → Questions Filled
5 bundles · 9 layers · 15 findings · 23 questions
Kavain identity and registry boundary Defines which molecular and stereochemical material a kavain record represents.
Molecular recognition
Connects the registered name to a verifiable chemical structure.
Structure-backed identifiers
PubChem associates (+)-kavain with CID 5281565, CAS 500-64-1 and EC 207-907-2; use these as sourced mappings for that represented form, subject to registry boundary review. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/Kavain)
- Which structure and stereochemical specification does vr.tr.kavain intend to cover? definition
- Does each proposed external identifier resolve to that same represented form? provenance
Stereochemical boundary
Preserves differences between a specified enantiomer, racemic material and unresolved samples within the registered entry.
Form requires independent evidence
Represent stereochemical form explicitly without creating additional registry entries or inferring configuration from a supplier's use of kavain or kawain.
- Is this sample a specified enantiomer, a racemate or material with unmeasured enantiomeric composition? boundary
- What chiral analysis or traceable reference establishes its stereochemical assignment? measurement
Kavain composition and authentication Establishes what a sample contains and how its kavain identity was demonstrated.
Sample composition
Separates kavain content from matrix components and impurities.
Kavain-specific content
Record a kavain-specific assay with its calculation basis and separately quantify relevant related compounds, water and residual solvents.
- What is the kavain mass fraction, and is the result an absolute assay or chromatographic area percentage? measurement
- Which accompanying kavalactones or other impurities were measured, and with what detection limits? measurement
Authentication evidence
Links analytical conclusions to methods, standards and the actual sample tested.
Discriminating analytical confirmation
Use complementary evidence appropriate to the claim, such as structure-sensitive spectra, selective chromatography and chiral analysis; retention time alone needs supporting specificity evidence.
- How does the method distinguish kavain from dihydrokavain and other compounds expected in this sample? measurement
- Which reference material, lot and raw analytical records support the reported identity and assay? provenance
Kavain physical state and stability Connects measured material properties to preparation, storage and current sample condition.
Phase and solution behaviour
Records solid-state observations and solvent-dependent preparation limits.
Condition-qualified properties
Capture measured melting behaviour, solubility and thermal observations with form, purity and experimental conditions; leave unverified constants unresolved.
- What melting range or thermal transition was measured for this kavain form and purity? measurement
- At the proposed solvent composition and temperature, what dissolved kavain concentration is experimentally supported? measurement
Sample aging
Evaluates whether stored solids or prepared solutions retain their specified composition.
Supported holding conditions
Treat storage recommendations and solution holding times as evidence-dependent limits, with sample history and retest results available for assessment.
- What data support the stated container, temperature, light exposure and holding time for this presentation? provenance
- After a storage excursion or observed change, which kavain assay and impurity checks are required before reuse? action
Kavain evidence and use constraints Bounds the conclusions and actions supported for a particular kavain material.
Biological evidence boundary
Keeps substance-level experimental observations tied to their tested material and conditions.
Tested-material attribution
Any biological claim attached to kavain should identify the tested form, purity, concentration, vehicle and experimental system, and distinguish purified substance evidence from mixture evidence.
- Was the reported result obtained with authenticated kavain, a stereochemically specified sample or a kava mixture? boundary
- Which experimental conditions and material records limit transfer of that result to this sample? provenance
Handling and use eligibility
Relates the identified material to applicable safety documentation and intended-use requirements.
Documented use decision
Assess handling and use against current documents for the relevant chemical form, composition and jurisdiction; record unresolved classifications and exposure limits explicitly.
- Which current safety data sheet and authoritative classifications apply to this kavain form or solution? provenance
- Do this lot's identity, grade and documentation satisfy the requirements of the proposed use? action
Evidence and external alignment What the world already says about this thing, gathered so the model can be checked against it.
Reported evidence
Findings from the breadth pass, kept separate from the structural claims.
Check these first
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these check these first hold for the sense of kavain this model covers, and on what evidence? provenance
Kinds and varieties
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these kinds and varieties hold for the sense of kavain this model covers, and on what evidence? provenance
Identifiers and schemes
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these identifiers and schemes hold for the sense of kavain this model covers, and on what evidence? provenance
Real-world use
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these real-world use hold for the sense of kavain this model covers, and on what evidence? provenance
Typical measurements
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these typical measurements hold for the sense of kavain this model covers, and on what evidence? provenance
Failure modes and hazards
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these failure modes and hazards hold for the sense of kavain this model covers, and on what evidence? provenance
Neighbouring kinds and how to tell them apart
Recalled without web access and unsourced; every item is a lead to verify.
- Which of these neighbouring kinds and how to tell them apart hold for the sense of kavain this model covers, and on what evidence? provenance
Classifiers Filled
- Family
- Thing Registry
- Category
- Physical world and living systems
- Entry kind
- thing
- Plane
- PHY
- Domain
- PHY.MAT
What it is Filled
Kavain is a kavalactone found in kava (Piper methysticum), with molecular formula C14H14O3, and is one of the constituents studied for the plant's central nervous system activity.
