kidney cancer
Let an agent explain kidney cancer and its types in general terms from oncology guidelines, describe risk factors, diagnosis and treatment approaches, distinguish adult and childhood forms, and route personal questions to clinicians.
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain kidney cancer and its types in general terms from oncology guidelines, describe risk factors, diagnosis and treatment approaches, distinguish adult and childhood forms, and route personal questions to clinicians.
Cancer arising in the kidney, chiefly renal cell carcinoma in adults, urothelial carcinoma of the renal pelvis, and in children Wilms tumour and rarer tumours such as mesoblastic nephroma and malignant cystic nephroma, with uncommon forms such as small cell carcinoma and catecholamine-producing tumours of adjacent adrenal tissue sometimes grouped with them; kidney cancer is often found incidentally on imaging, is treated by surgery, targeted therapy and immunotherapy, and has risk factors including smoking, obesity and hypertension.
What it is for: Not applicable; a group of cancers.
It can be explain types and risk factors; relay diagnosis and treatment approaches; distinguish adult and childhood forms; route personal questions.
Distinguishing features
Renal cell carcinoma dominance
Incidental detection
Surgery as main treatment
Distinct childhood tumours
What it looks like
Not a visible object; a tumour seen on imaging.
Physical character
new cases worldwide: about 430000 per year - GLOBOCAN 2022
renal cell carcinoma share: about 90 percent - of adult kidney cancers
How it is recognised
Malignant tumours of the kidney
Renal cell carcinoma, renal pelvis cancer, Wilms tumour and rare types
Benign kidney tumours and cysts are not cancer; bladder cancer is a separate urinary cancer
Related models
is a kind of - in registry terms
is a kind of - in registry terms
is treated by - among other treatments
is contrasted with - such as oncocytoma
In practice
Families and kinds
renal cell carcinoma and its subtypes
urothelial carcinoma of the renal pelvis
Wilms tumour and other childhood kidney neoplasms
rare tumours such as mesoblastic nephroma, malignant cystic nephroma and small cell carcinoma
hereditary kidney cancer syndromes
Identifiers
ICD-11 2C90 malignant neoplasms of kidney
MeSH D007680 kidney neoplasms
Standards and regulation
Oncology guidelines from ESMO, NCCN and urological associations
Cancer registration standards
Drug approvals for targeted and immunotherapies
Failure modes and hazards
Late diagnosis
Agents giving personal medical advice
Confusing kidney cancer types
Overtreatment of small incidental masses
Also called
Where this came from
wikidata · CC0 1.0
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Help Getting help first.
Safety.
Signs
Warning signs.
Signs
Signs.
- What signs such as blood in the urine or flank pain need prompt assessment? action
- Is the user describing such signs, which need a clinician promptly? boundary
Care
Specialist care.
Care
Care.
- How is kidney cancer diagnosed and staged by specialists, in general terms? provenance
- Is the user asking about their own diagnosis, which needs their oncology team? boundary
Understand The cancers.
Clinical.
Types
Types and risk factors.
Types
Types.
- What types of kidney cancer exist, and what are the risk factors? definition
- Is the question about adult kidney cancer, a childhood tumour or a benign mass? boundary
Childhood
Childhood tumours.
Childhood
Childhood.
- What are Wilms tumour and other childhood kidney tumours, in general terms? provenance
- Which entry fits the specific tumour? action
Treat Treatment.
Clinical.
Treatment
Treatment.
Treatment
Treatment.
- What treatments do guidelines recommend, from surgery to targeted and immunotherapies, in general terms? provenance
- Which references are standard? provenance
Outcomes
Outcomes and follow-up.
Outcomes
Outcomes.
- What do statistics say about survival by stage, and how is follow-up organised? provenance
- Which sources are cited? provenance
Context Research and prevention.
Context.
Research
Research.
Research
Research.
- What research is advancing kidney cancer treatment, with findings attributed? provenance
- Which entry fits cancer immunotherapy? action
Prevention
Prevention.
Prevention
Prevention.
- What prevention advice do guidelines give, and what hereditary syndromes need screening? provenance
- Which entry fits hereditary kidney cancer? action
What the second pass must settle
- Should renal cell carcinoma and Wilms tumour be separate primary entries?
- How should guidelines be linked?
- The registry entry has merged aliases naming rare tumours and an adrenal tumour type; should they be split off?