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Research draft

rabies

vr.tr.rabies · XCT.QLT

Let an agent explain rabies and its transmission, relay prevention, post-exposure treatment and control from WHO and veterinary sources, describe rabies in animals and by region, and route anyone exposed to immediate medical care.

Thing Registry Cross-cutting context

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain rabies and its transmission, relay prevention, post-exposure treatment and control from WHO and veterinary sources, describe rabies in animals and by region, and route anyone exposed to immediate medical care.

A viral disease of mammals caused by lyssaviruses, transmitted mainly through the bite of an infected animal, most often dogs in Africa and Asia and bats and wild carnivores elsewhere, causing encephalitis that is almost always fatal once symptoms appear, but preventable by vaccination of animals and by prompt post-exposure prophylaxis in people; rabies kills tens of thousands of people each year, is notifiable, and is targeted for elimination of dog-mediated human deaths by 2030, with countries such as Haiti among those affected.

What it is for: Not applicable; a disease.

It can be explain the disease and transmission; relay prevention and post-exposure care; relay animal control and elimination efforts; route exposures to urgent care.

Distinguishing features

Almost always fatal after onset

Preventable by vaccination

Dog-mediated in most deaths

Global elimination goal

What it looks like

Not a visible object; a fatal encephalitis with agitation or paralysis.

Physical character

human deaths: about 59000 per year - WHO estimates

share from dog bites: about 99 percent

case fatality after symptoms: nearly 100 percent

How it is recognised

Lyssavirus encephalitis from animal bites

Rabies in dogs, bats, wildlife and humans; furious and paralytic forms

Other encephalitides have different causes; distemper in dogs can mimic it

Related models

is a kind of - in registry terms

Lyssavirus infection

is a kind of - in registry terms

central nervous system viral disease

is a kind of - in registry terms

notifiable disease

is prevented by - in animals and people

rabies vaccine

In practice

Families and kinds

rabies in dogs

rabies in bats and wildlife such as foxes and raccoons

human rabies, furious and paralytic

rabies by region such as Haiti and endemic countries

rabies-free countries and import controls

other lyssavirus infections

Identifiers

ICD-11 1C82 rabies

MeSH D011818

Standards and regulation

WHO and WOAH rabies guidance

Zero by 30 global strategic plan

Animal import and quarantine rules

Dog vaccination laws

Failure modes and hazards

Delayed post-exposure prophylaxis

Agents giving personal medical advice instead of routing to care

Under-reporting

Vaccine access gaps

Also called

rabies in animalsRabies in Haiti

Where this came from

wikidata · CC0 1.0

Also registered as vr.tr.rabies

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Help Exposure first.

Safety.

Exposure

After a bite.

Exposure

Exposure.

  1. What should someone do after a possible rabies exposure, per WHO guidance? action
  2. Is the user describing a bite or exposure, which needs immediate medical care? boundary

Prophylaxis

Post-exposure prophylaxis.

Prophylaxis

Prophylaxis.

  1. How does post-exposure prophylaxis work, in general terms? provenance
  2. Which references are standard? provenance
Understand The disease.

Clinical.

Disease

Disease and transmission.

Disease

Disease.

  1. What is rabies, how is it transmitted, and how does it progress? definition
  2. Is the question about rabies or another encephalitis? boundary

Animals

Rabies in animals.

Animals

Animals.

  1. How does rabies affect dogs, bats and wildlife, and how is it recognised? provenance
  2. Which entry fits the specific animal reservoir? action
Control Prevention and control.

Public health.

Vaccination

Vaccination and elimination.

Vaccination

Vaccination.

  1. How do dog vaccination and pre-exposure vaccination prevent rabies, and what is the Zero by 30 goal? provenance
  2. Which sources are cited? provenance

Regions

Regions.

Regions

Regions.

  1. Where is rabies endemic, and what is the situation in countries such as Haiti, with sources? provenance
  2. Which entry fits the specific country? action
Context History and research.

Context.

History

History.

History

History.

  1. How did Pasteur develop the rabies vaccine, and how has control progressed? provenance
  2. Which entry fits the history of vaccination? action

Research

Research.

Research

Research.

  1. What research exists on treatment after onset and on oral wildlife vaccines, with findings attributed? provenance
  2. Which entry fits rabies research? action

What the second pass must settle

  • Should rabies vaccine and post-exposure prophylaxis be separate entries?
  • How should WHO and veterinary sources be linked?
  • The registry entry has merged aliases naming animals and a country; should they be split off?