syphilis
Let an agent explain syphilis in general terms, relay testing, treatment and prevention guidance from health authorities, describe its public health and historical significance including ethical failures in research, and route personal symptoms or results to clinicians and sexual health services.
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain syphilis in general terms, relay testing, treatment and prevention guidance from health authorities, describe its public health and historical significance including ethical failures in research, and route personal symptoms or results to clinicians and sexual health services.
A sexually transmitted infection caused by the bacterium Treponema pallidum, progressing if untreated through primary, secondary, latent and tertiary stages that can affect the skin, mucous membranes, heart, nervous system and other organs, and transmissible from mother to child in pregnancy; it is diagnosed by blood tests and cured by antibiotics, usually penicillin.
What it is for: Not applicable; a disease.
It can be explain stages and transmission in general terms; relay testing and treatment guidance from authorities; relay prevention and partner notification information; route personal questions to clinical services.
Distinguishing features
Caused by Treponema pallidum
Staged course with latency
Curable with penicillin
Congenital transmission preventable by antenatal screening
What it looks like
Not visible as an object; a painless sore in the primary stage, a rash in the secondary stage, and no signs in latency.
Physical character
incubation to primary stage: about 10-90 days - typically about three weeks
new infections: millions per year worldwide - WHO estimates
How it is recognised
Painless chancre at the site of infection
Secondary rash often on palms and soles
Other treponematoses such as yaws are related but distinct infections
Related models
is a kind of - the category
is caused by - the bacterium
is treated by - first-line antibiotic
is confused with - a related treponemal disease
In practice
Families and kinds
primary, secondary, latent and tertiary syphilis
neurosyphilis and ocular syphilis
cardiovascular syphilis
congenital syphilis
syphilis in pregnancy
Identifiers
ICD-10 A50-A53
ICD-11 1A60-1A62
Standards and regulation
WHO guidelines on treatment and antenatal screening
National sexually transmitted infection guidelines
Notifiable disease reporting
Research ethics rules adopted after historical abuses
Failure modes and hazards
Untreated progression to neurological and cardiovascular disease
Congenital syphilis from missed antenatal screening
Stigma delaying testing
Agents giving personal medical advice
Also called
Where this came from
wikidata · CC0 1.0
Also registered as vr.tr.syphilis
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Understand What syphilis is.
General information.
Course
Stages and transmission.
Course
Course.
- How is syphilis transmitted, and what happens in each stage if untreated? definition
- Is the user describing their own symptoms, which need a clinician? boundary
Recognise
Signs.
Recognise
Recognise.
- What signs characterise each stage, and how is it distinguished from other conditions? definition
- Which entry fits another sexually transmitted infection? action
Care Testing and treatment.
Clinical.
Testing
Testing.
Testing
Testing.
- Who should be tested according to guidelines, and how is testing accessed? provenance
- Which services provide testing locally? action
Treatment
Treatment.
Treatment
Treatment.
- What treatment do guidelines describe, and why is follow-up needed? provenance
- Is the presentation free of personal treatment advice? boundary
Prevent Prevention and public health.
Public health.
Prevention
Prevention.
Prevention
Prevention.
- What prevention and partner notification measures do authorities recommend? provenance
- Which entry fits sexual health services? action
Congenital
Pregnancy and screening.
Congenital
Congenital.
- How is congenital syphilis prevented through antenatal screening? provenance
- Which entry fits antenatal care? action
History History and ethics.
Attribution.
History
History.
History
History.
- How did syphilis spread and how was it treated before antibiotics, with debates about origin attributed? provenance
- Which references are standard? provenance
Ethics
Research ethics.
Ethics
Ethics.
- What happened in the Tuskegee and Guatemala studies, and how did they change research ethics? provenance
- Is the presentation accurate and attributed? boundary
What the second pass must settle
- Should congenital syphilis be a separate entry?
- How should national guidelines be linked?
- The registry entry has merged aliases for specific complications; should they be split off?