In scope
- Kavain molecular identity and explicitly specified stereochemical form
- Sample purity, kavain content and accompanying kavalactones or other impurities
- Physical properties, phase and stability under recorded conditions
- Analytical confirmation and traceability of kavain samples and reference materials
- Evidence supporting handling restrictions and suitability for a stated use
Out of scope
- Piper methysticum cultivation, taxonomy and whole-plant characteristics
- Kava beverages, extracts and supplements as finished products
- Other kavalactones and kavain metabolites as independently identified substances
- Extraction or synthesis processes as complete operational models
- Clinical treatment decisions and efficacy claims for kava products
Why it exists Filled
Enable an agent to recognise kavain, assess the identity and condition of a particular sample, and determine its suitability for an intended use from documented evidence.
Distinguishing features Filled
- Confirm the molecular structure rather than matching the word kavain: the (+)-kavain record specifies C14H14O3 and a molar mass of 230.26 g/mol. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/Kavain)
- Resolve enantiomeric composition explicitly; an achiral identity assay cannot establish whether material is a specified enantiomer or a racemate.
- Differentiate kavain from dihydrokavain by structure and validated analytical evidence; dihydrokavain has formula C14H16O3. [PubChem](https://pubchem.ncbi.nlm.nih.gov/compound/10220256)
- Distinguish a kavain substance sample from a kava extract by recording the full sample matrix and quantified kavain content.
- Require chromatographic discrimination from neighbouring kavalactones instead of treating a total-kavalactone result as a kavain-specific measurement.
What robots and AI may and may not do Filled
Must not
- Recommend kavain or kava extracts to treat anxiety or other conditions in place of a clinician.
- Encourage combining kava products with alcohol or sedative medicines.
- Present kavain as proven safe for the liver.
- Help evade import or sale restrictions on kava products.
Only with a human decision
- Using kava products for a person with liver disease or on interacting medicines.
May
- Explain kavain as a kavalactone found in kava and summarize research on it with sources.
- Report regulatory status of kava products in a jurisdiction from official sources.
Moral aspects Filled
- Kava has deep cultural meaning in Pacific Island communities, beyond its chemistry.
- Health claims for psychoactive plant compounds can mislead vulnerable people.
Who is affected
- Consumers of kava products
- Pacific Island communities
- People with liver disease
Owners Filled
Steward
The laboratory or business that holds it; chemical safety authorities regulate supply and use.
Links to other meta-models Filled
parent
- Q408171 - registry parent class
What else AI and robots need to interact with it Filled
Identity and identifiers required Filled
- Vercy registry: vr.tr.kavain
- Wikidata: Q3194310 (https://www.wikidata.org/wiki/Q3194310)
Direct properties required Filled
- Structure and stereochemical identity: Structure identifier with absolute configuration and alkene geometry; stereochemistry unspecified when unresolved
- External identity mappings: CAS, PubChem CID, EC and other identifiers, each linked to its source and represented structure
- Kavain assay: % mass fraction or mg/g, with method, uncertainty and as-received or dry basis
- Enantiomeric composition: Enantiomer ratio or enantiomeric excess %, with chiral method and assignment evidence
- Impurity profile: Individual related compounds, residual solvents and water in %, mg/kg or another stated unit; detection limits recorded
- Material presentation: Solid, solution or other observed state; solvent and concentration where applicable
- Physical property evidence: Melting range in °C, solubility in g/L or mol/L, and thermal data with pressure, solvent, method and stereochemical form
- Storage and stability status: Within supported conditions, excursion recorded, retest required or degraded; linked dates and analytical evidence
- Use and handling constraints: Applicable safety documents, hazard classifications, exposure limits if established, jurisdiction, intended use and effective date
Recognition required Filled
- Identified by container label, chemical name and identifier, and certificate of analysis rather than by appearance alone.
Capabilities and actions required Filled
- Match a candidate kavain record to a structure and flag unresolved stereochemistry.
- Compare a sample with a kavain specification using assay, chiral composition and impurity evidence.
- Select analytical checks that distinguish kavain from accompanying kavalactones.
- Assess whether a proposed solvent and concentration are supported by solubility and stability evidence.
- Flag a stored sample for retesting after an excursion or unsupported holding period.
- Determine whether available documentation supports the intended use or leaves a decision unresolved.
Hazards and failure modes required Filled
- Sedation and impaired driving.
- Possible liver injury reported with some kava products.
- Interactions with alcohol and sedatives.
Standards and interfaces required Filled
- The Globally Harmonized System of Classification and Labelling of Chemicals, issued by the United Nations, provides the framework for assessing and communicating hazards of kavain supplied as a chemical.
Context of use required Filled
- Kavain is encountered in chemical studies of kava, analytical reference materials and laboratory investigations of kavalactones.
- It is used to investigate chemical composition and biological activity, with sample identity and purity affecting interpretation.
Sources Filled
- Wikidata item Q3194310: kavain - identity and sense of the item
- Wikipedia: Kavain - general description of the item
Open questions
- Does vr.tr.kavain encompass all stereochemical forms, or is its intended referent specifically (+)-kavain?
- Which experimentally measured melting, solubility and thermal data are reliable for each relevant stereochemical form and purity?
- Which validated methods adequately resolve kavain from likely co-occurring kavalactones, stereochemical variants and degradation products?
- What stability studies justify solid storage conditions, solution holding times and retest intervals?
- Which current hazard classifications, exposure limits if any, and intended-use restrictions apply to the exact kavain material in each relevant jurisdiction?
Machine files
Provenance
thing registry research (pass 2) · unreviewed
Built from: models/things/publications/thing-q3194310/spec.json