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Research draft

anosmia

vr.tr.anosmia · XCT.STA

Let an agent explain anosmia and its causes, relay assessment, treatment and impacts from ENT and neurology sources in general terms, describe specific and congenital anosmias, and distinguish anosmia from hyposmia, parosmia and taste loss, routing people with new smell loss to clinicians.

Thing Registry Cross-cutting context

Research draft, second pass

A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.

written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify

Researched by: Claude

Purpose and description

Let an agent explain anosmia and its causes, relay assessment, treatment and impacts from ENT and neurology sources in general terms, describe specific and congenital anosmias, and distinguish anosmia from hyposmia, parosmia and taste loss, routing people with new smell loss to clinicians.

The loss or absence of the sense of smell, whether congenital, acquired through infection, head injury, nasal disease or neurodegeneration, or specific to particular odours such as isovaleric acid, isobutyric acid, musk or freesia flowers in specific anosmias, with merciful anosmia describing the loss that spares a person unpleasant odours; anosmia became widely known as a symptom of COVID-19 and affects safety, nutrition and quality of life.

What it is for: Not applicable; a sensory loss.

It can be explain causes and kinds; relay assessment and treatment; route to clinicians; distinguish related conditions.

Distinguishing features

Smell loss

Many causes

Specific anosmias

Safety and quality of life impact

What it looks like

Not a visible object; inability to smell.

Physical character

prevalence: about 3-5 percent - adults, estimates

COVID-19 smell loss: common early symptom note - 2020-2022

congenital anosmia: about 1 in 10000 note - estimates

How it is recognised

Loss of the sense of smell

Congenital anosmia, specific anosmias for isovaleric acid, isobutyric acid, musk and freesia, merciful anosmia

Hyposmia is reduced smell; parosmia is distorted smell; taste loss is ageusia

Related models

is a kind of - in registry terms

olfaction disorder

is a kind of - in registry terms

sensory loss

is contrasted with - distorted smell

parosmia

was a symptom of - in many cases

COVID-19

In practice

Families and kinds

acquired anosmia from infection including COVID-19

post-traumatic anosmia

anosmia from nasal and sinus disease

congenital anosmia including Kallmann syndrome

specific anosmias for particular odorants

anosmia in neurodegenerative disease

Identifiers

ICD-10 R43.0 anosmia

MeSH D000857 Olfaction Disorders

Standards and regulation

Clinical guidelines for smell disorders

Occupational safety rules for smell-dependent jobs

Failure modes and hazards

Missed underlying causes such as tumours

Agents giving personal medical advice

Safety risks from undetected gas or smoke

Also called

Merciful anosmiacongenital anosmiaanosmia for Isobutyric acidFreesia Flowers, Inability to smellisovaleric acid, Inability to smellmusk, inability to smellanosmia for butyl mercaptan

Where this came from

wikidata · CC0 1.0

Drafted structure

Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.

Understand What anosmia is.

Clinical.

Definition

Definition and kinds.

Definition

Definition.

  1. What is anosmia, and how do acquired, congenital and specific anosmias differ from hyposmia, parosmia and taste loss? definition
  2. Is the user describing new smell loss of their own, which needs a clinician? boundary

Causes

Causes.

Causes

Causes.

  1. What causes anosmia, from viral infection and head injury to sinus disease and neurodegeneration? provenance
  2. Which entry fits the specific cause? action
Care Assessment and treatment.

Clinical.

Assessment

Assessment.

Assessment

Assessment.

  1. How is smell loss assessed with smell tests and imaging, as guidelines describe? provenance
  2. Which references are standard? provenance

Treatment

Treatment.

Treatment

Treatment.

  1. What treatments exist, including smell training, and what is the prognosis, in general terms? provenance
  2. Which sources are cited? provenance
Impact Impact and safety.

Application.

Safety

Safety.

Safety

Safety.

  1. What safety measures do authorities recommend for people who cannot smell gas, smoke or spoiled food? provenance
  2. Which entry fits smoke detector? action

Life

Quality of life.

Life

Life.

  1. How does anosmia affect eating, mood and relationships, as research reports? provenance
  2. Which entry fits smell loss support organisations? action
Context Science and history.

Context.

Science

Specific anosmias.

Science

Science.

  1. What do specific anosmias for musk, isovaleric acid and other odorants reveal about olfactory receptors? provenance
  2. Which entry fits olfactory receptor? action

History

History.

History

History.

  1. How did understanding of anosmia develop, and what did COVID-19 change? provenance
  2. Which entry fits the history of olfaction research? action

What the second pass must settle

  • Should specific anosmia and congenital anosmia be separate primary entries?
  • How should clinical sources be linked?
  • The registry entry has merged aliases naming specific odorant anosmias; should they be split off?