bone marrow
Let an agent explain bone marrow and its functions, relay clinical information on marrow sampling, disorders and transplantation from clinical sources, describe culinary use, and route personal questions to clinicians.
Research draft, second pass
A second pass drafted this model: the structure a model of this thing needs, and what is known about it in the world. The line under this one says how the second half was obtained - researched against sources, or recalled without web access, in which case nothing here was read anywhere and every claim is a lead to verify. Unreviewed either way.
written by Claude from model knowledge without web access - no source was read, every claim is a lead to verify
Researched by: Claude
Purpose and description
Let an agent explain bone marrow and its functions, relay clinical information on marrow sampling, disorders and transplantation from clinical sources, describe culinary use, and route personal questions to clinicians.
The soft tissue inside bones, consisting of red marrow that produces blood cells and yellow marrow rich in fat, found in the cavities of long bones such as the femur and humerus and in the spongy bone of the pelvis, ribs and vertebrae; bone marrow is the site of haematopoiesis, is sampled to diagnose blood disorders, is transplanted to treat leukaemia and other diseases, and is eaten as food in many cuisines.
What it is for: Producing blood cells; also food.
It can be explain structure and function; relay clinical sampling and transplant information; describe culinary use; route personal questions to clinicians.
Distinguishing features
Haematopoietic tissue
Red and yellow types
Transplantable
Site of blood cancers
What it looks like
Soft red or yellow tissue inside bones, seen in cut bones and in marrow samples.
Physical character
share of body mass: about 4 percent - adult
blood cells produced: hundreds of billions per day - adult
How it is recognised
Tissue inside bone cavities
Red marrow makes blood; yellow marrow stores fat
Bone itself and the spinal cord are different tissues
Related models
is a kind of - in registry terms
is a kind of - in registry terms
produces - by haematopoiesis
is transplanted in - for blood diseases
In practice
Families and kinds
red marrow, myeloid tissue
yellow marrow
marrow by bone: femur, humerus, pelvis, sternum
human and animal marrow, including cattle marrow as food
marrow as a transplant source
Identifiers
MeSH D001853 bone marrow
TA2 bone marrow Terminologia Anatomica
Standards and regulation
Transplant and donor registry regulations
Clinical standards for marrow biopsy
Food safety rules for marrow, including BSE-related controls
Failure modes and hazards
Marrow failure and blood cancers
Transplant complications such as graft-versus-host disease
Agents giving personal medical advice
Also called
Where this came from
wikidata · CC0 1.0
Drafted structure
Bundle to layer to finding to question, as the second pass will find it: 4 bundles · 8 layers · 8 findings · 16 questions.
Biology Structure and function.
Science.
Structure
Structure.
Structure
Structure.
- What are red and yellow marrow, and where are they found? definition
- Is the question about marrow, bone or the spinal cord? boundary
Function
Haematopoiesis.
Function
Function.
- How does marrow produce blood cells? definition
- Which entry fits haematopoiesis? action
Clinical Disorders and sampling.
Clinical.
Disorders
Disorders.
Disorders
Disorders.
- Which disorders affect the marrow, from leukaemia to aplastic anaemia, in general terms? provenance
- Is the user asking about their own condition, which needs a clinician? boundary
Sampling
Biopsy and tests.
Sampling
Sampling.
- How and why is marrow sampled, per clinical sources? provenance
- Which references are standard? provenance
Transplant Transplantation and donation.
Practice.
Transplant
Transplantation.
Transplant
Transplant.
- How do marrow and stem cell transplants work, and what do they treat? provenance
- Which entry fits stem cell transplantation? action
Donation
Donation.
Donation
Donation.
- How do donor registries work, and what does donation involve? provenance
- Which entry fits a specific donor registry? action
Context Food and history.
Context.
Food
Marrow as food.
Food
Food.
- How is bone marrow used in cuisines, and what safety rules apply? provenance
- Which entry fits offal? action
History
History.
History
History.
- How was the role of marrow in blood formation discovered, and how did transplantation develop? provenance
- Which sources are cited? provenance
What the second pass must settle
- Should haematopoiesis and transplantation be the linked primary entries?
- How should donor registries be linked?
- The registry entry has merged aliases naming marrow by bone and as food; should they be split off?